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Volumn 27, Issue 6, 2007, Pages 2180-2188

Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 3; NEU DIFFERENTIATION FACTOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEIN USP8; REGULATOR PROTEIN; THREONINE; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE NRDP1; UNCLASSIFIED DRUG;

EID: 33947245587     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01245-06     Document Type: Article
Times cited : (99)

References (57)
  • 1
    • 0032561206 scopus 로고    scopus 로고
    • Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase
    • Adam, L., R. Vadlamudi, S. B. Kondapaka, J. Chernoff, J. Mendelsohn, and R. Kumar. 1998. Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase. J. Biol. Chem. 273:28238-28246.
    • (1998) J. Biol. Chem , vol.273 , pp. 28238-28246
    • Adam, L.1    Vadlamudi, R.2    Kondapaka, S.B.3    Chernoff, J.4    Mendelsohn, J.5    Kumar, R.6
  • 3
    • 0030795612 scopus 로고    scopus 로고
    • The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
    • Alroy, I., and Y. Yarden. 1997. The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions. FEBS Lett. 410:83-86.
    • (1997) FEBS Lett , vol.410 , pp. 83-86
    • Alroy, I.1    Yarden, Y.2
  • 4
    • 0029912203 scopus 로고    scopus 로고
    • All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
    • Baulida, J., M. H. Kraus, M. Alimandi, P. P. Di Fiore, and G. Carpenter. 1996. All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem. 271:5251-5257.
    • (1996) J. Biol. Chem , vol.271 , pp. 5251-5257
    • Baulida, J.1    Kraus, M.H.2    Alimandi, M.3    Di Fiore, P.P.4    Carpenter, G.5
  • 5
    • 0031562676 scopus 로고    scopus 로고
    • Heregulin degradation in the absence of rapid receptor-mediated internalization
    • Baulida, J., and G. Carpenter. 1997. Heregulin degradation in the absence of rapid receptor-mediated internalization. Exp. Cell Res. 232:167-172.
    • (1997) Exp. Cell Res , vol.232 , pp. 167-172
    • Baulida, J.1    Carpenter, G.2
  • 6
    • 33646171781 scopus 로고    scopus 로고
    • Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII
    • Bowers, K., S. C. Piper, M. A. Edeling, S. R. Gray, D. J. Owen, P. J. Lehner, and J. P. Luzio. 2006. Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J. Biol. Chem. 281:5094-5105.
    • (2006) J. Biol. Chem , vol.281 , pp. 5094-5105
    • Bowers, K.1    Piper, S.C.2    Edeling, M.A.3    Gray, S.R.4    Owen, D.J.5    Lehner, P.J.6    Luzio, J.P.7
  • 7
    • 0035368610 scopus 로고    scopus 로고
    • Neuregulin and ErbB receptor signaling pathways in the nervous system
    • Buonanno, A., and G. D. Fischbach. 2001. Neuregulin and ErbB receptor signaling pathways in the nervous system. Curr. Opin. Neurobiol. 11:287-296.
    • (2001) Curr. Opin. Neurobiol , vol.11 , pp. 287-296
    • Buonanno, A.1    Fischbach, G.D.2
  • 8
    • 0030919509 scopus 로고    scopus 로고
    • Neuregulins and their receptors: A versatile signaling module in organogenesis and oncogenesis
    • Burden, S., and Y. Yarden. 1997. Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis. Neuron 18:847-855.
    • (1997) Neuron , vol.18 , pp. 847-855
    • Burden, S.1    Yarden, Y.2
  • 9
    • 0028176477 scopus 로고
    • A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling
    • Carraway, K. L., III, and L. C. Cantley. 1994. A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling. Cell 78:5-8.
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway III, K.L.1    Cantley, L.C.2
  • 10
    • 0028949081 scopus 로고
    • Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3
    • Carraway, K. L., III, S. P. Soltoff, A. J. Diamonti, and L. C. Cantley. 1995. Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3. J. Biol. Chem. 270:7111-7116.
    • (1995) J. Biol. Chem , vol.270 , pp. 7111-7116
    • Carraway III, K.L.1    Soltoff, S.P.2    Diamonti, A.J.3    Cantley, L.C.4
  • 11
    • 0034949705 scopus 로고    scopus 로고
    • c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route
    • de Melker, A. A., G. van der Horst, J. Calafat, H. Jansen, and J. Borst. 2001. c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route. J. Cell Sci. 114:2167-2178.
    • (2001) J. Cell Sci , vol.114 , pp. 2167-2178
    • de Melker, A.A.1    van der Horst, G.2    Calafat, J.3    Jansen, H.4    Borst, J.5
  • 13
    • 0038362292 scopus 로고    scopus 로고
    • When ubiquitin meets ubiquitin receptors: A signalling connection
    • Di Fiore, P. P., S. Polo, and K. Hofmann. 2003. When ubiquitin meets ubiquitin receptors: a signalling connection. Nat. Rev. Mol. Cell Biol. 4:491-497.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 491-497
    • Di Fiore, P.P.1    Polo, S.2    Hofmann, K.3
  • 14
    • 33745830104 scopus 로고    scopus 로고
    • The mucin Muc4 potentiates neuregulin signaling by increasing the cell surface populations of ErbB2 and ErbB3
    • Funes, M., J. K. Miller, C. Lai, K. L. Carraway III, and C. Sweeney. 2006. The mucin Muc4 potentiates neuregulin signaling by increasing the cell surface populations of ErbB2 and ErbB3. J. Biol. Chem. 281:19310-19319.
    • (2006) J. Biol. Chem , vol.281 , pp. 19310-19319
    • Funes, M.1    Miller, J.K.2    Lai, C.3    Carraway III, K.L.4    Sweeney, C.5
  • 17
    • 0038394715 scopus 로고    scopus 로고
    • Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
    • Haglund, K., S. Sigismund, S. Polo, I. Szymkiewicz, P. P. Di Fiore, and I. Dikic. 2003. Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nat. Cell Biol. 5:461-466.
    • (2003) Nat. Cell Biol , vol.5 , pp. 461-466
    • Haglund, K.1    Sigismund, S.2    Polo, S.3    Szymkiewicz, I.4    Di Fiore, P.P.5    Dikic, I.6
  • 18
    • 1542373897 scopus 로고    scopus 로고
    • Distinct monoubiquitin signals in receptor endocytosis
    • Haglund, K., P. P. Di Fiore, and I. Dikic. 2003. Distinct monoubiquitin signals in receptor endocytosis. Trends Biochem. Sci. 28:598-603.
    • (2003) Trends Biochem. Sci , vol.28 , pp. 598-603
    • Haglund, K.1    Di Fiore, P.P.2    Dikic, I.3
  • 19
    • 0034293169 scopus 로고    scopus 로고
    • Heregulin regulates the actin cytoskeleton and promotes invasive properties in breast cancer cell lines
    • Hijazi, M. M., E. W. Thompson, C. Tang, P. Coopman, J. A. Torri, D. Yang, S. C. Mueller, and R. Lupu. 2000. Heregulin regulates the actin cytoskeleton and promotes invasive properties in breast cancer cell lines. Int. J. Oncol. 17:629-641.
    • (2000) Int. J. Oncol , vol.17 , pp. 629-641
    • Hijazi, M.M.1    Thompson, E.W.2    Tang, C.3    Coopman, P.4    Torri, J.A.5    Yang, D.6    Mueller, S.C.7    Lupu, R.8
  • 20
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro, T., R. R. Beerli, F. Maurer, M. Koziczak, C. F. Barbas III, and N. E. Hynes. 2003. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc. Natl. Acad. Sci. USA 100:8933-8938.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3    Koziczak, M.4    Barbas III, C.F.5    Hynes, N.E.6
  • 21
    • 0037429725 scopus 로고    scopus 로고
    • The ErbB receptors and their role in cancer progression
    • Holbro, T., G. Civenni, and N. E. Hynes. 2003. The ErbB receptors and their role in cancer progression. Exp. Cell Res. 284:99-110.
    • (2003) Exp. Cell Res , vol.284 , pp. 99-110
    • Holbro, T.1    Civenni, G.2    Hynes, N.E.3
  • 22
    • 1642422374 scopus 로고    scopus 로고
    • Association with membrane protrusions makes ErbB2 an internalization-resistant receptor
    • Hommelgaard, A. M., M. Lerdrup, and B. van Deurs. 2004. Association with membrane protrusions makes ErbB2 an internalization-resistant receptor. Mol. Biol. Cell 15:1557-1567.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1557-1567
    • Hommelgaard, A.M.1    Lerdrup, M.2    van Deurs, B.3
  • 23
    • 33644852909 scopus 로고    scopus 로고
    • Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
    • Huang, F., D. Kirkpatrick, X. Jiang, S. Gygi, and A. Sorkin. 2006. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol. Cell 21:737-748.
    • (2006) Mol. Cell , vol.21 , pp. 737-748
    • Huang, F.1    Kirkpatrick, D.2    Jiang, X.3    Gygi, S.4    Sorkin, A.5
  • 24
    • 0041845231 scopus 로고    scopus 로고
    • Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions
    • Katome, T., T. Obata, R. Matsushima, N. Masuyama, L. C. Cantley, Y. Gotoh, K. Kishi, H. Shiota, and Y. Ebina. 2003. Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions. J. Biol. Chem. 278:28312-28323.
    • (2003) J. Biol. Chem , vol.278 , pp. 28312-28323
    • Katome, T.1    Obata, T.2    Matsushima, R.3    Masuyama, N.4    Cantley, L.C.5    Gotoh, Y.6    Kishi, K.7    Shiota, H.8    Ebina, Y.9
  • 25
    • 0036902646 scopus 로고    scopus 로고
    • Receptor downregulation and multivesicular-body sorting
    • Katzmann, D. J., G. Odorizzi, and S. D. Emr. 2002. Receptor downregulation and multivesicular-body sorting. Nat. Rev. Mol. Cell Biol. 3:893-905.
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 893-905
    • Katzmann, D.J.1    Odorizzi, G.2    Emr, S.D.3
  • 27
    • 0029917264 scopus 로고    scopus 로고
    • Coupling of the c-Cbl protooncogene product to ErbB-1/ EGF-receptor but not to other ErbB proteins
    • Levkowitz, G., L. N. Klapper, E. Tzahar, A. Freywald, M. Sela, and Y. Yarden. 1996. Coupling of the c-Cbl protooncogene product to ErbB-1/ EGF-receptor but not to other ErbB proteins. Oncogene 12:1117-1125.
    • (1996) Oncogene , vol.12 , pp. 1117-1125
    • Levkowitz, G.1    Klapper, L.N.2    Tzahar, E.3    Freywald, A.4    Sela, M.5    Yarden, Y.6
  • 29
    • 0034614652 scopus 로고    scopus 로고
    • The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor
    • Lill, N. L., P. Douillard, R. A. Awwad, S. Ota, M. L. Lupber, Jr., S. Miyake, N. Meissner-Lula, V. W. Hsu, and H. Band. 2000. The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor. J. Biol. Chem. 275:367-377.
    • (2000) J. Biol. Chem , vol.275 , pp. 367-377
    • Lill, N.L.1    Douillard, P.2    Awwad, R.A.3    Ota, S.4    Lupber Jr., M.L.5    Miyake, S.6    Meissner-Lula, N.7    Hsu, V.W.8    Band, H.9
  • 30
    • 22244453690 scopus 로고    scopus 로고
    • Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
    • Longva, K. E., N. M. Pedersen, C. Haslekas, E. Stang, and I. H. Madshus. 2005. Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2. Int. J. Cancer 116:359-367.
    • (2005) Int. J. Cancer , vol.116 , pp. 359-367
    • Longva, K.E.1    Pedersen, N.M.2    Haslekas, C.3    Stang, E.4    Madshus, I.H.5
  • 31
    • 2942628182 scopus 로고    scopus 로고
    • ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance
    • Louie, M. C., J. X. Zou, A. Rabinovicb, and H. W. Chen. 2004. ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Mol. Cell. Biol. 24:5157-5171.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 5157-5171
    • Louie, M.C.1    Zou, J.X.2    Rabinovicb, A.3    Chen, H.W.4
  • 32
    • 27644438783 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes
    • Mizuno, E., T. Iura, A. Mukai, T. Yoshimori, N. Kitamura, and M. Komada. 2005. Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes. Mol. Biol. Cell 16:5163-5174.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5163-5174
    • Mizuno, E.1    Iura, T.2    Mukai, A.3    Yoshimori, T.4    Kitamura, N.5    Komada, M.6
  • 33
    • 33947271514 scopus 로고    scopus 로고
    • A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes
    • Mizuno, E., K. Kobayashi, A. Yamamoto, N. Kitamura, and M. Komada. 2006. A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes. Traffic 12:12.
    • (2006) Traffic , vol.12 , pp. 12
    • Mizuno, E.1    Kobayashi, K.2    Yamamoto, A.3    Kitamura, N.4    Komada, M.5
  • 34
    • 0037677208 scopus 로고    scopus 로고
    • Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation
    • Mosesson, Y., K. Shtiegman, M. Katz, Y. Zwang, G. Vereb, J. Szollosi, and Y. Yarden. 2003. Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation. J. Biol. Chem. 278:21323- 21326.
    • (2003) J. Biol. Chem , vol.278 , pp. 21323-21326
    • Mosesson, Y.1    Shtiegman, K.2    Katz, M.3    Zwang, Y.4    Vereb, G.5    Szollosi, J.6    Yarden, Y.7
  • 35
    • 3042611780 scopus 로고    scopus 로고
    • Oncogenic growth factor receptors: Implications for signal transduction therapy
    • Mosesson, Y., and Y. Yarden. 2004. Oncogenic growth factor receptors: implications for signal transduction therapy. Semin. Cancer Biol. 14:262-270.
    • (2004) Semin. Cancer Biol , vol.14 , pp. 262-270
    • Mosesson, Y.1    Yarden, Y.2
  • 36
    • 0031730476 scopus 로고    scopus 로고
    • Expression of c-erbB3 protein in primary breast carcinomas
    • Naidu, R., M. Yadav, S. Nair, and M. K. Kutty. 1998. Expression of c-erbB3 protein in primary breast carcinomas. Br. J. Cancer 78:1385-1390.
    • (1998) Br. J. Cancer , vol.78 , pp. 1385-1390
    • Naidu, R.1    Yadav, M.2    Nair, S.3    Kutty, M.K.4
  • 37
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye, M. A., R. M. Neve, H. A. Lane, and N. E. Hynes. 2000. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. 19:3159-3167.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 38
    • 0038386452 scopus 로고    scopus 로고
    • Escape from Cbl-mediated downregulation: A recurrent theme for oncogenic deregulation of receptor tyrosine kinases
    • Peschard, P., and M. Park. 2003. Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases. Cancer Cell 3:519-523.
    • (2003) Cancer Cell , vol.3 , pp. 519-523
    • Peschard, P.1    Park, M.2
  • 39
    • 0037069388 scopus 로고    scopus 로고
    • Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
    • Qiu, X. B., and A. L. Goldberg. 2002. Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3. Proc. Natl. Acad. Sci. USA 99:14843-14848.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14843-14848
    • Qiu, X.B.1    Goldberg, A.L.2
  • 40
    • 0028328538 scopus 로고
    • The type I growth factor receptors in human breast cancer
    • Rajkumar, T., and W. J. Gullick. 1994. The type I growth factor receptors in human breast cancer. Breast Cancer Res. Treat. 29:3-9.
    • (1994) Breast Cancer Res. Treat , vol.29 , pp. 3-9
    • Rajkumar, T.1    Gullick, W.J.2
  • 41
    • 0037163042 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation
    • Ravid, T., C. Sweeney, P. Gee, K. L. Carraway III, and T. Goldkorn. 2002. Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation. J. Biol. Chem. 277:31214-31219.
    • (2002) J. Biol. Chem , vol.277 , pp. 31214-31219
    • Ravid, T.1    Sweeney, C.2    Gee, P.3    Carraway III, K.L.4    Goldkorn, T.5
  • 42
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese, D. J., II, and D. F. Stern. 1998. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 20:41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese II, D.J.1    Stern, D.F.2
  • 43
    • 33646788800 scopus 로고    scopus 로고
    • The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation
    • Row, P. E., I. A. Prior, J. McCullough, M. J. Clague, and S. Urbe. 2006. The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation. J. Biol. Chem. 281:12618-12624.
    • (2006) J. Biol. Chem , vol.281 , pp. 12618-12624
    • Row, P.E.1    Prior, I.A.2    McCullough, J.3    Clague, M.J.4    Urbe, S.5
  • 44
    • 0037329054 scopus 로고    scopus 로고
    • The role of ubiquitylation in signaling by growth factors: Implications to cancer
    • Shtiegman, K., and Y. Yarden. 2003. The role of ubiquitylation in signaling by growth factors: implications to cancer. Semin. Cancer Biol. 13:29-40.
    • (2003) Semin. Cancer Biol , vol.13 , pp. 29-40
    • Shtiegman, K.1    Yarden, Y.2
  • 45
    • 0033561296 scopus 로고    scopus 로고
    • Siegel, P. M., E. D. Ryan, R. D. Cardiff, and W. J. Muller. 1999. Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. EMBO J. 18:2149-2164.
    • Siegel, P. M., E. D. Ryan, R. D. Cardiff, and W. J. Muller. 1999. Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. EMBO J. 18:2149-2164.
  • 46
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D. J., G. M. Clark, S. G. Wong, W. J. Levin, A. Ullrich, and W. L. McGuire. 1987. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 49
    • 0037429727 scopus 로고    scopus 로고
    • ErbBs in mammary development
    • Stern, D. F. 2003. ErbBs in mammary development. Exp. Cell Res. 284:89-98.
    • (2003) Exp. Cell Res , vol.284 , pp. 89-98
    • Stern, D.F.1
  • 50
    • 1342301560 scopus 로고    scopus 로고
    • Negative regulation of ErbB family receptor tyrosine kinases
    • Sweeney, C., and K. L. Carraway III. 2004. Negative regulation of ErbB family receptor tyrosine kinases. Br. J. Cancer 90:289-293.
    • (2004) Br. J. Cancer , vol.90 , pp. 289-293
    • Sweeney, C.1    Carraway III, K.L.2
  • 52
    • 0035316576 scopus 로고    scopus 로고
    • Cbl: Many adaptations to regulate protein tyrosine kinases. Nat. Rev. Mol. Cell Biol
    • Thien, C. B., and W. Y. Langdon. 2001. Cbl: many adaptations to regulate protein tyrosine kinases. Nat. Rev. Mol. Cell Biol. 2:294-307.
    • (2001) , vol.2 , pp. 294-307
    • Thien, C.B.1    Langdon, W.Y.2
  • 53
    • 0032948524 scopus 로고    scopus 로고
    • Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation
    • Wang, Z., L. Zhang, T. K. Yeung, and X. Chen. 1999. Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol. Biol. Cell 10:1621-1636.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 1621-1636
    • Wang, Z.1    Zhang, L.2    Yeung, T.K.3    Chen, X.4
  • 54
    • 0037429692 scopus 로고    scopus 로고
    • Trafficking of the ErbB receptors and its influence on signaling
    • Wiley, H. S. 2003. Trafficking of the ErbB receptors and its influence on signaling. Exp. Cell Res. 284:78-88.
    • (2003) Exp. Cell Res , vol.284 , pp. 78-88
    • Wiley, H.S.1
  • 55
    • 4344646977 scopus 로고    scopus 로고
    • Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8
    • Wu, X., L. Yen, L. Irwin, C. Sweeney, and K. L. Carraway III. 2004. Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8. Mol. Cell. Biol. 24:7748-7757.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 7748-7757
    • Wu, X.1    Yen, L.2    Irwin, L.3    Sweeney, C.4    Carraway III, K.L.5
  • 56
    • 0030879101 scopus 로고    scopus 로고
    • Xu, F. J., S. Stack, C. Boyer, K. O'Briant, R. Whitaker, G. B. Mills, Y. H. Yu, and R. C. Bast, Jr. 1997. Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): increased invasiveness may contribute to poor prognosis. Clin. Cancer Res. 3:1629-1634.
    • Xu, F. J., S. Stack, C. Boyer, K. O'Briant, R. Whitaker, G. B. Mills, Y. H. Yu, and R. C. Bast, Jr. 1997. Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): increased invasiveness may contribute to poor prognosis. Clin. Cancer Res. 3:1629-1634.


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