Redox regulation of lung inflammation by thioredoxin

Antioxidants and Redox Signaling

Volumn 7, Issue 1-2, 2005, Pages 60-71

  Nakamura, Takayuki ^a   Nakamura, Hajime ^a   Hoshino, Tomoaki ^b   Ueda, Shugo ^a   Wada, Hiromi ^c   Yodoi, Junji ^c  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALLOPURINOL; ANTIOXIDANT; BLEOMYCIN; INTERLEUKIN 18; INTERLEUKIN 2; IODOXAMIC ACID; LAZEROID; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

AIRWAY; CATALYST; CELL ACTIVATION; CELL PROLIFERATION; CELL VIABILITY; GENE THERAPY; HUMAN; INFLUENZA; ISCHEMIA; LUNG PARENCHYMA; NONHUMAN; OXIDATION REDUCTION REACTION; PLASMA; PNEUMONIA; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; CATALYSIS; CYTOKINES; GENE THERAPY; HUMANS; INFLAMMATION; LUNG; LUNG DISEASES; MODELS, BIOLOGICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; THIOREDOXIN; TIME FACTORS;

EID: 13244253652     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.60     Document Type: Review

References (157)

1. Abdiu A, Nakamura H, Sahaf B, Yodoi J, Holmgren A, and Rosen A. Thioredoxin blood level increases after severe burn injury. Antioxid Redox Signal 2: 707-716, 2000.
2. Adkins WK and Taylor AE. Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung. J Appl Physiol 69: 2012-2018, 1990.
3. 2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice. J Clin Invest 85: 739-745, 1990.
4. Allison RC, Kyle J, Adkins WK, Prasad VR, McCord JM, and Taylor AE. Effect of ischemia reperfusion or hypoxia reoxygenation on lung vascular permeability and resistance. J Appl Physiol 69: 597-603, 1990.
5. Amari T, Kubo K, Kobayashi T, and Sekiguchi M. Effects of recombinant human superoxide dismutase on tumor necrosis factor-induced lung injury in awake sheep. J Appl Physiol 74: 2641-2648, 1993.
6. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161: 646-664, 2000.
7. Andoh T, Chock PB, and Chiueh CC. The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells. J Biol Chem 277: 9655-9660, 2002.
8. Antuni JD, Kharitonov SA, Hughes D, Hudson ME, and Barnes PJ. Increase in exhaled carbon monoxide during exacerbations of cystic fibrosis. Thorax 55: 138-142, 2000.
9. Aota M, Matsuda K, Isowa N, Wada H, Yodoi J, and Ban T. Protection against reperfusion-induced arrhythmias by human thioredoxin. J Cardiovasc Pharmacol 27: 727-732, 1996.
10. Arai M, Imai H, Koumura T, Yoshida M, Emoto K, Umeda M, Chiba N, and Nakagawa Y. Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells. J Biol Chem 274: 4924-4933, 1999.
11. Baird BR, Cheronis JC, Sandhaus RA, Berger EM, White CW, and Repine JE. O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs. J Appl Physiol 61: 2224-2229, 1986.
12. Baz MA, Tapson VF, Roggli VL, Van Trigt P, and Piantadosi CA. Glutathione depletion in epithelial lining fluid of lung allograft patients. Am J Respir Crit Care Med 153: 742-746, 1996.
13. Bertini R, Howard OM, Dong HF, Oppenheim JJ, Bizzarri C, Sergi R, Caselli G, Pagliei S, Romines B, Wilshire JA, Mengozzi M, Nakamura H, Yodoi J, Pekkari K, Gurunath R, Holmgren A, Herzenberg LA, and Ghezzi P. Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant forneutrophils, monocytes, and T cells. J Exp med 189: 1783-1789, 1999.
14. Bowler RP, Arcaroli J, Abraham E, Patel M, Chang LY, and Crapo JD. Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury. Am J Physiol Lung Cell Mol Physiol 284: L680-L687, 2003.
15. Brown LA. Glutathione protects signal transduction in type II cells under oxidant stress. Am J Physiol 266: L172-L177, 1994.
16. Bunnell E and Pacht ER. Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome. Am Rev Respir Dis 148: 1174-1178, 1993.
17. Cale AR, Ricagna F, Wiklund L, McGregor CG, and Miller VM. Mononuclear cells from dogs with acute lung allograft rejection cause contraction of pulmonary arteries. Circulation 90: 952-958, 1994.
18. Cantin AM, Hubbard RC, and Crystal RG. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. Am Rev Respir Dis 139: 370-372, 1989.
19. Carraway MS, Ghio AJ, Taylor JL, and Piantadosi CA. Induction of ferritin and heme oxygenase-1 by endotoxin in the lung. Am J Physiol 275: L583-L592, 1998.
20. Chabot F, Mitchell JA, Gutteridge JM, and Evans TW. Reactive oxygen species in acute lung injury. Eur Respir J 11: 745-757, 1998.
21. Chiueh C, Lee S, Andoh T, and Murphy D. Induction of antioxidative and antiapoptotic thioredoxin supports neuroprotective hypothesis of estrogen. Endocrine 21: 27-31, 2003.
22. 2-terminal kinase-mediated redox-dependent degradation of IkappaB: role of thioredoxin in NF-kappaB activation. J Biol Chem 276: 4662-4670, 2001.
23. Das KC and Das CK. Thioredoxin, a singlet oxygen quencher and hydroxyl radical scavenger: redox independent functions. Biochem Biophys Res Commun 277: 443-447, 2000.
24. Das KC, Lewis-Molock Y, and White CW. Elevation of manganese superoxide dismutase gene expression by thioredoxin. Am J Respir Cell Mol Biol 17: 713-726, 1997.
25. Das KC, Guo XL, and White CW. Induction of thioredoxin and thioredoxin reductase gene expression in lungs of newborn primates by oxygen. Am J Physiol 276: L530-L539, 1999.
26. Dekigai H, Nakamura H, Bai J, Tanito M, Masutani H, Hirota K, Matsui H, Murakami M, and Yodoi J. Geranylgeranylacetone promotes induction and secretion of thioredoxin in gastric mucosal cells and peripheral blood lymphocytes. Free Radic Res 35: 23-30, 2001.
27. DeMeo DL and Ginns LC. Clinical status of lung transplantation. Transplantation 72: 1713-1724, 2001.
28. Detterbeck FC, Keagy BA, Paull DE, and Wilcox BR. Oxygen free radical scavengers decrease reperfusion injury in lung transplantation. Ann Thorac Surg 50: 204-209; discussion 209-210, 1990.
29. Didier C, Kerblat I, Drouet C, Favier A, Beani JC, and Richard MJ. Induction of thioredoxin by ultraviolet-A radiation prevents oxidative-mediated cell death in human skin fibroblasts. Free Radic Biol Med 31: 585-598, 2001.
30. Doelman CJ, Leurs R, Oosterom WC, and Bast A. Mineral dust exposure and free radical-mediated lung damage. Exp Lung Res 16: 41-55, 1990.
31. Domenighetti G, Suter PM, Schaller MD, Ritz R, and Perret C. Treatment with N-acetylcysteine during acute respiratory distress syndrome: a randomized, double-blind, placebo-controlled clinical study. J Crit Care 12: 177-182, 1997.
32. Eppinger MJ, Deeb GM, Bolling SF, and Ward PA. Mediators of ischemia-reperfusion injury of rat lung. Am J Pathol 150: 1773-1784, 1997.
33. Ericson ML, Horling J, Wendel-Hansen V, Holmgren A, and Rosen A. Secretion of thioredoxin after in vitro activation of human B cells. Lymphokine Cytokine Res 11: 201-207, 1992.
34. Flick MR, Milligan SA, Hoeffel JM, and Goldstein IM. Catalase prevents increased lung vascular permeability during air emboli in unanesthetized sheep. J Appl Physiol 64: 929-935, 1988.
35. Freeman BA and Crapo JD. Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J Biol Chem 256: 10986-10992, 1981.
36. Fujii S, Nanbu Y, Nonogaki H, Konishi I, Mori T, Masutani H, and Yodoi J. Coexpression of adult T-cell leukemia-derived factor, a human thioredoxin homologue, and human papillomavirus DNA in neoplastic cervical squamous epithelium. Cancer 68: 1583-1591, 1991.
37. Fukuse T, Hirata T, Yokomise H, Hasegawa S, Inui K, Mitsui A, Hirakawa T, Hitomi S, Yodoi J, and Wada H. Attenuation of ischaemia reperfusion injury by human thioredoxin. Thorax 50: 387-391, 1995.
38. Gauntt CD, Ohira A, Honda O, Kigasawa K, Fujimoto T, Masutani H, Yodoi J, and Honda Y. Mitochondrial induction of adult T cell leukemia derived factor (ADF/hTx) after oxidative stresses in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 35: 2916-2923, 1994.
39. Gebel S and Muller T. The activity of NF-kappaB in Swiss 3T3 cells exposed to aqueous extracts of cigarette smoke is dependent on thioredoxin. Toxicol Sci 59: 75-81, 2001.
40. Gon Y, Sasada T, Matsui M, Hashimoto S, Takagi Y, Iwata S, Wada H, Horie T, and Yodoi J. Expression of thioredoxin in bleomycin-injured airway epithelium: possible role of protection against bleomycin induced epithelial injury. Life Sci 68: 1877-1888, 2001.
41. Haddad JJ. Oxygen homeostasis, thiol equilibrium and redox regulation of signalling transcription factors in the alveolar epithelium. Cell Signal 14: 799-810, 2002.
42. 2-evoked regulation of HIF-1alpha and NF-kappaB in perinatal lung epithelium requires glutathione biosynthesis. Am J Physiol Lung Cell Mol Physiol 278: L492-L503, 2000.
43. Hagen TM, Brown LA, and Jones DP. Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells. Biochem Pharmacol 35: 4537-4542, 1986.
44. Harper R, Wu K, Chang MM, Yoneda K, Pan R, Reddy SP, and Wu R. Activation of nuclear factor-kappa b transcriptional activity in airway epithelial cells by thioredoxin but not by N-acetyl-cysteine and glutathione. Am J Respir Cell Mol Biol 25: 178-185, 2001.
45. Hashimoto S, Matsumoto K, Gon Y, Furuichi S, Maruoka S, Takeshita I, Hirota K, Yodoi J, and Horie T. Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alpha. Biochem Biophys Res Commun 258: 443-447, 1999.
46. Hattori I, Takagi Y, Nakamura H, Nozaki K, Bai J, Kondo N, Sugino T, Nishimura M, Hashimoto N, and Yodoi J. Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice. Antioxid Redox Signal 6: 81-87, 2004.
47. Hausen B, Mueller P, Bahra M, Ramsamooj R, Morris RE, and Hewitt CW. Donor treatment with the lazeroid U74389G reduces ischemia-reperfusion injury in a rat lung transplant model. Ann Thorac Surg 64: 814-820, 1997.
48. Hayashi T, Ueno Y, and Okamoto T. Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin. J Biol Chem 268: 11380-11388, 1993.
49. Heffner JE and Repine JE. Pulmonary strategies of antioxidant defense. Am Rev Respir Dis 140: 531-554, 1989.
50. Hirota K, Matsui M, Iwata S, Nishiyama A, Mori K, and Yodoi J. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci U S A 94: 3633-3638, 1997.
51. Holmgren A. Thioredoxin. Annu Rev Biochem 54: 237-271, 1985.
52. Holmgren A. Thioredoxin and glutaredoxin systems. J Biol Chem 264: 13963-13966, 1989.
53. Horgan MJ, Lum H, and Malik AB. Pulmonary edema after pulmonary artery occlusion and reperfusion. Am Rev Respir Dis 140: 1421-1428, 1989.
54. Hori K, Katayama M, Sato N, Ishii K, Waga S, and Yodoi J. Neuroprotection by glial cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX). Brain Res 652: 304-310, 1994.
55. Horvath I, Donnelly LE, Kiss A, Paredi P, Kharitonov SA, and Barnes PJ. Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress. Thorax 53: 668-672, 1998.
56. Hoshino T, Nakamura H, Okamoto M, Kato S, Araya S, Nomiyama K, Oizumi K, Young HA, Aizawa H, and Yodoi J. Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury. Am J Respir Crit Care Med 168: 1075-1083, 2003.
57. Huang YC, Fisher PW, Nozik-Grayck E, and Piantadosi CA. Hypoxia compared with normoxia alters the effects of nitric oxide in ischemia-reperfusion lung injury. Am J Physiol 273: L504-L512, 1997.
58. Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, and Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275: 90-94, 1997.
59. Ishii Y, Hirano K, Morishima Y, Masuyama K, Goto Y, Nomura A, Sakamoto T, Uchida Y, Sagai M, and Sekizawa K. Early molecular and cellular events of oxidant-induced pulmonary fibrosis in rats. Toxicol Appl Pharmacol 167: 173-181, 2000.
60. Isowa N, Yoshimura T, Kosaka S, Liu M, Hitomi S, Yodoi J, and Wada H. Human thioredoxin attenuates hypoxia-reoxygenation injury of murine endothelial cells in a thiol-free condition. J Cell Physiol 182: 33-40, 2000.
61. Jackson RM and Veal CF. Effects of hypoxia and reoxygenation on lung glutathione system. Am J Physiol 259: H518-H524, 1990.
62. Jamieson DD, Kerr DR, and Unsworth I. Interaction of N-acetylcysteine and bleomycin on hyperbaric oxygen-induced lung damage in mice. Lung 165: 239-247, 1987.
63. Kalayoglu M, Sollinger HW, Stratta RJ, D'Alessandro AM, Hoffmann RM, Pirsch JD, and Belzer FO. Extended preservation of the liver for clinical transplantation. Lancet 1: 617-619, 1988.
64. Kasuno K, Nakamura H, Ono T, Muso E, and Yodoi J. Protective roles of thioredoxin, a redox-regulating protein, in renal ischemia/reperfusion injury. Kidney Int 64: 1273-1282, 2003.
65. Kawashima M, Bando T, Nakamura T, Isowa N, Liu M, Toyokuni S, Hitomi S, and Wada H. Cytoprotective effects of nitroglycerin in ischemia-reperfusion- induced lung injury. Am J Respir Crit Care Med 161: 935-943, 2000.
66. Kelly FJ. Free radical disorders of preterm infants. Br Med Bull 49: 668-678, 1993.
67. Kennedy TP, Rao NV, Hopkins C, Pennington L, Tolley E, and Hoidal JR. Role of reactive oxygen species in reperfusion injury of the rabbit lung. J Clin Invest 83: 1326-1335, 1989.
68. Kinnula VL. Oxidant and antioxidant mechanisms of lung disease caused by asbestos fibres. Eur Respir J 14: 706-716, 1999.
69. Kirk AJ, Colquhoun IW, and Dark JH. Lung preservation: a review of current practice and future directions. Ann Thorac Surg 56: 990-100, 1993.
70. Koike E, Hirano S, Shimojo N, and Kobayashi T. cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles. Toxicol Sci 67: 241-246, 2002.
71. Kondo N, Ishii Y, Kwon YW, Tanito M, Horita H, Nishinaka Y, Nakamura H, and Yodoi J. Redox-sensing release of human thioredoxin from T lymphocytes with negative feedback loops. J Immunol 172: 442-448, 2004.
72. Koura T, Gon Y, Hashimoto S, Azuma A, Kudoh S, Fukuda Y, Sugawara I, Yodoi J, and Horie T. Expression of thioredoxin in granulomas of sarcoidosis: possible role in the development of T lymphocyte activation. Thorax 55: 755-761, 2000.
73. Kozower BD, Christofidou-Solomidou M, Sweitzer TD, Muro S, Buerk DG, Solomides CC, Albelda SM, Patterson GA, and Muzykantov VR. Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury. Nat Biotechnol 21: 392-398, 2003.
74. Laurent TC, Moore EC, and Reichard P. Enzymatic synthesis of deoxyribonucleotides. IV. Isolation and characterization of thioredoxin, the hydrogen donor from Escherichia coli B. J Biol Chem 239: 3436-3444, 1964.
75. Lee PJ, Alam J, Sylvester SL, Inamdar N, Otterbein L, and Choi AM. Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. Am J Respir Cell Mol Biol 14: 556-568, 1996.
76. Lynch MJ, Grum CM, Gallagher KP, Bolling SF, Deeb GM, and Morganroth ML. Xanthine oxidase inhibition attenuates ischemic-reperfusion lung injury. J Surg Res 44: 538-544, 1988.
77. MacNee W. Oxidants/antioxidants and COPD. Chest 117: 303S-317S, 2000.
78. MacNee W and Rahman I. Oxidants/antioxidants in idiopathic pulmonary fibrosis. Thorax 50 Suppl 1: S53-S58, 1995.
79. Madden MC, Richards JH, Dailey LA, Hatch GE, and Ghio AJ. Effect of ozone on diesel exhaust particle toxicity in rat lung. Toxicol Appl Pharmacol 168: 140-148, 2000.
80. Maeda H and Akaike T. Oxygen free radicals as pathogenic molecules in viral diseases. Proc Soc Exp Biol Med 198: 721-727, 1991.
81. Maestrelli P, El Messlemani AH, De Fina O, Nowicki Y, Saetta M, Mapp C, and Fabbri LM. Increased expression of heme oxygenase (HO)-1 in alveolar spaces and HO-2 in alveolar walls of smokers. Am J Respir Crit Care Med 164: 1508-1513, 2001.
82. Magi B, Bini L, Perari MG, Fossi A, Sanchez JC, Hochstrasser D, Paesano S, Raggiaschi R, Santucci A, Pallini V, and Rottoli P. Bronchoalveolar lavage fluid protein composition in patients with sarcoidosis and idiopathic pulmonary fibrosis: a two-dimensional electrophoretic study. Electrophoresis 23: 3434-3444, 2002.
83. Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37: 517-554, 1997.
84. Mastruzzo C, Crimi N, and Vancheri C. Role of oxidative stress in pulmonary fibrosis. Monaldi Arch Chest Dis 57: 173-176, 2002.
85. 2-induced interleukin-8 production from human alveolar epithelial cells. Cytokine 18: 266-273, 2002.
86. Matthews JR, Wakasugi N, Virelizier JL, Yodoi J, and Hay RT. Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res 20: 3821-3830, 1992.
87. Moine P, McIntyre R, Schwartz MD, Kaneko D, Shenkar R, Le Tulzo Y, Moore EE, and Abraham E. NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome. Shock 13: 85-91, 2000.
88. Morse D. The role of heme oxygenase-1 in pulmonary fibrosis. Am J Respir Cell Mol Biol 29: S82-S86, 2003.
89. Muro K, Go T, Hirata T, Fukuse T, Yokomise H, Inui K, Yodoi J, Hitomi S, and Wada H. Expression of the adult T-cell leukemia-derived factor, human thioredoxin, in the allotransplanted canine lung. Surg Today 25: 626-632, 1995.
90. Nagahiro I, Yano M, Boasquevisque CH, Fujino S, Cooper JD, and Patterson GA. Vasoactive intestinal peptide ameliorates reperfusion injury in rat lung transplantation. J Heart Lung Transplant 17: 617-621, 1998.
91. Nakamura H, Masutani H, Tagaya Y, Yamauchi A, Inamoto T, Nanbu Y, Fujii S, Ozawa K, and Yodoi J. Expression and growth-promoting effect of adult T-cell leukemia-derived factor. A human thioredoxin homologue in hepatocellular carcinoma. Cancer 69: 2091-2097, 1992.
92. Nakamura H, Matsuda M, Furuke K, Kitaoka Y, Iwata S, Toda K, Inamoto T, Yamaoka Y, Ozawa K, and Yodoi J. Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett 42: 75-80, 1994.
93. Nakamura H, De Rosa S, Roederer M, Anderson MT, Dubs JG, Yodoi J, Holmgren A, and Herzenberg LA. Elevation of plasma thioredoxin levels in HIV-infected individuals. Int Immunol 8: 603-611, 1996.
94. Nakamura H, Nakamura K, and Yodoi J. Redox regulation of cellular activation. Annu Rev Immunol 15: 351-369, 1997.
95. Nakamura H, Vaage J, Valen G, Padilla CA, Bjornstedt M, and Holmgren A. Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery. Free Radic Biol Med 24: 1176-1186, 1998.
96. Nakamura H, De Rosa SC, Yodoi J, Holmgren A, Ghezzi P, and Herzenberg LA. Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS. Proc Natl Acad Sci U S A 98: 2688-2693, 2001.
97. Nakamura H, Herzenberg LA, Bai J, Araya S, Kondo N, Nishinaka Y, and Yodoi J. Circulating thioredoxin suppresses lipopolysaccharide-induced neutrophil chemotaxis. Proc Natl Acad Sci U S A 98: 15143-15148, 2001.
98. Nakamura H, Tamura S, Watanabe I, Iwasaki T, and Yodoi J. Enhanced resistancy of thioredoxin-transgenic mice against influenza virus-induced pneumonia. Immunol Lett 82: 165-170, 2002.
99. Nakao A, Fujii M, Matsumura R, Kumano K, Saito Y, Miyazono K, and Iwamoto I. Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice. J Clin Invest 104: 5-11, 1999.
100. Nishinaka Y, Nishiyama A, Masutani H, Oka S, Ahsan KM, Nakayama Y, Ishii Y, Nakamura H, Maeda M, and Yodoi J. Loss of thioredoxin binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: implications for adult T-cell leukemia leukemogenesis. Cancer Res 64: 1287-1292, 2004.
101. Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, and Yodoi J. Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression. J Biol Chem 274: 21645-21650, 1999.
102. Nishiyama A, Ohno T, Iwata S, Matsui M, Hirota K, Masutani H, Nakamura H, and Yodoi J. Demonstration of the interaction of thioredoxin with p40phox, a phagocyte oxidase component, using a yeast two-hybrid system. Immunol Lett 68: 155-159, 1999.
103. Oberle S, Schwartz P, Abate A, and Schroder H. The antioxidant defense protein ferritin is a novel and specific target for pentaerithrityl tetranitrate in endothelial cells. Biochem Biophys Res Commun 261: 28-34, 1999.
104. Oda T, Akaike T, Hamamoto T, Suzuki F, Hirano T, and Maeda H. Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD. Science 244: 974-976, 1989.
105. O'Donovan DJ, Katkin JP, Tamura T, Husser R, Xu X, Smith CV, and Welty SE. Gene transfer of mitochondrially targeted glutathione reductase protects H441 cells from t-butyl hydroperoxide-induced oxidant stresses. Am J Respir Cell Mol Biol 20: 256-263, 1999.
106. O'Donovan DJ, Katkin JP, Tamura T, Smith CV, and Welty SE. Attenuation of hyperoxia-induced growth inhibition in H441 cells by gene transfer of mitochondrially targeted glutathione reductase. Am J Respir Cell Mol Biol 22: 732-738, 2000.
107. Ohira A, Honda O, Gauntt CD, Yamamoto M, Hori K, Masutani H, Yodoi J, and Honda Y. Oxidative stress induces adult T cell leukemia derived factor/thioredoxin in the rat retina. Lab Invest 70: 279-285, 1994.
108. Okada M, Maeda M, Tagaya Y, Taniguchi Y, Teshigawara K, Yoshiki T, Diamantstein T, Smith KA, Uchiyama T, and Honjo T. TCGF(IL 2)-receptor inducing factor(s). II. Possible role of ATL-derived factor (ADF) on constitutive IL 2 receptor expression of HTLV-I(+) T cell lines. J Immunol 135: 3995-4003, 1985.
109. Okamoto M, Kato S, Oizumi K, Kinoshita M, Inoue Y, Hoshino K, Akira S, McKenzie AN, Young HA, and Hoshino T. Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia. Blood 99: 1289-1298, 2002.
110. Okubo K, Kosaka S, Isowa N, Hirata T, Hitomi S, Yodoi J, Nakano M, and Wada H. Amelioration of ischemia-reperfusion injury by human thioredoxin in rabbit lung. J Thorac Cardiovasc Surg 113: 1-9, 1997.
111. Ono N, Yokomise H, Muro K, Inui K, Hitomi S, Yodoi J, and Wada H. Expression of adult T-cell leukemia-derived factor in bronchoalveolar lavage cells after canine lung transplantation. J Thorac Cardiovasc Surg 110: 15-21, 1995.
112. Otterbein LE and Choi AM. Heme oxygenase: colors of defense against cellular stress. Am J Physiol Lung Cell Mol Physiol 279: L1029-L1037, 2000.
113. Otterbein LE, Kolls JK, Mantell LL, Cook JL, Alam J, and Choi AM. Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103: 1047-1054, 1999.
114. Otterbein LE, Mantell LL, and Choi AM. Carbon monoxide provides protection against hyperoxic lung injury. Am J Physiol 276: L688-L694, 1999.
115. Ozdulger A, Cinel I, Koksel O, Cinel L, Avlan D, Unlu A, Okcu H, Dikmengil M, and Oral U. The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model. Shock 19: 366-372, 2003.
116. Piguet PF, Collart MA, Grau GE, Kapanci Y, and Vassalli P. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med 170: 655-663, 1989.
117. Quinlan GJ, Evans TW, and Gutteridge JM. Iron and the redox status of the lungs. Free Radic Biol Med 33: 1306-1313, 2002.
118. Rahman I and MacNee W. Oxidative stress and regulation of glutathione in lung inflammation. Eur Respir J 16: 534-554, 2000.
119. Rahman I and MacNee W. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radic Biol Med 28: 1405-1420, 2000.
120. Rahman I, Skwarska E, Henry M, Davis M, O'Connor CM, FitzGerald MX, Greening A, and MacNee W. Systemic and pulmonary oxidative stress in idiopathic pulmonary fibrosis. Free Radic Biol Med 27: 60-68, 1999.
121. Rahman I, Mulier B, Gilmour PS, Watchorn T, Donaldson K, Jeffery PK, and MacNee W. Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB. Biochem Pharmacol 62: 787-794, 2001.
122. Reid D, Snell G, Ward C, Krishnaswamy R, Ward R, Zheng L, Williams T, and Walters H. Iron overload and nitric oxide-derived oxidative stress following lung transplantation. J Heart Lung Transplant 20: 840-849, 2001.
123. Rhee SG, Kim KH, Chae HZ, Yim MB, Uchida K, Netto LE, and Stadtman ER. Antioxidant defense mechanisms: a new thiol-specific antioxidant enzyme. Ann N Y Acad Sci 738: 86-92, 1994.
124. Roum JH, Buhl R, McElvaney NG, Borok Z, and Crystal RG. Systemic deficiency of glutathione in cystic fibrosis. J Appl Physiol 75: 2419-2424, 1993.
125. Roum JH, Borok Z, McElvaney NG, Grimes GJ, Bokser AD, Buhl R, and Crystal RG. Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis. J Appl Physiol 87: 438-443, 1999.
126. Rubartelli A, Bajetto A, Allavena G, Wollman E, and Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem 267: 24161-24164, 1992.
127. Sachi Y, Hirota K, Masutani H, Toda K, Okamoto T, Takigawa M, and Yodoi J. Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells. Immunol Lett 44: 189-193, 1995.
128. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17: 2596-2606, 1998.
129. Sasada T, Iwata S, Sato N, Kitaoka Y, Hirota K, Nakamura K, Nishiyama A, Taniguchi Y, Takabayashi A, and Yodoi J. Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity. J Clin Invest 97: 2268-2276, 1996.
130. Schenk H, Vogt M, Droge W, and Schulze-Osthoff K. Thioredoxin as a potent costimulus of cytokine expression. J Immunol 156: 765-771, 1996.
131. Semenza GL. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88: 1474-1480, 2000.
132. Shioji K, Kishimoto C, Nakamura H, Masutani H, Yuan Z, Oka S, and Yodoi J. Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity. Circulation 106: 1403-1409, 2002.
133. Smith LL. The response of the lung to foreign compounds that produce free radicals. Annu Rev Physiol 48: 681-692, 1986.
134. Stewart KC and Patterson GA. Current trends in lung transplantation. Am J Transplant 1: 204-210, 2001.
135. Sumida Y, Nakashima T, Yoh T, Nakajima Y, Ishikawa H, Mitsuyoshi H, Sakamoto Y, Okanoue T, Kashima K, Nakamura H, and Yodoi J. Serum thioredoxin levels as an indicator of oxidative stress in patients with hepatitis C virus infection. J Hepatol 33: 616-622, 2000.
136. Suttner DM, Sridhar K, Lee CS, Tomura T, Hansen TN, and Dennery PA. Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells. Am J Physiol 276: L443-L451, 1999.
137. Suzuki T, Takahashi T, Yamasaki A, Fujiwara T, Hirakawa M, and Akagi R. Tissue-specific gene expression of heme oxygenase-1 (HO-1) and non-specific delta-aminolevulinate synthase (ALAS-N) in a rat model of septic multiple organ dysfunction syndrome. Biochem Pharmacol 60: 275-283, 2000.
138. Suzuki Y, Tanigaki T, Heimer D, Wang WZ, Ross WG, Sussman HH, and Raffin TA. Polyethylene glycol-conjugated superoxide dismutase attenuates septic lung injury in guinea pigs. Am Rev Respir Dis 145: 388-393, 1992.
139. Tagaya Y, Maeda Y, Mitsui A, Kondo N, Matsui H, Hamuro J, Brown N, Arai K, Yokota T, Wakasugi H, and Yodoi J. ATL-deived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction. EMBO J 8: 757-764, 1989.
140. Takagi Y, Mitsui A, Nishiyama A, Nozaki K, Sono H, Gon Y, Hashimoto N, and Yodoi J. Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage. Proc Natl Acad Sci U S A 96: 4131-4136, 1999.
141. Takeyoshi I, Iwanami K, Kamoshita N, Takahashi T, Kobayashi J, Tomizawa N, Kawashima Y, Matsumoto K, and Morishita Y. Effect of lazaroid U-74389G on pulmonary ischemia-reperfusion injury in dogs. J Invest Surg 14: 83-92, 2001.
142. Tamagawa K, Taooka Y, Maeda A, Hiyama K, Ishioka S, and Yamakido M. Inhibitory effects of a lecithinized superoxide dismutase on bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med 161: 1279-1284, 2000.
143. Tanito M, Masutani H, Nakamura H, Ohira A, and Yodoi J. Cytoprotective effect of thioredoxin against retinal photic injury in mice. Invest Ophthalmol Vis Sci 43: 1162-1167, 2002.
144. Thannickal VJ and Fanburg BL. Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 279: L1005-L1028, 2000.
145. Tomimoto H, Akiguchi I, Wakita H, Kimura J, Hori K, and Yodoi J. Astroglial expression of ATL-derived factor, a human thioredoxin homologue, in the gerbil brain after transient global ischemia. Brain Res 625: 1-8, 1993.
146. Trulock EP, Edwards LB, Taylor DO, Boucek MM, Mohacsi PJ, Keck BM, and Hertz MI. The Registry of the International Society for Heart and Lung Transplantation: Twentieth Official Adult Lung and Heart-Lung Transplant Report-2003. J Heart Lung Transplant 22: 625-635, 2003.
147. Ueda S, Masutani H, Nakamura H, Tanaka T, Ueno M, and Yodoi J. Redox control of cell death. Antioxid Redox Signal 4: 405-414, 2002.
148. Wada H, Hirata T, Decampos KN, Hitomi S, and Slutsky AS. Effect of the combination of human thioredoxin and L-cysteine on ischemia-reperfusion injury in isolated rat lungs. Eur Surg Res 27: 363-370, 1995.
149. Wada H, Muro K, Hirata T, Yodoi J, and Hitomi S. Rejection and expression of thioredoxin in transplanted canine lung. Chest 108: 810-814, 1995.
150. Yagi K, Liu C, Bando T, Yokomise H, Inui K, Hitomi S, and Wada H. Inhibition of reperfusion injury by human thioredoxin (adult T-cell leukemia-derived factor) in canine lung transplantation. J Thorac Cardiovasc Surg 108: 913-921, 1994.
151. Yamada Y, Nakamura H, Adachi T, Sannohe S, Oyamada H, Kayaba H, Yodoi J, and Chihara J. Elevated serum levels of thioredoxin in patients with acute exacerbation of asthma. Immunol Lett 86: 199-205, 2003.
152. Yamamoto M, Sato N, Tajima H, Furuke K, Ohira A, Honda Y, and Yodoi J. Induction of human thioredoxin in cultured human retinal pigment epithelial cells through cyclic AMP-dependent pathway; involvement in the cytoprotective activity of prostaglandin E1. Exp Eye Res 65: 645-652, 1997.
153. Yesilkaya A, Altinayak R, and Korgun DK. The antioxidant effect of free bilirubin on cumene-hydroperoxide treated human leukocytes. Gen Pharmacol 35: 17-20, 2000.
154. Yodoi J and Tursz T. ADF, a growth-promoting factor derived from adult T cell leukemia and homologous to thioredoxin: involvement in lymphocyte immortalization by HTLV-1 and EBV. Adv Cancer Res 57: 381-411, 1991.
155. Yodoi J and Uchiyama T. Diseases associated with HTLV-1: virus, IL-2 receptor dysregulation and redox regulation. Immunol Today 13: 405-411, 1992.
156. Yodoi J, Uchiyama T, Tsudo M, Wano Y, Teshigawara K, Okada M, and Maeda M. Abnormal expression of IL2 receptor/Tac antigen in ATL: The possible role of ATL-derived factor enhancing IL2 receptor expression. In: Manipulation of Host Defense Mechanism, edited by Aoki T, Tsubura E, and Urushizaki I. Amsterdam: Excerpta Medica, 1983, pp. 104-114.
157. Yokomise H, Fukuse T, Hirata T, Ohkubo K, Go T, Muro K, Yagi K, Inui K, Hitomi S, Mitsui A, and Yodoi J. Effect of recombinant human adult T cell leukemia-derived factor on rat lung reperfusion injury. Respiration 61: 99-104, 1994.