-
1
-
-
84860378895
-
The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma
-
22411914 10.1093/neuonc/nos002 1:CAS:528:DC%2BC38Xhtl2hsLbE
-
Andolfo I, Liguori L, De Antonellis P, Cusanelli E, Marinaro F, Pistollato F, Garzia L, De Vita G, Petrosino G, Accordi B, Migliorati R, Basso G, Iolascon A, Cinalli G, Zollo M (2012) The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma. Neuro-Oncology 14:596-612
-
(2012)
Neuro-Oncology
, vol.14
, pp. 596-612
-
-
Andolfo, I.1
Liguori, L.2
De Antonellis, P.3
Cusanelli, E.4
Marinaro, F.5
Pistollato, F.6
Garzia, L.7
De Vita, G.8
Petrosino, G.9
Accordi, B.10
Migliorati, R.11
Basso, G.12
Iolascon, A.13
Cinalli, G.14
Zollo, M.15
-
2
-
-
81555210945
-
Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells
-
22027557 10.4161/cbt.12.10.17681 1:CAS:528:DC%2BC38Xjs1ymtbk%3D
-
Babar IA, Czochor J, Steinmetz A, Weidhaas JB, Glazer PM, Slack FJ (2011) Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells. Cancer Biol Ther 12:908-914
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 908-914
-
-
Babar, I.A.1
Czochor, J.2
Steinmetz, A.3
Weidhaas, J.B.4
Glazer, P.M.5
Slack, F.J.6
-
3
-
-
84870940346
-
Developmental pathways in colon cancer: Crosstalk between WNT, BMP, Hedgehog and Notch
-
Bertrand FE, Angus CW, Partis WJ, Sigounas G (2012) Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch. Cell Cycle 11(23):4344-4351
-
(2012)
Cell Cycle
, vol.11
, Issue.23
, pp. 4344-4351
-
-
Bertrand, F.E.1
Angus, C.W.2
Partis, W.J.3
Sigounas, G.4
-
5
-
-
33751099034
-
RNAi therapeutics: A potential new class of pharmaceutical drugs
-
17108989 10.1038/nchembio839 1:CAS:528:DC%2BD28Xht1SrtLfO
-
Bumcrot D, Manoharan M, Koteliansky V, Sah DW (2006) RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat Chem Biol 2:711-719
-
(2006)
Nat Chem Biol
, vol.2
, pp. 711-719
-
-
Bumcrot, D.1
Manoharan, M.2
Koteliansky, V.3
Sah, D.W.4
-
6
-
-
33750370444
-
MicroRNA signatures in human cancers
-
17060945 10.1038/nrc1997 1:CAS:528:DC%2BD28XhtFWhs7fM
-
Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
7
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
12434020 10.1073/pnas.242606799 1:CAS:528:DC%2BD3sXjvVOl
-
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 99:15524-15529
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
Aldler, H.7
Rattan, S.8
Keating, M.9
Rai, K.10
Rassenti, L.11
Kipps, T.12
Negrini, M.13
Bullrich, F.14
Croce, C.M.15
-
8
-
-
27244434788
-
A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
16251535 10.1056/NEJMoa050995 1:CAS:528:DC%2BD2MXhtFKrtLbJ
-
Calin GA, Ferracin M, Cimmino A, Di Leva G, Shimizu M, Wojcik SE, Iorio MV, Visone R, Sever NI, Fabbri M, Iuliano R, Palumbo T, Pichiorri F, Roldo C, Garzon R, Sevignani C, Rassenti L, Alder H, Volinia S, Liu CG, Kipps TJ, Negrini M, Croce CM (2005) A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353:1793-1801
-
(2005)
N Engl J Med
, vol.353
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
Di Leva, G.4
Shimizu, M.5
Wojcik, S.E.6
Iorio, M.V.7
Visone, R.8
Sever, N.I.9
Fabbri, M.10
Iuliano, R.11
Palumbo, T.12
Pichiorri, F.13
Roldo, C.14
Garzon, R.15
Sevignani, C.16
Rassenti, L.17
Alder, H.18
Volinia, S.19
Liu, C.G.20
Kipps, T.J.21
Negrini, M.22
Croce, C.M.23
more..
-
9
-
-
0036752785
-
RNAi in human cells: Basic structural and functional features of small interfering RNA
-
12408823 10.1016/S1097-2765(02)00652-4 1:CAS:528:DC%2BD38XnvFSlt7k%3D
-
Chiu YL, Rana TM (2002) RNAi in human cells: basic structural and functional features of small interfering RNA. Mol Cell 10:549-561
-
(2002)
Mol Cell
, vol.10
, pp. 549-561
-
-
Chiu, Y.L.1
Rana, T.M.2
-
10
-
-
0038606999
-
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
-
12771196 10.1093/nar/gkg393 1:CAS:528:DC%2BD3sXkt1Wqsbo%3D
-
Czauderna F, Fechtner M, Dames S, Aygun H, Klippel A, Pronk GJ, Giese K, Kaufmann J (2003) Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res 31:2705-2716
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2705-2716
-
-
Czauderna, F.1
Fechtner, M.2
Dames, S.3
Aygun, H.4
Klippel, A.5
Pronk, G.J.6
Giese, K.7
Kaufmann, J.8
-
11
-
-
84857204034
-
Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells
-
22172337 10.1158/1541-7786.MCR-11-0296 1:CAS:528:DC%2BC38XjtFahs74%3D
-
Danza G, Di Serio C, Rosati F, Lonetto G, Sturli N, Kacer D, Pennella A, Ventimiglia G, Barucci R, Piscazzi A, Prudovsky I, Landriscina M, Marchionni N, Tarantini F (2012) Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells. Mol Cancer Res 10:230-238
-
(2012)
Mol Cancer Res
, vol.10
, pp. 230-238
-
-
Danza, G.1
Di Serio, C.2
Rosati, F.3
Lonetto, G.4
Sturli, N.5
Kacer, D.6
Pennella, A.7
Ventimiglia, G.8
Barucci, R.9
Piscazzi, A.10
Prudovsky, I.11
Landriscina, M.12
Marchionni, N.13
Tarantini, F.14
-
12
-
-
80052632447
-
MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma
-
21931765 10.1371/journal.pone.0024584
-
de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, Carotenuto M, Bello A, Formiggini F, Galeone A, De Rosa G, Virgilio A, Scognamiglio I, Sciro M, Basso G, Schulte JH, Cinalli G, Iolascon A, Zollo M (2011) MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma. PLoS One 6:e24584
-
(2011)
PLoS One
, vol.6
-
-
De Antonellis, P.1
Medaglia, C.2
Cusanelli, E.3
Andolfo, I.4
Liguori, L.5
De Vita, G.6
Carotenuto, M.7
Bello, A.8
Formiggini, F.9
Galeone, A.10
De Rosa, G.11
Virgilio, A.12
Scognamiglio, I.13
Sciro, M.14
Basso, G.15
Schulte, J.H.16
Cinalli, G.17
Iolascon, A.18
Zollo, M.19
-
13
-
-
3242677639
-
SiRNAs: Applications in functional genomics and potential as therapeutics
-
15060527 10.1038/nrd1345 1:CAS:528:DC%2BD2cXis1Gkt74%3D
-
Dorsett Y, Tuschl T (2004) siRNAs: applications in functional genomics and potential as therapeutics. Nat Rev Drug Discov 3:318-329
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
14
-
-
77950292495
-
Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model
-
20197467 10.1158/0008-5472.CAN-09-3114 1:CAS:528:DC%2BC3cXjtFygtbs%3D
-
Efferson CL, Winkelmann CT, Ware C, Sullivan T, Giampaoli S, Tammam J, Patel S, Mesiti G, Reilly JF, Gibson RE, Buser C, Yeatman T, Coppola D, Winter C, Clark EA, Draetta GF, Strack PR, Majumder PK (2010) Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model. Cancer Res 70:2476-2484
-
(2010)
Cancer Res
, vol.70
, pp. 2476-2484
-
-
Efferson, C.L.1
Winkelmann, C.T.2
Ware, C.3
Sullivan, T.4
Giampaoli, S.5
Tammam, J.6
Patel, S.7
Mesiti, G.8
Reilly, J.F.9
Gibson, R.E.10
Buser, C.11
Yeatman, T.12
Coppola, D.13
Winter, C.14
Clark, E.A.15
Draetta, G.F.16
Strack, P.R.17
Majumder, P.K.18
-
15
-
-
33645294070
-
Oncomirs - MicroRNAs with a role in cancer
-
16557279 10.1038/nrc1840 1:CAS:528:DC%2BD28XivVyqtrs%3D
-
Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6:259-269
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
16
-
-
84861866572
-
The mechanics of miRNA-mediated gene silencing: A look under the hood of miRISC
-
22664986 10.1038/nsmb.2296 1:CAS:528:DC%2BC38XotVWhtLw%3D
-
Fabian MR, Sonenberg N (2012) The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol 19:586-593
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 586-593
-
-
Fabian, M.R.1
Sonenberg, N.2
-
17
-
-
84858285411
-
MiR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia
-
22374871 10.1002/ajh.23129 1:CAS:528:DC%2BC38Xjs1Wqtrc%3D
-
Favreau AJ, Cross EL, Sathyanarayana P (2012) miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia. Am J Hematol 87:442-446
-
(2012)
Am J Hematol
, vol.87
, pp. 442-446
-
-
Favreau, A.J.1
Cross, E.L.2
Sathyanarayana, P.3
-
18
-
-
80053040376
-
Phase i trial of MK-0752 in children with refractory CNS malignancies: A pediatric brain tumor consortium study
-
21825264 10.1200/JCO.2011.35.7806 1:CAS:528:DC%2BC3MXhtlWqsLrO
-
Fouladi M, Stewart CF, Olson J, Wagner LM, Onar-Thomas A, Kocak M, Packer RJ, Goldman S, Gururangan S, Gajjar A, Demuth T, Kun LE, Boyett JM, Gilbertson RJ (2011) Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study. J Clin Oncol 29:3529-3534
-
(2011)
J Clin Oncol
, vol.29
, pp. 3529-3534
-
-
Fouladi, M.1
Stewart, C.F.2
Olson, J.3
Wagner, L.M.4
Onar-Thomas, A.5
Kocak, M.6
Packer, R.J.7
Goldman, S.8
Gururangan, S.9
Gajjar, A.10
Demuth, T.11
Kun, L.E.12
Boyett, J.M.13
Gilbertson, R.J.14
-
19
-
-
50149101511
-
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
-
18695239 10.1073/pnas.0805434105 1:CAS:528:DC%2BD1cXhtVCnurjK
-
Frank-Kamenetsky M, Grefhorst A, Anderson NN, Racie TS, Bramlage B, Akinc A, Butler D, Charisse K, Dorkin R, Fan Y, Gamba-Vitalo C, Hadwiger P, Jayaraman M, John M, Jayaprakash KN, Maier M, Nechev L, Rajeev KG, Read T, Rohl I, Soutschek J, Tan P, Wong J, Wang G, Zimmermann T, de Fougerolles A, Vornlocher HP, Langer R, Anderson DG, Manoharan M, Koteliansky V, Horton JD, Fitzgerald K (2008) Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc Natl Acad Sci U S A 105:11915-11920
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11915-11920
-
-
Frank-Kamenetsky, M.1
Grefhorst, A.2
Anderson, N.N.3
Racie, T.S.4
Bramlage, B.5
Akinc, A.6
Butler, D.7
Charisse, K.8
Dorkin, R.9
Fan, Y.10
Gamba-Vitalo, C.11
Hadwiger, P.12
Jayaraman, M.13
John, M.14
Jayaprakash, K.N.15
Maier, M.16
Nechev, L.17
Rajeev, K.G.18
Read, T.19
Rohl, I.20
Soutschek, J.21
Tan, P.22
Wong, J.23
Wang, G.24
Zimmermann, T.25
De Fougerolles, A.26
Vornlocher, H.P.27
Langer, R.28
Anderson, D.G.29
Manoharan, M.30
Koteliansky, V.31
Horton, J.D.32
Fitzgerald, K.33
more..
-
20
-
-
63449135077
-
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma
-
19308264 10.1371/journal.pone.0004998
-
Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, De Martino D, Esposito V, Galeone A, Navas L, Esposito S, Gargiulo S, Fattet S, Donofrio V, Cinalli G, Brunetti A, Vecchio LD, Northcott PA, Delattre O, Taylor MD, Iolascon A, Zollo M (2009) MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PLoS One 4:e4998
-
(2009)
PLoS One
, vol.4
-
-
Garzia, L.1
Andolfo, I.2
Cusanelli, E.3
Marino, N.4
Petrosino, G.5
De Martino, D.6
Esposito, V.7
Galeone, A.8
Navas, L.9
Esposito, S.10
Gargiulo, S.11
Fattet, S.12
Donofrio, V.13
Cinalli, G.14
Brunetti, A.15
Vecchio, L.D.16
Northcott, P.A.17
Delattre, O.18
Taylor, M.D.19
Iolascon, A.20
Zollo, M.21
more..
-
21
-
-
67650711156
-
MicroRNAs in Cancer
-
19630570 10.1146/annurev.med.59.053006.104707 1:CAS:528: DC%2BD1MXitlynt7Y%3D
-
Garzon R, Calin GA, Croce CM (2009) MicroRNAs in Cancer. Annu Rev Med 60:167-179
-
(2009)
Annu Rev Med
, vol.60
, pp. 167-179
-
-
Garzon, R.1
Calin, G.A.2
Croce, C.M.3
-
22
-
-
34047270440
-
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
-
17363563 10.1158/0008-5472.CAN-06-2698 1:CAS:528:DC%2BD2sXivV2gu78%3D
-
Gaur A, Jewell DA, Liang Y, Ridzon D, Moore JH, Chen C, Ambros VR, Israel MA (2007) Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res 67:2456-2468
-
(2007)
Cancer Res
, vol.67
, pp. 2456-2468
-
-
Gaur, A.1
Jewell, D.A.2
Liang, Y.3
Ridzon, D.4
Moore, J.H.5
Chen, C.6
Ambros, V.R.7
Israel, M.A.8
-
23
-
-
84863922166
-
Lipid-based nanoparticles for siRNA delivery in cancer therapy: Paradigms and challenges
-
22568781 10.1021/ar300048p 1:CAS:528:DC%2BC38XmslKis7w%3D
-
Gomes-da-Silva LC, Fonseca NA, Moura V, Pedroso de Lima MC, Simoes S, Moreira JN (2012) Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges. Acc Chem Res 45:1163-1171
-
(2012)
Acc Chem Res
, vol.45
, pp. 1163-1171
-
-
Gomes-Da-Silva, L.C.1
Fonseca, N.A.2
Moura, V.3
Pedroso De Lima, M.C.4
Simoes, S.5
Moreira, J.N.6
-
24
-
-
84861111256
-
The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: The role of the endothelial network
-
22251985 10.1227/01.neu.0000410937.38828.6f
-
Gursel DB, Berry N, Boockvar JA (2012) The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: the role of the endothelial network. Neurosurgery 70:N19-N21
-
(2012)
Neurosurgery
, vol.70
-
-
Gursel, D.B.1
Berry, N.2
Boockvar, J.A.3
-
25
-
-
77954242370
-
Notch signaling is not essential in sonic hedgehog-activated medulloblastoma
-
20440271 10.1038/onc.2010.142 1:CAS:528:DC%2BC3cXlsVyiurc%3D
-
Hatton BA, Villavicencio EH, Pritchard J, LeBlanc M, Hansen S, Ulrich M, Ditzler S, Pullar B, Stroud MR, Olson JM (2010) Notch signaling is not essential in sonic hedgehog-activated medulloblastoma. Oncogene 29:3865-3872
-
(2010)
Oncogene
, vol.29
, pp. 3865-3872
-
-
Hatton, B.A.1
Villavicencio, E.H.2
Pritchard, J.3
Leblanc, M.4
Hansen, S.5
Ulrich, M.6
Ditzler, S.7
Pullar, B.8
Stroud, M.R.9
Olson, J.M.10
-
26
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
17554337 10.1038/nature05939 1:CAS:528:DC%2BD2sXmvFKmu7c%3D
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ (2007) A microRNA component of the p53 tumour suppressor network. Nature 447:1130-1134
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
Jackson, A.L.11
Linsley, P.S.12
Chen, C.13
Lowe, S.W.14
Cleary, M.A.15
Hannon, G.J.16
-
27
-
-
84859309077
-
MicroRNAs and stem cells: Control of pluripotency, reprogramming, and lineage commitment
-
22461365 10.1161/CIRCRESAHA.111.243394 1:CAS:528:DC%2BC38XkvVSru7k%3D
-
Heinrich EM, Dimmeler S (2012) MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitment. Circ Res 110:1014-1022
-
(2012)
Circ Res
, vol.110
, pp. 1014-1022
-
-
Heinrich, E.M.1
Dimmeler, S.2
-
28
-
-
40649083081
-
Biological and genetic characteristics of tumor-initiating cells in colon cancer
-
17932721 10.1245/s10434-007-9605-3
-
Ieta K, Tanaka F, Haraguchi N, Kita Y, Sakashita H, Mimori K, Matsumoto T, Inoue H, Kuwano H, Mori M (2008) Biological and genetic characteristics of tumor-initiating cells in colon cancer. Ann Surg Oncol 15:638-648
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 638-648
-
-
Ieta, K.1
Tanaka, F.2
Haraguchi, N.3
Kita, Y.4
Sakashita, H.5
Mimori, K.6
Matsumoto, T.7
Inoue, H.8
Kuwano, H.9
Mori, M.10
-
29
-
-
39849098719
-
Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling
-
17873912 10.1038/sj.onc.1210767 1:CAS:528:DC%2BD1cXisFWjurc%3D
-
Ingram WJ, McCue KI, Tran TH, Hallahan AR, Wainwright BJ (2008) Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling. Oncogene 27:1489-1500
-
(2008)
Oncogene
, vol.27
, pp. 1489-1500
-
-
Ingram, W.J.1
McCue, K.I.2
Tran, T.H.3
Hallahan, A.R.4
Wainwright, B.J.5
-
30
-
-
27144481028
-
Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy
-
16132349 10.1007/s11095-005-7148-5 1:CAS:528:DC%2BD2MXhtFChs7bI
-
Jores K, Haberland A, Wartewig S, Mader K, Mehnert W (2005) Solid lipid nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and Raman spectroscopy. Pharm Res 22:1887-1897
-
(2005)
Pharm Res
, vol.22
, pp. 1887-1897
-
-
Jores, K.1
Haberland, A.2
Wartewig, S.3
Mader, K.4
Mehnert, W.5
-
31
-
-
32944454941
-
Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo
-
16343994 10.1016/j.ymthe.2005.11.002 1:CAS:528:DC%2BD28XhslyktrY%3D
-
Judge AD, Bola G, Lee AC, MacLachlan I (2006) Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo. Mol Ther 13:494-505
-
(2006)
Mol Ther
, vol.13
, pp. 494-505
-
-
Judge, A.D.1
Bola, G.2
Lee, A.C.3
MacLachlan, I.4
-
32
-
-
65649085603
-
Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice
-
19229107 10.1172/JCI37515 1:CAS:528:DC%2BD1MXivF2ktLc%3D
-
Judge AD, Robbins M, Tavakoli I, Levi J, Hu L, Fronda A, Ambegia E, McClintock K, MacLachlan I (2009) Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice. J Clin Investig 119:661-673
-
(2009)
J Clin Investig
, vol.119
, pp. 661-673
-
-
Judge, A.D.1
Robbins, M.2
Tavakoli, I.3
Levi, J.4
Hu, L.5
Fronda, A.6
Ambegia, E.7
McClintock, K.8
MacLachlan, I.9
-
33
-
-
77953767906
-
Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma
-
20418906 10.1038/onc.2010.101 1:CAS:528:DC%2BC3cXltFKlsbs%3D
-
Julian E, Dave RK, Robson JP, Hallahan AR, Wainwright BJ (2010) Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma. Oncogene 29:3465-3476
-
(2010)
Oncogene
, vol.29
, pp. 3465-3476
-
-
Julian, E.1
Dave, R.K.2
Robson, J.P.3
Hallahan, A.R.4
Wainwright, B.J.5
-
34
-
-
52449116723
-
WNT signaling in stem cell biology and regenerative medicine
-
18673242 10.2174/138945008784911750 1:CAS:528:DC%2BD1cXnsVOqtLY%3D
-
Katoh M (2008) WNT signaling in stem cell biology and regenerative medicine. Curr Drug Targets 9:565-570
-
(2008)
Curr Drug Targets
, vol.9
, pp. 565-570
-
-
Katoh, M.1
-
35
-
-
34748828940
-
Notch signaling in gastrointestinal tract (review)
-
17143535 1:CAS:528:DC%2BD2sXhtFyrurw%3D
-
Katoh M, Katoh M (2007) Notch signaling in gastrointestinal tract (review). Int J Oncol 30:247-251
-
(2007)
Int J Oncol
, vol.30
, pp. 247-251
-
-
Katoh, M.1
Katoh, M.2
-
36
-
-
33344477448
-
Genomics of microRNA
-
16446010 10.1016/j.tig.2006.01.003 1:CAS:528:DC%2BD28XhvVWitLw%3D
-
Kim VN, Nam JW (2006) Genomics of microRNA. Trends Genet 22:165-173
-
(2006)
Trends Genet
, vol.22
, pp. 165-173
-
-
Kim, V.N.1
Nam, J.W.2
-
37
-
-
0034881060
-
Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line
-
11498766 10.1038/sj.cgt.7700326 1:CAS:528:DC%2BD3MXlslKksbY%3D
-
Leonetti C, Biroccio A, Benassi B, Stringaro A, Stoppacciaro A, Semple SC, Zupi G (2001) Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line. Cancer Gene Ther 8:459-468
-
(2001)
Cancer Gene Ther
, vol.8
, pp. 459-468
-
-
Leonetti, C.1
Biroccio, A.2
Benassi, B.3
Stringaro, A.4
Stoppacciaro, A.5
Semple, S.C.6
Zupi, G.7
-
38
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) Method
-
11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) Method. Methods 25:402-408
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
39
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
22439924 10.1016/j.ccr.2012.03.003 1:CAS:528:DC%2BC38Xkt1yltro%3D
-
Magee JA, Piskounova E, Morrison SJ (2012) Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 21(3):283-296
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
40
-
-
84860780308
-
Solid lipid nanoparticles as intracellular drug transporters: An investigation of the uptake mechanism and pathway
-
22465548 10.1016/j.ijpharm.2012.03.032 1:CAS:528:DC%2BC38Xlt1KrsLs%3D
-
Martins S, Costa-Lima S, Carneiro T, Cordeiro-da-Silva A, Souto EB, Ferreira DC (2012) Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway. Int J Pharm 430:216-227
-
(2012)
Int J Pharm
, vol.430
, pp. 216-227
-
-
Martins, S.1
Costa-Lima, S.2
Carneiro, T.3
Cordeiro-Da-Silva, A.4
Souto, E.B.5
Ferreira, D.C.6
-
41
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
15372041 10.1038/nature02873 1:CAS:528:DC%2BD2cXnsFaiu7Y%3D
-
Meister G, Tuschl T (2004) Mechanisms of gene silencing by double-stranded RNA. Nature 431:343-349
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
42
-
-
74549133972
-
Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis
-
20030805 10.1186/1476-4598-8-128
-
Mittal S, Subramanyam D, Dey D, Kumar RV, Rangarajan A (2009) Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis. Mol Cancer 8:128
-
(2009)
Mol Cancer
, vol.8
, pp. 128
-
-
Mittal, S.1
Subramanyam, D.2
Dey, D.3
Kumar, R.V.4
Rangarajan, A.5
-
43
-
-
47149083118
-
Non-viral lipid-based nanoparticles for targeted cancer systemic gene silencing
-
18572631 10.1166/jnn.2008.319 1:CAS:528:DC%2BD1cXmslWrtb8%3D
-
Moreira JN, Santos A, Moura V, Pedroso de Lima MC, Simoes S (2008) Non-viral lipid-based nanoparticles for targeted cancer systemic gene silencing. J Nanosci Nanotechnol 8:2187-2204
-
(2008)
J Nanosci Nanotechnol
, vol.8
, pp. 2187-2204
-
-
Moreira, J.N.1
Santos, A.2
Moura, V.3
Pedroso De Lima, M.C.4
Simoes, S.5
-
44
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
16041363 10.1038/nbt1122 1:CAS:528:DC%2BD2MXntVSrtrc%3D
-
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, Vaish N, Zinnen S, Vargeese C, Bowman K, Shaffer CS, Jeffs LB, Judge A, MacLachlan I, Polisky B (2005) Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat Biotechnol 23:1002-1007
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
Lockridge, J.A.2
Shaw, L.3
Blanchard, K.4
Jensen, K.5
Breen, W.6
Hartsough, K.7
MacHemer, L.8
Radka, S.9
Jadhav, V.10
Vaish, N.11
Zinnen, S.12
Vargeese, C.13
Bowman, K.14
Shaffer, C.S.15
Jeffs, L.B.16
Judge, A.17
MacLachlan, I.18
Polisky, B.19
-
45
-
-
34548241874
-
Shh signaling and pancreatic cancer: Implications for therapy?
-
17611415 10.4161/cc.6.13.4467 1:CAS:528:DC%2BD2sXhtFWlsrzK
-
Morton JP, Lewis BC (2007) Shh signaling and pancreatic cancer: implications for therapy? Cell Cycle 6:1553-1557
-
(2007)
Cell Cycle
, vol.6
, pp. 1553-1557
-
-
Morton, J.P.1
Lewis, B.C.2
-
46
-
-
81855200163
-
Non-coding RNAs in cancer initiation and progression and as novel biomarkers
-
22079056 10.1016/j.molonc.2011.10.003 1:CAS:528:DC%2BC3MXhsFCqsbzK
-
Nana-Sinkam SP, Croce CM (2011) Non-coding RNAs in cancer initiation and progression and as novel biomarkers. Mol Oncol 5:483-491
-
(2011)
Mol Oncol
, vol.5
, pp. 483-491
-
-
Nana-Sinkam, S.P.1
Croce, C.M.2
-
47
-
-
67649295505
-
SiRNA delivery systems for cancer treatment
-
19422869 10.1016/j.addr.2009.04.018 1:CAS:528:DC%2BD1MXnsl2gtbc%3D
-
Oh YK, Park TG (2009) siRNA delivery systems for cancer treatment. Adv Drug Deliv Rev 61:850-862
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 850-862
-
-
Oh, Y.K.1
Park, T.G.2
-
48
-
-
77951690744
-
Lipid-based nanoparticles as pharmaceutical drug carriers: From concepts to clinic
-
20402623 10.1615/CritRevTherDrugCarrierSyst.v26.i6.10 1:CAS:528:DC%2BC3cXntVaks7Y%3D
-
Puri A, Loomis K, Smith B, Lee JH, Yavlovich A, Heldman E, Blumenthal R (2009) Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic. Crit Rev Ther Drug Carrier Syst 26:523-580
-
(2009)
Crit Rev Ther Drug Carrier Syst
, vol.26
, pp. 523-580
-
-
Puri, A.1
Loomis, K.2
Smith, B.3
Lee, J.H.4
Yavlovich, A.5
Heldman, E.6
Blumenthal, R.7
-
49
-
-
58649111264
-
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma
-
19185848 10.1016/j.ccr.2008.12.016 1:CAS:528:DC%2BD1MXltFSmtLY%3D
-
Read TA, Fogarty MP, Markant SL, McLendon RE, Wei Z, Ellison DW, Febbo PG, Wechsler-Reya RJ (2009) Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. Cancer Cell 15:135-147
-
(2009)
Cancer Cell
, vol.15
, pp. 135-147
-
-
Read, T.A.1
Fogarty, M.P.2
Markant, S.L.3
McLendon, R.E.4
Wei, Z.5
Ellison, D.W.6
Febbo, P.G.7
Wechsler-Reya, R.J.8
-
50
-
-
59049088446
-
Activation of Notch signaling in human colon adenocarcinoma
-
19020755
-
Reedijk M, Odorcic S, Zhang H, Chetty R, Tennert C, Dickson BC, Lockwood G, Gallinger S, Egan SE (2008) Activation of Notch signaling in human colon adenocarcinoma. Int J Oncol 33:1223-1229
-
(2008)
Int J Oncol
, vol.33
, pp. 1223-1229
-
-
Reedijk, M.1
Odorcic, S.2
Zhang, H.3
Chetty, R.4
Tennert, C.5
Dickson, B.C.6
Lockwood, G.7
Gallinger, S.8
Egan, S.E.9
-
51
-
-
66249105368
-
SiRNA and innate immunity
-
19441890 10.1089/oli.2009.0180 1:CAS:528:DC%2BD1MXmtFersLc%3D
-
Robbins M, Judge A, MacLachlan I (2009) siRNA and innate immunity. Oligonucleotides 19:89-102
-
(2009)
Oligonucleotides
, vol.19
, pp. 89-102
-
-
Robbins, M.1
Judge, A.2
MacLachlan, I.3
-
53
-
-
78650355900
-
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: A potential mechanism of therapeutic resistance
-
21169257 10.1158/1078-0432.CCR-10-1624 1:CAS:528:DC%2BC3cXhsFOjtr7I
-
Schreck KC, Taylor P, Marchionni L, Gopalakrishnan V, Bar EE, Gaiano N, Eberhart CG (2010) The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance. Clin Cancer Res 16:6060-6070
-
(2010)
Clin Cancer Res
, vol.16
, pp. 6060-6070
-
-
Schreck, K.C.1
Taylor, P.2
Marchionni, L.3
Gopalakrishnan, V.4
Bar, E.E.5
Gaiano, N.6
Eberhart, C.G.7
-
54
-
-
76349111051
-
Rational design of cationic lipids for siRNA delivery
-
20081866 10.1038/nbt.1602 1:CAS:528:DC%2BC3cXntVCqtg%3D%3D
-
Semple SC, Akinc A, Chen J, Sandhu AP, Mui BL, Cho CK, Sah DW, Stebbing D, Crosley EJ, Yaworski E, Hafez IM, Dorkin JR, Qin J, Lam K, Rajeev KG, Wong KF, Jeffs LB, Nechev L, Eisenhardt ML, Jayaraman M, Kazem M, Maier MA, Srinivasulu M, Weinstein MJ, Chen Q, Alvarez R, Barros SA, De S, Klimuk SK, Borland T, Kosovrasti V, Cantley WL, Tam YK, Manoharan M, Ciufolini MA, Tracy MA, de Fougerolles A, MacLachlan I, Cullis PR, Madden TD, Hope MJ (2010) Rational design of cationic lipids for siRNA delivery. Nat Biotechnol 28:172-176
-
(2010)
Nat Biotechnol
, vol.28
, pp. 172-176
-
-
Semple, S.C.1
Akinc, A.2
Chen, J.3
Sandhu, A.P.4
Mui, B.L.5
Cho, C.K.6
Sah, D.W.7
Stebbing, D.8
Crosley, E.J.9
Yaworski, E.10
Hafez, I.M.11
Dorkin, J.R.12
Qin, J.13
Lam, K.14
Rajeev, K.G.15
Wong, K.F.16
Jeffs, L.B.17
Nechev, L.18
Eisenhardt, M.L.19
Jayaraman, M.20
Kazem, M.21
Maier, M.A.22
Srinivasulu, M.23
Weinstein, M.J.24
Chen, Q.25
Alvarez, R.26
Barros, S.A.27
De, S.28
Klimuk, S.K.29
Borland, T.30
Kosovrasti, V.31
Cantley, W.L.32
Tam, Y.K.33
Manoharan, M.34
Ciufolini, M.A.35
Tracy, M.A.36
De Fougerolles, A.37
MacLachlan, I.38
Cullis, P.R.39
Madden, T.D.40
Hope, M.J.41
more..
-
55
-
-
77955970127
-
Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion
-
20799954 10.1186/1476-4598-9-227
-
Shen Q, Cicinnati VR, Zhang X, Iacob S, Weber F, Sotiropoulos GC, Radtke A, Lu M, Paul A, Gerken G, Beckebaum S (2010) Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion. Mol Cancer 9:227
-
(2010)
Mol Cancer
, vol.9
, pp. 227
-
-
Shen, Q.1
Cicinnati, V.R.2
Zhang, X.3
Iacob, S.4
Weber, F.5
Sotiropoulos, G.C.6
Radtke, A.7
Lu, M.8
Paul, A.9
Gerken, G.10
Beckebaum, S.11
-
56
-
-
33751346643
-
CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: An early step necessary for metastasis
-
17062128 10.1186/bcr1610
-
Sheridan C, Kishimoto H, Fuchs RK, Mehrotra S, Bhat-Nakshatri P, Turner CH, Goulet R Jr, Badve S, Nakshatri H (2006) CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res 8:R59
-
(2006)
Breast Cancer Res
, vol.8
, pp. 59
-
-
Sheridan, C.1
Kishimoto, H.2
Fuchs, R.K.3
Mehrotra, S.4
Bhat-Nakshatri, P.5
Turner, C.H.6
Goulet Jr., R.7
Badve, S.8
Nakshatri, H.9
-
57
-
-
57349182470
-
Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells
-
18852283 10.1128/MCB.01962-07 1:CAS:528:DC%2BD1cXhsV2mtLnJ
-
Shimizu T, Kagawa T, Inoue T, Nonaka A, Takada S, Aburatani H, Taga T (2008) Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells. Mol Cell Biol 28:7427-7441
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7427-7441
-
-
Shimizu, T.1
Kagawa, T.2
Inoue, T.3
Nonaka, A.4
Takada, S.5
Aburatani, H.6
Taga, T.7
-
58
-
-
45749102020
-
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors
-
18497886 1:CAS:528:DC%2BD1cXntVCmtLk%3D
-
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S (2008) CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. J Clin Investig 118:2111-2120
-
(2008)
J Clin Investig
, vol.118
, pp. 2111-2120
-
-
Shmelkov, S.V.1
Butler, J.M.2
Hooper, A.T.3
Hormigo, A.4
Kushner, J.5
Milde, T.6
St Clair, R.7
Baljevic, M.8
White, I.9
Jin, D.K.10
Chadburn, A.11
Murphy, A.J.12
Valenzuela, D.M.13
Gale, N.W.14
Thurston, G.15
Yancopoulos, G.D.16
D'Angelica, M.17
Kemeny, N.18
Lyden, D.19
Rafii, S.20
more..
-
59
-
-
23744433700
-
Cationic liposomes for gene delivery
-
16296751 10.1517/17425247.2.2.237 1:CAS:528:DC%2BD2MXjsFantr8%3D
-
Simoes S, Filipe A, Faneca H, Mano M, Penacho N, Duzgunes N, de Lima MP (2005) Cationic liposomes for gene delivery. Expert Opin Drug Deliv 2:237-254
-
(2005)
Expert Opin Drug Deliv
, vol.2
, pp. 237-254
-
-
Simoes, S.1
Filipe, A.2
Faneca, H.3
Mano, M.4
Penacho, N.5
Duzgunes, N.6
De Lima, M.P.7
-
60
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
15549107 10.1038/nature03128 1:CAS:528:DC%2BD2cXpvVCjtbY%3D
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB (2004) Identification of human brain tumour initiating cells. Nature 432:396-401
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
61
-
-
84863194833
-
Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect
-
22411910 10.1093/nar/gks204 1:CAS:528:DC%2BC38XpsFKmsbg%3D
-
Takahashi M, Nagai C, Hatakeyama H, Minakawa N, Harashima H, Matsuda A (2012) Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect. Nucleic Acids Res 40:5787-5793
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5787-5793
-
-
Takahashi, M.1
Nagai, C.2
Hatakeyama, H.3
Minakawa, N.4
Harashima, H.5
Matsuda, A.6
-
62
-
-
76549122768
-
The many roles of microRNAs in brain tumor biology
-
Turner JD, Williamson R, Almefty KK, Nakaji P, Porter R, Tse V, Kalani MY (2010) The many roles of microRNAs in brain tumor biology. Neurosurg Focus 28: E3
-
(2010)
Neurosurg Focus
, vol.28
-
-
Turner, J.D.1
Williamson, R.2
Almefty, K.K.3
Nakaji, P.4
Porter, R.5
Tse, V.6
Kalani, M.Y.7
-
63
-
-
80054959463
-
Underexpressed microRNA-199b-5p targets hypoxia-inducible factor-1alpha in hepatocellular carcinoma and predicts prognosis of hepatocellular carcinoma patients
-
21557766 10.1111/j.1440-1746.2011.06758.x 1:CAS:528:DC%2BC3MXhsFyks77K
-
Wang C, Song B, Song W, Liu J, Sun A, Wu D, Yu H, Lian J, Chen L, Han J (2011) Underexpressed microRNA-199b-5p targets hypoxia-inducible factor-1alpha in hepatocellular carcinoma and predicts prognosis of hepatocellular carcinoma patients. J Gastroenterol Hepatol 26:1630-1637
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 1630-1637
-
-
Wang, C.1
Song, B.2
Song, W.3
Liu, J.4
Sun, A.5
Wu, D.6
Yu, H.7
Lian, J.8
Chen, L.9
Han, J.10
-
64
-
-
70449378959
-
Proteomics for brain disorders - The promise for biomarkers
-
19906262 10.1111/j.1749-6632.2009.05018.x
-
Ward M, Guntert A, Campbell J, Pike I (2009) Proteomics for brain disorders - the promise for biomarkers. Ann N Y Acad Sci 1180:68-74
-
(2009)
Ann N y Acad Sci
, vol.1180
, pp. 68-74
-
-
Ward, M.1
Guntert, A.2
Campbell, J.3
Pike, I.4
-
65
-
-
52049090811
-
Chemically modified siRNA: Tools and applications
-
18614389 10.1016/j.drudis.2008.05.007 1:CAS:528:DC%2BD1cXhtFCgu7bF
-
Watts JK, Deleavey GF, Damha MJ (2008) Chemically modified siRNA: tools and applications. Drug Discov Today 13:842-855
-
(2008)
Drug Discov Today
, vol.13
, pp. 842-855
-
-
Watts, J.K.1
Deleavey, G.F.2
Damha, M.J.3
-
66
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
19180106 10.1038/nrd2742 1:CAS:528:DC%2BD1MXhtFOqt70%3D
-
Whitehead KA, Langer R, Anderson DG (2009) Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov 8:129-138
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
-
67
-
-
0037382649
-
Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors
-
12666205 10.1002/dvdy.10278 1:CAS:528:DC%2BD3sXjtFOitbo%3D
-
Wu Y, Liu Y, Levine EM, Rao MS (2003) Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors. Dev Dyn 226:675-689
-
(2003)
Dev Dyn
, vol.226
, pp. 675-689
-
-
Wu, Y.1
Liu, Y.2
Levine, E.M.3
Rao, M.S.4
-
68
-
-
81255157791
-
Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy
-
21839126 10.1016/j.jconrel.2011.07.035 1:CAS:528:DC%2BC3MXhsVyltLfJ
-
Yang XZ, Dou S, Sun TM, Mao CQ, Wang HX, Wang J (2011) Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy. J Control Release 156:203-211
-
(2011)
J Control Release
, vol.156
, pp. 203-211
-
-
Yang, X.Z.1
Dou, S.2
Sun, T.M.3
Mao, C.Q.4
Wang, H.X.5
Wang, J.6
-
69
-
-
33846188098
-
MicroRNAs as oncogenes and tumor suppressors
-
16989803 10.1016/j.ydbio.2006.08.028 1:CAS:528:DC%2BD2sXntlOnuw%3D%3D
-
Zhang B, Pan X, Cobb GP, Anderson TA (2007) microRNAs as oncogenes and tumor suppressors. Dev Biol 302:1-12
-
(2007)
Dev Biol
, vol.302
, pp. 1-12
-
-
Zhang, B.1
Pan, X.2
Cobb, G.P.3
Anderson, T.A.4
-
70
-
-
80455123713
-
New role of microRNA: Carcinogenesis and clinical application in cancer
-
10.1093/abbs/gmr080 1:CAS:528:DC%2BC3MXhtlyqtLbI
-
Zhao L, Chen X, Cao Y (2011) New role of microRNA: carcinogenesis and clinical application in cancer. Acta Biochim Biophys Sin (Shanghai) 43:831-839
-
(2011)
Acta Biochim Biophys Sin (Shanghai)
, vol.43
, pp. 831-839
-
-
Zhao, L.1
Chen, X.2
Cao, Y.3
-
71
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
16565705 10.1038/nature04688 1:CAS:528:DC%2BD28XktVGlt7w%3D
-
Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN, Harborth J, Heyes JA, Jeffs LB, John M, Judge AD, Lam K, McClintock K, Nechev LV, Palmer LR, Racie T, Rohl I, Seiffert S, Shanmugam S, Sood V, Soutschek J, Toudjarska I, Wheat AJ, Yaworski E, Zedalis W, Koteliansky V, Manoharan M, Vornlocher HP, MacLachlan I (2006) RNAi-mediated gene silencing in non-human primates. Nature 441:111-114
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmermann, T.S.1
Lee, A.C.2
Akinc, A.3
Bramlage, B.4
Bumcrot, D.5
Fedoruk, M.N.6
Harborth, J.7
Heyes, J.A.8
Jeffs, L.B.9
John, M.10
Judge, A.D.11
Lam, K.12
McClintock, K.13
Nechev, L.V.14
Palmer, L.R.15
Racie, T.16
Rohl, I.17
Seiffert, S.18
Shanmugam, S.19
Sood, V.20
Soutschek, J.21
Toudjarska, I.22
Wheat, A.J.23
Yaworski, E.24
Zedalis, W.25
Koteliansky, V.26
Manoharan, M.27
Vornlocher, H.P.28
MacLachlan, I.29
more..
|