Hydrogen sulfide prevents hyperoxia-induced lung injury by downregulating reactive oxygen species formation and angiopoietin-2 release

Current Pharmaceutical Design

Volumn 19, Issue 15, 2013, Pages 2715-2721

  Faller, Simone ^a   Spassov, Sashko G ^a   Zimmermann, Kornelia K ^a   Ryter, Stefan W ^b   Buerkle, Hartmut ^a   Loop, Torsten ^a   Schmidt, Rene ^a   Strosing, Karl M ^a   Hoetzel, Alexander ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Angiopoietin 2; Hydrogen sulfide; Hyperoxia; Hyperoxia induced acute lung injury; Organ protection; Reactive oxygen species

Indexed keywords

ANGIOPOIETIN 2; HYDROGEN SULFIDE; REACTIVE OXYGEN METABOLITE; THEOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HYPEROXIA INDUCED ACUTE LUNG INJURY; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG ENDOTHELIUM; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANGIOPOIETIN-2; ANIMALS; DOWN-REGULATION; HUMANS; HYDROGEN SULFIDE; HYPEROXIA; LUNG INJURY; MICE; MICE, INBRED C57BL; REACTIVE OXYGEN SPECIES;

EID: 84876740771     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319150006     Document Type: Article

References (43)

1. Altemeier WA, Sinclair SE. Hyperoxia in the intensive care unit: why more is not always better. Curr Opin Crit Care 2007; 13: (1), 73-8.
2. Bhandari V, Choo-Wing R, Lee CG, et al. Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med 2006; 12: (11), 1286-93.
3. Bhandari V, Choo-Wing R, Harijith A, et al. Increased Hyperoxia-Induced Lung Injury in Nitric Oxide Synthase 2 Null Mice is Mediated via Angiopoietin 2. Am J Respir Cell Mol Biol 2012.
4. Harijith A, Choo-Wing R, Cataltepe S, et al. A role for matrix metalloproteinase 9 in IFNgamma-mediated injury in developing lungs: relevance to bronchopulmonary dysplasia. Am J Respir Cell Mol Biol 2011; 44: (5), 621-30.
5. Lang YD, Hung CL, Wu TY, Wang LF, Chen CM. The reninangiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts. Free Radic Biol Med 2010; 49: (1), 88-95.
6. Whiteman M, Le Trionnaire S, Chopra M, Fox B, Whatmore J. Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools. Clin Sci (Lond) 2011; 121: (11), 459-88.
7. Faller S, Ryter SW, Choi AM, Loop T, Schmidt R, Hoetzel A. Inhaled hydrogen sulfide protects against ventilator-induced lung injury. Anesthesiology 2010; 113: (1), 104-15.
8. Li L, Rossoni G, Sparatore A, Lee LC, Del Soldato P, Moore PK. Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative. Free Radic Biol Med 2007; 42: (5), 706-19.
9. Spiller F, Orrico MI, Nascimento DC, et al. Hydrogen sulfide improves neutrophil migration and survival in sepsis via K+ATP channel activation. Am J Respir Crit Care Med 2010; 182: (3), 360-8.
10. Biermann J, Lagreze WA, Schallner N, Schwer CI, Goebel U. Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury. Mol Vis 2011; 17: 1275-86.
11. Tang XQ, Yang CT, Chen J, et al. Effect of hydrogen sulphide on beta-amyloid-induced damage in PC12 cells. Clin Exp Pharmacol Physiol 2008; 35: (2), 180-6.
12. Yin WL, He JQ, Hu B, Jiang ZS, Tang XQ. Hydrogen sulfide inhibits MPP(+)-induced apoptosis in PC12 cells. Life Sci 2009; 85: (7-8), 269-75.
13. Chen ZF, Zhao B, Tang XY, et al. Hydrogen sulfide regulates vascular endoplasmic reticulum stress in apolipoprotein E knockout mice. Chin Med J (Engl) 2011; 124: (21), 3460-7.
14. Chen SL, Yang CT, Yang ZL, et al. Hydrogen sulphide protects H9c2 cells against chemical hypoxia-induced injury. Clin Exp Pharmacol Physiol 2010; 37: (3), 316-21.
15. Yang C, Yang Z, Zhang M, et al. Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-kappaB/COX-2 pathway. PLoS One 2011; 6: (7), e21971.
16. Bhatia M, Zhi L, Zhang H, Ng SW, Moore PK. Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice. Am J Physiol Lung Cell Mol Physiol 2006; 291: (5), L896-L904.
17. Faller S, Foeckler M, Strosing KM, et al. Kinetic effects of carbon monoxide inhalation on tissue protection in ventilator-induced lung injury. Lab Invest 2012.
18. Crumpton TL, Seidler FJ, Slotkin TA. Generation of reactive oxygen species by xanthine derivatives in MDA-MB-231 human breast cancer cells. Breast Cancer Res Treat 2001; 66: (2), 143-6.
19. Kaneko M, Suzuki K, Furui H, Takagi K, Satake T. Comparison of theophylline and enprofylline effects on human neutrophil superoxide production. Clin Exp Pharmacol Physiol 1990; 17: (12), 849-59.
20. Zaher TE, Miller EJ, Morrow DM, Javdan M, Mantell LL. Hyperoxia-induced signal transduction pathways in pulmonary epithelial cells. Free Radic Biol Med 2007; 42 (7): 897-908.
21. Li L, Rose P, Moore PK. Hydrogen sulfide and cell signaling. Annu Rev Pharmacol Toxicol 2011; 51: 169-87.
22. Esechie A, Kiss L, Olah G, et al. Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation. Clin Sci (Lond) 2008; 115: (3), 91-7.
23. Li T, Zhao B, Wang C, et al. Regulatory effects of hydrogen sulfide on IL-6, IL-8 and IL-10 levels in the plasma and pulmonary tissue of rats with acute lung injury. Exp Biol Med (Maywood) 2008; 233: (9), 1081-7.
24. Chai W, Wang Y, Lin JY, et al. Exogenous Hydrogen Sulfide Protects Against Traumatic Hemorrhagic Shock Via Attenuation of Oxidative Stress. J Surg Res 2011.
25. Sodha NR, Clements RT, Feng J, et al. Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury. J Thorac Cardiovasc Surg 2009; 138: (4), 977-84.
26. Shi YX, Chen Y, Zhu YZ, et al. Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2007; 293: (4), H2093-H2100.
27. Geng B, Chang L, Pan C, et al. Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol. Biochem Biophys Res Commun 2004; 318: (3), 756-63.
28. Kimura Y, Kimura H. Hydrogen sulfide protects neurons from oxidative stress. FASEB J 2004; 18: (10), 1165-7.
29. Parinandi NL, Kleinberg MA, Usatyuk PV, et al. Hyperoxiainduced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. Am J Physiol Lung Cell Mol Physiol 2003; 284: (1), L26-L38.
30. Zhang X, Shan P, Sasidhar M, et al. Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium. Am J Respir Cell Mol Biol 2003; 28: (3), 305-15.
31. Lee PJ, Alam J, Sylvester SL, Inamdar N, Otterbein L, Choi AM. Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. Am J Respir Cell Mol Biol 1996; 14: (6), 556-68.
32. Wong HR, Menendez IY, Ryan MA, Denenberg AG, Wispe JR. Increased expression of heat shock protein-70 protects A549 cells against hyperoxia. Am J Physiol 1998; 275: (4 Pt 1), L836-L841.
33. Fiedler U, Augustin HG. Angiopoietins: a link between angiogenesis and inflammation. Trends Immunol 2006; 27: (12), 552-8.
34. Chen H, Zhang L, Jin Z, et al. Anti-apoptotic PTD-FNK protein suppresses lipopolysaccharide-induced acute lung injury in rats. Exp Mol Pathol 2007; 83: (3), 377-84.
35. Kolliputi N, Waxman AB. IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation. Am J Physiol Lung Cell Mol Physiol 2009; 297: (1), L6-16.
36. Witzenrath M, Gutbier B, Hocke AC, et al. Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia. Crit Care Med 2006; 34: (7), 1947-54.
37. Barlos D, Deitch EA, Watkins AC, et al. Trauma-hemorrhagic shock-induced pulmonary epithelial and endothelial cell injury utilizes different programmed cell death signaling pathways. Am J Physiol Lung Cell Mol Physiol 2009; 296: (3), L404-L417.
38. Park HJ, Jeon BT, Kim HC, et al. Aged red garlic extract reduces lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages and acute pulmonary inflammation through haeme oxygenase-1 induction. Acta Physiol (Oxf) 2012; 205(1): 61-70.
39. Shelton JL, Wang L, Cepinskas G, et al. Albumin leak across human pulmonary microvascular vs. umbilical vein endothelial cells under septic conditions. Microvasc Res 2006; 71(1): 40-7.
40. Fiedler U, Scharpfenecker M, Koidl S, et al. The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies. Blood 2004; 103(11): 4150-6.
41. Wu JA, Johnson BL, Chen Y, Ha CT, Dveksler GS. Murine pregnancy-specific glycoprotein 23 induces the proangiogenic factors transforming-growth factor beta 1 and vascular endothelial growth factor a in cell types involved in vascular remodeling in pregnancy. Biol Reprod 2008; 79(6): 1054-61.
42. Osborne NN, Ji D, Majid AS, Del Soldata P, Sparatore A. Glutamate oxidative injury to RGC-5 cells in culture is necrostatin sensitive and blunted by a hydrogen sulfide (H2S)-releasing derivative of aspirin (ACS14). Neurochem Int 2012; 60(4): 365-78.
43. Tyagi N, Moshal KS, Sen U, et al. H2S protects against methionine-induced oxidative stress in brain endothelial cells. Antioxid Redox Signal 2009; 11 (1): 25-33.