Glutamate oxidative injury to RGC-5 cells in culture is necrostatin sensitive and blunted by a hydrogen sulfide (H 2S)-releasing derivative of aspirin (ACS14)

Neurochemistry International

Volumn 60, Issue 4, 2012, Pages 365-378

  Osborne, Neville N ^a,b,g   Ji, Dan ^a,c   Majid, Aman Shah Abdul ^a,d   Del Soldata, Piero ^e   Sparatore, Anna ^f  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Fundacion de Investigacion Oftalmologica   (Spain)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

^e GTC Pharma   (Italy)

^f UNIVERSITY OF MILAN   (Italy)

^g Cátedra de Biomedicina Department of Biomedicine   (Italy)

Author keywords

ACS14; Aspirin; Glutamate toxicity; Hydrogen sulphide; Necrostatin; Neuroprotection; Oxidative stress

Indexed keywords

2 ACETYLOXYBENZOIC ACID 4 (3 THIOXO 3H 1,2 DITHIOL 5 YL)PHENYL ESTER; ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID DERIVATIVE; APOPTOSIS INDUCING FACTOR; BUTHIONINE SULFOXIMINE; CASPASE INHIBITOR; DNA; GLIBENCLAMIDE; GLUTAMIC ACID; GLUTATHIONE; HEME OXYGENASE 1; HYDROGEN SULFIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NECROSTATIN 1; PHOSPHATIDYLSERINE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RESAZURIN; STATIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CELL KILLING; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ASPIRIN; BASE SEQUENCE; CELL LINE, TRANSFORMED; DNA PRIMERS; GLUTAMIC ACID; GLUTATHIONE; HYDROGEN SULFIDE; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; INDOLES; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES;

EID: 84857015561     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.01.015     Document Type: Article

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