Flaxseed oil does not affect inflammatory markers and lipid profile compared to olive oil, in young, healthy, normal weight adults

Metabolism: Clinical and Experimental

Volumn 62, Issue 5, 2013, Pages 686-693

  Kontogianni, Meropi D ^a   Vlassopoulos, Antonis ^a   Gatzieva, Alexandra ^a   Farmaki, Aliki Eleni ^a   Katsiougiannis, Stergios ^a   Panagiotakos, Demosthenes B ^a   Kalogeropoulos, Nick ^a   Skopouli, Fotini N ^a  

^a HAROKOPIO UNIVERSITY   (Greece)

Author keywords

Linolenic acid; Adiponectin; Cholesterol; TNF

Indexed keywords

ADIPONECTIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LINSEED OIL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OLIVE OIL; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BODY HEIGHT; BODY MASS; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIETARY INTAKE; ENZYME CHEMISTRY; ERYTHROCYTE; FATTY ACID ANALYSIS; FEMALE; GLUCOSE BLOOD LEVEL; HIP CIRCUMFERENCE; HUMAN; MALE; NORMAL HUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; REDUCTION; TRIACYLGLYCEROL BLOOD LEVEL;

ADOLESCENT; ADULT; AGE FACTORS; BIOLOGICAL MARKERS; CROSS-OVER STUDIES; FEMALE; HEALTH; HUMANS; IDEAL BODY WEIGHT; INFLAMMATION MEDIATORS; LINSEED OIL; LIPID METABOLISM; MALE; METABOLOME; PLANT OILS; YOUNG ADULT;

EID: 84876681696     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.11.007     Document Type: Article

References (47)

1. R. da Silva, A. Bach-Faig, B. Raido Quintana, G. Buckland, M.D. Vaz de Almeida, and L. Serra-Majem Worldwide variation of adherence to the Mediterranean diet, in 1961-1965 and 2000-2003 Public Health Nutr 12 2009 1676 1684
2. P. Yaqoob, J.A. Knapper, D.H. Webb, C.M. Williams, E.A. Newsholme, and P.C. Calder Effect of olive oil on immune function in middle-aged men Am J Clin Nutr 67 1998 129 135 (Pubitemid 28037637)
3. E. Martinez-Dominguez, R. de la Puerta, and V. Ruiz-Gutierrez Protective effects upon experimental inflammation models of a polyphenol-supplemented virgin olive oil diet Inflamm Res 50 2001 102 106 (Pubitemid 32210151)
4. M. Bullo, P. Casas-Agustench, P. Amigo-Correig, J. Aranceta, and J. Salas-Salvado Inflammation, obesity and comorbidities: The role of diet Public Health Nutr 10 2007 1164 1172 (Pubitemid 350085205)
5. R. de La Puerta Vazquez, E. Martinez-Dominguez, J. Sanchez Perona, and V. Ruiz-Gutierrez Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils Metabolism 53 2004 59 65 (Pubitemid 38071937)
6. Y.M. Pacheco, B. Bemudez, S. Lopez, R. Abia, J. Villar, and F.J. Muriana Minor compounds of olive oil have postprandial anti-inflammatory effects Br J Nutr 98 2007 260 263 (Pubitemid 47091366)
7. P. Bogani, C. Galli, M. Villa, and F. Visioli Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil Atherosclerosis 190 2007 181 186 (Pubitemid 44908313)
8. R. Estruch, M.A. Martinez-Gonzalez, D. Corella, J. Salas-Salvado, V. Ruiz-Gutierrez, and M.I. Covas Effects of a Mediterranean-style diet on cardiovascular risk factors: A randomized trial Ann Intern Med 145 2006 1 11 (Pubitemid 46780599)
9. K. Esposito, R. Marfella, M. Ciotola, C. Di Palo, F. Giugliano, and G. Giugliano Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: A randomized trial JAMA 292 2004 1440 1446 (Pubitemid 39258336)
10. F.B. Hu, and W.C. Willett Optimal diets for prevention of coronary heart disease JAMA 288 2002 2569 2578 (Pubitemid 35386892)
11. A.P. Simopoulos The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases Exp Biol Med (Maywood) 233 2008 674 688
12. T. Pischon, S.E. Hankinson, G.S. Hotamisligil, N. Rifai, W.C. Willett, and E.B. Rimm Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women Circulation 108 2003 155 160 (Pubitemid 36871296)
13. P.M. Kris-Etherton, W.S. Harris, and L.J. Appel Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease Circulation 106 2002 2747 2757 (Pubitemid 35364932)
14. K.K. Singh, D. Mridula, J. Rehal, and P. Barnwal Flaxseed: A potential source of food, feed and fiber Crit Rev Food Sci Nutr 51 2011 210 222
15. A. Pan, D. Yu, W. Demark-Wahnefried, O.H. Franco, and X. Lin Meta-analysis of the effects of flaxseed interventions on blood lipids Am J Clin Nutr 90 2009 288 297
16. E. Lopez-Garcia, M.B. Schulze, J.E. Manson, J.B. Meigs, C.M. Albert, and N. Rifai Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women J Nutr 134 2004 1806 1811 (Pubitemid 38886573)
17. L.S. Rallidis, G. Paschos, G.K. Liakos, A.H. Velissaridou, G. Anastasiadis, and A. Zampelas Dietary alpha-linolenic acid decreases C-reactive protein, serum amyloid A and interleukin-6 in dyslipidaemic patients Atherosclerosis 167 2003 237 242 (Pubitemid 36773523)
18. T.L. Nelson, J.R. Stevens, and M.S. Hickey Inflammatory markers are not altered by an eight week dietary alpha-linolenic acid intervention in healthy abdominally obese adult males and females Cytokine 38 2007 101 106 (Pubitemid 47077908)
19. F.M. Silva, J.C. de Almeida, and A.M. Feoli Effect of diet on adiponectin levels in blood Nutr Rev 69 2011 599 612
20. G.K. Paschos, A. Zampelas, D.B. Panagiotakos, S. Katsiougiannis, B.A. Griffin, and V. Votteas Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men Eur J Nutr 46 2007 315 320 (Pubitemid 47353605)
21. T.L. Nelson, J.R. Stevens, and M.S. Hickey Adiponectin levels are reduced, independent of polymorphisms in the adiponectin gene, after supplementation with alpha-linolenic acid among healthy adults Metabolism 56 2007 1209 1215 (Pubitemid 47223260)
22. M.L. Vargas, R.U. Almario, W. Buchan, K. Kim, and S.E. Karakas Metabolic and endocrine effects of long-chain versus essential omega-3 polyunsaturated fatty acids in polycystic ovary syndrome Metabolism 60 2011 1711 1718
23. O. Molendi-Coste, V. Legry, and I.A. Leclercq Why and how meet n-3 PUFA dietary recommendations? Gastroenterol Res Pract. 2011 2011 364040
24. A.L. Choi, S. Cordier, P. Weihe, and P. Grandjean Negative confounding in the evaluation of toxicity: The case of methylmercury in fish and seafood Crit Rev Toxicol 38 2008 877 893
25. P.L. Goyens, M.E. Spilker, P.L. Zock, M.B. Katan, and R.P. Mensink Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio Am J Clin Nutr 84 2006 44 53 (Pubitemid 44699170)
26. World Medical Association declaration of Helsinki Recommendations guiding physicians in biomedical research involving human subjects JAMA 277 1997 925 926
27. D.B. Panagiotakos, C. Pitsavos, and C. Stefanadis Dietary patterns: A Mediterranean diet score and its relation to clinical and biological markers of cardiovascular disease risk Nutr Metab Cardiovasc Dis 16 2006 559 568 (Pubitemid 44780080)
28. University of Crete, Department of Medicine, and Technological Institute of Thessaloniki, Nutrition Department Greek food composition tables [cited 2012 February15 ]; Available from: http://nutrition.med.uoc.gr/GreekTables 2001
29. A. Trichopoulou, and K. Georga Composition tables of simple and composite foods 2004 Parisianos Scientific Publications Athens
30. M. Kollia, S. Kavouras, A. Gioxari, M. Maraki, and L. Sidossis Development, validity and reliability of the Harokopio Physical Activity Questionnaire in Greek adults 8th Panhellenic Congress on Nutrition and Dietetics; 2006; Athens 2006 130 131
31. W.T. Friedewald, and R.I.F.D. Levy Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentifuge Clin Chem 18 1972 499 502
32. H.G. Rose, and M. Oklander Improved procedure for the extraction of lipids from human erythrocytes J Lipid Res 6 1965 428 431
33. G. Lepage, and C.C. Roy Direct transesterification of all classes of lipids in a one-step reaction J Lipid Res 27 1986 114 120 (Pubitemid 16045295)
34. Y.E. Finnegan, A.M. Minihane, E.C. Leigh-Firbank, S. Kew, G.W. Meijer, and R. Muggli Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects Am J Clin Nutr 77 2003 783 795
35. N. Kaul, R. Kreml, J.A. Austria, M.N. Richard, A.L. Edel, and E. Dibrov A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers J Am Coll Nutr 27 2008 51 58 (Pubitemid 351600522)
36. F. Guebre-Egziabher, R. Rabasa-Lhoret, F. Bonnet, J.P. Bastard, M. Desage, and M.R. Skilton Nutritional intervention to reduce the n-6/n-3 fatty acid ratio increases adiponectin concentration and fatty acid oxidation in healthy subjects Eur J Clin Nutr 62 2008 1287 1293
37. L.G. Gillingham, J.A. Gustafson, S.Y. Han, D.S. Jassal, and P.J. Jones High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects Br J Nutr 105 2011 417 427
38. G.E. Caughey, E. Mantzioris, R.A. Gibson, L.G. Cleland, and M.J. James The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil Am J Clin Nutr 63 1996 116 122 (Pubitemid 26005735)
39. G. Barcelo-Coblijn, E.J. Murphy, R. Othman, M.H. Moghadasian, T. Kashour, and J.K. Friel Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: A multiple-dosing trial comparing 2 sources of n-3 fatty acid Am J Clin Nutr 88 2008 801 809
40. G. Zhao, T.D. Etherton, K.R. Martin, S.G. West, P.J. Gillies, and P.M. Kris-Etherton Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women J Nutr 134 2004 2991 2997 (Pubitemid 39470074)
41. G.K. Paschos, L.S. Rallidis, G.K. Liakos, D. Panagiotakos, G. Anastasiadis, and V. Votteas Background diet influences the anti-inflammatory effect of alpha-linolenic acid in dyslipidaemic subjects Br J Nutr 92 2004 649 655 (Pubitemid 39406647)
42. F.L. Crowe, N.E. Allen, P.N. Appleby, K. Overvad, I.V. Aardestrup, and N.F. Johnsen Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition Am J Clin Nutr 88 2008 1353 1363
43. P.C. Calder, R. Albers, J.M. Antoine, S. Blum, R. Bourdet-Sicard, and G.A. Ferns Inflammatory disease processes and interactions with nutrition Br J Nutr 101 Suppl 1 2009 S1 S45
44. Y. Min, C. Lowy, S. Islam, F.S. Khan, and R. Swaminathan Relationship between red cell membrane fatty acids and adipokines in individuals with varying insulin sensitivity Eur J Clin Nutr 65 2011 690 695
45. M. Itoh, T. Suganami, N. Satoh, K. Tanimoto-Koyama, X. Yuan, and M. Tanaka Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects Arterioscler Thromb Vasc Biol 27 2007 1918 1925 (Pubitemid 47315642)
46. S. Neschen, K. Morino, J.C. Rossbacher, R.L. Pongratz, G.W. Cline, and S. Sono Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice Diabetes 55 2006 924 928 (Pubitemid 44100165)
47. A. Banga, R. Unal, P. Tripathi, I. Pokrovskaya, R.J. Owens, and P.A. Kern Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids Am J Physiol Endocrinol Metab 2009 E480 E489