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Volumn 1, Issue 2, 2012, Pages 180-186

Catalytic Asymmetric Synthesis of 3-Substituted Proline Derivatives by Using Phase-Transfer-Catalyzed Conjugate Addition

Author keywords

Asymmetric synthesis; Conjugate addition; Organocatalysis; Phase transfer catalysis; Synthetic methods

Indexed keywords


EID: 84876245423     PISSN: 21935807     EISSN: 21935807     Source Type: Journal    
DOI: 10.1002/ajoc.201200039     Document Type: Article
Times cited : (16)

References (100)
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    • For recent reviews on asymmetric phase-transfer catalysis
    • For recent reviews on asymmetric phase-transfer catalysis, see:
  • 52
    • 84899791469 scopus 로고    scopus 로고
    • Asymmetric synthesis of cyclic amino acids based on the phase-transfer-catalyzed conjugate additions
    • Asymmetric synthesis of cyclic amino acids based on the phase-transfer-catalyzed conjugate additions, see:
  • 58
    • 84899875268 scopus 로고    scopus 로고
    • For representative examples of asymmetric conjugate addition of glycine ester under phase-transfer conditions,
    • For representative examples of asymmetric conjugate addition of glycine ester under phase-transfer conditions, see:
  • 75
    • 84899816531 scopus 로고    scopus 로고
    • CCDC877856 contains the supplementary crystallographic data for 1f'. These data can be obtained free of charge from the Cambridge Crystallographic Data Centre via
    • CCDC877856 contains the supplementary crystallographic data for 1f'. These data can be obtained free of charge from the Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif.
  • 80
    • 84899885497 scopus 로고    scopus 로고
    • The major diastereomer of 3i was selectively cyclized in the isolation step, and 4i was obtained as a single diastereomer.
    • The major diastereomer of 3i was selectively cyclized in the isolation step, and 4i was obtained as a single diastereomer.
  • 89
    • 84899827868 scopus 로고    scopus 로고
    • WO 2008090819
    • T. Hamada, WO 2008090819, 2008.
    • (2008)
    • Hamada, T.1
  • 94
    • 84899836663 scopus 로고    scopus 로고
    • When catalyst (S,S)-9c was applied to the reaction in Scheme4, the product 4i was obtained in 68% yield, 50% ee.
    • When catalyst (S, S)-9c was applied to the reaction in Scheme4, the product 4i was obtained in 68% yield, -50% ee.
  • 95
    • 84899812849 scopus 로고    scopus 로고
    • 2H. These data can be obtained free of charge from the Cambridge Crystallographic Data Centre via
    • 2H. These data can be obtained free of charge from the Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif.
  • 100
    • 84899796751 scopus 로고    scopus 로고
    • After the reaction, catalyst (S,S)-9c could be recovered (ca.80%) by column chromatography and reused without loss of activity.
    • After the reaction, catalyst (S, S)-9c could be recovered (ca.80%) by column chromatography and reused without loss of activity.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.