Involvement of organic anion-transporting polypeptides in the hepatic uptake of dioscin in rats and humanss

Drug Metabolism and Disposition

Volumn 41, Issue 5, 2013, Pages 994-1003

  Zhang, Aijie ^a   Wang, Changyuan ^a,b   Liu, Qi ^a,b   Meng, Qiang ^a,b   Peng, Jinyong ^a,b,c   Sun, Huijun ^a,b   Ma, Xiaochi ^a,b,c   Huo, Xiaokui ^a   Liu, Kexin ^a,b,c  

^a Department of Clinical Pharmacology College of Pharmacy   (China)

^b Provincial Key Laboratory for Pharmacokinetics and Transport   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOHIPPURIC ACID; CYCLOSPORIN A; DIGOXIN; DIOSCIN; EPIGALLOCATECHIN GALLATE; GLYCYRRHIZIC ACID; IBUPROFEN; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 1A1; ORGANIC ANION TRANSPORTER 1A4; ORGANIC ANION TRANSPORTER 1B1; ORGANIC ANION TRANSPORTER 1B2; ORGANIC ANION TRANSPORTER 1B3; PLANT MEDICINAL PRODUCT; RIFAMPICIN; TELMISARTAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TRANSPORT; DRUG UPTAKE; EMBRYO; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER PERFUSION; MALE; MDCK CELL; NONHUMAN; PRIORITY JOURNAL; RAT; TEMPERATURE DEPENDENCE;

ANIMALS; DIOSGENIN; HEK293 CELLS; HUMANS; LIVER; MALE; ORGANIC ANION TRANSPORTERS; RATS; RATS, WISTAR;

RATTUS;

EID: 84876775271     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.049452     Document Type: Article

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