Inhibition of 12-LOX and COX-2 reduces the proliferation of human epidermoid carcinoma cells (A431) by modulating the ERK and PI3K-Akt signalling pathways

Experimental Dermatology

Volumn 18, Issue 11, 2009, Pages 939-946

  Agarwal, Smita ^a   Achari, Chandrani ^a   Praveen, D ^a   Roy, Karnati R ^a   Reddy, Gorla Venkateswara ^a   Reddanna, Pallu ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

12 R LOX; Akt; Apoptosis; COX 2; ERK

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; BAICALEIN; CELECOXIB; CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIPOXYGENASE; MEMBRANE POTENTIALS; MICE; NIH 3T3 CELLS;

EID: 70350770922     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2009.00874.x     Document Type: Article

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