Cholesterol-producing transgenic Caenorhabditis elegans lives longer due to newly acquired enhanced stress resistance

Biochemical and Biophysical Research Communications

Volumn 328, Issue 4, 2005, Pages 929-936

  Lee, Eun Young ^a   Shim, Yhong Hee ^b   Chitwood, David J ^c   Hwang, Soon Baek ^d   Lee, Junho ^d   Paik, Young Ki ^a  

^a Yonsei University   (South Korea)

^b Konkuk University   (South Korea)

^c AGRICULTURAL RESEARCH SERVICE   (United States)

^d Seoul National University   (South Korea)

Author keywords

7 Dehydrocholesterol reductase; Aging; Cholegans; Life span; Longevity; Oxidative stress

Indexed keywords

7 DEHYDROCHOLESTEROL; CHOLESTEROL; OXIDOREDUCTASE; STEROL;

ARTICLE; BIOCHEMISTRY; CAENORHABDITIS ELEGANS; CHEMICAL COMPOSITION; CHROMOSOME; COMPARATIVE STUDY; CONTROLLED STUDY; GAMMA IRRADIATION; GROWTH RATE; HEAT TOLERANCE; LIFESPAN; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; THERMAL ANALYSIS; TRANSGENIC ORGANISM; ULTRAVIOLET RADIATION; WILD TYPE;

CAENORHABDITIS ELEGANS;

EID: 13744249412     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.01.050     Document Type: Article

References (25)

1. P.M. Lewis, M.P. Dunn, J.A. McMahon, M. Logan, J.F. Martin, B. St-Jacques, and A.P. McMahon Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1 Cell 105 2001 599 612
2. D.J. Chitwood, W.R. Lusby, R. Lozano, M.J. Thompson, and J.A. Svoboda Novel nuclear methylation of sterols by the nematode Caenorhabditis elegans Steroids 42 1983 311 319
3. T.V. Kurzchalia, and S. Ward Why do worms need cholesterol? Nat. Cell Biol. 8 2003 684 688
4. B.K. Choi, D.J. Chitwood, and Y.K. Paik Proteomic changes during disturbance of cholesterol metabolism by azacoprostane treatment in Caenorhabditis elegans Mol. Cell Proteomics 2 2003 1086 1095
5. W. Gaoua, F. Chevy, C. Roux, and C. Wolf Oxidized derivatives of 7-dehydrocholesterol induce growth retardation in cultured rat embryos: a model for antenatal growth retardation in the Smith-Lemli-Opitz syndrome J. Lipid Res. 40 1999 456 463
6. Y. Honda, and S. Honda Oxidative stress and life span determination in the nematode Caenorhabditis elegans Ann. N.Y. Acad. Sci. 959 2002 466 474
7. S. Melov, J. Ravenscroft, S. Malik, M.S. Gill, D.W. Walker, P.E. Clayton, D.C. Wallace, B. Malfroy, S.R. Doctrow, and G.J. Lithgow Extension of life-span with superoxide dismutase/catalase mimetics Science 289 2000 1567 1569
8. S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71 94
9. Y.H. Shim, J.H. Chun, E.Y. Lee, and Y.K. Paik Role of cholesterol in germ-line development of Caenorhabditis elegans Mol. Reprod. Dev. 61 2002 358 366
10. C.C. Mello, J.M. Kramer, D. Stinchcomb, and V. Ambros Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences EMBO. J. 12 1991 3959 3970
11. B.U. Fitzky, M. Witsch-Baumgartner, M. Erdel, J.N. Lee, Y.K. Paik, H. Glossmann, G. Utermann, and F.F. Moebius Mutations in the delta 7-sterol reductase gene in patients with the Smith-Lemli-Opitz syndrome Proc. Natl. Acad. Sci. USA 95 1998 8181 8186
12. C.I. Bargmann, E. Hartwieg, and H.R. Horvitz Odorant-selective genes and neurons mediate olfaction in C. elegans Cell 74 1993 515 527
13. H. Adachi, Y. Fujiwara, and N. Ishii Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans J. Gerontol. 53 1998 240 244
14. D. Gems, A.J. Sutton, M.L. Sundermeyer, P.S. Albert, K.V. King, M.L. Edgley, P.L. Larsen, and D.L. Riddle Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans Genetics 150 1998 129 155
15. D.J. Chitwood Biochemistry and function of nematode steroids Crit. Rev. Biochem. Mol. Biol. 34 1999 273 284
16. S. Murakami, and T.E. Johnson A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans Genetics 143 1996 1207 1218
17. G.J. Lithgow, T.M. White, S. Melov, and T.E. Johnson Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress Proc. Natl. Acad. Sci. USA 92 1995 7540 7544
18. V.D. Longo, E.B. Gralla, and J.S. Valentine Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo J. Biol. Chem. 271 1996 12275 12280
19. J.N. Lee, and Y.K. Paik Cholesterol biosynthesis from lanosterol: development of a novel assay method, characterization, and solubilization of rat hepatic microsomal sterol delta7-reductase J. Biochem. Mol. Biol. 30 1997 370 377
20. Y.K. Paik, J.M. Trzaskos, A. Shafiee, and J.L. Gaylor Microsomal enzymes of cholesterol biosynthesis from lanosterol. Characterization, solubilization, and partial purification of NADPH-dependent delta 8,14-steroid 14-reductase J. Biol. Chem. 259 1984 13413 13423
21. S.H. Bae, and Y.K. Paik Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol delta 24-reductase Biochem. J. 326 1997 609 616
22. R.A. Bowman, G.L. O'Neill, and T.V. Riley Non-radioactive restriction fragment length polymorphism (RFLP) typing of Clostridium difficile FEMS Microbiol. Lett. 63 1991 269 272
23. G.A. Walker, D.W. Walker, and G.J. Lithgow A relationship between thermotolerance and longevity in Caenorhabditis elegans J. Invest. Dermatol. Symp. Proc. 1 1998 6 10
24. J.A. Joseph, R. Villalobos-Molinas, N.A. Denisova, S. Erat, and J. Strain Cholesterol: A two-edged sword in brain aging Free. Radic. Biol. Med. 22 1997 455 462
25. S.H. Bae, J.N. Lee, B.U. Fitzky, J. Seong, and Y.K. Paik Cholesterol biosynthesis from lanosterol. Molecular cloning, tissue distribution, expression, chromosomal localization, and regulation of rat 7-dehydrocholesterol reductase, a Smith-Lemli-Opitz syndrome-related protein J. Biol. Chem. 274 1999 14624 14631