Long-acting human serum albumin-thioredoxin fusion protein suppresses bleomycin-induced pulmonary fibrosis progression

Journal of Pharmacology and Experimental Therapeutics

Volumn 345, Issue 2, 2013, Pages 271-283

  Tanaka, Ryota ^a   Watanabe, Hiroshi ^a   Kodama, Azusa ^a   Chuang, Victor Tuan Giam ^b   Ishima, Yu ^a   Hamasaki, Keisuke ^a   Tanaka, Ken Ichiro ^c   Mizushima, Tohru ^c   Otagiri, Masaki ^d   Maruyama, Toru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b CURTIN UNIVERSITY   (Australia)

^c KEIO UNIVERSITY   (Japan)

^d SOJO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; HUMAN SERUM ALBUMIN THIOREDOXIN 1 FUSION PROTEIN; HYDROXYPROLINE; INTERLEUKIN 6; LONG ACTING DRUG; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DISEASE COURSE; DRUG DISTRIBUTION; DRUG RETENTION; FIBROSING ALVEOLITIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE PROGRESSION; HYDROXYPROLINE; INTERLEUKIN-6; LUNG; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MACROPHAGES; MALONDIALDEHYDE; MICE; NEUTROPHILS; PULMONARY FIBROSIS; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS; SERUM ALBUMIN; THIOREDOXINS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84876528883     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.201814     Document Type: Article

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