Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens

Poultry Science

Volumn 83, Issue 4, 2004, Pages 533-543

  Swamy, H V L N ^a   Smith, T K ^a   Karrow, N A ^a   Boermans, H J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

Chicken; Deoxynivalenol; Fusaric acid; Fusarium mycotoxin; Immunotoxicity

Indexed keywords

AVES; FUNGI; FUSARIUM; GALLUS GALLUS;

15 ACETYLVOMITOXIN; 15-ACETYLDEOXYNIVALENOL; MYCOTOXIN; TRICHOTHECENE DERIVATIVE; VOMITOXIN; ZEARALENONE;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; BIRD DISEASE; CALORIC INTAKE; CHICKEN; CONTACT DERMATITIS; DRUG EFFECT; FOOD CONTAMINATION; FUSARIUM; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE; MALE; MEAT; MICROBIOLOGY; ORGAN SIZE; WEIGHT GAIN;

ANIMAL FEED; ANIMALS; CHICKENS; DERMATITIS, CONTACT; ENERGY INTAKE; FOOD CONTAMINATION; FUSARIUM; IMMUNOPHENOTYPING; LYMPHOCYTES; MALE; MEAT; MYCOTOXINS; ORGAN SIZE; POULTRY DISEASES; TRICHOTHECENES; WEIGHT GAIN; ZEARALENONE;

EID: 4043138556     PISSN: 00325791     EISSN: None     Source Type: Journal    
DOI: 10.1093/ps/83.4.533     Document Type: Article

References (39)

1. Association of Official Analytical Chemists. 1980. Official methods of analysis. 13th ed. AOAC, Washington DC.
2. Bacon, C. W., and H. L. Marks. 1976. Growth of broilers and quail fed Fusarium (Gibberella zeae)-infected corn and zearalenone. Poult. Sci. 55:1531-1535.
3. Bianchi, A. T. J., H. W. M. Moonen-Leusen, P. J. van der Heijden, and B. A. Bokhout. 1995. The use of a double antibody sandwich ELISA and monoclonal antibodies for the assessment of porcine IgM, IgG and IgA concentrations. Vet. Immunol. Immunopathol. 44:309-317.
4. Bondy, G. S., and J. J. Pestka. 2000. Immunomodulation by fungal toxins. J. Toxicol. Environ. Health B. Crit. Rev. 3:109-143.
5. Chu, Q., W. Weidong, and E. B. Smalley. 1993. Decreased cell mediated immunity and lack of skeletal problems in broiler chickens consuming diets amended with fusaric acid. Avian Dis. 37:863-867.
6. Davis, N. D., J. W. Dickens, R. L. Freie, P. B. Hamilton, O. L. Shotwell, T. D. Wyllie, and J. F. Fulkerson. 1980. Protocols for surveys, sampling, post-collection handling, and analysis of grain samples involved in mycotoxin problems. J. Assoc. Off. Anal. Chem. 63:95-102.
7. Furesz, S. E., B. A. Mallard, J. T. Bosse, S. Rosendal, B. N. Wilkie, and J. I. Macinnes. 1997. Antibody- and cell-mediated immune responses of Actinobacillus pleuropneumoniae-infected and bacterin-vaccinated pigs. Infect. Immun. 65:358-365.
8. Hamilton, P. B. 1978. Fallacies in our understanding of mycotoxins. J. Food Prot. 41:404-408.
9. Harvey, R. B., L. F. Kubena, W. E. Huff, M. H. Elissalde, and T. D. Phillips. 1991. Hematologic and immunologic toxicity of deoxynivalenol (DON)-contaminated diets to growing chickens. Bull. Environ. Contam. Toxicol. 46:410-416.
10. Holsapple, M. P. 1995. The plaque-forming cell response in immunotoxicology: An approach to monitoring the primary effector function of B lymphocytes. Page 71 in Methods in Immunotoxicology. G. R. Burleson, J. H. Dean, and A. E. Munson, ed. Wiley-Liss, New York.
11. Huff, W. E., L. F. Kubena, R. B. Harvey, W. M. Hagler Jr., S. P. Swanson, T. D. Phillips, and C. R. Creger. 1986. Individual and combined effects of aflatoxin and deoxynivalenol (DON, vomitoxin) in broiler chickens. Poult. Sci. 65:1291-1298.
12. Hulan, H. W., and F. G. Proudfoot. 1982. Effects of feeding vomitoxin contaminated wheat on the performance of broiler chickens. Poult. Sci. 61:1653-1659.
13. Kubena, L. F., T. S. Edrington, R. B. Harvey, S. A. Buckley, T. D. Phillips, G. E. Rottinghaus, and H. H. Casper. 1997. Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. Poult. Sci. 76:1239-1247.
14. Kubena, L. F., W. E. Huff, R. B. Harvey, D. E. Corrier, T. D. Phillips, and C. R. Creger. 1988. Influence of ochratoxin A and deoxynivalenol on growing broiler chicks. Poult. Sci. 67:253-260.
15. Kubena, L. F., W. E. Huff, R. B. Harvey, T. D. Phillips, and G. E. Rottinghaus. 1989a. Individual and combined toxicity of deoxynivalenol and T-2 toxin in broiler chicks. Poult. Sci. 68:622-626.
16. Kubena, L. F., S. P. Swanson, R. B. Harvey, O. J. Fletcher, L. D. Rowe, and T. D. Phillips. 1985. Effects of feeding deoxynivalenol (vomitoxin)- contaminated wheat to growing chicks. Poult. Sci. 64:1649-1655.
17. Leeson, S., and J. D. Summers. 1997. Commercial Poultry Nutrition. 2nd ed. University Books, Guelph, ON, Canada.
18. Lewis, J. G. 1995. Introduction to the mononuclear phagocyte system. Page 3 in Methods in Immunotoxicology. G. R. Burleson, J. H. Dean, and A. E. Munson, ed. Wiley-Liss, New York.
19. Lombaert, G. A. 2002. Methods for the determination of deoxynivalenol and other trichothecenes in foods. Page 141 in Mycotoxins and Food Safety. Advances in Experimental Medicine and Biology. J. W. Devries, M. W. Trucksess, and L. S. Jackson, ed. Kluwer Academic/Plenum, New York.
20. Matsui, Y., and M. Watanabe. 1988. Quantitative analysis of fusaric acid in the cultural filtrate and soybean plants inoculated with Fusarium oxysporum var. redolens. J. Rakuno Gakuen Univ. Nat. Sci. 13:159-167.
21. Miller, K., and C. Meredith. 1999. Immunotoxicology. Pages 997-1015 in General and Applied Toxicology. 2nd ed. B. Ballantyne, C. M. Tymothy, and T. L. M. Syversen, ed. Grove's Dictionaries, New York.
22. Morris, C. M., Y. C. Li, D. R. Ledoux, A. J. Bermudez, and G. E. Rottinghaus. 1999. The individual and combined effects of feeding moniliformin, supplied by Fusarium fujikuroi culture material, and deoxynivalenol in young turkey poults. Poult. Sci. 78:1110-1115.
23. Ochsenbein, A. F., and R. M. Zinkernagel. 2000. Natural antibodies and complement link innate and acquired immunity. Immunol. Today 21:624-630.
24. Pestka, J. J., W. Dong, R. L. Warner, L. Rasooly, G. S. Bondy, and K. H. Brooks. 1990. Elevated membrane IgA+ and CD4+ (T helper) populations in murine Peyer's patch and splenic lymphocytes during dietary administration of the trichothecene vomitoxin (deoxynivalenol). Food Chem. Toxicol. 28:409-420.
25. Porter, J. K., C. W. Bacon, E. M. Wray, and W. M. Hagler, Jr. 1995. Fusaric acid in Fusarium moniliforme cultures, corn, and feeds toxic to livestock and the neurochemical effects in the brain and pineal gland of rats. Nat. Toxins 3:91-100.
26. Prescott, C. A., B. N. Wilkie, B. Hunter, and R. J. Julian. 1982. Influence of a purified grade of pentachlorphenol on the immune response of chickens. Am. J. Vet. Res. 43:481-487.
27. Rotter, B. A., B. K. Thompson, M. Lessard, H. L. Trenholm, and H. Tryphonas. 1994. Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. Fundam. Appl. Toxicol. 23:117-124.
28. Rotter, R. G., B. K. Thompson, H. L. Trenholm, D. B. Prelusky, K. E. Hartin, and J. D. Miller. 1992. A preliminary examination of potential interactions between deoxynivalenol (DON) and other selected Fusarium metabolites in growing pigs. Can. J. Anim. Sci. 72:107-116.
29. SAS Institute. 2000. SAS User's Guide: Statistics. Version 8 ed. SAS Institute Inc., Cary, NC.
30. Savage, T. F., P. F. Cotter, and E. I. Zakrzewska. 1996. The effect of feeding mannan oligosaccharide on immunoglobulins, plasma IgG and IgA, of Wrolstad MW male turkeys. Poult. Sci. 75(Suppl. 1):143. (Abstr.)
31. Smialowicz, R. J. 1995. In vitro lymphocyte proliferation assays: the mitogen-stimulated response and the mixed lymphocyte reaction in immunotoxicology testing. Page 197 in Methods in Immunotoxicology. G. R. Burleson, J. H. Dean, and A. E. Munson, ed. Wiley-Liss, New York.
32. Smith, T. K., E. G. McMillan, and J. B. Castillo. 1997. Effect of feeding blends of Fusarium mycotoxin-contaminated grains containing deoxynivalenol and fusaric acid on growth and feed consumption of immature swine. J. Anim. Sci. 75:2184-2191.
33. Smith, T. K., and M. G. Sousadias. 1993. Fusaric acid content of swine feedstuffs. J. Agric. Food Chem. 41:2296-2298.
34. Spring, P., K. A. Wenk, K. A. Dawson, and K. E. Newman. 2000. Effect of mannanoligosaccharide on different cecal parameters and on cecal concentration of enteric bacteria in challenged broiler chicks. Poult. Sci. 79:205-211.
35. Swamy, H. V. L. N., T. K. Smith, P. F. Cotter, H. J. Boermans, and A. E. Sefton. 2002a. Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism in broilers. Poult. Sci. 81:966-975.
36. Swamy, H. V. L. N., T. K. Smith, E. J. MacDonald, H. J. Boermans, and E. J. Squires. 2002b. Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on swine performance, brain regional neurochemistry and serum chemistry and the efficacy of a polymeric glucomannan mycotoxin adsorbent. J. Anim. Sci. 80:3257-3267.
37. Temple, L., L. Butterworth, T. T. Kawabata, A. E. Munson, and K. L. White Jr. 1995. ELISA to measure SRBC-specific serum IgM: Method and data evaluation. Page 137 in Methods in Immunotoxicology. G. R. Burleson, J. H. Dean, and A. E. Munson, ed. Wiley-Liss, New York.
38. Tryphonas, H., L. O. Grady, D. L. Arnold, F. McGuire, K. Karpinski, and Vesonder. R. F. 1984. Effect of deoxynivalenol (vomitoxin) on the humoral immunity of mice. Toxicol. Lett. 23:17-24.
39. Windel, C. E. 2000. Economic and social impacts of Fusarium head blight: Changing farms and rural communities in the northern Great Plains. Phytopathology 90:17-21.