-
1
-
-
33744490096
-
Aging is no longer an unsolved problem in biology
-
Holliday R. Aging is no longer an unsolved problem in biology. Ann NY Acad Sci 2006;1067:1-9.
-
(2006)
Ann NY Acad Sci
, vol.1067
, pp. 1-9
-
-
Holliday, R.1
-
2
-
-
66049160126
-
The ageing epigenome: Damaged beyond repair?
-
Sinclair D, Oberdoerffer P. The ageing epigenome: Damaged beyond repair? Ageing Res Rev 2009;8:189-198.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 189-198
-
-
Sinclair, D.1
Oberdoerffer, P.2
-
3
-
-
84859491432
-
Re-programmed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
-
Ohmine S, Squillace KA, Hartjes KA, Deeds MC, Armstrong AS, Thatava T, Sakuma T, Terzic A, Kudva Y, Ikeda Y. Re-programmed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging (Albany NY) 2012;4:60-73.
-
(2012)
Aging (Albany NY)
, vol.4
, pp. 60-73
-
-
Ohmine, S.1
Squillace, K.A.2
Hartjes, K.A.3
Deeds, M.C.4
Armstrong, A.S.5
Thatava, T.6
Sakuma, T.7
Terzic, A.8
Kudva, Y.9
Ikeda, Y.10
-
4
-
-
79960375714
-
Epigenetic regulation of aging stem cells
-
Pollina EA, Brunet A. Epigenetic regulation of aging stem cells. Oncogene 2011;30:3105-3126.
-
(2011)
Oncogene
, vol.30
, pp. 3105-3126
-
-
Pollina, E.A.1
Brunet, A.2
-
5
-
-
84868012309
-
Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration
-
Paliwal P, Pishesha N, Wijaya D, Conboy IM. Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration. Aging (Albany NY) 2012;4:553-566.
-
(2012)
Aging (Albany NY)
, vol.4
, pp. 553-566
-
-
Paliwal, P.1
Pishesha, N.2
Wijaya, D.3
Conboy, I.M.4
-
6
-
-
77951664071
-
Molecular aging and rejuvenation of human muscle stem cells
-
Carlson ME, Suetta C, Conboy MJ, Aagaard P, Mackey A, Kjaer M, Conboy I. Molecular aging and rejuvenation of human muscle stem cells. EMBO Mol Med 2009;1:381-391.
-
(2009)
EMBO Mol Med
, vol.1
, pp. 381-391
-
-
Carlson, M.E.1
Suetta, C.2
Conboy, M.J.3
Aagaard, P.4
MacKey, A.5
Kjaer, M.6
Conboy, I.7
-
7
-
-
47949097215
-
Imbalance between PSMAD3 and notch induces CDK inhibitors in old muscle stem cells
-
Carlson ME, Hsu M, Conboy IM. Imbalance between PSMAD3 and notch induces CDK inhibitors in old muscle stem cells. Nature 2008;454:528-532.
-
(2008)
Nature
, vol.454
, pp. 528-532
-
-
Carlson, M.E.1
Hsu, M.2
Conboy, I.M.3
-
8
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005;433: 760-764.
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weissman, I.L.5
Rando, T.A.6
-
10
-
-
84867659145
-
The influence of reactive oxygen species on cell cycle progression in mammalian cells
-
Verbon EH, Post JA, Boonstra J. The influence of reactive oxygen species on cell cycle progression in mammalian cells. Gene 2012;511:1-6.
-
(2012)
Gene
, vol.511
, pp. 1-6
-
-
Verbon, E.H.1
Post, J.A.2
Boonstra, J.3
-
12
-
-
84856951081
-
Reactive oxygen species: Are they important for haematopoiesis?
-
Sardina JL, López-Ruano G, Sánchez-Sánchez B, Llanillo M, Hernández-Hernández A. Reactive oxygen species: Are they important for haematopoiesis? Crit Rev Oncol Hematol 2012;81:257-274.
-
(2012)
Crit Rev Oncol Hematol
, vol.81
, pp. 257-274
-
-
Sardina, J.L.1
López-Ruano, G.2
Sánchez-Sánchez, B.3
Llanillo, M.4
Hernández-Hernández, A.5
-
13
-
-
84866382187
-
ROS homeostasis during development: An evolutionary conserved strategy
-
Schippers JHM, Nguyen HM, Lu D, Schmidt R, Mueller-Roeber B. ROS homeostasis during development: An evolutionary conserved strategy. Cell Mol Life Sci 2012;69: 3245-3257.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 3245-3257
-
-
Schippers, J.H.M.1
Nguyen, H.M.2
Lu, D.3
Schmidt, R.4
Mueller-Roeber, B.5
-
14
-
-
77952543118
-
Mitochondrial redox metabolism: Aging, longevity and dietary effects
-
Page MM, Robb EL, Salway KD, Stuart JA. Mitochondrial redox metabolism: Aging, longevity and dietary effects. Mech Ageing Dev 2010;131:242-252.
-
(2010)
Mech Ageing Dev
, vol.131
, pp. 242-252
-
-
Page, M.M.1
Robb, E.L.2
Salway, K.D.3
Stuart, J.A.4
-
15
-
-
84855217118
-
Mitochondria sentencing about cellular life and death: A matter of oxida-tive stress
-
Apostolova N, Blas-Garcia A, Esplugues JV. Mitochondria sentencing about cellular life and death: A matter of oxida-tive stress. Curr Pharm Des 2011;17:4047-4060.
-
(2011)
Curr Pharm des
, vol.17
, pp. 4047-4060
-
-
Apostolova, N.1
Blas-Garcia, A.2
Esplugues, J.V.3
-
16
-
-
77952291931
-
Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells
-
Yoneyama M, Kawada K, Gotoh Y, Shiba T, Ogita K. Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells. Neurochem Int 2010; 56:740-746.
-
(2010)
Neurochem Int
, vol.56
, pp. 740-746
-
-
Yoneyama, M.1
Kawada, K.2
Gotoh, Y.3
Shiba, T.4
Ogita, K.5
-
17
-
-
84873410016
-
Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration
-
Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E. Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Nat Cell Biol 2012;15:222-228.
-
(2012)
Nat Cell Biol
, vol.15
, pp. 222-228
-
-
Love, N.R.1
Chen, Y.2
Ishibashi, S.3
Kritsiligkou, P.4
Lea, R.5
Koh, Y.6
Gallop, J.L.7
Dorey, K.8
Amaya, E.9
-
18
-
-
79959521749
-
The redox basis of epigenetic modifications: From mechanisms to functional consequences
-
Cyr AR, Domann FE. The redox basis of epigenetic modifications: From mechanisms to functional consequences. Antioxid Redox Signal 2011;15:551-589.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 551-589
-
-
Cyr, A.R.1
Domann, F.E.2
-
21
-
-
80053168829
-
Absence of effects of SIR2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvari M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila A-M, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D. Absence of effects of SIR2 overexpression on lifespan in C. elegans and Drosophila. Nature 2011;477:482-485.
-
(2011)
Nature
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvari, M.5
Piper, M.D.6
Hoddinott, M.7
Sutphin, G.L.8
Leko, V.9
McElwee, J.J.10
Vazquez-Manrique, R.P.11
Orfila, A.-M.12
Ackerman, D.13
Au, C.14
Vinti, G.15
Riesen, M.16
Howard, K.17
Neri, C.18
Bedalov, A.19
Kaeberlein, M.20
Soti, C.21
Partridge, L.22
Gems, D.23
more..
-
22
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY. The sirtuin SIRT6 regulates lifespan in male mice. Nature 2012;483:218-221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
23
-
-
84874721105
-
Evidence for a common mechanism of SIRT1 regulation by allosteric activators
-
Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJY, Armour SM, Michan S, Zhao H, Jiang Y, Sweitzer SM, Blum CA, Disch JS, Ng PY, Howitz KT, Rolo AP, Hamuro Y, Moss J, Perni RB, Ellis JL, Vlasuk GP, Sinclair DA. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science 2013;339: 1216-1219.
-
(2013)
Science
, vol.339
, pp. 1216-1219
-
-
Hubbard, B.P.1
Gomes, A.P.2
Dai, H.3
Li, J.4
Case, A.W.5
Considine, T.6
Riera, T.V.7
Lee, J.E.8
Lamming, D.W.9
Pentelute, B.L.10
Schuman, E.R.11
Stevens, L.A.12
Ling, A.J.Y.13
Armour, S.M.14
Michan, S.15
Zhao, H.16
Jiang, Y.17
Sweitzer, S.M.18
Blum, C.A.19
Disch, J.S.20
Ng, P.Y.21
Howitz, K.T.22
Rolo, A.P.23
Hamuro, Y.24
Moss, J.25
Perni, R.B.26
Ellis, J.L.27
Vlasuk, G.P.28
Sinclair, D.A.29
more..
-
24
-
-
80054746880
-
Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation
-
Lombard DB, Tishkoff DX, Bao J. Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation. Handb Exp Pharmacol 2011;206:163-188.
-
(2011)
Handb Exp Pharmacol
, vol.206
, pp. 163-188
-
-
Lombard, D.B.1
Tishkoff, D.X.2
Bao, J.3
-
25
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, De Cabo R, Sinclair DA. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004;305:390-392.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
26
-
-
78651468722
-
SIRT3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
-
Someya S, Yu W, Hallows WC, Xu J, Vann JM, Leeu-wenburgh C, Tanokura M, Denu JM, Prolla TA. SIRT3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell 2010; 143:802-812.
-
(2010)
Cell
, vol.143
, pp. 802-812
-
-
Someya, S.1
Yu, W.2
Hallows, W.C.3
Xu, J.4
Vann, J.M.5
Leeu-Wenburgh, C.6
Tanokura, M.7
Denu, J.M.8
Prolla, T.A.9
-
27
-
-
39649100868
-
Regulation of SIRT6 protein levels by nutrient availability
-
Kanfi Y, Shalman R, Peshti V, Pilosof SN, Gozlan YM, Pearson KJ, Lerrer B, Moazed D, Marine J-C, De Cabo R, Cohen HY. Regulation of SIRT6 protein levels by nutrient availability. FEBS Lett 2008;582:543-548.
-
(2008)
FEBS Lett
, vol.582
, pp. 543-548
-
-
Kanfi, Y.1
Shalman, R.2
Peshti, V.3
Pilosof, S.N.4
Gozlan, Y.M.5
Pearson, K.J.6
Lerrer, B.7
Moazed, D.8
Marine, J.-C.9
De Cabo, R.10
Cohen, H.Y.11
-
28
-
-
77955347446
-
Sirtuin 3, a new target of PGC-1a, plays an important role in the suppression of ROS and mitochondrial biogenesis
-
Kong X, Wang R, Xue Y, Liu X, Zhang H, Chen Y, Fang F, Chang Y. Sirtuin 3, a new target of PGC-1a, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 2010;5:e11707.
-
(2010)
PLoS One
, vol.5
-
-
Kong, X.1
Wang, R.2
Xue, Y.3
Liu, X.4
Zhang, H.5
Chen, Y.6
Fang, F.7
Chang, Y.8
-
29
-
-
79955768567
-
Peroxisome proliferator-activated receptor-c coactivator-1a controls transcription of the SIRT3 gene, an essential component of the thermogenic brown adipocyte phenotype
-
Giralt A, Hondares E, Villena JA, Ribas F, Díaz-Delfín J, Giralt M, Iglesias R, Villarroya F. Peroxisome proliferator-activated receptor-c coactivator-1a controls transcription of the SIRT3 gene, an essential component of the thermogenic brown adipocyte phenotype. J Biol Chem 2011;286:16958-16966.
-
(2011)
J Biol Chem
, vol.286
, pp. 16958-16966
-
-
Giralt, A.1
Hondares, E.2
Villena, J.A.3
Ribas, F.4
Díaz-Delfín, J.5
Giralt, M.6
Iglesias, R.7
Villarroya, F.8
-
30
-
-
34548627517
-
+ levels dictate cell survival
-
+ levels dictate cell survival. Cell 2007;130: 1095-1107.
-
(2007)
Cell
, vol.130
, pp. 1095-1107
-
-
Yang, H.1
Yang, T.2
Baur, J.A.3
Perez, E.4
Matsui, T.5
Carmona, J.J.6
Lamming, D.W.7
Souza-Pinto, N.C.8
Bohr, V.A.9
Rosenzweig, A.10
De Cabo, R.11
Sauve, A.A.12
Sinclair, D.A.13
-
31
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in car-diomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP. SIRT3 is a stress-responsive deacetylase in car-diomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 2008;28:6384-6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
32
-
-
84857628087
-
The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging
-
Sack MN. The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging. J Mol Cell Cardiol 2012;52:520-525.
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 520-525
-
-
Sack, M.N.1
-
33
-
-
77449120223
-
Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway
-
Pillai VB, Sundaresan NR, Kim G, Gupta M, Rajamohan SB, Pillai JB, Samant S, Ravindra PV, Isbatan A, Gupta MP. Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway. J Biol Chem 2010;285:3133-3144.
-
(2010)
J Biol Chem
, vol.285
, pp. 3133-3144
-
-
Pillai, V.B.1
Sundaresan, N.R.2
Kim, G.3
Gupta, M.4
Rajamohan, S.B.5
Pillai, J.B.6
Samant, S.7
Ravindra, P.V.8
Isbatan, A.9
Gupta, M.P.10
-
34
-
-
78649521247
-
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
-
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. 2010;12:662-667.
-
(2010)
Cell Metab.
, vol.12
, pp. 662-667
-
-
Qiu, X.1
Brown, K.2
Hirschey, M.D.3
Verdin, E.4
Chen, D.5
-
35
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 2009;119:2758-2771.
-
(2009)
J Clin Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
36
-
-
78650248160
-
Sirt3-mediated deacetylation of evo-lutionarily conserved lysine 122 regulates MnSOD activity in response to stress
-
Tao R, Coleman MC, Pennington D, Ozden O, Park S-H, Jiang H, Kim H-S, Flynn CR, Hill S, McDonald WH, Olivier AK, Spitz DR, Gius D. Sirt3-mediated deacetylation of evo-lutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol Cell 2010;40:893-904.
-
(2010)
Mol Cell
, vol.40
, pp. 893-904
-
-
Tao, R.1
Coleman, M.C.2
Pennington, D.3
Ozden, O.4
Park, S.-H.5
Jiang, H.6
Kim, H.-S.7
Flynn, C.R.8
Hill, S.9
McDonald, W.H.10
Olivier, A.K.11
Spitz, D.R.12
Gius, D.13
-
37
-
-
34250001450
-
DNA repair is limiting for haematopoietic stem cells during ageing
-
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 2007;447:686-690.
-
(2007)
Nature
, vol.447
, pp. 686-690
-
-
Nijnik, A.1
Woodbine, L.2
Marchetti, C.3
Dawson, S.4
Lambe, T.5
Liu, C.6
Rodrigues, N.P.7
Crockford, T.L.8
Cabuy, E.9
Vindigni, A.10
Enver, T.11
Bell, J.I.12
Slijepcevic, P.13
Goodnow, C.C.14
Jeggo, P.A.15
Cornall, R.J.16
-
38
-
-
34250007142
-
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
-
Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007;447:725-729.
-
(2007)
Nature
, vol.447
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
Nussenzweig, A.4
Hoeijmakers, J.5
Weissman, I.L.6
-
39
-
-
84874238886
-
SIRT3 reverses aging-associated degeneration
-
Brown K, Xie S, Qiu X, Mohrin M, Shin J, Liu Y, Zhang D, Scadden DT, Chen D. SIRT3 reverses aging-associated degeneration. Cell Rep 2013;3:319-327.
-
(2013)
Cell Rep
, vol.3
, pp. 319-327
-
-
Brown, K.1
Xie, S.2
Qiu, X.3
Mohrin, M.4
Shin, J.5
Liu, Y.6
Zhang, D.7
Scadden, D.T.8
Chen, D.9
-
40
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 2006;12:446-451.
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
41
-
-
39149086121
-
Stems cells and the pathways to aging and cancer
-
Rossi DJ, Jamieson CHM, Weissman IL. Stems cells and the pathways to aging and cancer. Cell 2008;132:681-696.
-
(2008)
Cell
, vol.132
, pp. 681-696
-
-
Rossi, D.J.1
Jamieson, C.H.M.2
Weissman, I.L.3
-
42
-
-
84874655208
-
Nrf2 regulates haematopoietic stem cell function
-
Tsai JJ, Dudakov JA, Takahashi K, Shieh J-H, Velardi E, Holland AM, Singer NV, West ML, Smith OM, Young LF, Shono Y, Ghosh A, Hanash AM, Tran HT, Moore MAS, Van den Brink MRM. Nrf2 regulates haematopoietic stem cell function. Nat Cell Biol 2013;15:309-316.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 309-316
-
-
Tsai, J.J.1
Dudakov, J.A.2
Takahashi, K.3
Shieh, J.-H.4
Velardi, E.5
Holland, A.M.6
Singer, N.V.7
West, M.L.8
Smith, O.M.9
Young, L.F.10
Shono, Y.11
Ghosh, A.12
Hanash, A.M.13
Tran, H.T.14
Moore, M.A.S.15
Van Den Brink, M.R.M.16
-
43
-
-
84872806231
-
Genome-wide methylation profiles reveal quantitative views of human aging rates
-
Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, Klotzle B, Bibikova M, Fan J-B, Gao Y, Deconde R, Chen M, Rajapakse I, Friend S, Ideker T, Zhang K. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell 2013;49:359-367.
-
(2013)
Mol Cell
, vol.49
, pp. 359-367
-
-
Hannum, G.1
Guinney, J.2
Zhao, L.3
Zhang, L.4
Hughes, G.5
Sadda, S.6
Klotzle, B.7
Bibikova, M.8
Fan, J.-B.9
Gao, Y.10
Deconde, R.11
Chen, M.12
Rajapakse, I.13
Friend, S.14
Ideker, T.15
Zhang, K.16
-
44
-
-
84874245684
-
The DNA methylome as a biomarker for epigenetic instability and human aging
-
Mendelsohn AR, Larrick JW. The DNA methylome as a biomarker for epigenetic instability and human aging. Rejuvenation Res 2013;16:74-77.
-
(2013)
Rejuvenation Res
, vol.16
, pp. 74-77
-
-
Mendelsohn, A.R.1
Larrick, J.W.2
-
45
-
-
77952940043
-
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1a in skeletal muscle
-
Palacios OM, Carmona JJ, Michan S, Chen KY, Manabe Y, III JLW, Goodyear LJ, Tong Q. Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1a in skeletal muscle. Aging (Albany NY) 2009;1:771-783.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 771-783
-
-
Palacios, O.M.1
Carmona, J.J.2
Michan, S.3
Chen, K.Y.4
Manabe, Y.5
Goodyear, L.J.6
Tong, Q.7
-
46
-
-
84872276165
-
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acet-ylome
-
Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ. Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acet-ylome. Mol Cell 2013;49:186-199.
-
(2013)
Mol Cell
, vol.49
, pp. 186-199
-
-
Hebert, A.S.1
Dittenhafer-Reed, K.E.2
Yu, W.3
Bailey, D.J.4
Selen, E.S.5
Boersma, M.D.6
Carson, J.J.7
Tonelli, M.8
Balloon, A.J.9
Higbee, A.J.10
Westphall, M.S.11
Pagliarini, D.J.12
Prolla, T.A.13
Assadi-Porter, F.14
Roy, S.15
Denu, J.M.16
Coon, J.J.17
-
47
-
-
65349128571
-
Disruption of the Ang II type 1 receptor promotes longevity in mice
-
Benigni A, Corna D, Zoja C, Sonzogni A, Latini R, Salio M, Conti S, Rottoli D, Longaretti L, Cassis P, Morigi M, Coff-man TM, Remuzzi G. Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 2009;119: 524-530.
-
(2009)
J Clin Invest
, vol.119
, pp. 524-530
-
-
Benigni, A.1
Corna, D.2
Zoja, C.3
Sonzogni, A.4
Latini, R.5
Salio, M.6
Conti, S.7
Rottoli, D.8
Longaretti, L.9
Cassis, P.10
Morigi, M.11
Coff-Man, T.M.12
Remuzzi, G.13
-
48
-
-
84869816787
-
A molecular mechanism for direct sirtuin activation by resveratrol
-
Gertz M, Nguyen GTT, Fischer F, Suenkel B, Schlicker C, Fränzel B, Tomaschewski J, Aladini F, Becker C, Wolters D, Steegborn C. A molecular mechanism for direct sirtuin activation by resveratrol. PloS One 2012;7:e49761.
-
(2012)
PloS One
, vol.7
-
-
Gertz, M.1
Nguyen, G.T.T.2
Fischer, F.3
Suenkel, B.4
Schlicker, C.5
Fränzel, B.6
Tomaschewski, J.7
Aladini, F.8
Becker, C.9
Wolters, D.10
Steegborn, C.11
-
49
-
-
84869221105
-
Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism
-
Buler M, Aatsinki S-M, Izzi V, Hakkola J. Metformin reduces hepatic expression of SIRT3, the mitochondrial deacetylase controlling energy metabolism. PloS One 2012;7.
-
(2012)
PloS One
, pp. 7
-
-
Buler, M.1
Aatsinki, S.-M.2
Izzi, V.3
Hakkola, J.4
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