Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 329, Issue 1, 2009, Pages 112-122

  Oh, Seon Hee ^a   Lim, Sung Chul ^a  

^a Chosun University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 3 METHYLADENINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CAPSAICIN; CASPASE 4; DIHYDROCAPSAICIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; MICROTUBULE ASSOCIATED PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN IRE1; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; THAPSIGARGIN; WORTMANNIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; UPREGULATION;

APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CAPSAICIN; CELL LINE; CELL SURVIVAL; CYTOPLASM; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MICROSCOPY, ELECTRON, TRANSMISSION; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN FOLDING; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION; VACUOLES;

EID: 63849308518     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.144113     Document Type: Article

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