Generation of reactive oxygen species by xanthine derivatives in MDA-MB-231 human breast cancer cells

Breast Cancer Research and Treatment

Volumn 66, Issue 2, 2001, Pages 143-146

  Crumpton, T L ^a   Seidler, F J ^a   Slotkin, T A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Oxidative stress; Reactive oxygen; Sodium nitroprusside; Theophylline; Xanthine derivatives

Indexed keywords

ANTINEOPLASTIC AGENT; FLUORESCENT DYE; ISOBUTYLMETHYLXANTHINE; NITROPRUSSIDE SODIUM; OXIDIZING AGENT; PHOSPHODIESTERASE; REACTIVE OXYGEN METABOLITE; THEOPHYLLINE; XANTHINE DERIVATIVE;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL COUNT; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; SENSITIZATION;

1-METHYL-3-ISOBUTYLXANTHINE; BREAST NEOPLASMS; FEMALE; HUMANS; PHOSPHODIESTERASE INHIBITORS; REACTIVE OXYGEN SPECIES; THEOPHYLLINE; TUMOR CELLS, CULTURED;

EID: 0035004902     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010603816003     Document Type: Article

References (18)

1. β-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells
2. Antimitotic and cytotoxic effects of theophylline in MDA-MB-231 human breast cancer cells
3. Theophylline induced differentiation provides direct evidence for the deregulation of c-myc in Burkitt's lymphoma and suggests participation of immunoglobulin enhancer sequences
4. Effects of dibutyryl cyclic adenosine 3′:5′-monophosphate on the growth of cultured human small-cell lung carcinoma and the specific cellular activity of L-dopa decarboxylase
5. Inhibition of melanoma pulmonary metastasis by methylxanthines due to decreased invasion and proliferation
6. A new generation of phosphodiesterase inhibitors: Multiple molecular forms of phosphodiesterase and the potential for drug selectivity
7. Effect of prolactin on growth and the estrogen receptor level of human breast cancer cells (MCF-7)
8. The effect of papaverine on morphologic differentiation, proliferation and invasive potential of human prostatic cancer LNCaP cells
9. A cautionary note: The actions of adenosine agonists and antagonists may be reversed under certain conditions in primary cultures
10. Nitric oxide, peroxynitrite and nitroso-compounds formation by ultraviolet A (UVA) irradiated human squamous cell carcinoma: Potential role of nitric oxide in cancer prognosis
11. Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: Possible implication for involvement of hydroxyl radicals
12. Nitric oxide and oxygen radicals in infection, inflammation, and cancer
13. A novel cancer therapy based on oxygen radicals
14. Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?
15. Monitoring intracellular nitric oxide formation by chlorofluorescein in neuronal cells
16. Therapeutic potential of isozyme-selective phosphodiesterase inhibitors in the treatment of asthma
17. 3 adenosine receptor activation and its suppression by isoproterenol
18. Alkylxanthine adenosine antagonists and epileptiform activity in rat hippocampal slices in vitro