-
1
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG, (2000) Obesity as a medical problem. Nature 404: 635-643.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
2
-
-
0034119138
-
The perils of portliness: causes and consequences of visceral adiposity
-
Montague CT, O'Rahilly S, (2000) The perils of portliness: causes and consequences of visceral adiposity. Diabetes 49: 883-888.
-
(2000)
Diabetes
, vol.49
, pp. 883-888
-
-
Montague, C.T.1
O'Rahilly, S.2
-
3
-
-
79952031235
-
Pathophysiologic mechanisms linking adipose tissue and cardiometabolic risk
-
Allende-Vigo MZ, (2010) Pathophysiologic mechanisms linking adipose tissue and cardiometabolic risk. Endocr Pract 16: 692-698.
-
(2010)
Endocr Pract
, vol.16
, pp. 692-698
-
-
Allende-Vigo, M.Z.1
-
5
-
-
0345257085
-
The mitochondriotropic effects of L-carnitine and its esters in the central nervous system
-
Binienda Z, Virmani A, (2003) The mitochondriotropic effects of L-carnitine and its esters in the central nervous system. Curr Med Chem 3: 275-282.
-
(2003)
Curr Med Chem
, vol.3
, pp. 275-282
-
-
Binienda, Z.1
Virmani, A.2
-
6
-
-
0025855351
-
Propionyl-L-carnitine: biochemical significance and possible role in cardiac metabolism
-
Siliprandi N, Di Lisa F, Menabò R, (1991) Propionyl-L-carnitine: biochemical significance and possible role in cardiac metabolism. Cardiovasc Drugs Ther 5: 11-15.
-
(1991)
Cardiovasc Drugs Ther
, vol.5
, pp. 11-15
-
-
Siliprandi, N.1
Di Lisa, F.2
Menabò, R.3
-
7
-
-
23744493081
-
L-Carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products
-
Bueno R, Alvarez de Sotomayor M, Perez-Guerrero C, Gomez-Amores L, Vazquez CM, et al. (2005) L-Carnitine and propionyl-L-carnitine improve endothelial dysfunction in spontaneously hypertensive rats: different participation of NO and COX-products. Life Sci 77: 2082-2097.
-
(2005)
Life Sci
, vol.77
, pp. 2082-2097
-
-
Bueno, R.1
Alvarez de Sotomayor, M.2
Perez-Guerrero, C.3
Gomez-Amores, L.4
Vazquez, C.M.5
-
8
-
-
34547494260
-
l-carnitine and its propionate: improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms
-
de Sotomayor MA, Mingorance C, Rodriguez-Rodriguez R, Marhuenda E, Herrera MD, (2007) l-carnitine and its propionate: improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms. Free Radic Res 4: 884-891.
-
(2007)
Free Radic Res
, vol.4
, pp. 884-891
-
-
de Sotomayor, M.A.1
Mingorance, C.2
Rodriguez-Rodriguez, R.3
Marhuenda, E.4
Herrera, M.D.5
-
9
-
-
34548185680
-
Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR
-
Alvarez de Sotomayor M, Bueno R, Pérez-Guerrero C, Herrera MD, (2007) Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR. J Vasc Res 44: 354-364.
-
(2007)
J Vasc Res
, vol.44
, pp. 354-364
-
-
Alvarez de Sotomayor, M.1
Bueno, R.2
Pérez-Guerrero, C.3
Herrera, M.D.4
-
10
-
-
73349102478
-
Carnitine and type 2 diabetes
-
Mynatt RL, (2009) Carnitine and type 2 diabetes. Diabetes Metab Res Rev 25 (Suppl 1): S45-S49.
-
(2009)
Diabetes Metab Res Rev
, vol.25
, Issue.SUPPL. 1
-
-
Mynatt, R.L.1
-
11
-
-
73749083758
-
Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats
-
Mingorance C, Gonzalez del Pozo M, Dolores Herrera M, Alvarez de Sotomayor M, (2009) Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats. Br J Nutr 102: 1145-1153.
-
(2009)
Br J Nutr
, vol.102
, pp. 1145-1153
-
-
Mingorance, C.1
Gonzalez del Pozo, M.2
Dolores Herrera, M.3
Alvarez de Sotomayor, M.4
-
12
-
-
77953868236
-
Lipid-induced insulin resistance: unravelling the mechanism
-
Samuel VT, Petersen KF, Shulman GI, (2010) Lipid-induced insulin resistance: unravelling the mechanism. Lancet 375: 2267-2277.
-
(2010)
Lancet
, vol.375
, pp. 2267-2277
-
-
Samuel, V.T.1
Petersen, K.F.2
Shulman, G.I.3
-
13
-
-
77955571859
-
Ectopic fat and cardiovascular disease: what is the link?
-
Gastaldelli A, Basta G, (2010) Ectopic fat and cardiovascular disease: what is the link? Nutr Metab Cardiovasc Dis 20: 481-490.
-
(2010)
Nutr Metab Cardiovasc Dis
, vol.20
, pp. 481-490
-
-
Gastaldelli, A.1
Basta, G.2
-
14
-
-
0030033076
-
Effect of propionyl-L-carnitine on the mechanics of right and left papillary muscles from volume-overloaded rat hearts
-
Micheletti R, Giacalone G, Bianchi G, (1996) Effect of propionyl-L-carnitine on the mechanics of right and left papillary muscles from volume-overloaded rat hearts. J Cardiovasc Pharmacol 27: 52-57.
-
(1996)
J Cardiovasc Pharmacol
, vol.27
, pp. 52-57
-
-
Micheletti, R.1
Giacalone, G.2
Bianchi, G.3
-
15
-
-
0021813187
-
Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
-
16
-
-
34548474286
-
Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release
-
Agouni A, Mostefai HA, Porro C, Carusio N, Favre J, et al. (2007) Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release. Faseb J 21: 2735-2741.
-
(2007)
Faseb J
, vol.21
, pp. 2735-2741
-
-
Agouni, A.1
Mostefai, H.A.2
Porro, C.3
Carusio, N.4
Favre, J.5
-
17
-
-
0008321079
-
Enzymatic and polarographic measurements of the respiratory chain complexes
-
Patrick Lestiene (ed). Springer, Berlin
-
Malgat MLT, Durrieu G, Mazat JP, (1999) Enzymatic and polarographic measurements of the respiratory chain complexes. Mitochondrial Diseases Patrick Lestiene (ed). Springer, Berlin.
-
(1999)
Mitochondrial Diseases
-
-
Malgat, M.L.T.1
Durrieu, G.2
Mazat, J.P.3
-
18
-
-
0344413662
-
Carnitine profiles during differentiation and effects of carnitine on differentiation of 3T3-L1 cells
-
Cha YS, Eun JS, Oh SH, (2003) Carnitine profiles during differentiation and effects of carnitine on differentiation of 3T3-L1 cells. J Med Food 6: 163-167.
-
(2003)
J Med Food
, vol.6
, pp. 163-167
-
-
Cha, Y.S.1
Eun, J.S.2
Oh, S.H.3
-
19
-
-
33846203944
-
L-carnitine stimulates lipolysis via induction of the lipolytic gene expression and suppression of the adipogenic gene expression in 3T3-L1 adipocytes
-
Lee MS, Lee HJ, Lee HS, Kim Y, (2006) L-carnitine stimulates lipolysis via induction of the lipolytic gene expression and suppression of the adipogenic gene expression in 3T3-L1 adipocytes. J Med Food 9: 468-473.
-
(2006)
J Med Food
, vol.9
, pp. 468-473
-
-
Lee, M.S.1
Lee, H.J.2
Lee, H.S.3
Kim, Y.4
-
20
-
-
77955223112
-
Lotus leaf extract and L-carnitine influence different processes during the adipocyte life cycle
-
Siegner R, Heuser S, Holtzmann U, Söhle J, Schepky A, et al. (2010) Lotus leaf extract and L-carnitine influence different processes during the adipocyte life cycle. Nutr Metab (Lond) 7: 66-76.
-
(2010)
Nutr Metab (Lond)
, vol.7
, pp. 66-76
-
-
Siegner, R.1
Heuser, S.2
Holtzmann, U.3
Söhle, J.4
Schepky, A.5
-
21
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
Després JP, Lemieux I, (2006) Abdominal obesity and metabolic syndrome. Nature 444: 881-887.
-
(2006)
Nature
, vol.444
, pp. 881-887
-
-
Després, J.P.1
Lemieux, I.2
-
22
-
-
77949895746
-
Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats
-
Amin KA, Nagy MA, (2009) Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats. Diabetol Metab Syndr 1: 17-31.
-
(2009)
Diabetol Metab Syndr
, vol.1
, pp. 17-31
-
-
Amin, K.A.1
Nagy, M.A.2
-
23
-
-
33847646640
-
Carnitine revisited: potential use as adjunctive treatment in diabetes
-
Power RA, Hulver MW, Zhang JY, Dubois J, Marchand RM, et al. (2007) Carnitine revisited: potential use as adjunctive treatment in diabetes. Diabetologia 50: 824-832.
-
(2007)
Diabetologia
, vol.50
, pp. 824-832
-
-
Power, R.A.1
Hulver, M.W.2
Zhang, J.Y.3
Dubois, J.4
Marchand, R.M.5
-
24
-
-
77952526597
-
Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance
-
Kleemann R, van Erk M, Verschuren L, van den Hoek AM, Koek M, et al. (2010) Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance. PLoS One 5: e8817.
-
(2010)
PLoS One
, vol.5
-
-
Kleemann, R.1
van Erk, M.2
Verschuren, L.3
van den Hoek, A.M.4
Koek, M.5
-
26
-
-
42949178968
-
Alterations in hepatic mitochondrial compartment in a model of obesity and insulin resistance
-
Crescenzo R, Bianco F, Falcone I, Prisco M, Liverini G, et al. (2008) Alterations in hepatic mitochondrial compartment in a model of obesity and insulin resistance. Obesity (Silver Spring) 16: 958-64.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 958-964
-
-
Crescenzo, R.1
Bianco, F.2
Falcone, I.3
Prisco, M.4
Liverini, G.5
-
27
-
-
78751582294
-
Effects of a high-fat diet on energy metabolism and ROS production in rat liver
-
Vial G, Dubouchaud H, Couturier K, Cottet-Rousselle C, Taleux N, et al. (2010) Effects of a high-fat diet on energy metabolism and ROS production in rat liver. J Hepatol 54: 348-356.
-
(2010)
J Hepatol
, vol.54
, pp. 348-356
-
-
Vial, G.1
Dubouchaud, H.2
Couturier, K.3
Cottet-Rousselle, C.4
Taleux, N.5
-
28
-
-
20444463198
-
Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect
-
Ortenblad N, Mogensen M, Petersen I, Højlund K, Levin K, et al. (2005) Reduced insulin-mediated citrate synthase activity in cultured skeletal muscle cells from patients with type 2 diabetes: evidence for an intrinsic oxidative enzyme defect. Biochim Biophys Acta 1741: 206-214.
-
(2005)
Biochim Biophys Acta
, vol.1741
, pp. 206-214
-
-
Ortenblad, N.1
Mogensen, M.2
Petersen, I.3
Højlund, K.4
Levin, K.5
-
29
-
-
20044395441
-
Insulin resistance is associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects
-
Kashyap SR, Roman LJ, Lamont J, Masters BS, Bajaj M, et al. (2006) Insulin resistance is associated with impaired nitric oxide synthase activity in skeletal muscle of type 2 diabetic subjects. J Clin Endocrinol Metab 90: 1100-5.
-
(2006)
J Clin Endocrinol Metab
, vol.90
, pp. 1100-1105
-
-
Kashyap, S.R.1
Roman, L.J.2
Lamont, J.3
Masters, B.S.4
Bajaj, M.5
-
30
-
-
78049428301
-
A liver-derived secretory protein, selenoprotein P, causes insulin resistance
-
Misu H, Takamura T, Takayama H, Hayashi H, Matsuzawa-Nagata N, et al. (2010) A liver-derived secretory protein, selenoprotein P, causes insulin resistance. Cell Metab 2: 483-495.
-
(2010)
Cell Metab
, vol.2
, pp. 483-495
-
-
Misu, H.1
Takamura, T.2
Takayama, H.3
Hayashi, H.4
Matsuzawa-Nagata, N.5
-
31
-
-
37449020075
-
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, et al. (2008) Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 7: 45-56.
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
-
32
-
-
69249113803
-
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control
-
Noland RC, Koves TR, Seiler SE, Lum H, Lust RM, et al. (2009) Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. J Biol Chem 284: 22840-22852.
-
(2009)
J Biol Chem
, vol.284
, pp. 22840-22852
-
-
Noland, R.C.1
Koves, T.R.2
Seiler, S.E.3
Lum, H.4
Lust, R.M.5
-
33
-
-
66749094133
-
Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women
-
Adams SH, Hoppel CL, Lok KH, Zhao L, Wong SW, et al. (2009) Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women. J Nutr 139: 1073-1081.
-
(2009)
J Nutr
, vol.139
, pp. 1073-1081
-
-
Adams, S.H.1
Hoppel, C.L.2
Lok, K.H.3
Zhao, L.4
Wong, S.W.5
-
34
-
-
79551492488
-
Insulin says NO to cardiovascular disease
-
Yu Q, Gao F, Ma XL, (2011) Insulin says NO to cardiovascular disease. Cardiovasc Res 89: 516-524.
-
(2011)
Cardiovasc Res
, vol.89
, pp. 516-524
-
-
Yu, Q.1
Gao, F.2
Ma, X.L.3
-
35
-
-
77954512283
-
Periadventitial adipose tissue promotes endothelial dysfunction via oxidative stress in diet-induced obese C57Bl/6 mice
-
Ketonen J, Shi J, Martonen E, Mervaala E, (2010) Periadventitial adipose tissue promotes endothelial dysfunction via oxidative stress in diet-induced obese C57Bl/6 mice. Circ J 74: 1479-1487.
-
(2010)
Circ J
, vol.74
, pp. 1479-1487
-
-
Ketonen, J.1
Shi, J.2
Martonen, E.3
Mervaala, E.4
-
36
-
-
20444457010
-
Diabetes induces endothelial dysfunction but does not increase neointimal formation in high-fat diet fed C57BL/6J mice
-
Molnar J, Yu S, Mzhavia N, Pau C, Chereshnev I, et al. (2005) Diabetes induces endothelial dysfunction but does not increase neointimal formation in high-fat diet fed C57BL/6J mice. Circ Res 96: 1178-1184.
-
(2005)
Circ Res
, vol.96
, pp. 1178-1184
-
-
Molnar, J.1
Yu, S.2
Mzhavia, N.3
Pau, C.4
Chereshnev, I.5
-
37
-
-
12444304192
-
Obesity and cardiac failure
-
Galinier M, Pathak A, Roncalli J, Massabuau P, (2005) Obesity and cardiac failure. Arch Mal Coeur Vaiss 98: 39-45.
-
(2005)
Arch Mal Coeur Vaiss
, vol.98
, pp. 39-45
-
-
Galinier, M.1
Pathak, A.2
Roncalli, J.3
Massabuau, P.4
-
38
-
-
54049155806
-
Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription
-
Fang CX, Dong F, Thomas DP, Ma H, He L, et al. (2008) Hypertrophic cardiomyopathy in high-fat diet-induced obesity: role of suppression of forkhead transcription factor and atrophy gene transcription. Am J Physiol Heart Circ Physiol 295: H1206-H1215.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Fang, C.X.1
Dong, F.2
Thomas, D.P.3
Ma, H.4
He, L.5
-
39
-
-
33745712694
-
Pioglitazone prevents cardiac remodeling in high-fat, high-calorie-induced Type 2 diabetes mellitus
-
Rodriguez WE, Joshua IJ, Falcone JC, Tyagi SC, (2006) Pioglitazone prevents cardiac remodeling in high-fat, high-calorie-induced Type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 291: H81-H87.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Rodriguez, W.E.1
Joshua, I.J.2
Falcone, J.C.3
Tyagi, S.C.4
-
40
-
-
68049136011
-
Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase
-
Ussher JR, Koves TR, Jaswal JS, Zhang L, Ilkayeva O, et al. (2009) Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. Diabetes 58: 1766-1775.
-
(2009)
Diabetes
, vol.58
, pp. 1766-1775
-
-
Ussher, J.R.1
Koves, T.R.2
Jaswal, J.S.3
Zhang, L.4
Ilkayeva, O.5
-
41
-
-
42649127056
-
Cardiac output and index in obese and non-obese patients using gated single photon emission computed tomography sestamibi perfusion imaging
-
Coffey JP, Hill JC, (2005) Cardiac output and index in obese and non-obese patients using gated single photon emission computed tomography sestamibi perfusion imaging. J HK Coll Radiol 8: 226-232.
-
(2005)
J HK Coll Radiol
, vol.8
, pp. 226-232
-
-
Coffey, J.P.1
Hill, J.C.2
-
42
-
-
79955421173
-
Propionyl-L-carnitine: an overview of its pharmacological effects and clinical applications
-
Mingorance C, Rodriguez-Rodriguez R, Justo ML, Herrera MD, Alvarez de Sotomayor M, (2011) Propionyl-L-carnitine: an overview of its pharmacological effects and clinical applications. Nutr Rev 69: 279-290.
-
(2011)
Nutr Rev
, vol.69
, pp. 279-290
-
-
Mingorance, C.1
Rodriguez-Rodriguez, R.2
Justo, M.L.3
Herrera, M.D.4
Alvarez de Sotomayor, M.5
-
43
-
-
0034066578
-
Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions
-
Calvani M, Reda E, Arrigoni-Martelli E, (2000) Regulation by carnitine of myocardial fatty acid and carbohydrate metabolism under normal and pathological conditions. Basic Res Cardiol 95: 75-83.
-
(2000)
Basic Res Cardiol
, vol.95
, pp. 75-83
-
-
Calvani, M.1
Reda, E.2
Arrigoni-Martelli, E.3
|