Improved pharmacokinetics of recombinant bispecific antibody molecules by fusion to human serum albumin

Journal of Biological Chemistry

Volumn 282, Issue 17, 2007, Pages 12650-12660

  Müller, Dafne ^a   Karle, Anette ^a,b   Meißburger, Bettina ^a   Höfig, Ines ^a,c   Stork, Roland ^a   Kontermann, Roland E ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; BIOACTIVITY; GENETIC ENGINEERING; PHARMACOKINETICS; SIGNAL TRANSDUCTION; TUMORS;

CARCINOEMBRYONIC ANTIGEN (CEA); LYMPHOCYTES; PHARMACOKINETIC PROPERTIES;

ANTIBODIES;

CARCINOEMBRYONIC ANTIGEN; CD3 ANTIGEN; HUMAN SERUM ALBUMIN; HYBRID PROTEIN; RECOMBINANT ANTIBODY; T LYMPHOCYTE RECEPTOR; BISPECIFIC ANTIBODY; SERUM ALBUMIN;

ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; T LYMPHOCYTE; ANIMAL; CELLULAR IMMUNITY; DRUG EFFECT; DRUG SCREENING; GENETICS; IMMUNOLOGY; MOUSE; NEOPLASM;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIGENS, CD3; CARCINOEMBRYONIC ANTIGEN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IMMUNITY, CELLULAR; MICE; NEOPLASMS; RECOMBINANT FUSION PROTEINS; SERUM ALBUMIN; T-LYMPHOCYTES;

EID: 34250361507     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700820200     Document Type: Article

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