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Volumn 1831, Issue 6, 2013, Pages 1158-1166

Identification of triacylglycerol and steryl ester synthases of the methylotrophic yeast Pichia pastoris

Author keywords

Acyltransferase; Lipid droplet; Pichia pastoris; Steryl ester; Triacylglycerol

Indexed keywords

DIACYLGLYCEROL ACYLTRANSFERASE; FAT DROPLET; POLYUNSATURATED FATTY ACID; STERYL ESTER SYNTHASE; SYNTHETASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84876900509     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.03.004     Document Type: Article
Times cited : (14)

References (39)
  • 2
    • 14744285206 scopus 로고    scopus 로고
    • Expression of heterologous proteins in Pichia pastoris: A useful experimental tool in protein engineering and production
    • R. Daly, and M.T. Hearn Expression of heterologous proteins in Pichia pastoris: a useful experimental tool in protein engineering and production J. Mol. Recognit. 18 2005 119 138
    • (2005) J. Mol. Recognit. , vol.18 , pp. 119-138
    • Daly, R.1    Hearn, M.T.2
  • 3
    • 17244363998 scopus 로고    scopus 로고
    • Heterologous protein production using the Pichia pastoris expression system
    • S. Macauley-Patrick, M.L. Fazenda, B. McNeil, and L.M. Harvey Heterologous protein production using the Pichia pastoris expression system Yeast 22 2005 249 270
    • (2005) Yeast , vol.22 , pp. 249-270
    • Macauley-Patrick, S.1    Fazenda, M.L.2    McNeil, B.3    Harvey, L.M.4
  • 8
    • 0034717265 scopus 로고    scopus 로고
    • A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast
    • P. Oelkers, A. Tinkelenberg, N. Erdeniz, D. Cromley, J.T. Billheimer, and S.L. Sturley A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast J. Biol. Chem. 275 2000 15609 15612
    • (2000) J. Biol. Chem. , vol.275 , pp. 15609-15612
    • Oelkers, P.1    Tinkelenberg, A.2    Erdeniz, N.3    Cromley, D.4    Billheimer, J.T.5    Sturley, S.L.6
  • 9
    • 0034612345 scopus 로고    scopus 로고
    • Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
    • A. Dahlqvist, U. Stahl, M. Lenman, A. Banas, M. Lee, L. Sandager, H. Ronne, and S. Stymne Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants Proc. Natl. Acad. Sci. U. S. A. 97 2000 6487 6492
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 6487-6492
    • Dahlqvist, A.1    Stahl, U.2    Lenman, M.3    Banas, A.4    Lee, M.5    Sandager, L.6    Ronne, H.7    Stymne, S.8
  • 11
    • 0036135597 scopus 로고    scopus 로고
    • Synthesis of triacylglycerols by the acyl-coenzyme A:diacylglycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae
    • D. Sorger, and G. Daum Synthesis of triacylglycerols by the acyl-coenzyme A:diacylglycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae J. Bacteriol. 184 2002 519 524
    • (2002) J. Bacteriol. , vol.184 , pp. 519-524
    • Sorger, D.1    Daum, G.2
  • 12
    • 0029835340 scopus 로고    scopus 로고
    • Molecular cloning and characterization of two isoforms of Saccharomyces cerevisiae acyl-CoA:sterol acyltransferase
    • C. Yu, N.J. Kennedy, C.Y. Chang, and J.A. Rothblatt Molecular cloning and characterization of two isoforms of Saccharomyces cerevisiae acyl-CoA:sterol acyltransferase J. Biol. Chem. 271 1996 24157 24163
    • (1996) J. Biol. Chem. , vol.271 , pp. 24157-24163
    • Yu, C.1    Kennedy, N.J.2    Chang, C.Y.3    Rothblatt, J.A.4
  • 13
    • 0033974053 scopus 로고    scopus 로고
    • Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae
    • D. Zweytick, E. Leitner, S.D. Kohlwein, C. Yu, J. Rothblatt, and G. Daum Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae Eur. J. Biochem. 267 2000 1075 1082
    • (2000) Eur. J. Biochem. , vol.267 , pp. 1075-1082
    • Zweytick, D.1    Leitner, E.2    Kohlwein, S.D.3    Yu, C.4    Rothblatt, J.5    Daum, G.6
  • 14
    • 79961114473 scopus 로고    scopus 로고
    • YALI0E32769g (DGA1) and YALI0E16797g (LRO1) encode major triacylglycerol synthases of the oleaginous yeast Yarrowia lipolytica
    • K. Athenstaedt YALI0E32769g (DGA1) and YALI0E16797g (LRO1) encode major triacylglycerol synthases of the oleaginous yeast Yarrowia lipolytica Biochim. Biophys. Acta 1811 2011 587 596
    • (2011) Biochim. Biophys. Acta , vol.1811 , pp. 587-596
    • Athenstaedt, K.1
  • 15
    • 84857917010 scopus 로고    scopus 로고
    • Identification and characterization of DGA2, an acyltransferase of the DGAT1 acyl-CoA:diacylglycerol acyltransferase family in the oleaginous yeast Yarrowia lipolytica. New insights into the storage lipid metabolism of oleaginous yeasts
    • A. Beopoulos, R. Haddouche, P. Kabran, T. Dulermo, T. Chardot, and J.M. Nicaud Identification and characterization of DGA2, an acyltransferase of the DGAT1 acyl-CoA:diacylglycerol acyltransferase family in the oleaginous yeast Yarrowia lipolytica. New insights into the storage lipid metabolism of oleaginous yeasts Appl. Microbiol. Biotechnol. 93 2012 1523 1537
    • (2012) Appl. Microbiol. Biotechnol. , vol.93 , pp. 1523-1537
    • Beopoulos, A.1    Haddouche, R.2    Kabran, P.3    Dulermo, T.4    Chardot, T.5    Nicaud, J.M.6
  • 16
    • 47749150637 scopus 로고    scopus 로고
    • Structural and biochemical properties of lipid particles from the yeast Saccharomyces cerevisiae
    • T. Czabany, A. Wagner, D. Zweytick, K. Lohner, E. Leitner, E. Ingolic, and G. Daum Structural and biochemical properties of lipid particles from the yeast Saccharomyces cerevisiae J. Biol. Chem. 283 2008 17065 17074
    • (2008) J. Biol. Chem. , vol.283 , pp. 17065-17074
    • Czabany, T.1    Wagner, A.2    Zweytick, D.3    Lohner, K.4    Leitner, E.5    Ingolic, E.6    Daum, G.7
  • 19
    • 0027231368 scopus 로고
    • Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism
    • E. Zinser, F. Paltauf, and G. Daum Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism J. Bacteriol. 175 1993 2853 2858
    • (1993) J. Bacteriol. , vol.175 , pp. 2853-2858
    • Zinser, E.1    Paltauf, F.2    Daum, G.3
  • 20
    • 0034879653 scopus 로고    scopus 로고
    • Transcriptional regulation of the two sterol esterification genes in the yeast Saccharomyces cerevisiae
    • K. Jensen-Pergakes, Z. Guo, M. Giattina, S.L. Sturley, and M. Bard Transcriptional regulation of the two sterol esterification genes in the yeast Saccharomyces cerevisiae J. Bacteriol. 183 2001 4950 4957
    • (2001) J. Bacteriol. , vol.183 , pp. 4950-4957
    • Jensen-Pergakes, K.1    Guo, Z.2    Giattina, M.3    Sturley, S.L.4    Bard, M.5
  • 21
    • 0037005998 scopus 로고    scopus 로고
    • Heme-regulated expression of two yeast acyl-CoA:sterol acyltransferases is involved in the specific response of sterol esterification to anaerobiosis
    • M. Valachovic, V. Klobucnikova, P. Griac, and I. Hapala Heme-regulated expression of two yeast acyl-CoA:sterol acyltransferases is involved in the specific response of sterol esterification to anaerobiosis FEMS Microbiol. Lett. 206 2002 121 125
    • (2002) FEMS Microbiol. Lett. , vol.206 , pp. 121-125
    • Valachovic, M.1    Klobucnikova, V.2    Griac, P.3    Hapala, I.4
  • 26
    • 84863090270 scopus 로고    scopus 로고
    • Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology
    • L. Näätsaari, B. Mistlberger, C. Ruth, T. Hajek, F.S. Hartner, and A. Glieder Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology PLoS One 7 2012 e39720
    • (2012) PLoS One , vol.7 , pp. 39720
    • Näätsaari, L.1    Mistlberger, B.2    Ruth, C.3    Hajek, T.4    Hartner, F.S.5    Glieder, A.6
  • 29
    • 0029871347 scopus 로고    scopus 로고
    • PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae
    • A. Wach PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae Yeast 12 1996 259 265
    • (1996) Yeast , vol.12 , pp. 259-265
    • Wach, A.1
  • 32
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues J. Biol. Chem. 226 1957 497 509
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 34
    • 79953858620 scopus 로고    scopus 로고
    • Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis
    • Q. Liu, R.M. Siloto, C.L. Snyder, and R.J. Weselake Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis J. Biol. Chem. 286 2011 13115 13126
    • (2011) J. Biol. Chem. , vol.286 , pp. 13115-13126
    • Liu, Q.1    Siloto, R.M.2    Snyder, C.L.3    Weselake, R.J.4
  • 35
    • 38349033129 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae phospholipid:diacylglycerol acyl transferase (PDAT) devoid of its membrane anchor region is a soluble and active enzyme retaining its substrate specificities
    • A. Ghosal, A. Banas, U. Ståhl, A. Dahlqvist, Y. Lindqvist, and S. Stymne Saccharomyces cerevisiae phospholipid:diacylglycerol acyl transferase (PDAT) devoid of its membrane anchor region is a soluble and active enzyme retaining its substrate specificities Biochim. Biophys. Acta 1771 2007 1457 1463
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 1457-1463
    • Ghosal, A.1    Banas, A.2    Ståhl, U.3    Dahlqvist, A.4    Lindqvist, Y.5    Stymne, S.6
  • 36
    • 0034879955 scopus 로고    scopus 로고
    • Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences
    • Z. Guo, D. Cromley, J.T. Billheimer, and S.L. Sturley Identification of potential substrate-binding sites in yeast and human acyl-CoA sterol acyltransferases by mutagenesis of conserved sequences J. Lipid Res. 42 2001 1282 1291
    • (2001) J. Lipid Res. , vol.42 , pp. 1282-1291
    • Guo, Z.1    Cromley, D.2    Billheimer, J.T.3    Sturley, S.L.4
  • 37
    • 38049120873 scopus 로고    scopus 로고
    • Lipid-induced cell dysfunction and cell death: Lessons from yeast
    • S.D. Kohlwein, and J. Petschnigg Lipid-induced cell dysfunction and cell death: lessons from yeast Curr. Hypertens. Rep. 9 2007 455 461
    • (2007) Curr. Hypertens. Rep. , vol.9 , pp. 455-461
    • Kohlwein, S.D.1    Petschnigg, J.2
  • 38
    • 71449102613 scopus 로고    scopus 로고
    • Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast
    • J. Petschnigg, H. Wolinski, D. Kolb, G. Zellnig, C.F. Kurat, K. Natter, and S.D. Kohlwein Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast J. Biol. Chem. 284 2009 30981 30993
    • (2009) J. Biol. Chem. , vol.284 , pp. 30981-30993
    • Petschnigg, J.1    Wolinski, H.2    Kolb, D.3    Zellnig, G.4    Kurat, C.F.5    Natter, K.6    Kohlwein, S.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.