Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 184, Issue 5, 2011, Pages 569-581

  Gibbons, Michael A ^a,b   MacKinnon, Alison C ^a   Ramachandran, Prakash ^a   Dhaliwal, Kevin ^a   Duffin, Rodger ^a   Phythian Adams, Alexander T ^c   Van Rooijen, Nico ^e   Haslett, Christopher ^a   Howie, Sarah E ^a   Simpson, A John ^a,g   Hirani, Nikhil ^a   Gauldie, Jack ^f   Iredale, John P ^a   Sethi, Tariq ^a,h   Forbes, Stuart J ^a,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL DEVON AND EXETER NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e VU UNIVERSITY AMSTERDAM   (Netherlands)

^f MCMASTER UNIVERSITY   (Canada)

^g NEWCASTLE UNIVERSITY   (United Kingdom)

^h KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antiinflammatory; Corticosteroids; Immune cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ARGINASE 1; CD163 ANTIGEN; COL1 PROTEIN; COLLAGEN; PROTEIN; UNCLASSIFIED DRUG; YM1 PROTEIN; BLEOMYCIN;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; FEMALE; FIBROGENESIS; FIBROSING ALVEOLITIS; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LUNG FIBROSIS; MACROPHAGE; MACROPHAGE ACTIVATION; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; ANIMAL; CELLULAR IMMUNITY; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DISEASE COURSE; DISEASE MODEL; GENETICS; IMMUNOLOGY; LUNG ALVEOLUS MACROPHAGE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; BLEOMYCIN; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNITY, CELLULAR; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MICE; MONOCYTES; PHENOTYPE; PULMONARY FIBROSIS;

EID: 80052371132     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201010-1719OC     Document Type: Article

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