Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 17, 2013, Pages

  Yoshida, Soichiro ^a   Tsutsumi, Shinji ^a   Muhlebach, Guillaume ^b   Sourbier, Carole ^a   Lee, Min Jung ^a   Lee, Sunmin ^a   Vartholomaiou, Evangelia ^b   Tatokoro, Manabu ^a,c   Beebe, Kristin ^a   Miyajima, Naoto ^a   Mohney, Robert P ^d   Chen, Yang ^d   Hasumi, Hisashi ^a   Xu, Wanping ^a   Fukushima, Hiroshi ^c   Nakamura, Ken ^e   Koga, Fumitaka ^c   Kihara, Kazunori ^c   Trepel, Jane ^a   Picard, Didier ^b   Neckers, Leonard ^a   more..

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d METABOLON INC   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHAPERONE; HEAT SHOCK PROTEIN 90; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 1; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; FATTY ACID OXIDATION; FIBROBLAST; GLUCOSE METABOLISM; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TUMOR CELL;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; GLYCOLYSIS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR CHAPERONES; NEOPLASM INVASIVENESS; NIH 3T3 CELLS; OXIDATIVE PHOSPHORYLATION; RNA INTERFERENCE; SRC-FAMILY KINASES; TRANSFECTION;

EID: 84876862267     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1220659110     Document Type: Article

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