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Volumn 5, Issue 5, 2013, Pages 912-925

The Toxicological Impacts of the Fusarium mycotoxin, Deoxynivalenol, in Poultry Flocks with Special Reference to Immunotoxicity

Author keywords

Cytokines; Deoxynivalenol; Fusarium mycotoxin; Gut immunity; Immune responses; Poultry

Indexed keywords

AVIAN INFECTIOUS BRONCHITIS VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN A; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; MYCOTOXIN; NEWCASTLE DISEASE VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS VACCINE; VOMITOXIN; ZEARALENONE;

EID: 84877048119     PISSN: 20726651     EISSN: None     Source Type: Journal    
DOI: 10.3390/toxins5050912     Document Type: Review
Times cited : (76)

References (80)
  • 1
    • 0347716454 scopus 로고    scopus 로고
    • The impact of low concentrations of aflatoxin, deoxynivalenol or fumonisin in diets on growing pigs and poultry
    • Dersjant-Li, Y.; Verstegen, M.W.A.; Gerrits, W.J.J. The impact of low concentrations of aflatoxin, deoxynivalenol or fumonisin in diets on growing pigs and poultry. Nutr. Res. Rev. 2003, 16, 223-239.
    • (2003) Nutr. Res. Rev , vol.16 , pp. 223-239
    • Dersjant-Li, Y.1    Verstegen, M.W.A.2    Gerrits, W.J.J.3
  • 2
    • 0242539883 scopus 로고    scopus 로고
    • Absorption metabolism and excretion of 3-acetyl DON in pigs
    • Eriksen, G.S.; Pettersson, H.; Lindberg, J.E., Absorption metabolism and excretion of 3-acetyl DON in pigs. Arch. Tierernähr. 2003, 57, 335-345.
    • (2003) Arch. Tierernähr , vol.57 , pp. 335-345
    • Eriksen, G.S.1    Pettersson, H.2    Lindberg, J.E.3
  • 5
    • 4043138556 scopus 로고    scopus 로고
    • Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens
    • Swamy, H.V.L.N.; Smith, T.K.; Karrow, N.A.; Boermans, H.J. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens. Poult. Sci. 2004, 83, 533-543.
    • (2004) Poult. Sci , vol.83 , pp. 533-543
    • Swamy, H.V.L.N.1    Smith, T.K.2    Karrow, N.A.3    Boermans, H.J.4
  • 7
    • 78149245857 scopus 로고    scopus 로고
    • Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase dependent mechanism
    • Pinton, P.; Braicu, C.; Nougayrede, J.P.; Laffitte, J.; Taranu, I.; Oswald, I.P. Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase dependent mechanism. J. Nutr. 2010, 140, 1956-1962.
    • (2010) J. Nutr , vol.140 , pp. 1956-1962
    • Pinton, P.1    Braicu, C.2    Nougayrede, J.P.3    Laffitte, J.4    Taranu, I.5    Oswald, I.P.6
  • 8
    • 81855180647 scopus 로고    scopus 로고
    • Expression of immune relevant genes in pigs under the influence of low doses of deoxynivalenol (DON)
    • Becker, C.; Reiter, M.; Pfaffl, M.W.; Meyer, H.H.D.; Bauer, J.; Meyer, K.H.D. Expression of immune relevant genes in pigs under the influence of low doses of deoxynivalenol (DON). Mycotoxin Res. 2011, 27, 287-293.
    • (2011) Mycotoxin Res , vol.27 , pp. 287-293
    • Becker, C.1    Reiter, M.2    Pfaffl, M.W.3    Meyer, H.H.D.4    Bauer, J.5    Meyer, K.H.D.6
  • 9
    • 0037432624 scopus 로고    scopus 로고
    • Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions
    • Pestka, J.J. Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions. Toxicol. Lett. 2003, 140, 287-295.
    • (2003) Toxicol. Lett , vol.140 , pp. 287-295
    • Pestka, J.J.1
  • 10
    • 19444365938 scopus 로고    scopus 로고
    • Effects of trichothecene mycotoxins on eukaryotic cells: A review
    • Rocha, O.; Ansari, K.; Doohan, F.M. Effects of trichothecene mycotoxins on eukaryotic cells: A review. Food Add. Contam. 2005, 22, 369-378.
    • (2005) Food Add. Contam , vol.22 , pp. 369-378
    • Rocha, O.1    Ansari, K.2    Doohan, F.M.3
  • 11
    • 4444268646 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox
    • Pestka, J.J.; Zhou, H.R.; Moon, Y.; Chung, Y.J. Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox. Toxicol. Lett. 2004, 153, 61-73.
    • (2004) Toxicol. Lett , vol.153 , pp. 61-73
    • Pestka, J.J.1    Zhou, H.R.2    Moon, Y.3    Chung, Y.J.4
  • 12
    • 1842855995 scopus 로고    scopus 로고
    • Toxicological evaluation of trichothecenes in animal feed
    • Eriksen, G.S.; Pettersson, H. Toxicological evaluation of trichothecenes in animal feed. Anim. Feed Sci. Technol. 2004, 114, 205-239.
    • (2004) Anim. Feed Sci. Technol , vol.114 , pp. 205-239
    • Eriksen, G.S.1    Pettersson, H.2
  • 13
    • 84857946254 scopus 로고    scopus 로고
    • Ameliorative effect of a microbial feed additive on infectious bronchitis virus antibody titer and stress index in broiler chicks fed deoxynivalenol
    • Ghareeb, K.; Awad, W.A.; Böhm, J. Ameliorative effect of a microbial feed additive on infectious bronchitis virus antibody titer and stress index in broiler chicks fed deoxynivalenol. Poult. Sci. 2012, 91, 800-807.
    • (2012) Poult. Sci , vol.91 , pp. 800-807
    • Ghareeb, K.1    Awad, W.A.2    Böhm, J.3
  • 14
    • 0036834145 scopus 로고    scopus 로고
    • Effect of addition of a detoxifying agent to laying hen diets containing uncontaminated or Fusarium toxin contaminated maize on performance of hens and on carryover of zearalenone
    • Dänicke, S.; Ueberschär, K.H.; Matthes, S.; Halle, I.; Valenta, H.; Flachowsky, G. Effect of addition of a detoxifying agent to laying hen diets containing uncontaminated or Fusarium toxin contaminated maize on performance of hens and on carryover of zearalenone. Poult. Sci. 2002, 81, 1671-1680.
    • (2002) Poult. Sci , vol.81 , pp. 1671-1680
    • Dänicke, S.1    Ueberschär, K.H.2    Matthes, S.3    Halle, I.4    Valenta, H.5    Flachowsky, G.6
  • 15
    • 84877059434 scopus 로고    scopus 로고
    • Chronic Effects of Deoxynivalenol on Plasma Cytokines and Vaccine Response of Broiler Chickens
    • für Mykotoxin Forschung e.V., Braunschweig, Germany, 14-16 May
    • Awad, W.A.; Ghareeb, K.; Chimidtseren, S.; Strasser, A.; Hess, M.; Böhm, J. Chronic Effects of Deoxynivalenol on Plasma Cytokines and Vaccine Response of Broiler Chickens. In Proceedings of the 34th Mykotoxin-Workshops der Ges. für Mykotoxin Forschung e.V., Braunschweig, Germany, 14-16 May 2012; p. 29.
    • (2012) Proceedings of the 34th Mykotoxin-Workshops Der Ges , pp. 29
    • Awad, W.A.1    Ghareeb, K.2    Chimidtseren, S.3    Strasser, A.4    Hess, M.5    Böhm, J.6
  • 16
    • 9744238132 scopus 로고    scopus 로고
    • Effects of deoxynivalenol on general performance and electrophysiological properties of intestinal mucosa of broiler chickens
    • Awad, W.A.; Böhm, J.; Razzazi-Fazeli, E.; Hulan, H.W.; Zentek, J. Effects of deoxynivalenol on general performance and electrophysiological properties of intestinal mucosa of broiler chickens. Poult. Sci. 2004, 83, 1964-1972.
    • (2004) Poult. Sci , vol.83 , pp. 1964-1972
    • Awad, W.A.1    Böhm, J.2    Razzazi-Fazeli, E.3    Hulan, H.W.4    Zentek, J.5
  • 17
    • 33745520070 scopus 로고    scopus 로고
    • Effect of addition of a probiotic microorganism to broiler diets contaminated with deoxynivalenol on performance and histological alterations of intestinal villi of broiler chickens
    • Awad, W.A.; Razzazi-Fazeli, E.; Böhm, J.; Ghareeb, K.; Zentek, J. Effect of addition of a probiotic microorganism to broiler diets contaminated with deoxynivalenol on performance and histological alterations of intestinal villi of broiler chickens. Poult. Sci. 2006, 85, 974-979.
    • (2006) Poult. Sci , vol.85 , pp. 974-979
    • Awad, W.A.1    Razzazi-Fazeli, E.2    Böhm, J.3    Ghareeb, K.4    Zentek, J.5
  • 18
    • 33645353619 scopus 로고    scopus 로고
    • Effects of feeding deoxynivalenol contaminated wheat on growth performance, organ weights and histological parameters of the intestine of broiler chickens
    • Awad, W.A.; Böhm, J.; Razzazi-Fazeli, E.; Zentek, J. Effects of feeding deoxynivalenol contaminated wheat on growth performance, organ weights and histological parameters of the intestine of broiler chickens. J. Anim. Nutr. Anim. Physiol. 2006, 90, 32-37.
    • (2006) J. Anim. Nutr. Anim. Physiol , vol.90 , pp. 32-37
    • Awad, W.A.1    Böhm, J.2    Razzazi-Fazeli, E.3    Zentek, J.4
  • 19
    • 77952309076 scopus 로고    scopus 로고
    • Morphological changes in the intestine of broiler breeder pullets fed diets naturally contaminated with Fusarium mycotoxins with or without coccidial challenge
    • Girgis, G.N.; Barta, J.R.; Brash, M.; Smith, T.K. Morphological changes in the intestine of broiler breeder pullets fed diets naturally contaminated with Fusarium mycotoxins with or without coccidial challenge. Avian Dis. 2010, 54, 67-73.
    • (2010) Avian Dis , vol.54 , pp. 67-73
    • Girgis, G.N.1    Barta, J.R.2    Brash, M.3    Smith, T.K.4
  • 20
    • 84877044536 scopus 로고    scopus 로고
    • Anytime Publishing Services: Leicestershire, UK, Volume
    • Romer Labs' Guide to Mycotoxins. Mycotoxins-An Overview; Richard, J.L., Ed.; Anytime Publishing Services: Leicestershire, UK, 2000; Volume 1, pp. 1-48.
    • (2000) Romer Labs' Guide to Mycotoxins. Mycotoxins-An Overview , vol.1 , pp. 1-48
  • 21
    • 84877077361 scopus 로고    scopus 로고
    • CAST, Council for Agricultural Science and Technology, (Task Force Report, No. 139); Council for Agricultural Science and Technology: Ames, IA, USA, Volume
    • CAST, Council for Agricultural Science and Technology. Mycotoxins-Risks in Plant, Animal and Human Systems; (Task Force Report, No. 139); Council for Agricultural Science and Technology: Ames, IA, USA, 2003; Volume 10, pp. 1-191.
    • (2003) Mycotoxins-Risks In Plant, Animal and Human Systems , vol.10 , pp. 1-191
  • 22
    • 35948944283 scopus 로고    scopus 로고
    • Some major mycotoxins and their mycotoxicoses-An overview
    • Richard, J.L. Some major mycotoxins and their mycotoxicoses-An overview. Int. J. Food Microb. 2007, 119, 3-10.
    • (2007) Int. J. Food Microb , vol.119 , pp. 3-10
    • Richard, J.L.1
  • 23
    • 11244316554 scopus 로고    scopus 로고
    • Deoxynivalenol: Toxicology and potential effects on humans
    • Pestka, J.J.; Smolinski, A.T. Deoxynivalenol: Toxicology and potential effects on humans. J. Toxicol. Environ. Health. B 2005, 8, 39-69.
    • (2005) J. Toxicol. Environ. Health. B , vol.8 , pp. 39-69
    • Pestka, J.J.1    Smolinski, A.T.2
  • 25
    • 77957184190 scopus 로고
    • Tissue distribution and excretion of radioactivity following administration of 14C-labeled deoxynivalenol to White Leghorn hens
    • Prelusky, D.B.; Hamilton, R.M.; Trenholm, H.L.; Miller, J.D. Tissue distribution and excretion of radioactivity following administration of 14C-labeled deoxynivalenol to White Leghorn hens. Fundam. Appl. Toxicol. 1986, 7, 635-645.
    • (1986) Fundam. Appl. Toxicol , vol.7 , pp. 635-645
    • Prelusky, D.B.1    Hamilton, R.M.2    Trenholm, H.L.3    Miller, J.D.4
  • 26
    • 11244335321 scopus 로고    scopus 로고
    • Toxicokinetic, Tissue Residue, and Metabolic Studies of Deoxynivalenol (Vomitoxin) In Turkeys
    • Master thesis, Simon Fraser University, Vancouver, Canada
    • Gauvreau, H.C. Toxicokinetic, Tissue Residue, and Metabolic Studies of Deoxynivalenol (Vomitoxin) in Turkeys. Master thesis, Simon Fraser University, Vancouver, Canada, 2000.
    • (2000)
    • Gauvreau, H.C.1
  • 27
    • 0026450895 scopus 로고
    • Microbial transformation of deoxynivalenol (vomitoxin)
    • He, P.; Young, L.G.; Forsberg, C. Microbial transformation of deoxynivalenol (vomitoxin). Appl. Environ. Microbiol. 1992, 58, 3857-3863.
    • (1992) Appl. Environ. Microbiol , vol.58 , pp. 3857-3863
    • He, P.1    Young, L.G.2    Forsberg, C.3
  • 28
    • 0024474667 scopus 로고
    • Absorption and elimination of an oral dose of 3H-deoxynivalenol in colostomized and intact chickens
    • Lun, A.K.; Moran, E.T., Jr.; Young, L.G.; McMillan, E.G. Absorption and elimination of an oral dose of 3H-deoxynivalenol in colostomized and intact chickens. Bull. Environ. Contam. Toxicol. 1989, 42, 919-925.
    • (1989) Bull. Environ. Contam. Toxicol , vol.42 , pp. 919-925
    • Lun, A.K.1    Moran Jr., E.T.2    Young, L.G.3    McMillan, E.G.4
  • 29
    • 84857080085 scopus 로고    scopus 로고
    • Genotoxic effects of deoxynivalenol in broiler chickens fed with low protein diets
    • Awad, W.A.; Ghareeb, K.; Dadak, A.; Gille, L.; Staniek, K.; Hess, M.; Böhm, J. Genotoxic effects of deoxynivalenol in broiler chickens fed with low protein diets. Poult. Sci. 2012, 91, 550-555.
    • (2012) Poult. Sci , vol.91 , pp. 550-555
    • Awad, W.A.1    Ghareeb, K.2    Dadak, A.3    Gille, L.4    Staniek, K.5    Hess, M.6    Böhm, J.7
  • 30
    • 18844466478 scopus 로고    scopus 로고
    • Effects of graded levels of Fusarium toxincontaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters
    • Dänicke, S.; Matthes, S.; Halle, I.; Ueberschar, K.H.; Döll, S.; Valenta, H. Effects of graded levels of Fusarium toxincontaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters. Br. Poult. Sci. 2003, 44, 113-126.
    • (2003) Br. Poult. Sci , vol.44 , pp. 113-126
    • Dänicke, S.1    Matthes, S.2    Halle, I.3    Ueberschar, K.H.4    Döll, S.5    Valenta, H.6
  • 31
    • 81555216000 scopus 로고    scopus 로고
    • Effects of increasing dietary concentrations of corn naturally contaminated with deoxynivalenol on broiler and turkey poult performance and response to lipopolysaccharide
    • Xu, L.; Eicher, S.D.; Applegate, T.J. Effects of increasing dietary concentrations of corn naturally contaminated with deoxynivalenol on broiler and turkey poult performance and response to lipopolysaccharide. Poult. Sci. 2011, 90, 2766-2774.
    • (2011) Poult. Sci , vol.90 , pp. 2766-2774
    • Xu, L.1    Eicher, S.D.2    Applegate, T.J.3
  • 32
    • 0024743175 scopus 로고
    • Decreased egg production in commercial laying hens fed zearalenone- and deoxynivalenol-contaminated grain sorghum
    • Branton, S.L.; Deaton, J.W.; Hagler, W.M.; Maslin, W.R., Jr.; Hardin, J.M. Decreased egg production in commercial laying hens fed zearalenone- and deoxynivalenol-contaminated grain sorghum. Avian Dis. 1989, 33, 804-808.
    • (1989) Avian Dis , vol.33 , pp. 804-808
    • Branton, S.L.1    Deaton, J.W.2    Hagler, W.M.3    Maslin Jr., W.R.4    Hardin, J.M.5
  • 34
    • 33847292007 scopus 로고    scopus 로고
    • On the interactions between Fusarium toxin-contaminated wheat and non-starch-polysaccharide hydrolysing enzymes in turkey diets on performance, health and carry-over of deoxynivalenol and zearalenone
    • Dänicke, S.; Valenta, H.; Ueberschär, K.H.; Matthes, S. On the interactions between Fusarium toxin-contaminated wheat and non-starch-polysaccharide hydrolysing enzymes in turkey diets on performance, health and carry-over of deoxynivalenol and zearalenone. Br. Poult. Sci. 2007, 48, 39-48.
    • (2007) Br. Poult. Sci , vol.48 , pp. 39-48
    • Dänicke, S.1    Valenta, H.2    Ueberschär, K.H.3    Matthes, S.4
  • 35
    • 0031067381 scopus 로고    scopus 로고
    • Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and diacetoxyscirpenol or ochratoxin A in turkey poults
    • Kubena, L.F.; Edrington, T.S.; Harvey, R.B.; Phillips, T.D.; Sarr, A.B.; Rottinghaus, G.E. Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and diacetoxyscirpenol or ochratoxin A in turkey poults. Poult. Sci. 1997, 76, 256-264.
    • (1997) Poult. Sci , vol.76 , pp. 256-264
    • Kubena, L.F.1    Edrington, T.S.2    Harvey, R.B.3    Phillips, T.D.4    Sarr, A.B.5    Rottinghaus, G.E.6
  • 36
    • 0031252128 scopus 로고    scopus 로고
    • Moniliformin from Fusarium fujikuroi culture material and deoxynivalenol from naturally contaminated wheat incorporated into diets of broiler chicks
    • Harvey, R.B.; Kubena, L.F.; Rottinghaus, G.E.; Turk, J.R.; Casper, H.H.; Buckley, S.A. Moniliformin from Fusarium fujikuroi culture material and deoxynivalenol from naturally contaminated wheat incorporated into diets of broiler chicks. Avian Dis. 1997, 41, 957-963.
    • (1997) Avian Dis , vol.41 , pp. 957-963
    • Harvey, R.B.1    Kubena, L.F.2    Rottinghaus, G.E.3    Turk, J.R.4    Casper, H.H.5    Buckley, S.A.6
  • 37
    • 0032789668 scopus 로고    scopus 로고
    • Influence of fusariotoxins on growing and slaughtering performance of broilers
    • Leitgeb, R.; Lew, H.; Wetscherek, W.; Böhm, J.; Quinz, A. Influence of fusariotoxins on growing and slaughtering performance of broilers. Aust. J. Agric. Res. 1999, 50, 57-66.
    • (1999) Aust. J. Agric. Res , vol.50 , pp. 57-66
    • Leitgeb, R.1    Lew, H.2    Wetscherek, W.3    Böhm, J.4    Quinz, A.5
  • 38
    • 0036634154 scopus 로고    scopus 로고
    • Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers
    • Swamy, H.V.L.N.; Smith, T.K.; Cotter, P.F.; Boermans, H.J.; Seftons, A.E. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. Poult. Sci. 2002, 81, 966-975.
    • (2002) Poult. Sci , vol.81 , pp. 966-975
    • Swamy, H.V.L.N.1    Smith, T.K.2    Cotter, P.F.3    Boermans, H.J.4    Seftons, A.E.5
  • 39
    • 0347716454 scopus 로고    scopus 로고
    • The impact of low concentrations of aflatoxin, deoxynivalenol or fumonisin in diets on growing pigs and poultry
    • Li, Y.D.; Verstegen, M.W.A.; Gerrits, W.J.J. The impact of low concentrations of aflatoxin, deoxynivalenol or fumonisin in diets on growing pigs and poultry. Nutr. Res. Rev. 2003, 16, 223-239.
    • (2003) Nutr. Res. Rev , vol.16 , pp. 223-239
    • Li, Y.D.1    Verstegen, M.W.A.2    Gerrits, W.J.J.3
  • 40
    • 82255180831 scopus 로고    scopus 로고
    • The impact of the Fusarium mycotoxin deoxynivalenol on the health and performance of broiler chickens
    • Awad, W.A.; Hess, M.; Twaruzek, M.; Grajewski, J.; Kosicki, R.; Böhm, J.; Zentek, J. The impact of the Fusarium mycotoxin deoxynivalenol on the health and performance of broiler chickens. Int. J. Mol. Sci. 2011, 12, 7996-8012.
    • (2011) Int. J. Mol. Sci , vol.12 , pp. 7996-8012
    • Awad, W.A.1    Hess, M.2    Twaruzek, M.3    Grajewski, J.4    Kosicki, R.5    Böhm, J.6    Zentek, J.7
  • 41
    • 79960924960 scopus 로고    scopus 로고
    • A diet naturally contaminated with the Fusarium mycotoxin deoxynivalenol (DON) downregulates gene expression of glucose transporters in the intestine of broiler chickens
    • Awad, W.A.; Vahjen, W.; Aschenbach, J.R.; Zentek, J. A diet naturally contaminated with the Fusarium mycotoxin deoxynivalenol (DON) downregulates gene expression of glucose transporters in the intestine of broiler chickens. Livest. Sci. 2011, 140, 72-79.
    • (2011) Livest. Sci , vol.140 , pp. 72-79
    • Awad, W.A.1    Vahjen, W.2    Aschenbach, J.R.3    Zentek, J.4
  • 42
    • 0345128701 scopus 로고
    • Corn contaminated with deoxynivalenol: Effects on Performance of poultry
    • Keshavarz, K. Corn contaminated with deoxynivalenol: Effects on Performance of poultry. J. Appl. Poult. Res. 1993, 2, 43-50.
    • (1993) J. Appl. Poult. Res , vol.2 , pp. 43-50
    • Keshavarz, K.1
  • 43
    • 20444428380 scopus 로고    scopus 로고
    • Effects of luminal deoxynivalenol and L-proline on electrophysiological parameters in the jejunums of laying hens
    • Awad, W.A.; Rehman, H.; Böhm, J.; Razzazi-Fazeli, E.; Zentek, J. Effects of luminal deoxynivalenol and L-proline on electrophysiological parameters in the jejunums of laying hens. Poult. Sci. 2005, 84, 928-932.
    • (2005) Poult. Sci , vol.84 , pp. 928-932
    • Awad, W.A.1    Rehman, H.2    Böhm, J.3    Razzazi-Fazeli, E.4    Zentek, J.5
  • 44
    • 0031243838 scopus 로고    scopus 로고
    • Na/D-glucose cotransport and SGLT1 expression in hen colon correlates with dietary Na+
    • Bindslev, N.; Hirayama, B.A.; Wright, E.M. Na/D-glucose cotransport and SGLT1 expression in hen colon correlates with dietary Na+. Comp. Biochem. Physiol. A 1997, 118, 219-227.
    • (1997) Comp. Biochem. Physiol. A , vol.118 , pp. 219-227
    • Bindslev, N.1    Hirayama, B.A.2    Wright, E.M.3
  • 45
    • 0033175578 scopus 로고    scopus 로고
    • The individual and combined effects of feeding moniliformin, supplied by Fusarium fujikuroi culture material, and deoxynivalenol in young turkey poults
    • Morris, C.M.; Li, Y.C.; Ledoux, D.R.; Bermudez, A.J.; Rottinghaus, G.E. The individual and combined effects of feeding moniliformin, supplied by Fusarium fujikuroi culture material, and deoxynivalenol in young turkey poults. Poult. Sci. 1999, 78, 1110-1115.
    • (1999) Poult. Sci , vol.78 , pp. 1110-1115
    • Morris, C.M.1    Li, Y.C.2    Ledoux, D.R.3    Bermudez, A.J.4    Rottinghaus, G.E.5
  • 46
    • 85053318909 scopus 로고
    • Biochemical Mechanism of Action of Trichothecene Mycotoxins
    • CRC Press: Boca Raton, FL, USA, Volume
    • Feinberg, B.; Mclaughlin, C.S. Biochemical Mechanism of Action of Trichothecene Mycotoxins. In Trichothecene Mycotoxicosis: Pathophysiologic Effects; Beasley, V.R., Ed.; CRC Press: Boca Raton, FL, USA, 1989; Volume I, pp. 27-35.
    • (1989) Trichothecene Mycotoxicosis: Pathophysiologic Effects , vol.1 , pp. 27-35
    • Feinberg, B.1    McLaughlin, C.S.2
  • 47
    • 2942597779 scopus 로고    scopus 로고
    • Effects of graded levels of Fusarium-toxin-contaminated wheat in Pekin duck diets on performance, health and metabolism of deoxynivalenol and zearalenone
    • Dänicke, S.; Ueberschär, K.H.; Valenta, H.; Matthes, S.; Matthäus, K.; Halle, I. Effects of graded levels of Fusarium-toxin-contaminated wheat in Pekin duck diets on performance, health and metabolism of deoxynivalenol and zearalenone. Br. Poult. Sci. 2004, 45, 264-272.
    • (2004) Br. Poult. Sci , vol.45 , pp. 264-272
    • Dänicke, S.1    Ueberschär, K.H.2    Valenta, H.3    Matthes, S.4    Matthäus, K.5    Halle, I.6
  • 48
    • 3142529204 scopus 로고    scopus 로고
    • Effects of deoxynivalenol and degradation enzyme on growth performance and immune responses in mule ducks
    • Cheng, Y.H.; Chang, M.H.; Lin, Y.A.; Wu, J.F.; Chen, B.J. Effects of deoxynivalenol and degradation enzyme on growth performance and immune responses in mule ducks. J. Anim. Feed Sci. 2004, 13, 275-287.
    • (2004) J. Anim. Feed Sci , vol.13 , pp. 275-287
    • Cheng, Y.H.1    Chang, M.H.2    Lin, Y.A.3    Wu, J.F.4    Chen, B.J.5
  • 50
    • 0022730663 scopus 로고
    • Effects of feeding hens a high level of vomitoxin-contaminated corn on performance and tissues residues
    • Lun, A.K.; Young, L.G.; Moran, J.E.T.; Hunter, D.B.; Rodriguez, J.P. Effects of feeding hens a high level of vomitoxin-contaminated corn on performance and tissues residues. Poult. Sci. 1986, 65, 1095-1099.
    • (1986) Poult. Sci , vol.65 , pp. 1095-1099
    • Lun, A.K.1    Young, L.G.2    Moran, J.E.T.3    Hunter, D.B.4    Rodriguez, J.P.5
  • 52
    • 53349156337 scopus 로고    scopus 로고
    • An integrated approach to understanding gut function and gut health of chickens
    • Hughes, R.J. An integrated approach to understanding gut function and gut health of chickens. Asia Pac. J. Clin. Nutri. 2005, 14, S27.
    • (2005) Asia Pac. J. Clin. Nutri , vol.14
    • Hughes, R.J.1
  • 53
    • 24944587966 scopus 로고    scopus 로고
    • The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell-derived innate immune response
    • Bouhet, S.; Oswald, I.P. The effects of mycotoxins, fungal food contaminants, on the intestinal epithelial cell-derived innate immune response. Vet. Immunol. Immunopathol. 2005, 108, 199-209.
    • (2005) Vet. Immunol. Immunopathol , vol.108 , pp. 199-209
    • Bouhet, S.1    Oswald, I.P.2
  • 54
    • 0036714478 scopus 로고    scopus 로고
    • The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells
    • Maresca, M.; Mahfoud, R.; Garmy, N.; Fantini, J. The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. J. Nutr. 2002, 132, 2723-2731.
    • (2002) J. Nutr , vol.132 , pp. 2723-2731
    • Maresca, M.1    Mahfoud, R.2    Garmy, N.3    Fantini, J.4
  • 56
    • 0025302044 scopus 로고
    • Alteration of immune function following dietary mycotoxin exposure
    • Pestka, J.J.; Bondy, G.S. Alteration of immune function following dietary mycotoxin exposure. Can. J. Physiol. Pharmacol. 1990, 68, 1009-1016.
    • (1990) Can. J. Physiol. Pharmacol , vol.68 , pp. 1009-1016
    • Pestka, J.J.1    Bondy, G.S.2
  • 57
    • 0027964836 scopus 로고
    • Elevated gene expression and production of interleukins 2, 4, 5 and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma
    • Dong, W.; Azcona Olivera, J.I.; Brooks, K.H.; Linz, J.E.; Pestka, J.J. Elevated gene expression and production of interleukins 2, 4, 5 and 6 during exposure to vomitoxin (deoxynivalenol) and cycloheximide in the EL-4 thymoma. Toxicol. Appl. Pharmacol. 1994, 127, 282-290.
    • (1994) Toxicol. Appl. Pharmacol , vol.127 , pp. 282-290
    • Dong, W.1    Azcona Olivera, J.I.2    Brooks, K.H.3    Linz, J.E.4    Pestka, J.J.5
  • 58
    • 0028041261 scopus 로고
    • In vitro effects of vomitoxin (Deoxynivalenol) on lymphocyte function: Enhanced interleukin production and help for IgA secretion
    • Warner, R.L.; Brooks, K.; Pestka, J.J. In vitro effects of vomitoxin (Deoxynivalenol) on lymphocyte function: Enhanced interleukin production and help for IgA secretion. Food Chem. Toxicol. 1994, 32, 617-625.
    • (1994) Food Chem. Toxicol , vol.32 , pp. 617-625
    • Warner, R.L.1    Brooks, K.2    Pestka, J.J.3
  • 60
    • 84857978814 scopus 로고    scopus 로고
    • Deoxynivalenol as a contaminant of broiler feed: Effects on bird performance and response to common vaccines
    • Yunus, A.W.; Ghareeb, K.; Twaruzek, M.; Grajewski, J.; Böhm, J. Deoxynivalenol as a contaminant of broiler feed: Effects on bird performance and response to common vaccines. Poult. Sci. 2012, 91, 844-851.
    • (2012) Poult. Sci , vol.91 , pp. 844-851
    • Yunus, A.W.1    Ghareeb, K.2    Twaruzek, M.3    Grajewski, J.4    Böhm, J.5
  • 61
    • 33748536677 scopus 로고    scopus 로고
    • Effects of feeding grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of broiler breeders
    • Yegani, M.; Smith, T.K.; Leeson, S.; Boermans, H.J. Effects of feeding grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of broiler breeders. Poult. Sci. 2006, 85, 1541-1549.
    • (2006) Poult. Sci , vol.85 , pp. 1541-1549
    • Yegani, M.1    Smith, T.K.2    Leeson, S.3    Boermans, H.J.4
  • 62
    • 0024460931 scopus 로고
    • Dysregulation of IgA production and IgA nephropathy induced by the trichothecene vomitoxin
    • Pestka, J.J.; Moorman, M.A.; Warner, R.L. Dysregulation of IgA production and IgA nephropathy induced by the trichothecene vomitoxin. Food Chem. Toxicol. 1989, 27, 361-368.
    • (1989) Food Chem. Toxicol , vol.27 , pp. 361-368
    • Pestka, J.J.1    Moorman, M.A.2    Warner, R.L.3
  • 63
    • 77957176144 scopus 로고
    • Quantitative assessment of mesangial immunoglobulin A (IgA) accumulation, elevated circulating IgA immune complexes, and hematuria during vomitoxin-induced IgA nephropathy
    • Dong, W.; Sell, J.E.; Pestka, J.J. Quantitative assessment of mesangial immunoglobulin A (IgA) accumulation, elevated circulating IgA immune complexes, and hematuria during vomitoxin-induced IgA nephropathy. Fundam. Appl. Toxicol. 1991, 17, 197-207.
    • (1991) Fundam. Appl. Toxicol , vol.17 , pp. 197-207
    • Dong, W.1    Sell, J.E.2    Pestka, J.J.3
  • 64
    • 0027537375 scopus 로고
    • Persistent dysregulation of IgA production and IgA nephropathy in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol)
    • Dong, W.; Pestka, J.J. Persistent dysregulation of IgA production and IgA nephropathy in the B6C3F1 mouse following withdrawal of dietary vomitoxin (deoxynivalenol). Fundam. Appl. Toxicol. 1993, 20, 38-47.
    • (1993) Fundam. Appl. Toxicol , vol.20 , pp. 38-47
    • Dong, W.1    Pestka, J.J.2
  • 65
    • 0025761196 scopus 로고
    • Dietary exposure to the trichothecene vomitoxin (Deoxynivalenol) stimulates terminal differentiation of Peyer's patch B cells to IgA secreting plasma cells
    • Bondy, G.S.; Pestka, J.J. Dietary exposure to the trichothecene vomitoxin (Deoxynivalenol) stimulates terminal differentiation of Peyer's patch B cells to IgA secreting plasma cells. Toxicol. Appl. Pharmacol. 1991, 108, 520-530.
    • (1991) Toxicol. Appl. Pharmacol , vol.108 , pp. 520-530
    • Bondy, G.S.1    Pestka, J.J.2
  • 66
    • 0028343285 scopus 로고
    • Polyclonal autoreactive IgA increase and mesangial deposition during vomitoxin induced IgA nephropahty in the BALB/c mouse
    • Rasooly, L.; Pestka, J.J. Polyclonal autoreactive IgA increase and mesangial deposition during vomitoxin induced IgA nephropahty in the BALB/c mouse. Food Chem. Toxicol. 1994, 32, 329-336.
    • (1994) Food Chem. Toxicol , vol.32 , pp. 329-336
    • Rasooly, L.1    Pestka, J.J.2
  • 67
    • 33645740194 scopus 로고    scopus 로고
    • Effects of feed-borne Fusarium mycotoxins on hematology and immunology of laying hens
    • Chowdhury, S.R.; Smith, T.K.; Boermans, H.J.; Woodward, B. Effects of feed-borne Fusarium mycotoxins on hematology and immunology of laying hens. Poult. Sci. 2005, 84, 1841-1850.
    • (2005) Poult. Sci , vol.84 , pp. 1841-1850
    • Chowdhury, S.R.1    Smith, T.K.2    Boermans, H.J.3    Woodward, B.4
  • 68
    • 84866502728 scopus 로고    scopus 로고
    • Effects of feed-borne Fusarium mycotoxins with or without yeast cell wall adsorbent on organ weight, serum biochemistry, and immunological parameters of broiler chickens
    • Li, Z.; Yang, Z.B.; Yang, W.R.; Wang, S.J.; Jiang, S.Z.; Wu, Y.B. Effects of feed-borne Fusarium mycotoxins with or without yeast cell wall adsorbent on organ weight, serum biochemistry, and immunological parameters of broiler chickens. Poult. Sci. 2012, 91, 2487-2495.
    • (2012) Poult. Sci , vol.91 , pp. 2487-2495
    • Li, Z.1    Yang, Z.B.2    Yang, W.R.3    Wang, S.J.4    Jiang, S.Z.5    Wu, Y.B.6
  • 69
    • 0028608991 scopus 로고
    • Flow cytometric analysis of the effects of in vitro exposure to vomitoxin (deoxynivalenol) on apoptosis in murine T B and IgA+ cells
    • Pestka, J.J.; Yan, D.; King, L.E. Flow cytometric analysis of the effects of in vitro exposure to vomitoxin (deoxynivalenol) on apoptosis in murine T B and IgA+ cells. Food Chem. Toxicol. 1994, 32, 1125-1136.
    • (1994) Food Chem. Toxicol , vol.32 , pp. 1125-1136
    • Pestka, J.J.1    Yan, D.2    King, L.E.3
  • 70
    • 0032134901 scopus 로고    scopus 로고
    • Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice
    • Islam, Z.; Nagase, M.; Ota, A.; Ueda, S.; Yoshizawa, T.; Sakato, N. Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice. Biosci. Biotechnol. Biochem. 1998, 62, 1492-1497.
    • (1998) Biosci. Biotechnol. Biochem , vol.62 , pp. 1492-1497
    • Islam, Z.1    Nagase, M.2    Ota, A.3    Ueda, S.4    Yoshizawa, T.5    Sakato, N.6
  • 71
    • 33750721383 scopus 로고    scopus 로고
    • The role of dietary nucleotides in reduction of DNA damage induced by T-2 toxin and deoxynivalenol in chicken leukocytes
    • Frankic, T.; Pajk, T.; Rezar, V.; Levart, A.; Salobir, J. The role of dietary nucleotides in reduction of DNA damage induced by T-2 toxin and deoxynivalenol in chicken leukocytes. Food Chem. Toxicol. 2006, 44, 1838-1844.
    • (2006) Food Chem. Toxicol , vol.44 , pp. 1838-1844
    • Frankic, T.1    Pajk, T.2    Rezar, V.3    Levart, A.4    Salobir, J.5
  • 72
    • 0030789866 scopus 로고    scopus 로고
    • Potential role for IL-5 and IL-6 in enhanced IgA secretion by Peyer's patch cells isolated from mice acutely exposed to vomitoxin
    • Yan, D.; Zhou, H.R.; Brooks, K.H.; Pestka, J.J. Potential role for IL-5 and IL-6 in enhanced IgA secretion by Peyer's patch cells isolated from mice acutely exposed to vomitoxin. Toxicology 1997, 122, 145-158.
    • (1997) Toxicology , vol.122 , pp. 145-158
    • Yan, D.1    Zhou, H.R.2    Brooks, K.H.3    Pestka, J.J.4
  • 73
    • 0030175769 scopus 로고    scopus 로고
    • Vomitoxin mediated IL2, IL4 and IL5 superinduction in murine CD4+ T cells stimulated with phorbol ester calcium ionophore: Relation to kinetics of poliferation
    • Ouyang, Y.L.; Azcona Olivera, J.I.; Murtha, J.M.; Pestka, J.J. Vomitoxin mediated IL2, IL4 and IL5 superinduction in murine CD4+ T cells stimulated with phorbol ester calcium ionophore: Relation to kinetics of poliferation. Toxicol. Appl. Pharmacol. 1996, 138, 324-334.
    • (1996) Toxicol. Appl. Pharmacol , vol.138 , pp. 324-334
    • Ouyang, Y.L.1    Azcona Olivera, J.I.2    Murtha, J.M.3    Pestka, J.J.4
  • 74
    • 0023067941 scopus 로고
    • The in vitro effects of trichothecenes on the immune system
    • Miller, K.; Atkinson, H.A. The in vitro effects of trichothecenes on the immune system. Arch. Toxicol. 1987, 11, 321-324.
    • (1987) Arch. Toxicol , vol.11 , pp. 321-324
    • Miller, K.1    Atkinson, H.A.2
  • 75
    • 33744516646 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes
    • Islam, Z.; Gray, J.S.; Pestka, J.J. p38 mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes. Toxicol. Appl. Pharmacol. 2005, 213, 235-244.
    • (2005) Toxicol. Appl. Pharmacol , vol.213 , pp. 235-244
    • Islam, Z.1    Gray, J.S.2    Pestka, J.J.3
  • 76
    • 0031595740 scopus 로고    scopus 로고
    • Modulation of IL-1, IL-6 and TNF- secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line
    • Wong, S.S.; Zhou, H.R.; Marin-Martinez, M.L.; Brooks, K.; Pestka, J.J. Modulation of IL-1, IL-6 and TNF- secretion and mRNA expression by the trichothecene vomitoxin in the RAW 264.7 murine macrophage cell line. Food Chem. Toxicol. 1998, 36, 409-419.
    • (1998) Food Chem. Toxicol , vol.36 , pp. 409-419
    • Wong, S.S.1    Zhou, H.R.2    Marin-Martinez, M.L.3    Brooks, K.4    Pestka, J.J.5
  • 77
    • 0029073670 scopus 로고
    • Effects on vomitoxin (Deoxynivalenol) and cyclohexamide on IL-2, 4, 5 and 6 secretion and mRNA levels in murine CD4+ cells
    • Azcona-Olivera, J.I.; Ouyang, Y.L.; Warner, R.L.; Linz, J.E.; Pestka, J.J. Effects on vomitoxin (Deoxynivalenol) and cyclohexamide on IL-2, 4, 5 and 6 secretion and mRNA levels in murine CD4+ cells. Food Chem. Toxicol. 1995, 33, 433-441.
    • (1995) Food Chem. Toxicol , vol.33 , pp. 433-441
    • Azcona-Olivera, J.I.1    Ouyang, Y.L.2    Warner, R.L.3    Linz, J.E.4    Pestka, J.J.5
  • 78
    • 0031172809 scopus 로고    scopus 로고
    • Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (Deoxynivalenol): Dose response and time course
    • Zhou, H.R.; Yan, D.; Pestka, J.J. Differential cytokine mRNA expression in mice after oral exposure to the trichothecene vomitoxin (Deoxynivalenol): Dose response and time course. Toxicol. Appl. Pharmacol. 1997, 144, 294-305.
    • (1997) Toxicol. Appl. Pharmacol , vol.144 , pp. 294-305
    • Zhou, H.R.1    Yan, D.2    Pestka, J.J.3
  • 79
    • 84866502728 scopus 로고    scopus 로고
    • Effects of feed-borne Fusarium mycotoxins with or without yeast cell wall adsorbent on organ weight, serum biochemistry, and immunological parameters of broiler chickens
    • Li, Z.; Yang, Z.B.; Yang, W.R.; Wang, S.J.; Jiang, S.Z.; Wu, Y.B. Effects of feed-borne Fusarium mycotoxins with or without yeast cell wall adsorbent on organ weight, serum biochemistry, and immunological parameters of broiler chickens. Poult. Sci. 2012, 91, 2487-2495.
    • (2012) Poult. Sci , vol.91 , pp. 2487-2495
    • Li, Z.1    Yang, Z.B.2    Yang, W.R.3    Wang, S.J.4    Jiang, S.Z.5    Wu, Y.B.6
  • 80
    • 58249089683 scopus 로고    scopus 로고
    • Immunomodulatory effects of feed-borne Fusarium mycotoxins in chickens infected with Coccidia
    • Girgis, G.N.; Shayan, S.; Barta, J.R.; Boermans, H.J.; Smith, T.K. Immunomodulatory effects of feed-borne Fusarium mycotoxins in chickens infected with Coccidia. Exp. Biol. Med. 2008, 233, 1411-1420.
    • (2008) Exp. Biol. Med , vol.233 , pp. 1411-1420
    • Girgis, G.N.1    Shayan, S.2    Barta, J.R.3    Boermans, H.J.4    Smith, T.K.5


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