Fine-tuning of voltage sensitivity of the Kv1.2 potassium channel by interhelix loop dynamics

Journal of Biological Chemistry

Volumn 288, Issue 14, 2013, Pages 9686-9695

  Sand, Rheanna ^a   Sharmin, Nazlee ^a   Morgan, Carla ^a   Gallin, Warren J ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COVALENT INTERACTIONS; FUNCTIONAL CONFORMATIONS; MOLECULAR DYNAMICS SIMULATIONS; NON-COVALENT INTERACTION; TRANSMEMBRANE HELICES; TRANSMEMBRANE VOLTAGE; VOLTAGE GATED ION CHANNELS; VOLTAGE-GATED POTASSIUM CHANNELS;

BIOLOGICAL MEMBRANES; CONFORMATIONS; MOLECULAR DYNAMICS;

PROTEINS;

POTASSIUM CHANNEL KV1.2;

ANIMAL CELL; ARTICLE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTRIC POTENTIAL; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; RAT; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; ELECTROPHYSIOLOGY; KV1.2 POTASSIUM CHANNEL; MICE; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; POTASSIUM CHANNELS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SURFACE PROPERTIES; THERMODYNAMICS; XENOPUS LAEVIS;

RATTUS;

EID: 84875983028     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.437483     Document Type: Article

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