Protection of Cells against Oxidative Stress by Nanomolar Levels of Hydroxyflavones Indicates a New Type of Intracellular Antioxidant Mechanism

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Lombardo, Emanuele ^a   Sabellico, Cristian ^a   Hájek, Jan ^b,e   Staňková, Veronika ^b,e   Filipský, Tomáš ^b,e   Balducci, Valentina ^a   De Vito, Paolo ^c   Leone, Stefano ^a   Bavavea, Eugenia I ^d,e   Silvestri, Ilaria Proietti ^e   Righi, Giuliana ^f   Luly, Paolo ^c   Saso, Luciano ^e   Bovicelli, Paolo ^f   Pedersen, Jens Z ^c   Incerpi, Sandra ^a  

^a ROMA TRE UNIVERSITY   (Italy)

^b Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d UNIVERSITY OF ATHENS   (Greece)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIHYDROXYFLAVONE; BAICALEIN; CUMENE HYDROPEROXIDE; FLAVONE DERIVATIVE; MOSLOFLAVONE; NEGLETEIN; QUERCETIN; SCAVENGER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOLECULAR PROBE; MONOCYTE; MYOBLAST; NONHUMAN; OXIDATIVE STRESS; RAT; STOICHIOMETRY;

ANIMALS; ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVANONES; FLAVONES; FREE RADICAL SCAVENGERS; HUMANS; MONOCYTES; MYOBLASTS; OXIDATIVE STRESS; RATS;

EID: 84876321750     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060796     Document Type: Article

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