-
1
-
-
0026271025
-
The role of heat-shock proteins as molecular chaperones
-
Welch, W. J. (1991) The role of heat-shock proteins as molecular chaperones. Curr. Opin. Cell. Biol. 3, 1033-1038.
-
(1991)
Curr. Opin. Cell. Biol.
, vol.3
, pp. 1033-1038
-
-
Welch, W.J.1
-
2
-
-
0025777354
-
Heat shock, stress proteins, chaperones, and proteotoxicity
-
Hightower, L. E. (1991) Heat shock, stress proteins, chaperones, and proteotoxicity. Cell 66, 191-197.
-
(1991)
Cell
, vol.66
, pp. 191-197
-
-
Hightower, L.E.1
-
3
-
-
25844519550
-
HSP90 and the chaperoning of cancer
-
Whitesell, L. and Lindquist, S. L. (2005) HSP90 and the chaperoning of cancer. Nat. Rev. Cancer 5, 761-772.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 761-772
-
-
Whitesell, L.1
Lindquist, S.L.2
-
4
-
-
33746364784
-
Structure and mechanism of the Hsp90 molecular chaperone machinery
-
Pearl, L. H. and Prodromou, C. (2006) Structure and mechanism of the Hsp90 molecular chaperone machinery. Annu. Rev. Biochem. 75, 271-294.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 271-294
-
-
Pearl, L.H.1
Prodromou, C.2
-
5
-
-
0033057848
-
Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology
-
Feder, M. E. and Hofmann, G. E. (1999) Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. Annu. Rev. Physiol. 61, 243-282.
-
(1999)
Annu. Rev. Physiol.
, vol.61
, pp. 243-282
-
-
Feder, M.E.1
Hofmann, G.E.2
-
6
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: emerging mechanistic insights
-
Taipale, M., Jarosz, D. F. and Lindquist, S. (2010) HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat. Rev. Mol. Cell. Biol. 11, 515-528.
-
(2010)
Nat. Rev. Mol. Cell. Biol.
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
7
-
-
4143095430
-
Altered Hsp90 function in cancer: a unique therapeutic opportunity
-
Bagatell, R. and Whitesell, L. (2004) Altered Hsp90 function in cancer: a unique therapeutic opportunity. Mol. Cancer Ther. 3, 1021-1030.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 1021-1030
-
-
Bagatell, R.1
Whitesell, L.2
-
8
-
-
33646114761
-
Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation
-
Blagg, B. S. and Kerr, T. D. (2006) Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation. Med. Res. Rev. 26, 310-338.
-
(2006)
Med. Res. Rev.
, vol.26
, pp. 310-338
-
-
Blagg, B.S.1
Kerr, T.D.2
-
9
-
-
37649024109
-
Development and application of Hsp90 inhibitors
-
Solit, D. B. and Chiosis, G. (2008) Development and application of Hsp90 inhibitors. Drug Discov. Today 13, 38-43.
-
(2008)
Drug Discov. Today
, vol.13
, pp. 38-43
-
-
Solit, D.B.1
Chiosis, G.2
-
10
-
-
74849111762
-
Heat shock protein 90: inhibitors in clinical trials
-
Biamonte, M. A., Van de Water, R., Arndt, J. W., Scannevin, R. H., Perret, D. and Lee, W. C. (2010) Heat shock protein 90: inhibitors in clinical trials. J. Med. Chem. 53, 3-17.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 3-17
-
-
Biamonte, M.A.1
Van de Water, R.2
Arndt, J.W.3
Scannevin, R.H.4
Perret, D.5
Lee, W.C.6
-
11
-
-
28644443855
-
The HSP90 family of genes in the human genome: insights into their divergence and evolution
-
Chen, B., Piel, W. H., Gui, L., Bruford, E. and Monteiro, A. (2005) The HSP90 family of genes in the human genome: insights into their divergence and evolution. Genomics. 86, 627-637.
-
(2005)
Genomics
, vol.86
, pp. 627-637
-
-
Chen, B.1
Piel, W.H.2
Gui, L.3
Bruford, E.4
Monteiro, A.5
-
12
-
-
0028954475
-
Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor
-
Song, H. Y., Dunbar, J. D., Zhang, Y. X., Guo, D. and Donner, D. B. (1995) Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor. J. Biol. Chem. 270, 3574-3581.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3574-3581
-
-
Song, H.Y.1
Dunbar, J.D.2
Zhang, Y.X.3
Guo, D.4
Donner, D.B.5
-
13
-
-
0029760873
-
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock
-
Chen, C. F., Chen, Y., Dai, K., Chen, P. L., Riley, D. J. and Lee, W. H. (1996) A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. Mol. Cell. Biol. 16, 4691-4699.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4691-4699
-
-
Chen, C.F.1
Chen, Y.2
Dai, K.3
Chen, P.L.4
Riley, D.J.5
Lee, W.H.6
-
14
-
-
0034603178
-
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties
-
Felts, S. J., Owen, B. A., Nguyen, P., Trepel, J., Donner, D. B. and Toft, D. O. (2000) The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. J. Biol. Chem. 275, 3305-3312.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3305-3312
-
-
Felts, S.J.1
Owen, B.A.2
Nguyen, P.3
Trepel, J.4
Donner, D.B.5
Toft, D.O.6
-
15
-
-
45549104450
-
The ATPase cycle of the mitochondrial Hsp90 analog Trap1
-
Leskovar, A., Wegele, H., Werbeck, N. D., Buchner, J. and Reinstein, J. (2008) The ATPase cycle of the mitochondrial Hsp90 analog Trap1. J. Biol. Chem. 283, 11677-11688.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11677-11688
-
-
Leskovar, A.1
Wegele, H.2
Werbeck, N.D.3
Buchner, J.4
Reinstein, J.5
-
16
-
-
35348887850
-
Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network
-
Kang, B. H., Plescia, J., Dohi, T., Rosa, J., Doxsey, S. J. and Altieri, D. C. (2007) Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network. Cell 131, 257-270.
-
(2007)
Cell
, vol.131
, pp. 257-270
-
-
Kang, B.H.1
Plescia, J.2
Dohi, T.3
Rosa, J.4
Doxsey, S.J.5
Altieri, D.C.6
-
17
-
-
65649128567
-
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90
-
Kang, B. H., Plescia, J., Song, H. Y., Meli, M., Colombo, G., Beebe, K., Scroggins, B., Neckers, L. and Altieri, D. C. (2009) Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90. J. Clin. Invest. 119, 454-464.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 454-464
-
-
Kang, B.H.1
Plescia, J.2
Song, H.Y.3
Meli, M.4
Colombo, G.5
Beebe, K.6
Scroggins, B.7
Neckers, L.8
Altieri, D.C.9
-
18
-
-
78650517733
-
Common ground for protein translocation: access control for mitochondria and chloroplasts
-
Schleiff, E. and Becker, T. (2011) Common ground for protein translocation: access control for mitochondria and chloroplasts. Nat. Rev. Mol. Cell. Biol. 12, 48-59.
-
(2011)
Nat. Rev. Mol. Cell. Biol.
, vol.12
, pp. 48-59
-
-
Schleiff, E.1
Becker, T.2
-
19
-
-
0032718876
-
A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses
-
Simmons, A. D., Musy, M. M., Lopes, C. S., Hwang, L. Y., Yang, Y. P. and Lovett, M. (1999) A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses. Hum. Mol. Genet. 8, 2155-2164.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 2155-2164
-
-
Simmons, A.D.1
Musy, M.M.2
Lopes, C.S.3
Hwang, L.Y.4
Yang, Y.P.5
Lovett, M.6
-
20
-
-
33745475570
-
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60
-
Deocaris, C. C., Kaul, S. C. and Wadhwa, R. (2006) On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60. Cell Stress Chaperones 11, 116-128.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 116-128
-
-
Deocaris, C.C.1
Kaul, S.C.2
Wadhwa, R.3
-
21
-
-
77956216928
-
Reactive oxygen species: stuck in the middle of neurodegeneration
-
Patten, D. A., Germain, M., Kelly, M. A. and Slack, R. S. (2010) Reactive oxygen species: stuck in the middle of neurodegeneration. J. Alzheimers Dis. 20(Suppl 2), S357-367.
-
(2010)
J. Alzheimers Dis.
, vol.20
, Issue.SUPPL. 2
-
-
Patten, D.A.1
Germain, M.2
Kelly, M.A.3
Slack, R.S.4
-
22
-
-
79956199030
-
Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention?
-
Sotgia, F., Martinez-Outschoorn, U. E. and Lisanti, M. P. (2011) Mitochondrial oxidative stress drives tumor progression and metastasis: should we use antioxidants as a key component of cancer treatment and prevention? BMC Med. 9, 62.
-
(2011)
BMC Med
, vol.9
, pp. 62
-
-
Sotgia, F.1
Martinez-Outschoorn, U.E.2
Lisanti, M.P.3
-
23
-
-
5644259582
-
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin
-
Masuda, Y., Shima, G., Aiuchi, T., Horie, M., Hori, K., Nakajo, S., Kajimoto, S., Shibayama-Imazu, T. and Nakaya, K. (2004) Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin. J. Biol. Chem. 279, 42503-42515.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 42503-42515
-
-
Masuda, Y.1
Shima, G.2
Aiuchi, T.3
Horie, M.4
Hori, K.5
Nakajo, S.6
Kajimoto, S.7
Shibayama-Imazu, T.8
Nakaya, K.9
-
24
-
-
36248980938
-
Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis
-
Montesano Gesualdi, N., Chirico, G., Pirozzi, G., Costantino, E., Landriscina, M. and Esposito, F. (2007) Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis. Stress 10, 342-350.
-
(2007)
Stress
, vol.10
, pp. 342-350
-
-
Montesano Gesualdi, N.1
Chirico, G.2
Pirozzi, G.3
Costantino, E.4
Landriscina, M.5
Esposito, F.6
-
25
-
-
34547138950
-
Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis
-
Hua, G., Zhang, Q. and Fan, Z. (2007) Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis. J. Biol. Chem. 282, 20553-20560.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20553-20560
-
-
Hua, G.1
Zhang, Q.2
Fan, Z.3
-
26
-
-
33846426804
-
Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species
-
Im, C. N., Lee, J. S., Zheng, Y. and Seo, J. S. (2007) Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species. J. Cell. Biochem. 100, 474-486.
-
(2007)
J. Cell. Biochem.
, vol.100
, pp. 474-486
-
-
Im, C.N.1
Lee, J.S.2
Zheng, Y.3
Seo, J.S.4
-
27
-
-
79953317434
-
Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells
-
Siegelin, M. D., Dohi, T., Raskett, C. M., Orlowski, G. M., Powers, C. M., Gilbert, C. A., Ross, A. H., Plescia, J. and Altieri, D. C. (2011) Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells. J. Clin. Invest. 121, 1349-1360.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1349-1360
-
-
Siegelin, M.D.1
Dohi, T.2
Raskett, C.M.3
Orlowski, G.M.4
Powers, C.M.5
Gilbert, C.A.6
Ross, A.H.7
Plescia, J.8
Altieri, D.C.9
-
28
-
-
0013198976
-
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection
-
Mattson, M. P. and Kroemer, G. (2003) Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. Trends Mol. Med. 9, 196-205.
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 196-205
-
-
Mattson, M.P.1
Kroemer, G.2
-
29
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer, G., Galluzzi, L. and Brenner, C. (2007) Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
30
-
-
33748961353
-
Mitochondrial membrane permeability transition and cell death
-
Tsujimoto, Y., Nakagawa, T. and Shimizu, S. (2006) Mitochondrial membrane permeability transition and cell death. Biochim. Biophys. Acta. 1757, 1297-1300.
-
(2006)
Biochim. Biophys. Acta.
, vol.1757
, pp. 1297-1300
-
-
Tsujimoto, Y.1
Nakagawa, T.2
Shimizu, S.3
-
31
-
-
34247895697
-
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
-
Baines, C. P., Kaiser, R. A., Sheiko, T., Craigen, W. J. and Molkentin, J. D. (2007) Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat. Cell. Biol. 9, 550-555.
-
(2007)
Nat. Cell. Biol.
, vol.9
, pp. 550-555
-
-
Baines, C.P.1
Kaiser, R.A.2
Sheiko, T.3
Craigen, W.J.4
Molkentin, J.D.5
-
32
-
-
0842307483
-
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
-
Kokoszka, J. E., Waymire, K. G., Levy, S. E., Sligh, J. E., Cai, J., Jones, D. P., MacGregor, G. R. and Wallace, D. C. (2004) The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427, 461-465.
-
(2004)
Nature
, vol.427
, pp. 461-465
-
-
Kokoszka, J.E.1
Waymire, K.G.2
Levy, S.E.3
Sligh, J.E.4
Cai, J.5
Jones, D.P.6
MacGregor, G.R.7
Wallace, D.C.8
-
33
-
-
21244446551
-
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D
-
Basso, E., Fante, L., Fowlkes, J., Petronilli, V., Forte, M. A. and Bernardi, P. (2005) Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. J. Biol. Chem. 280, 18558-18561.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18558-18561
-
-
Basso, E.1
Fante, L.2
Fowlkes, J.3
Petronilli, V.4
Forte, M.A.5
Bernardi, P.6
-
34
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines, C. P., Kaiser, R. A., Purcell, N. H., Blair, N. S., Osinska, H., Hambleton, M. A., Brunskill, E. W., Sayen, M. R., Gottlieb, R. A., Dorn, G. W., Robbins, J. and Molkentin, J. D. (2005) Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434, 658-662.
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn, G.W.10
Robbins, J.11
Molkentin, J.D.12
-
35
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa, T., Shimizu, S., Watanabe, T., Yamaguchi, O., Otsu, K., Yamagata, H., Inohara, H., Kubo, T. and Tsujimoto, Y. (2005) Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434, 652-658.
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
36
-
-
0033565965
-
Import and processing of heart mitochondrial cyclophilin D
-
Johnson, N., Khan, A., Virji, S., Ward, J. M. and Crompton, M. (1999) Import and processing of heart mitochondrial cyclophilin D. Eur. J. Biochem. 263, 353-359.
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 353-359
-
-
Johnson, N.1
Khan, A.2
Virji, S.3
Ward, J.M.4
Crompton, M.5
-
37
-
-
70350568650
-
Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones
-
Kang, B. H. and Altieri, D. C. (2009) Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones. Oncogene 28, 3681-3688.
-
(2009)
Oncogene
, vol.28
, pp. 3681-3688
-
-
Kang, B.H.1
Altieri, D.C.2
-
38
-
-
0034724389
-
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
-
Coller, H. A., Grandori, C., Tamayo, P., Colbert, T., Lander, E. S., Eisenman, R. N. and Golub, T. R. (2000) Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc. Natl. Acad. Sci. U.S.A. 97, 3260-3265.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 3260-3265
-
-
Coller, H.A.1
Grandori, C.2
Tamayo, P.3
Colbert, T.4
Lander, E.S.5
Eisenman, R.N.6
Golub, T.R.7
-
39
-
-
77956840339
-
Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE
-
Putz, S. M., Vogiatzi, F., Stiewe, T. and Sickmann, A. (2010) Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE. Mol. Cancer 9, 254.
-
(2010)
Mol. Cancer
, vol.9
, pp. 254
-
-
Putz, S.M.1
Vogiatzi, F.2
Stiewe, T.3
Sickmann, A.4
-
40
-
-
73949083526
-
Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer
-
Leav, I., Plescia, J., Goel, H. L., Li, J., Jiang, Z., Cohen, R. J., Languino, L. R. and Altieri, D. C. (2010) Cytoprotective mitochondrial chaperone TRAP-1 as a novel molecular target in localized and metastatic prostate cancer. Am. J. Pathol. 176, 393-401.
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 393-401
-
-
Leav, I.1
Plescia, J.2
Goel, H.L.3
Li, J.4
Jiang, Z.5
Cohen, R.J.6
Languino, L.R.7
Altieri, D.C.8
-
41
-
-
79955757100
-
Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein
-
Kang, B. H., Xia, F., Pop, R., Dohi, T., Socolovsky, M. and Altieri, D. C. (2011) Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein. J. Biol. Chem. 286, 16758-16767.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 16758-16767
-
-
Kang, B.H.1
Xia, F.2
Pop, R.3
Dohi, T.4
Socolovsky, M.5
Altieri, D.C.6
-
42
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon, J. W., Olzmann, J. A., Chin, L. S. and Li, L. (2007) PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol. 5, e172.
-
(2007)
PLoS Biol
, vol.5
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.S.3
Li, L.4
-
43
-
-
77954945333
-
Targeting the dynamic HSP90 complex in cancer
-
Trepel, J., Mollapour, M., Giaccone, G. and Neckers, L. (2010) Targeting the dynamic HSP90 complex in cancer. Nat. Rev. Cancer 10, 537-549.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 537-549
-
-
Trepel, J.1
Mollapour, M.2
Giaccone, G.3
Neckers, L.4
-
44
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby, R. A. and Gillies, R. J. (2004) Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer 4, 891-899.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
45
-
-
67349088746
-
TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptosis in human colorectal carcinoma cells
-
Costantino, E., Maddalena, F., Calise, S., Piscazzi, A., Tirino, V., Fersini, A., Ambrosi, A., Neri, V., Esposito, F. and Landriscina, M. (2009) TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptosis in human colorectal carcinoma cells. Cancer Lett. 279, 39-46.
-
(2009)
Cancer Lett
, vol.279
, pp. 39-46
-
-
Costantino, E.1
Maddalena, F.2
Calise, S.3
Piscazzi, A.4
Tirino, V.5
Fersini, A.6
Ambrosi, A.7
Neri, V.8
Esposito, F.9
Landriscina, M.10
-
46
-
-
77955282115
-
Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases
-
Liu, D., Hu, J., Agorreta, J., Cesario, A., Zhang, Y., Harris, A. L., Gatter, K. and Pezzella, F. (2010) Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases. Cancer Lett. 296, 194-205.
-
(2010)
Cancer Lett
, vol.296
, pp. 194-205
-
-
Liu, D.1
Hu, J.2
Agorreta, J.3
Cesario, A.4
Zhang, Y.5
Harris, A.L.6
Gatter, K.7
Pezzella, F.8
-
47
-
-
79956220325
-
Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum
-
Takemoto, K., Miyata, S., Takamura, H., Katayama, T. and Tohyama, M. (2011) Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum. Neurochem. Int. 58, 880-887.
-
(2011)
Neurochem. Int.
, vol.58
, pp. 880-887
-
-
Takemoto, K.1
Miyata, S.2
Takamura, H.3
Katayama, T.4
Tohyama, M.5
-
48
-
-
77957554723
-
Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer
-
Kang, B. H., Siegelin, M. D., Plescia, J., Raskett, C. M., Garlick, D. S., Dohi, T., Lian, J. B., Stein, G. S., Languino, L. R. and Altieri, D. C. (2010) Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer. Clin. Cancer Res. 16, 4779-4788.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 4779-4788
-
-
Kang, B.H.1
Siegelin, M.D.2
Plescia, J.3
Raskett, C.M.4
Garlick, D.S.5
Dohi, T.6
Lian, J.B.7
Stein, G.S.8
Languino, L.R.9
Altieri, D.C.10
-
49
-
-
79951673830
-
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
-
Kang, B. H., Tavecchio, M., Goel, H. L., Hsieh, C. C., Garlick, D. S., Raskett, C. M., Lian, J. B., Stein, G. S., Languino, L. R. and Altieri, D. C. (2011) Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease. Br. J. Cancer 104, 629-634.
-
(2011)
Br. J. Cancer
, vol.104
, pp. 629-634
-
-
Kang, B.H.1
Tavecchio, M.2
Goel, H.L.3
Hsieh, C.C.4
Garlick, D.S.5
Raskett, C.M.6
Lian, J.B.7
Stein, G.S.8
Languino, L.R.9
Altieri, D.C.10
-
50
-
-
21144437911
-
Rational design of shepherdin, a novel anticancer agent
-
Plescia, J., Salz, W., Xia, F., Pennati, M., Zaffaroni, N., Daidone, M. G., Meli, M., Dohi, T., Fortugno, P., Nefedova, Y., Gabrilovich, D. I., Colombo, G. and Altieri, D. C. (2005) Rational design of shepherdin, a novel anticancer agent. Cancer Cell 7, 457-468.
-
(2005)
Cancer Cell
, vol.7
, pp. 457-468
-
-
Plescia, J.1
Salz, W.2
Xia, F.3
Pennati, M.4
Zaffaroni, N.5
Daidone, M.G.6
Meli, M.7
Dohi, T.8
Fortugno, P.9
Nefedova, Y.10
Gabrilovich, D.I.11
Colombo, G.12
Altieri, D.C.13
-
51
-
-
77953131908
-
Targeting mitochondria for cancer therapy
-
Fulda, S., Galluzzi, L. and Kroemer, G. (2010) Targeting mitochondria for cancer therapy. Nat. Rev. Drug Discov. 9, 447-464.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 447-464
-
-
Fulda, S.1
Galluzzi, L.2
Kroemer, G.3
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