Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells

FASEB Journal

Volumn 23, Issue 6, 2009, Pages 1935-1945

  Zeng, Fenghua ^a   Xu, Jie ^a   Harris, Raymond C ^a,b,c  

^a VANDERBILT UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

E3 ubiquitin ligase; Nuclear translocation; PI3 kinase; PY motif mutation

Indexed keywords

CHLOROQUINE; EPIDERMAL GROWTH FACTOR RECEPTOR 4; LACTACYSTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; PROTEIN SH2; UBIQUITIN PROTEIN LIGASE NEDD4; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; ISOPROTEIN; NEDD4 UBIQUITIN PROTEIN LIGASES; PHORBOL 13 ACETATE 12 MYRISTATE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; BINDING ASSAY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; IMMUNOPRECIPITATION; IN VITRO STUDY; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; UBIQUITINATION; ANIMAL; CELL CULTURE; DOG; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID MOTIFS; ANIMALS; CELLS, CULTURED; DOGS; ENZYME INHIBITORS; HUMANS; LYSOSOMES; MUTAGENESIS, SITE-DIRECTED; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; TETRADECANOYLPHORBOL ACETATE; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 67649311930     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-121947     Document Type: Article

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