Comparative inhibitory effects of different compounds on rat Oatp1 (Slc21a1)- and Oatp2 (Slc21a5)-mediated transport

Pharmaceutical Research

Volumn 19, Issue 2, 2002, Pages 147-153

  Shitara, Y ^a   Sugiyama, D ^b   Kusuhara, H ^b,c   Kato, Y ^b,c   Abe, T ^d   Meier, P J ^e   Itoh, T ^a   Sugiyama, Y ^b,c  

^a KITASATO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Hepatic transport; Oatp; Organic anion transporter

Indexed keywords

2 OXOGLUTARIC ACID; 4 AMINOHIPPURIC ACID; CIMETIDINE; CORTICOSTERONE; CYCLOSPORIN A; DEOXYCORTICOSTERONE; DIGOXIN; ESTRADIOL 17 GLUCURONIDE; IBUPROFEN; INDOMETACIN; KETOPROFEN; METHOTREXATE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PENICILLIN G; POLYPEPTIDE; PROPIONIC ACID; PROTEIN OATP1; PROTEIN OATP2; QUINIDINE; RIFAMPICIN; TOLBUTAMIDE; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TRANSPORT; DRUG UPTAKE; LIVER CELL; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ALGORITHMS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBIOTICS, ANTITUBERCULAR; ANTIMALARIALS; BIOLOGICAL TRANSPORT, ACTIVE; DIGOXIN; ENZYME INHIBITORS; ESTRADIOL; IBUPROFEN; LLC-PK1 CELLS; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; ORGANIC CATION TRANSPORT PROTEINS; QUINIDINE; QUININE; RATS; RIFAMPIN; SWINE;

EID: 0036175452     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014264614637     Document Type: Article

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