메뉴 건너뛰기




Volumn 70, Issue 9, 2013, Pages 1623-1636

NSBP-1 mediates the effects of cholesterol on insulin/IGF-1 signaling in Caenorhabditis elegans

Author keywords

C. elegans; Cholesterol; Cholesterol binding protein; D2096.8; DAF 16; Insulin IGF 1 signaling

Indexed keywords

BINDING PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; CHOLESTEROL; INSULIN; NEMATODE STEROL BINDING PROTEIN 1; PROTEIN KINASE B; SOMATOMEDIN C; TRANSCRIPTION FACTOR DAF 16; UNCLASSIFIED DRUG;

EID: 84876694690     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1221-0     Document Type: Article
Times cited : (13)

References (67)
  • 2
    • 30344473341 scopus 로고    scopus 로고
    • Protein sensors for membrane sterols
    • DOI 10.1016/j.cell.2005.12.022, PII S0092867405014637
    • Goldstein JL, DeBose-Boyd RA, Brown MS (2006) Protein sensors for membrane sterols. Cell 124(1):35-46. doi: 10.1016/j.cell.2005.12.022 (Pubitemid 43069308)
    • (2006) Cell , vol.124 , Issue.1 , pp. 35-36
    • Goldstein, J.L.1    DeBose-Boyd, R.A.2    Brown, M.S.3
  • 3
    • 33750318425 scopus 로고    scopus 로고
    • Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport
    • DOI 10.1074/jbc.M602765200
    • Cheruku SR, Xu Z, Dutia R, Lobel P, Storch J (2006) Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport. J Biol Chem 281(42):31594-31604. doi: 10.1074/jbc.M602765200 (Pubitemid 46041425)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.42 , pp. 31594-31604
    • Cheruku, S.R.1    Xu, Z.2    Dutia, R.3    Lobel, P.4    Storch, J.5
  • 4
    • 0019415955 scopus 로고
    • Serum reserve cholesterol binding capacity (SRCBC): The relative importance of different lipoprotein classes
    • Borresen AL, Berg K (1981) Serum reserve cholesterol binding capacity (SRCBC): the relative importance of different lipoprotein classes. Artery 9(2):96-119 (Pubitemid 11034147)
    • (1981) Artery , vol.9 , Issue.2 , pp. 96-119
    • Borresen, A.L.1    Berg, K.2
  • 5
    • 0033147405 scopus 로고    scopus 로고
    • Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans
    • Scheel J, Srinivasan J, Honnert U, Henske A, Kurzchalia TV (1999) Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans. Nat Cell Biol 1(2):127-129. doi: 10.1038/10100 (Pubitemid 129501956)
    • (1999) Nature Cell Biology , vol.1 , Issue.2 , pp. 127-129
    • Scheel, J.1    Srinivasan, J.2    Honnert, U.3    Henske, A.4    Kurzchalia, T.V.5
  • 6
    • 8844266121 scopus 로고    scopus 로고
    • Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16
    • DOI 10.1371/journal.pbio.0020280
    • Matyash V, Entchev EV, Mende F, Wilsch-Brauninger M, Thiele C, Schmidt AW, Knolker HJ, Ward S, Kurzchalia TV (2004) Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. PLoS Biol 2(10):e280. doi: 10.1371/journal.pbio.0020280 (Pubitemid 39532917)
    • (2004) PLoS Biology , vol.2 , Issue.10
    • Matyash, V.1    Entchev, E.V.2    Mende, F.3    Wilsch-Brauninger, M.4    Thiele, C.5    Schmidt, A.W.6    Knolker, H.-J.7    Ward, S.8    Kurzchalia, T.V.9
  • 7
    • 0036159054 scopus 로고    scopus 로고
    • Role of cholesterol in germ-line development of Caenorhabditis elegans
    • DOI 10.1002/mrd.10099
    • Shim YH, Chun JH, Lee EY, Paik YK (2002) Role of cholesterol in germ-line development of Caenorhabditis elegans. Mol Reprod Dev 61(3):358-366. doi: 10.1002/mrd.10099 (Pubitemid 34117053)
    • (2002) Molecular Reproduction and Development , vol.61 , Issue.3 , pp. 358-366
    • Shim, Y.-H.1    Chun, J.H.2    Lee, E.-Y.3    Paik, Y.-K.4
  • 8
    • 0033000965 scopus 로고    scopus 로고
    • A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting
    • Yochem J, Tuck S, Greenwald I, Han M (1999) A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting. Development 126(3):597-606 (Pubitemid 29082046)
    • (1999) Development , vol.126 , Issue.3 , pp. 597-606
    • Yochem, J.1    Tuck, S.2    Greenwald, I.3    Min, H.4
  • 9
    • 33747184525 scopus 로고    scopus 로고
    • C. elegans: An invaluable model organism for the proteomics studies of the cholesterol-mediated signaling pathway
    • DOI 10.1586/14789450.3.4.439
    • Paik YK, Jeong SK, Lee EY, Jeong PY, Shim YH (2006) C. elegans: an invaluable model organism for the proteomics studies of the cholesterol-mediated signaling pathway. Expert Rev Proteomics 3(4):439-453. doi: 10.1586/14789450.3.4.439 (Pubitemid 44231986)
    • (2006) Expert Review of Proteomics , vol.3 , Issue.4 , pp. 439-453
    • Paik, Y.-K.1    Jeong, S.-K.2    Lee, E.-Y.3    Jeong, P.-Y.4    Shim, Y.-H.5
  • 10
    • 79953214582 scopus 로고    scopus 로고
    • A potential biochemical mechanism underlying the influence of sterol deprivation stress on Caenorhabditis elegans longevity
    • 10.1074/jbc.M110.189183 21186286 10.1074/jbc.M110.189183 1:CAS:528:DC%2BC3MXisVyqs7k%3D
    • Cheong MC, Na K, Kim H, Jeong SK, Joo HJ, Chitwood DJ, Paik YK (2011) A potential biochemical mechanism underlying the influence of sterol deprivation stress on Caenorhabditis elegans longevity. J Biol Chem 286(9):7248-7256. doi: 10.1074/jbc.M110.189183
    • (2011) J Biol Chem , vol.286 , Issue.9 , pp. 7248-7256
    • Cheong, M.C.1    Na, K.2    Kim, H.3    Jeong, S.K.4    Joo, H.J.5    Chitwood, D.J.6    Paik, Y.K.7
  • 11
    • 0035656274 scopus 로고    scopus 로고
    • A Hormonal Signaling Pathway Influencing C. elegans Metabolism, Reproductive Development, and Life Span
    • DOI 10.1016/S1534-5807(01)00085-5, PII S1534580701000855
    • Gerisch B, Weitzel C, Kober-Eisermann C, Rottiers V, Antebi A (2001) A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Devel Cell 1(6):841-851 (Pubitemid 33586137)
    • (2001) Developmental Cell , vol.1 , Issue.6 , pp. 841-851
    • Gerisch, B.1    Weitzel, C.2    Kober-Eisermann, C.3    Rottiers, V.4    Antebi, A.5
  • 12
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • DOI 10.1038/414799a
    • Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414(6865):799-806. doi: 10.1038/414799a (Pubitemid 34000783)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 13
    • 3042698404 scopus 로고    scopus 로고
    • Lilly lecture 2003: The struggle for mastery in insulin action: From triumvirate to republic
    • DOI 10.2337/diabetes.53.7.1633
    • Accili D (2004) Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic. Diabetes 53 (7):1633-1642. pii:53/7/1633 (Pubitemid 38857019)
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1633-1642
    • Accili, D.1
  • 14
    • 52449086907 scopus 로고    scopus 로고
    • The insulin paradox: Aging, proteotoxicity and neurodegeneration
    • 10.1038/nrn2474 18769445 10.1038/nrn2474 1:CAS:528:DC%2BD1cXhtFeit7fM
    • Cohen E, Dillin A (2008) The insulin paradox: aging, proteotoxicity and neurodegeneration. Nat Rev Neurosci 9(10):759-767. doi: 10.1038/nrn2474
    • (2008) Nat Rev Neurosci , vol.9 , Issue.10 , pp. 759-767
    • Cohen, E.1    Dillin, A.2
  • 15
    • 34848911606 scopus 로고    scopus 로고
    • Genetics of aging in Caenorhabditis elegans
    • DOI 10.1371/journal.pgen.0030129
    • Antebi A (2007) Genetics of aging in Caenorhabditis elegans. PLoS Genet 3(9):1565-1571. doi: 10.1371/journal.pgen.0030129 (Pubitemid 47510250)
    • (2007) PLoS Genetics , vol.3 , Issue.9 , pp. 1565-1571
    • Antebi, A.1
  • 16
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: Insights from long-lived mutants
    • DOI 10.1016/j.cell.2005.02.002
    • Kenyon C (2005) The plasticity of aging: insights from long-lived mutants. Cell 120(4):449-460. doi: 10.1016/j.cell.2005.02.002 (Pubitemid 40269760)
    • (2005) Cell , vol.120 , Issue.4 , pp. 449-460
    • Kenyon, C.1
  • 17
    • 0030813398 scopus 로고    scopus 로고
    • Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • DOI 10.1126/science.277.5328.942
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277(5328):942-946 (Pubitemid 27366677)
    • (1997) Science , vol.277 , Issue.5328 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 18
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • DOI 10.1038/382536a0
    • Morris JZ, Tissenbaum HA, Ruvkun G (1996) A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382(6591):536-539. doi: 10.1038/382536a0 (Pubitemid 26260694)
    • (1996) Nature , vol.382 , Issue.6591 , pp. 536-539
    • Morris, J.Z.1    Tissenbaum, H.A.2    Ruvkun, G.3
  • 19
    • 11144355021 scopus 로고    scopus 로고
    • C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span
    • DOI 10.1016/S1534-5807(04)00095-4, PII S1534580704000954
    • Hertweck M, Gobel C, Baumeister R (2004) C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Dev Cell 6 (4):577-588. pii:S1534580704000954 (Pubitemid 38456185)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 577-588
    • Hertweck, M.1    Gobel, C.2    Baumeister, R.3
  • 20
    • 0033151613 scopus 로고    scopus 로고
    • A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
    • Paradis S, Ailion M, Toker A, Thomas JH, Ruvkun G (1999) A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. Genes Dev 13(11):1438-1452 (Pubitemid 29270248)
    • (1999) Genes and Development , vol.13 , Issue.11 , pp. 1438-1452
    • Paradis, S.1    Ailion, M.2    Toker, A.3    Thomas, J.H.4    Ruvkun, G.5
  • 21
    • 0032529189 scopus 로고    scopus 로고
    • Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from age-1 PI3 kinase to the DAF-16 transcription factor
    • Paradis S, Ruvkun G (1998) Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes Dev 12(16):2488-2498 (Pubitemid 28406952)
    • (1998) Genes and Development , vol.12 , Issue.16 , pp. 2488-2498
    • Paradis, S.1    Ruvkun, G.2
  • 22
    • 0030657540 scopus 로고    scopus 로고
    • Daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • DOI 10.1126/science.278.5341.1319
    • Lin K, Dorman JB, Rodan A, Kenyon C (1997) daf-16: an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278(5341):1319-1322 (Pubitemid 27495748)
    • (1997) Science , vol.278 , Issue.5341 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 23
    • 0030659557 scopus 로고    scopus 로고
    • The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • DOI 10.1038/40194
    • Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389(6654):994-999. doi: 10.1038/40194 (Pubitemid 27485694)
    • (1997) Nature , vol.389 , Issue.6654 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5    Tissenbaum, H.A.6    Ruvkun, G.7
  • 24
    • 0031685525 scopus 로고    scopus 로고
    • Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans
    • Gems D, Sutton AJ, Sundermeyer ML, Albert PS, King KV, Edgley ML, Larsen PL, Riddle DL (1998) Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. Genetics 150(1):129-155 (Pubitemid 28415512)
    • (1998) Genetics , vol.150 , Issue.1 , pp. 129-155
    • Gems, D.1    Sutton, A.J.2    Sundermeyer, M.L.3    Albert, P.S.4    King, K.V.5    Edgley, M.L.6    Larsen, P.L.7    Riddle, D.L.8
  • 25
    • 41849128523 scopus 로고    scopus 로고
    • The FoxO code
    • DOI 10.1038/onc.2008.21, PII ONC200821
    • Calnan DR, Brunet A (2008) The FoxO code. Oncogene 27(16):2276-2288. doi: 10.1038/onc.2008.21 (Pubitemid 351501779)
    • (2008) Oncogene , vol.27 , Issue.16 , pp. 2276-2288
    • Calnan, D.R.1    Brunet, A.2
  • 26
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • 4366476 1:STN:280:DyaE2c3ntFWlsw%3D%3D
    • Brenner S (1974) The genetics of Caenorhabditis elegans. Genetics 77(1):71-94
    • (1974) Genetics , vol.77 , Issue.1 , pp. 71-94
    • Brenner, S.1
  • 27
    • 0014348411 scopus 로고
    • Selective enzyme purification by affinity chromatography
    • 4971842 10.1073/pnas.61.2.636 1:CAS:528:DyaF1MXisFynuw%3D%3D
    • Cuatrecasas P, Wilchek M, Anfinsen CB (1968) Selective enzyme purification by affinity chromatography. Proc Natl Acad Sci USA 61(2):636-643
    • (1968) Proc Natl Acad Sci USA , vol.61 , Issue.2 , pp. 636-643
    • Cuatrecasas, P.1    Wilchek, M.2    Anfinsen, C.B.3
  • 28
    • 0014806678 scopus 로고
    • Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads
    • 5432796 1:CAS:528:DyaE3cXktlaitL0%3D
    • Cuatrecasas P (1970) Protein purification by affinity chromatography. Derivatizations of agarose and polyacrylamide beads. J Biol Chem 245(12):3059-3065
    • (1970) J Biol Chem , vol.245 , Issue.12 , pp. 3059-3065
    • Cuatrecasas, P.1
  • 29
    • 0015591262 scopus 로고
    • Hydrophobic chromatography: Use for purification of glycogen synthetase
    • 4197628 10.1073/pnas.70.3.778 1:CAS:528:DyaE3sXkt1yktr8%3D
    • Shaltiel S, Er-El Z (1973) Hydrophobic chromatography: use for purification of glycogen synthetase. Proc Natl Acad Sci USA 70(3):778-781
    • (1973) Proc Natl Acad Sci USA , vol.70 , Issue.3 , pp. 778-781
    • Shaltiel, S.1    Er-El, Z.2
  • 30
    • 84886629814 scopus 로고
    • Purification and immunochemical characterization of the two adrenal cortex mitochondrial cytochrome P-450-proteins
    • DOI 10.1016/0003-9861(78)90278-3
    • Suhara K, Gomi T, Sato H, Itagaki E, Takemori S, Katagiri M (1978) Purification and immunochemical characterization of the two adrenal cortex mitochondrial cytochrome P-450-proteins. Arch Biochem Biophys 190(1):290-299. doi: 0003-9861(78)90278-3 (Pubitemid 9009714)
    • (1978) Archives of Biochemistry and Biophysics , vol.190 , Issue.1 , pp. 290-299
    • Suhara, K.1    Gomi, T.2    Sato, H.3
  • 31
    • 0018074896 scopus 로고
    • Purification and properties of cytochrome P-450 obtained from liver microsomes of untreated rats by lauric acid affinity chromatography
    • Gibson GG, Schenkman JB (1978) Purification and properties of cytochrome P-450 obtained from liver microsomes of untreated rats by lauric acid affinity chromatography. J Biol Chem 253(17):5957-5963 (Pubitemid 9014229)
    • (1978) Journal of Biological Chemistry , vol.253 , Issue.17 , pp. 5957-5963
    • Gibson, G.G.1    Schenkman, J.B.2
  • 32
    • 46049105780 scopus 로고    scopus 로고
    • Establishment of a PF2D-MS/MS platform for rapid profiling and semiquantitative analysis of membrane protein biomarkers
    • DOI 10.1002/pmic.200701022
    • Lee HJ, Kwon MS, Lee EY, Cho SY, Paik YK (2008) Establishment of a PF2D-MS/MS platform for rapid profiling and semiquantitative analysis of membrane protein biomarkers. Proteomics 8(11):2168-2177. doi: 10.1002/pmic.200701022 (Pubitemid 351898022)
    • (2008) Proteomics , vol.8 , Issue.11 , pp. 2168-2177
    • Lee, H.-J.1    Kwon, M.-S.2    Lee, E.-Y.3    Sang, Y.C.4    Paik, Y.-K.5
  • 33
    • 3242668095 scopus 로고    scopus 로고
    • Direct binding of cholesterol to the purified membrane region of SCAP: Mechanism for a sterol-sensing domain
    • DOI 10.1016/j.molcel.2004.06.019, PII S1097276504003521
    • Radhakrishnan A, Sun LP, Kwon HJ, Brown MS, Goldstein JL (2004) Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain. Mol Cell 15(2):259-268. doi: 10.1016/j.molcel.2004.06.019 (Pubitemid 38950972)
    • (2004) Molecular Cell , vol.15 , Issue.2 , pp. 259-268
    • Radhakrishnan, A.1    Sun, L.-P.2    Kwon, H.J.3    Brown, M.S.4    Goldstein, J.L.5
  • 34
    • 34547810054 scopus 로고    scopus 로고
    • Quantitative mass spectrometry identifies insulin signaling targets in C. elegans
    • DOI 10.1126/science.1139952
    • Dong MQ, Venable JD, Au N, Xu T, Park SK, Cociorva D, Johnson JR, Dillin A, Yates JR, 3rd (2007) Quantitative mass spectrometry identifies insulin signaling targets in C. elegans. Science 317 (5838):660-663. doi: 10.1126/science.1139952 (Pubitemid 47229964)
    • (2007) Science , vol.317 , Issue.5838 , pp. 660-663
    • Dong, M.-Q.1    Venable, J.D.2    Au, N.3    Xu, T.4    Sung, K.P.5    Cociorva, D.6    Johnson, J.R.7    Dillin, A.8    Yates III, J.R.9
  • 35
    • 70350365111 scopus 로고    scopus 로고
    • C. elegans major fats are stored in vesicles distinct from lysosome-related organelles
    • doi: 10.1016/j.cmet.2009.10.002
    • Rourke EJ, Soukas AA, Carr CE, Ruvkun G (2009) C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metabol 10(5):430-435. doi: 10.1016/j.cmet.2009.10.002
    • (2009) Cell Metabol , vol.10 , Issue.5 , pp. 430-435
    • Rourke, E.J.1    Soukas, A.A.2    Carr, C.E.3    Ruvkun, G.4
  • 38
    • 33750693058 scopus 로고    scopus 로고
    • Structure and function of nucleosome assembly proteins
    • DOI 10.1139/O06-088
    • Park YJ, Luger K (2006) Structure and function of nucleosome assembly proteins. Biochem Cell Biol 84(4):549-558. doi: 10.1139/o06-088 (Pubitemid 44703658)
    • (2006) Biochemistry and Cell Biology , vol.84 , Issue.4 , pp. 549-558
    • Park, Y.-J.1    Luger, K.2
  • 39
    • 33947719759 scopus 로고    scopus 로고
    • Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization
    • DOI 10.1016/j.yexcr.2007.01.018, PII S0014482707000481
    • Wyles JP, Perry RJ, Ridgway ND (2007) Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization. Exp Cell Res 313(7):1426-1437. doi: 10.1016/j.yexcr.2007.01.018 (Pubitemid 46507448)
    • (2007) Experimental Cell Research , vol.313 , Issue.7 , pp. 1426-1437
    • Wyles, J.P.1    Perry, R.J.2    Ridgway, N.D.3
  • 40
    • 50049116926 scopus 로고    scopus 로고
    • C. elegans dauer formation and the molecular basis of plasticity
    • 10.1101/gad.1701508 18708575 10.1101/gad.1701508 1:CAS:528: DC%2BD1cXhtVehtrzE
    • Fielenbach N, Antebi A (2008) C. elegans dauer formation and the molecular basis of plasticity. Genes Dev 22(16):2149-2165. doi: 10.1101/gad.1701508
    • (2008) Genes Dev , vol.22 , Issue.16 , pp. 2149-2165
    • Fielenbach, N.1    Antebi, A.2
  • 41
    • 0036175825 scopus 로고    scopus 로고
    • Stress resistance as a determinate of C. elegans lifespan
    • DOI 10.1016/S0047-6374(01)00422-5, PII S0047637401004225
    • Lithgow GJ, Walker GA (2002) Stress resistance as a determinate of C. elegans lifespan. Mech Ageing Dev 123 (7):765-771.pii:S0047637401004225 (Pubitemid 34178489)
    • (2002) Mechanisms of Ageing and Development , vol.123 , Issue.7 , pp. 765-771
    • Lithgow, G.J.1    Walker, G.A.2
  • 42
    • 0034967720 scopus 로고    scopus 로고
    • Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
    • DOI 10.1038/88850
    • Lin K, Hsin H, Libina N, Kenyon C (2001) Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. Nat Genet 28(2):139-145. doi: 10.1038/88850 (Pubitemid 32538058)
    • (2001) Nature Genetics , vol.28 , Issue.2 , pp. 139-145
    • Lin, K.1    Hsin, H.2    Libina, N.3    Kenyon, C.4
  • 43
    • 40849118472 scopus 로고    scopus 로고
    • Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans
    • DOI 10.1016/j.cell.2008.01.030, PII S009286740800130X
    • Tullet JM, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK (2008) Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132 (6):1025-1038. doi: 10.1016/j.cell.2008.01.030 (Pubitemid 351391953)
    • (2008) Cell , vol.132 , Issue.6 , pp. 1025-1038
    • Tullet, J.M.A.1    Hertweck, M.2    An, J.H.3    Baker, J.4    Hwang, J.Y.5    Liu, S.6    Oliveira, R.P.7    Baumeister, R.8    Blackwell, T.K.9
  • 45
    • 33644966988 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation
    • 10.1242/jcs.02758 16443755 10.1242/jcs.02758 1:CAS:528: DC%2BD28Xit1Klt78%3D
    • Phillips JE, Gersbach CA, Wojtowicz AM, Garcia AJ (2006) Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. J Cell Sci 119(Pt 3):581-591. doi: 10.1242/jcs.02758
    • (2006) J Cell Sci , vol.119 , Issue.PART 3 , pp. 581-591
    • Phillips, J.E.1    Gersbach, C.A.2    Wojtowicz, A.M.3    Garcia, A.J.4
  • 46
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • DOI 10.1016/S0092-8674(00)80213-5
    • Brown MS, Goldstein JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89(3):331-340 (Pubitemid 27220877)
    • (1997) Cell , vol.89 , Issue.3 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 48
    • 1642524289 scopus 로고    scopus 로고
    • Proteomic changes during disturbance of cholesterol metabolism by azacoprostane treatment in Caenorhabditis elegans
    • 10.1074/mcp.M300036-MCP200M300036-MCP200 12904448 10.1074/mcp.M300036- MCP200 1:CAS:528:DC%2BD3sXovFWmt7o%3D
    • Choi BK, Chitwood DJ, Paik YK (2003) Proteomic changes during disturbance of cholesterol metabolism by azacoprostane treatment in Caenorhabditis elegans. Mol Cell Proteomics 2(10):1086-1095. doi: 10.1074/mcp.M300036-MCP200M300036- MCP200
    • (2003) Mol Cell Proteomics , vol.2 , Issue.10 , pp. 1086-1095
    • Choi, B.K.1    Chitwood, D.J.2    Paik, Y.K.3
  • 49
    • 15944380730 scopus 로고    scopus 로고
    • Long-term effects of sterol depletion in C. elegans: Sterol content of synchronized wild-type and mutant populations
    • DOI 10.1194/jlr.M400100-JLR200
    • Merris M, Kraeft J, Tint GS, Lenard J (2004) Long-term effects of sterol depletion in C. elegans: sterol content of synchronized wild-type and mutant populations. J Lipid Res 45(11):2044-2051. doi: 10.1194/jlr.M400100- JLR200M400100-JLR200 (Pubitemid 40990899)
    • (2004) Journal of Lipid Research , vol.45 , Issue.11 , pp. 2044-2051
    • Merris, M.1    Kraeft, J.2    Tint, G.S.3    Lenard, J.4
  • 50
    • 13744249412 scopus 로고    scopus 로고
    • Cholesterol-producing transgenic Caenorhabditis elegans lives longer due to newly acquired enhanced stress resistance
    • DOI 10.1016/j.bbrc.2005.01.050
    • Lee EY, Shim YH, Chitwood DJ, Hwang SB, Lee J, Paik YK (2005) Cholesterol-producing transgenic Caenorhabditis elegans lives longer due to newly acquired enhanced stress resistance. Biochem Biophys Res Commun 328(4):929-936. doi: 10.1016/j.bbrc.2005.01.050 (Pubitemid 40238726)
    • (2005) Biochemical and Biophysical Research Communications , vol.328 , Issue.4 , pp. 929-936
    • Lee, E.-Y.1    Shim, Y.-H.2    Chitwood, D.J.3    Hwang, S.B.4    Lee, J.5    Paik, Y.-K.6
  • 51
    • 10344229417 scopus 로고    scopus 로고
    • NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways
    • DOI 10.1242/dev.01408
    • Li J, Brown G, Ailion M, Lee S, Thomas JH (2004) NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways. Development 131(22):5741-5752. doi: 10.1242/dev.01408 (Pubitemid 39625216)
    • (2004) Development , vol.131 , Issue.22 , pp. 5741-5752
    • Li, J.1    Brown, G.2    Ailion, M.3    Lee, S.4    Thomas, J.H.5
  • 53
    • 0037295514 scopus 로고    scopus 로고
    • Knockout targeting of the Drosophila Nap1 gene and examination of DNA repair tracts in the recombination products
    • Lankenau S, Barnickel T, Marhold J, Lyko F, Mechler BM, Lankenau DH (2003) Knockout targeting of the Drosophila nap1 gene and examination of DNA repair tracts in the recombination products. Genetics 163(2):611-623 (Pubitemid 36314544)
    • (2003) Genetics , vol.163 , Issue.2 , pp. 611-623
    • Lankenau, S.1    Barnickel, T.2    Marhold, J.3    Lyko, F.4    Mechler, B.M.5    Lankenau, D.-H.6
  • 54
    • 0034425702 scopus 로고    scopus 로고
    • Control of neurulation by the nucleosome assembly protein-1-like 2
    • DOI 10.1038/78124
    • Rogner UC, Spyropoulos DD, Le Novere N, Changeux JP, Avner P (2000) Control of neurulation by the nucleosome assembly protein-1-like 2. Nat Genet 25(4):431-435. doi: 10.1038/78124 (Pubitemid 32983437)
    • (2000) Nature Genetics , vol.25 , Issue.4 , pp. 431-435
    • Rogner, U.C.1    Spyropoulos, D.D.2    Le Novere, N.3    Changeux, J.-P.4    Avner, P.5
  • 55
    • 38149069055 scopus 로고    scopus 로고
    • Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein
    • 10.1074/jbc.M707943200 17989073 10.1074/jbc.M707943200 1:CAS:528:DC%2BD1cXhsFakug%3D%3D
    • Infante RE, Abi-Mosleh L, Radhakrishnan A, Dale JD, Brown MS, Goldstein JL (2008) Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein. J Biol Chem 283(2):1052-1063. doi: 10.1074/jbc.M707943200
    • (2008) J Biol Chem , vol.283 , Issue.2 , pp. 1052-1063
    • Infante, R.E.1    Abi-Mosleh, L.2    Radhakrishnan, A.3    Dale, J.D.4    Brown, M.S.5    Goldstein, J.L.6
  • 57
    • 0344838432 scopus 로고    scopus 로고
    • The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels
    • DOI 10.1073/pnas.0530027100
    • Ko DC, Binkley J, Sidow A, Scott MP (2003) The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. Proc Natl Acad Sci USA 100(5):2518-2525. doi: 10.1073/pnas.05300271000530027100 (Pubitemid 36297531)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.5 , pp. 2518-2525
    • Ko, D.C.1    Binkley, J.2    Sidow, A.3    Scott, M.P.4
  • 58
    • 34248162451 scopus 로고    scopus 로고
    • The nucleosome assembly activity of NAP1 is enhanced by alien
    • DOI 10.1128/MCB.01106-06
    • Eckey M, Hong W, Papaioannou M, Baniahmad A (2007) The nucleosome assembly activity of NAP1 is enhanced by Alien. Mol Cell Biol 27(10):3557-3568. doi: 10.1128/MCB.01106-06 (Pubitemid 46726167)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.10 , pp. 3557-3568
    • Eckey, M.1    Hong, W.2    Papaioannou, M.3    Baniahmad, A.4
  • 60
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • DOI 10.1016/S0960-9822(01)00594-2
    • Henderson ST, Johnson TE (2001) daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 11 (24):1975-1980. pii: S0960-9822(01)00594-2 (Pubitemid 33146425)
    • (2001) Current Biology , vol.11 , Issue.24 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 61
    • 46749094102 scopus 로고    scopus 로고
    • Hepatic insulin resistance directly promotes formation of cholesterol gallstones
    • 10.1038/nm1785 18587407 10.1038/nm1785 1:CAS:528:DC%2BD1cXotF2lurk%3D
    • Biddinger SB, Haas JT, Yu BB, Bezy O, Jing E, Zhang W, Unterman TG, Carey MC, Kahn CR (2008) Hepatic insulin resistance directly promotes formation of cholesterol gallstones. Nat Med 14(7):778-782. doi: 10.1038/nm1785
    • (2008) Nat Med , vol.14 , Issue.7 , pp. 778-782
    • Biddinger, S.B.1    Haas, J.T.2    Yu, B.B.3    Bezy, O.4    Jing, E.5    Zhang, W.6    Unterman, T.G.7    Carey, M.C.8    Kahn, C.R.9
  • 62
    • 33748312093 scopus 로고    scopus 로고
    • Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
    • DOI 10.1172/JCI27047
    • Matsumoto M, Han S, Kitamura T, Accili D (2006) Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. J Clin Invest 116(9):2464-2472. doi: 10.1172/JCI27047 (Pubitemid 44330145)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.9 , pp. 2464-2472
    • Matsumoto, M.1    Han, S.2    Kitamura, T.3    Accili, D.4
  • 63
    • 26944461217 scopus 로고    scopus 로고
    • Transcriptional feedback control of insulin receptor by dFOXO/FOXO1
    • DOI 10.1101/gad.1340505
    • Puig O, Tjian R (2005) Transcriptional feedback control of insulin receptor by dFOXO/FOXO1. Genes Dev 19(20):2435-2446. doi: 10.1101/gad.1340505 (Pubitemid 41483691)
    • (2005) Genes and Development , vol.19 , Issue.20 , pp. 2435-2446
    • Puig, O.1    Tjian, R.2
  • 64
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-Specific Activities of C. elegans DAF-16 in the Regulation of Lifespan
    • DOI 10.1016/S0092-8674(03)00889-4
    • Libina N, Berman JR, Kenyon C (2003) Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115 (4):489-502. pii:S0092867403008894 (Pubitemid 37456810)
    • (2003) Cell , vol.115 , Issue.4 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 65
    • 13244287966 scopus 로고    scopus 로고
    • Regulation of FoxO activity by CBP/p300-mediated acetylation
    • DOI 10.1016/j.tibs.2004.12.002, PII S0968000404003019
    • van der Heide LP, Smidt MP (2005) Regulation of FoxO activity by CBP/p300-mediated acetylation. Trends Biochem Sci 30(2):81-86. doi: 10.1016/j.tibs.2004.12.002 (Pubitemid 40187300)
    • (2005) Trends in Biochemical Sciences , vol.30 , Issue.2 , pp. 81-86
    • Van Der Heide, L.P.1    Smidt, M.P.2
  • 66
    • 0036236469 scopus 로고    scopus 로고
    • Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro
    • DOI 10.1128/MCB.22.9.2974-2983.2002
    • Asahara H, Tartare-Deckert S, Nakagawa T, Ikehara T, Hirose F, Hunter T, Ito T, Montminy M (2002) Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Mol Cell Biol 22(9):2974-2983 (Pubitemid 34437456)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.9 , pp. 2974-2983
    • Asahara, H.1    Tartare-Deckert, S.2    Nakagawa, T.3    Ikehara, T.4    Hirose, F.5    Hunter, T.6    Ito, T.7    Montminy, M.8
  • 67
    • 60749131994 scopus 로고    scopus 로고
    • Dyslipidemia in type 2 diabetes mellitus
    • 10.1038/ncpendmet1066 19229235 10.1038/ncpendmet1066 1:CAS:528: DC%2BD1MXit1KrtLc%3D
    • Mooradian AD (2009) Dyslipidemia in type 2 diabetes mellitus. Nat Clin Pract Endocrinol Metab 5(3):150-159. doi: 10.1038/ncpendmet1066
    • (2009) Nat Clin Pract Endocrinol Metab , vol.5 , Issue.3 , pp. 150-159
    • Mooradian, A.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.