-
1
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura, H., Nose, M., Hiai, H., Minato, N., and Honjo, T. (1999) Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11, 141-151
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
2
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
Nishimura, H., Okazaki, T., Tanaka, Y., Nakatani, K., Hara, M., Matsumori, A., Sasayama, S., Mizoguchi, A., Hiai, H., Minato, N., and Honjo, T. (2001) Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science 291, 319-322
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
Nakatani, K.4
Hara, M.5
Matsumori, A.6
Sasayama, S.7
Mizoguchi, A.8
Hiai, H.9
Minato, N.10
Honjo, T.11
-
3
-
-
4043070746
-
Association of PDCD1 with susceptibility to systemic lupus erythematosus. Evidence of population-specific effects
-
Ferreiros-Vidal, I., Gomez-Reino, J. J., Barros, F., Carracedo, A., Carreira, P., Gonzalez-Escribano, F., Liz, M., Martin, J., Ordi, J., Vicario, J. L., and Gonzalez, A. (2004) Association of PDCD1 with susceptibility to systemic lupus erythematosus. Evidence of population-specific effects. Arthritis Rheum. 50, 2590-2597
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 2590-2597
-
-
Ferreiros-Vidal, I.1
Gomez-Reino, J.J.2
Barros, F.3
Carracedo, A.4
Carreira, P.5
Gonzalez-Escribano, F.6
Liz, M.7
Martin, J.8
Ordi, J.9
Vicario, J.L.10
Gonzalez, A.11
-
4
-
-
30744431930
-
PDCD1. A tissue-specific susceptibility locus for inherited inflammatory disorders
-
James, E. S., Harney, S., Wordsworth, B. P., Cookson, W. O., Davis, S. J., and Moffatt, M. F. (2005) PDCD1. A tissue-specific susceptibility locus for inherited inflammatory disorders. Genes Immun. 6, 430-437
-
(2005)
Genes Immun.
, vol.6
, pp. 430-437
-
-
James, E.S.1
Harney, S.2
Wordsworth, B.P.3
Cookson, W.O.4
Davis, S.J.5
Moffatt, M.F.6
-
5
-
-
17244383354
-
A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese
-
Kong, E. K., Prokunina-Olsson, L., Wong, W. H., Lau, C. S., Chan, T. M., Alarcón-Riquelme, M., and Lau, Y. L. (2005) A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese. Arthritis Rheum. 52, 1058-1062
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 1058-1062
-
-
Kong, E.K.1
Prokunina-Olsson, L.2
Wong, W.H.3
Lau, C.S.4
Chan, T.M.5
Alarcón-Riquelme, M.6
Lau, Y.L.7
-
6
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber, D. L., Wherry, E. J., Masopust, D., Zhu, B., Allison, J. P., Sharpe, A. H., Freeman, G. J., and Ahmed, R. (2006) Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439, 682-687
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
7
-
-
34547931898
-
+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection
-
+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection. Blood 110, 928-936
-
(2007)
Blood
, vol.110
, pp. 928-936
-
-
Petrovas, C.1
Price, D.A.2
Mattapallil, J.3
Ambrozak, D.R.4
Geldmacher, C.5
Cecchinato, V.6
Vaccari, M.7
Tryniszewska, E.8
Gostick, E.9
Roederer, M.10
Douek, D.C.11
Morgan, S.H.12
Davis, S.J.13
Franchini, G.14
Koup, R.A.15
-
8
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day, C. L., Kaufmann, D. E., Kiepiela, P., Brown, J. A., Moodley, E. S., Reddy, S., Mackey, E. W., Miller, J. D., Leslie, A. J., DePierres, C., Mncube, Z., Duraiswamy, J., Zhu, B., Eichbaum, Q., Altfeld, M., Wherry, E. J., Coovadia, H. M., Goulder, P. J., Klenerman, P., Ahmed, R., Freeman, G. J., and Walker, B. D. (2006) PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443, 350-354
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
9
-
-
33947407689
-
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression
-
Radziewicz, H., Ibegbu, C. C., Fernandez, M. L., Workowski, K. A., Obideen, K., Wehbi, M., Hanson, H. L., Steinberg, J. P., Masopust, D., Wherry, E. J., Altman, J. D., Rouse, B. T., Freeman, G. J., Ahmed, R., and Grakoui, A. (2007) Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. J. Virol. 81, 2545-2553
-
(2007)
J. Virol.
, vol.81
, pp. 2545-2553
-
-
Radziewicz, H.1
Ibegbu, C.C.2
Fernandez, M.L.3
Workowski, K.A.4
Obideen, K.5
Wehbi, M.6
Hanson, H.L.7
Steinberg, J.P.8
Masopust, D.9
Wherry, E.J.10
Altman, J.D.11
Rouse, B.T.12
Freeman, G.J.13
Ahmed, R.14
Grakoui, A.15
-
10
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
-
Urbani, S., Amadei, B., Tola, D., Massari, M., Schivazappa, S., Missale, G., and Ferrari, C. (2006) PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion. J. Virol. 80, 11398-11403
-
(2006)
J. Virol.
, vol.80
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
Massari, M.4
Schivazappa, S.5
Missale, G.6
Ferrari, C.7
-
11
-
-
40149094779
-
+ T cells during acute HCV infection, irrespective of clinical outcome
-
+ T cells during acute HCV infection, irrespective of clinical outcome. J. Virol. 82, 3154-3160
-
(2008)
J. Virol.
, vol.82
, pp. 3154-3160
-
-
Kasprowicz, V.1
Schulze Zur Wiesch, J.2
Kuntzen, T.3
Nolan, B.E.4
Longworth, S.5
Berical, A.6
Blum, J.7
McMahon, C.8
Reyor, L.L.9
Elias, N.10
Kwok, W.W.11
McGovern, B.G.12
Freeman, G.13
Chung, R.T.14
Klenerman, P.15
Lewis-Ximenez, L.16
Walker, B.D.17
Allen, T.M.18
Kim, A.Y.19
Lauer, G.M.20
more..
-
12
-
-
73949088551
-
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
-
Francisco, L. M., Salinas, V. H., Brown, K. E., Vanguri, V. K., Freeman, G. J., Kuchroo, V. K., and Sharpe, A. H. (2009) PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J. Exp. Med. 206, 3015-3029
-
(2009)
J. Exp. Med.
, vol.206
, pp. 3015-3029
-
-
Francisco, L.M.1
Salinas, V.H.2
Brown, K.E.3
Vanguri, V.K.4
Freeman, G.J.5
Kuchroo, V.K.6
Sharpe, A.H.7
-
13
-
-
84859158384
-
Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity
-
Topalian, S. L., Drake, C. G., and Pardoll, D. M. (2012) Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity. Curr. Opin. Immunol. 24, 207-212
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
14
-
-
84864324543
-
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
-
Yokosuka, T., Takamatsu, M., Kobayashi-Imanishi, W., Hashimoto-Tane, A., Azuma, M., and Saito, T. (2012) Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J. Exp. Med. 209, 1201-1217
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1201-1217
-
-
Yokosuka, T.1
Takamatsu, M.2
Kobayashi-Imanishi, W.3
Hashimoto-Tane, A.4
Azuma, M.5
Saito, T.6
-
15
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir, M. E., Butte, M. J., Freeman, G. J., and Sharpe, A. H. (2008) PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26, 677-704
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
16
-
-
0032736029
-
B7-H1, a third member of the B7 family, costimulates T-cell proliferation and interleukin-10 secretion
-
Dong, H., Zhu, G., Tamada, K., and Chen, L. (1999) B7-H1, a third member of the B7 family, costimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5, 1365-1369
-
(1999)
Nat. Med.
, vol.5
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
17
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman, G. J., Long, A. J., Iwai, Y., Bourque, K., Chernova, T., Nishimura, H., Fitz, L. J., Malenkovich, N., Okazaki, T., Byrne, M. C., Horton, H. F., Fouser, L., Carter, L., Ling, V., Bowman, M. R., Carreno, B. M., Collins, M., Wood, C. R., and Honjo, T. (2000) Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192, 1027-1034
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
18
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman, Y., Wood, C. R., Chernova, T., Chaudhary, D., Borde, M., Chernova, I., Iwai, Y., Long, A. J., Brown, J. A., Nunes, R., Greenfield, E. A., Bourque, K., Boussiotis, V. A., Carter, L. L., Carreno, B. M., Malenkovich, N., Nishimura, H., Okazaki, T., Honjo, T., Sharpe, A. H., and Freeman, G. J. (2001) PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat. Immunol. 2, 261-268
-
(2001)
Nat. Immunol.
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
Greenfield, E.A.11
Bourque, K.12
Boussiotis, V.A.13
Carter, L.L.14
Carreno, B.M.15
Malenkovich, N.16
Nishimura, H.17
Okazaki, T.18
Honjo, T.19
Sharpe, A.H.20
Freeman, G.J.21
more..
-
19
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
Tseng, S. Y., Otsuji, M., Gorski, K., Huang, X., Slansky, J. E., Pai, S. I., Shalabi, A., Shin, T., Pardoll, D. M., and Tsuchiya, H. (2001) B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193, 839-846
-
(2001)
J. Exp. Med.
, vol.193
, pp. 839-846
-
-
Tseng, S.Y.1
Otsuji, M.2
Gorski, K.3
Huang, X.4
Slansky, J.E.5
Pai, S.I.6
Shalabi, A.7
Shin, T.8
Pardoll, D.M.9
Tsuchiya, H.10
-
20
-
-
65349118810
-
PD-1 signalling in primary T cells
-
Riley, J. L. (2009) PD-1 signalling in primary T cells. Immunol. Rev. 229, 114-125
-
(2009)
Immunol. Rev.
, vol.229
, pp. 114-125
-
-
Riley, J.L.1
-
21
-
-
79953209723
-
Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering
-
Yu, C., Sonnen, A. F., George, R., Dessailly, B. H., Stagg, L. J., Evans, E. J., Orengo, C. A., Stuart, D. I., Ladbury, J. E., Ikemizu, S., Gilbert, R. J., and Davis, S. J. (2011) Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering. J. Biol. Chem. 286, 6685-6696
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 6685-6696
-
-
Yu, C.1
Sonnen, A.F.2
George, R.3
Dessailly, B.H.4
Stagg, L.J.5
Evans, E.J.6
Orengo, C.A.7
Stuart, D.I.8
Ladbury, J.E.9
Ikemizu, S.10
Gilbert, R.J.11
Davis, S.J.12
-
22
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
Butte, M. J., Keir, M. E., Phamduy, T. B., Sharpe, A. H., and Freeman, G. J. (2007) Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 27, 111-122
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
23
-
-
46749114315
-
Interaction of human PD-L1 and B7-1
-
Butte, M. J., Peña-Cruz, V., Kim, M. J., Freeman, G. J., and Sharpe, A. H. (2008) Interaction of human PD-L1 and B7-1. Mol. Immunol. 45, 3567-3572
-
(2008)
Mol. Immunol.
, vol.45
, pp. 3567-3572
-
-
Butte, M.J.1
Peña-Cruz, V.2
Kim, M.J.3
Freeman, G.J.4
Sharpe, A.H.5
-
24
-
-
42949160646
-
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
-
Lin, D. Y., Tanaka, Y., Iwasaki, M., Gittis, A. G., Su, H. P., Mikami, B., Okazaki, T., Honjo, T., Minato, N., and Garboczi, D. N. (2008) The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc. Natl. Acad. Sci. U. S. A. 105, 3011-3016
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 3011-3016
-
-
Lin, D.Y.1
Tanaka, Y.2
Iwasaki, M.3
Gittis, A.G.4
Su, H.P.5
Mikami, B.6
Okazaki, T.7
Honjo, T.8
Minato, N.9
Garboczi, D.N.10
-
25
-
-
48749095324
-
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2
-
Lázár-Molnár, E., Yan, Q., Cao, E., Ramagopal, U., Nathenson, S. G., and Almo, S. C. (2008) Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc. Natl. Acad. Sci. U. S. A. 105, 10483-10488
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 10483-10488
-
-
Lázár-Molnár, E.1
Yan, Q.2
Cao, E.3
Ramagopal, U.4
Nathenson, S.G.5
Almo, S.C.6
-
26
-
-
0026431066
-
Cell adhesion. A birth certificate for CD2
-
Springer, T. A. (1991) Cell adhesion. A birth certificate for CD2. Nature 353, 704-705
-
(1991)
Nature
, vol.353
, pp. 704-705
-
-
Springer, T.A.1
-
27
-
-
0025372845
-
High level expression in Chinese hamster ovary cells of soluble forms of CD4 T lymphocyte glycoprotein including glycosylation variants
-
Davis, S. J., Ward, H. A., Puklavec, M. J., Willis, A. C., Williams, A. F., and Barclay, A. N. (1990) High level expression in Chinese hamster ovary cells of soluble forms of CD4 T lymphocyte glycoprotein including glycosylation variants. J. Biol. Chem. 265, 10410-10418
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 10410-10418
-
-
Davis, S.J.1
Ward, H.A.2
Puklavec, M.J.3
Willis, A.C.4
Williams, A.F.5
Barclay, A.N.6
-
28
-
-
0036669785
-
The interaction properties of costimulatory molecules revisited
-
Collins, A. V., Brodie, D. W., Gilbert, R. J., Iaboni, A., Manso-Sancho, R., Walse, B., Stuart, D. I., van der Merwe, P. A., and Davis, S. J. (2002) The interaction properties of costimulatory molecules revisited. Immunity 17, 201-210
-
(2002)
Immunity
, vol.17
, pp. 201-210
-
-
Collins, A.V.1
Brodie, D.W.2
Gilbert, R.J.3
Iaboni, A.4
Manso-Sancho, R.5
Walse, B.6
Stuart, D.I.7
Van Der Merwe, P.A.8
Davis, S.J.9
-
29
-
-
0031054242
-
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
-
van der Merwe, P. A., Bodian, D. L., Daenke, S., Linsley, P., and Davis, S. J. (1997) CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J. Exp. Med. 185, 393-403
-
(1997)
J. Exp. Med.
, vol.185
, pp. 393-403
-
-
Van Der Merwe, P.A.1
Bodian, D.L.2
Daenke, S.3
Linsley, P.4
Davis, S.J.5
-
30
-
-
33748670126
-
NMR assignment of the mTOR domain responsible for rapamycin binding
-
Veverka, V., Lennie, G., Crabbe, T., Bird, I., Taylor, R. J., and Carr, M. D. (2006) NMR assignment of the mTOR domain responsible for rapamycin binding. J. Biomol. NMR 36, 3
-
(2006)
J. Biomol. NMR
, vol.36
, pp. 3
-
-
Veverka, V.1
Lennie, G.2
Crabbe, T.3
Bird, I.4
Taylor, R.J.5
Carr, M.D.6
-
31
-
-
34250314906
-
NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4
-
Waters, L. C., Böhm, M., Veverka, V., Muskett, F. W., Frenkiel, T. A., Kelly, G. P., Prescott, A., Dosanjh, N. S., Klempnauer, K. H., and Carr, M. D. (2006) NMR assignment and secondary structure determination of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4. J. Biomol. NMR 36, 18
-
(2006)
J. Biomol. NMR
, vol.36
, pp. 18
-
-
Waters, L.C.1
Böhm, M.2
Veverka, V.3
Muskett, F.W.4
Frenkiel, T.A.5
Kelly, G.P.6
Prescott, A.7
Dosanjh, N.S.8
Klempnauer, K.H.9
Carr, M.D.10
-
32
-
-
9244228578
-
Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6
-
Renshaw, P. S., Veverka, V., Kelly, G., Frenkiel, T. A., Williamson, R. A., Gordon, S. V., Hewinson, R. G., and Carr, M. D. (2004) Sequence-specific assignment and secondary structure determination of the 195-residue complex formed by the Mycobacterium tuberculosis proteins CFP-10 and ESAT-6. J. Biomol. NMR 30, 225-226
-
(2004)
J. Biomol. NMR
, vol.30
, pp. 225-226
-
-
Renshaw, P.S.1
Veverka, V.2
Kelly, G.3
Frenkiel, T.A.4
Williamson, R.A.5
Gordon, S.V.6
Hewinson, R.G.7
Carr, M.D.8
-
33
-
-
70450274968
-
High resolution NMR-based model for the structure of a scFv-IL-1β complex. Potential for NMR as a key tool in therapeutic antibody design and development
-
Wilkinson, I. C., Hall, C. J., Veverka, V., Shi, J. Y., Muskett, F. W., Stephens, P. E., Taylor, R. J., Henry, A. J., and Carr, M. D. (2009) High resolution NMR-based model for the structure of a scFv-IL-1β complex. Potential for NMR as a key tool in therapeutic antibody design and development. J. Biol. Chem. 284, 31928-31935
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 31928-31935
-
-
Wilkinson, I.C.1
Hall, C.J.2
Veverka, V.3
Shi, J.Y.4
Muskett, F.W.5
Stephens, P.E.6
Taylor, R.J.7
Henry, A.J.8
Carr, M.D.9
-
34
-
-
0036308102
-
Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA
-
Herrmann, T., Güntert, P., and Wüthrich, K. (2002) Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J. Mol. Biol. 319, 209-227
-
(2002)
J. Mol. Biol.
, vol.319
, pp. 209-227
-
-
Herrmann, T.1
Güntert, P.2
Wüthrich, K.3
-
35
-
-
38549134335
-
Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor. Compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR
-
Veverka, V., Crabbe, T., Bird, I., Lennie, G., Muskett, F. W., Taylor, R. J., and Carr, M. D. (2008) Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor. Compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR. Oncogene 27, 585-595
-
(2008)
Oncogene
, vol.27
, pp. 585-595
-
-
Veverka, V.1
Crabbe, T.2
Bird, I.3
Lennie, G.4
Muskett, F.W.5
Taylor, R.J.6
Carr, M.D.7
-
36
-
-
68349093958
-
+. A hybrid method for predicting protein backbone torsion angles from NMR chemical shifts
-
+. A hybrid method for predicting protein backbone torsion angles from NMR chemical shifts. J. Biomol. NMR 44, 213-223
-
(2009)
J. Biomol. NMR
, vol.44
, pp. 213-223
-
-
Shen, Y.1
Delaglio, F.2
Cornilescu, G.3
Bax, A.4
-
37
-
-
0026259488
-
Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints
-
Güntert, P., and Wüthrich, K. (1991) Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints. J. Biomol. NMR 1, 447-456
-
(1991)
J. Biomol. NMR
, vol.1
, pp. 447-456
-
-
Güntert, P.1
Wüthrich, K.2
-
38
-
-
23444454552
-
The Amber biomolecular simulation programs
-
Case, D. A., Cheatham, T. E., 3rd, Darden, T., Gohlke, H., Luo, R., Merz, K. M., Jr., Onufriev, A., Simmerling, C., Wang, B., and Woods, R. J. (2005) The Amber biomolecular simulation programs. J. Comput. Chem. 26, 1668-1688
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 1668-1688
-
-
Case, D.A.1
Cheatham III, T.E.2
Darden, T.3
Gohlke, H.4
Luo, R.5
Merz Jr., K.M.6
Onufriev, A.7
Simmerling, C.8
Wang, B.9
Woods, R.J.10
-
39
-
-
0034701222
-
Molecular dynamics simulations of nucleic acids using a generalized Born solvation model
-
Tsui, V., and Case, D. A. (2000) Molecular dynamics simulations of nucleic acids using a generalized Born solvation model. J. Am. Chem. Soc. 122, 2489-2498
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 2489-2498
-
-
Tsui, V.1
Case, D.A.2
-
40
-
-
0029881007
-
MOLMOL. A program for display and analysis of macromolecular structures
-
Koradi, R., Billeter, M., and Wüthrich, K. (1996) MOLMOL. A program for display and analysis of macromolecular structures. J. Mol. Graph. 14, 51-55, 29-32
-
(1996)
J. Mol. Graph.
, vol.14
, Issue.51-55
, pp. 29-32
-
-
Koradi, R.1
Billeter, M.2
Wüthrich, K.3
-
41
-
-
34547592557
-
MolProbity. All-atom contacts and structure validation for proteins and nucleic acids
-
Davis, I. W., Leaver-Fay, A., Chen, V. B., Block, J. N., Kapral, G. J., Wang, X., Murray, L. W., Arendall, W. B., 3rd, Snoeyink, J., Richardson, J. S., and Richardson, D. C. (2007) MolProbity. All-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Res. 35, W375-W383
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
Davis, I.W.1
Leaver-Fay, A.2
Chen, V.B.3
Block, J.N.4
Kapral, G.J.5
Wang, X.6
Murray, L.W.7
Arendall III, W.B.8
Snoeyink, J.9
Richardson, J.S.10
Richardson, D.C.11
-
43
-
-
0030457156
-
+ binding site on the MurB enzyme by NMR
-
+ binding site on the MurB enzyme by NMR. Nat. Struct. Mol. Biol. 3, 995-997
-
(1996)
Nat. Struct. Mol. Biol.
, vol.3
, pp. 995-997
-
-
Farmer, B.T.1
Constantine, K.L.2
Goldfarb, V.3
Friedrichs, M.S.4
Wittekind, M.5
Yanchunas, J.6
Robertson, J.G.7
Mueller, L.8
-
44
-
-
0032555593
-
High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3
-
Muskett, F. W., Frenkiel, T. A., Feeney, J., Freedman, R. B., Carr, M. D., and Williamson, R. A. (1998) High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3. J. Biol. Chem. 273, 21736-21743
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21736-21743
-
-
Muskett, F.W.1
Frenkiel, T.A.2
Feeney, J.3
Freedman, R.B.4
Carr, M.D.5
Williamson, R.A.6
-
45
-
-
0030666085
-
Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation
-
Williamson, R. A., Carr, M. D., Frenkiel, T. A., Feeney, J., and Freedman, R. B. (1997) Mapping the binding site for matrix metalloproteinase on the N-terminal domain of the tissue inhibitor of metalloproteinases-2 by NMR chemical shift perturbation. Biochemistry 36, 13882-13889
-
(1997)
Biochemistry
, vol.36
, pp. 13882-13889
-
-
Williamson, R.A.1
Carr, M.D.2
Frenkiel, T.A.3
Feeney, J.4
Freedman, R.B.5
-
46
-
-
33749378972
-
Crystal structure and binding properties of the CD2 and CD244 (2B4) - Binding protein, CD48
-
Evans, E. J., Castro, M. A., O'Brien, R., Kearney, A., Walsh, H., Sparks, L. M., Tucknott, M. G., Davies, E. A., Carmo, A. M., van der Merwe, P. A., Stuart, D. I., Jones, E. Y., Ladbury, J. E., Ikemizu, S., and Davis, S. J. (2006) Crystal structure and binding properties of the CD2 and CD244 (2B4) - binding protein, CD48. J. Biol. Chem. 281, 29309-29320
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29309-29320
-
-
Evans, E.J.1
Castro, M.A.2
O'Brien, R.3
Kearney, A.4
Walsh, H.5
Sparks, L.M.6
Tucknott, M.G.7
Davies, E.A.8
Carmo, A.M.9
Van Der Merwe, P.A.10
Stuart, D.I.11
Jones, E.Y.12
Ladbury, J.E.13
Ikemizu, S.14
Davis, S.J.15
-
47
-
-
20144376352
-
Crystal structure of a soluble CD28-Fab complex
-
Evans, E. J., Esnouf, R. M., Manso-Sancho, R., Gilbert, R. J., James, J. R., Yu, C., Fennelly, J. A., Vowles, C., Hanke, T., Walse, B., Hünig, T., Sørensen, P., Stuart, D. I., and Davis, S. J. (2005) Crystal structure of a soluble CD28-Fab complex. Nat. Immunol. 6, 271-279
-
(2005)
Nat. Immunol.
, vol.6
, pp. 271-279
-
-
Evans, E.J.1
Esnouf, R.M.2
Manso-Sancho, R.3
Gilbert, R.J.4
James, J.R.5
Yu, C.6
Fennelly, J.A.7
Vowles, C.8
Hanke, T.9
Walse, B.10
Hünig, T.11
Sørensen, P.12
Stuart, D.I.13
Davis, S.J.14
-
48
-
-
0024356301
-
Rapid measurement of binding constants and heats of binding using a new titration calorimeter
-
Wiseman, T., Williston, S., Brandts, J. F., and Lin, L. N. (1989) Rapid measurement of binding constants and heats of binding using a new titration calorimeter. Anal. Biochem. 179, 131-137
-
(1989)
Anal. Biochem.
, vol.179
, pp. 131-137
-
-
Wiseman, T.1
Williston, S.2
Brandts, J.F.3
Lin, L.N.4
-
49
-
-
0030266484
-
Sensing the heat. The application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions
-
Ladbury, J. E., and Chowdhry, B. Z. (1996) Sensing the heat. The application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions. Chem. Biol. 3, 791-801
-
(1996)
Chem. Biol.
, vol.3
, pp. 791-801
-
-
Ladbury, J.E.1
Chowdhry, B.Z.2
-
50
-
-
22544465538
-
A theoretical framework for quantitative analysis of the molecular basis of costimulation
-
Jansson, A., Barnes, E., Klenerman, P., Harlén, M., Sørensen, P., Davis, S. J., and Nilsson, P. (2005) A theoretical framework for quantitative analysis of the molecular basis of costimulation. J. Immunol. 175, 1575-1585
-
(2005)
J. Immunol.
, vol.175
, pp. 1575-1585
-
-
Jansson, A.1
Barnes, E.2
Klenerman, P.3
Harlén, M.4
Sørensen, P.5
Davis, S.J.6
Nilsson, P.7
-
51
-
-
81955161893
-
Quantitative analysis predicts the relative therapeutic efficacy of different forms of CTLA4Ig
-
Jansson, A., and Davis, S. J. (2011) Quantitative analysis predicts the relative therapeutic efficacy of different forms of CTLA4Ig. Mol. Immunol. 49, 527-536
-
(2011)
Mol. Immunol.
, vol.49
, pp. 527-536
-
-
Jansson, A.1
Davis, S.J.2
-
52
-
-
0033824470
-
DaliLite workbench for protein structure comparison
-
Holm, L., and Park, J. (2000) DaliLite workbench for protein structure comparison. Bioinformatics 16, 566-567
-
(2000)
Bioinformatics
, vol.16
, pp. 566-567
-
-
Holm, L.1
Park, J.2
-
53
-
-
12144290320
-
Structural and functional analysis of the costimulatory receptor programmed death-1
-
Zhang, X., Schwartz, J. C., Guo, X., Bhatia, S., Cao, E., Lorenz, M., Cammer, M., Chen, L., Zhang, Z. Y., Edidin, M. A., Nathenson, S. G., and Almo, S. C. (2004) Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity 20, 337-347
-
(2004)
Immunity
, vol.20
, pp. 337-347
-
-
Zhang, X.1
Schwartz, J.C.2
Guo, X.3
Bhatia, S.4
Cao, E.5
Lorenz, M.6
Cammer, M.7
Chen, L.8
Zhang, Z.Y.9
Edidin, M.A.10
Nathenson, S.G.11
Almo, S.C.12
-
54
-
-
29744462591
-
PD-L2: PD-1 involvement in T cell proliferation, cytokine production, and integrin-mediated adhesion
-
Saunders, P. A., Hendrycks, V. R., Lidinsky, W. A., and Woods, M. L. (2005) PD-L2: PD-1 involvement in T cell proliferation, cytokine production, and integrin-mediated adhesion. Eur. J. Immunol. 35, 3561-3569
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 3561-3569
-
-
Saunders, P.A.1
Hendrycks, V.R.2
Lidinsky, W.A.3
Woods, M.L.4
-
55
-
-
0037312070
-
Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis
-
Dong, H., Strome, S. E., Matteson, E. L., Moder, K. G., Flies, D. B., Zhu, G., Tamura, H., Driscoll, C. L., and Chen, L. (2003) Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis. J. Clin. Invest. 111, 363-370
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 363-370
-
-
Dong, H.1
Strome, S.E.2
Matteson, E.L.3
Moder, K.G.4
Flies, D.B.5
Zhu, G.6
Tamura, H.7
Driscoll, C.L.8
Chen, L.9
-
56
-
-
0018101150
-
Models for the specific adhesion of cells to cells
-
Bell, G. I. (1978) Models for the specific adhesion of cells to cells. Science 200, 618-627
-
(1978)
Science
, vol.200
, pp. 618-627
-
-
Bell, G.I.1
-
57
-
-
0028963227
-
Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation
-
Prabhu Das, M. R., Zamvil, S. S., Borriello, F., Weiner, H. L., Sharpe, A. H., and Kuchroo, V. K. (1995) Reciprocal expression of co-stimulatory molecules, B7-1 and B7-2, on murine T cells following activation. Eur. J. Immunol. 25, 207-211
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 207-211
-
-
Prabhu Das, M.R.1
Zamvil, S.S.2
Borriello, F.3
Weiner, H.L.4
Sharpe, A.H.5
Kuchroo, V.K.6
-
58
-
-
0027473759
-
B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro
-
Sansom, D. M., and Hall, N. D. (1993) B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro. Eur. J. Immunol. 23, 295-298
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 295-298
-
-
Sansom, D.M.1
Hall, N.D.2
-
59
-
-
0027511603
-
Functional expression of B7/BB1 on activated T lymphocytes
-
Azuma, M., Yssel, H., Phillips, J. H., Spits, H., and Lanier, L. L. (1993) Functional expression of B7/BB1 on activated T lymphocytes. J. Exp. Med. 177, 845-850
-
(1993)
J. Exp. Med.
, vol.177
, pp. 845-850
-
-
Azuma, M.1
Yssel, H.2
Phillips, J.H.3
Spits, H.4
Lanier, L.L.5
-
60
-
-
0035967146
-
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
-
Stamper, C. C., Zhang, Y., Tobin, J. F., Erbe, D. V., Ikemizu, S., Davis, S. J., Stahl, M. L., Seehra, J., Somers, W. S., and Mosyak, L. (2001) Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature 410, 608-611
-
(2001)
Nature
, vol.410
, pp. 608-611
-
-
Stamper, C.C.1
Zhang, Y.2
Tobin, J.F.3
Erbe, D.V.4
Ikemizu, S.5
Davis, S.J.6
Stahl, M.L.7
Seehra, J.8
Somers, W.S.9
Mosyak, L.10
-
61
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
Parry, R. V., Chemnitz, J. M., Frauwirth, K. A., Lanfranco, A. R., Braunstein, I., Kobayashi, S. V., Linsley, P. S., Thompson, C. B., and Riley, J. L. (2005) CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol. Cell Biol. 25, 9543-9553
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
Lanfranco, A.R.4
Braunstein, I.5
Kobayashi, S.V.6
Linsley, P.S.7
Thompson, C.B.8
Riley, J.L.9
-
62
-
-
33749038866
-
Reversal of the TCR stop signal by CTLA-4
-
Schneider, H., Downey, J., Smith, A., Zinselmeyer, B. H., Rush, C., Brewer, J. M., Wei, B., Hogg, N., Garside, P., and Rudd, C. E. (2006) Reversal of the TCR stop signal by CTLA-4. Science 313, 1972-1975
-
(2006)
Science
, vol.313
, pp. 1972-1975
-
-
Schneider, H.1
Downey, J.2
Smith, A.3
Zinselmeyer, B.H.4
Rush, C.5
Brewer, J.M.6
Wei, B.7
Hogg, N.8
Garside, P.9
Rudd, C.E.10
-
63
-
-
79955529454
-
Transendocytosis of CD80 and CD86. A molecular basis for the cell-extrinsic function of CTLA-4
-
Qureshi, O. S., Zheng, Y., Nakamura, K., Attridge, K., Manzotti, C., Schmidt, E. M., Baker, J., Jeffery, L. E., Kaur, S., Briggs, Z., Hou, T. Z., Futter, C. E., Anderson, G., Walker, L. S., and Sansom, D. M. (2011) Transendocytosis of CD80 and CD86. A molecular basis for the cell-extrinsic function of CTLA-4. Science 332, 600-603
-
(2011)
Science
, vol.332
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
Attridge, K.4
Manzotti, C.5
Schmidt, E.M.6
Baker, J.7
Jeffery, L.E.8
Kaur, S.9
Briggs, Z.10
Hou, T.Z.11
Futter, C.E.12
Anderson, G.13
Walker, L.S.14
Sansom, D.M.15
-
65
-
-
21144437398
-
In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses
-
Shin, T., Yoshimura, K., Shin, T., Crafton, E. B., Tsuchiya, H., Housseau, F., Koseki, H., Schulick, R. D., Chen, L., and Pardoll, D. M. (2005) In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J. Exp. Med. 201, 1531-1541
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1531-1541
-
-
Shin, T.1
Yoshimura, K.2
Shin, T.3
Crafton, E.B.4
Tsuchiya, H.5
Housseau, F.6
Koseki, H.7
Schulick, R.D.8
Chen, L.9
Pardoll, D.M.10
|