Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells

Lipids in Health and Disease

Volumn 9, Issue , 2010, Pages

  Pusks, Lszlá G ^a,b,c   Fehér, Lilina Z ^a   Vizler, Csaba ^c   Ayaydin, Ferhan ^c   Rsá, Erzsébet ^d   Molnr, Eszter ^b,c   Magyary, Istvn ^e   Kanizsai, Ivn ^a   Gyuris, Mriá ^a   Madcsi, Ramána ^a   Fbin, Gabriella ^b   Farkas, Klaudia ^f   Hegyi, Péter ^f   Baska, Ferenc ^g   Zsvri, Béla ^a   Kitajka, Klra ^a,c  

^a AVIDIN LTD   (Hungary)

^b Avicor Ltd   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d NATIONAL INSTITUTE OF ONCOLOGY   (Hungary)

^e Biotecont Ltd   (Hungary)

^f UNIVERSITY OF SZEGED   (Hungary)

^g SZENT ISTVÁN UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DIISOPROPYLPHENYL 4 CYCLOPENTYL 5,6,7 TRIFLUOROPHTHALIMIDE; 2,6 DIISOPROPYLPHENYL 4 MORPHOLINE 5,6,7 TRIFLUOROPHTHALIMIDE; 2,6 DIISOPROPYLPHENYL 5 ETHYL 5,6,7 TRIFLUOROPHTHALIMIDE; AC 1041; AC 177; AC 202; ACTIVATING TRANSCRIPTION FACTOR 3; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CALCIUM; CALCIUM CHELATING AGENT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN 3; DOCOSAHEXAENOIC ACID; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HERPUD1 PROTEIN; ICOSAPENTAENOIC ACID; INHIBITOR OF GROWTH 3 PROTEIN; LARGE TUMOR SUPPRESSOR 2 PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OLEIC ACID; PHTHALIMIDE DERIVATIVE; POLYUNSATURATED FATTY ACID; PROTEIN P53; REACTIVE OXYGEN METABOLITE; THALIDOMIDE DERIVATIVE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; DRUG DERIVATIVE; THALIDOMIDE; UNSATURATED FATTY ACID;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CANCER CELL CULTURE; CELL DEATH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG SYNTHESIS; EMBRYO; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GLIOBLASTOMA; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA; LIVER CELL CARCINOMA; MALE; MELANOMA; METASTASIS; MUSCLE DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN DEGRADATION; RAT; SINGLE DRUG DOSE; TUMOR SUPPRESSOR GENE; UPREGULATION; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; DRUG POTENTIATION; METABOLISM; NEOPLASM; PATHOLOGY; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALIA; DANIO RERIO; EUKARYOTA;

ANIMALS; CELL LINE, TUMOR; DRUG SYNERGISM; EMBRYO, NONMAMMALIAN; ENDOPLASMIC RETICULUM; FATTY ACIDS, UNSATURATED; HOMEOSTASIS; HUMANS; NEOPLASMS; OXIDATIVE STRESS; THALIDOMIDE; ZEBRAFISH;

EID: 77952816497     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-9-56     Document Type: Article

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