-
1
-
-
0030175348
-
Contribution of the S4 segment to gating charge in the Shaker K+ channel
-
Aggarwal, S.K., and R. MacKinnon. 1996. Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron. 16: 1169-1177. http://dx.doi.org/10.1016/S0896-6273(00)80143-9
-
(1996)
Neuron
, vol.16
, pp. 1169-1177
-
-
Aggarwal, S.K.1
MacKinnon, R.2
-
2
-
-
0019596088
-
Sodium channels and gating currents
-
Armstrong, C.M. 1981. Sodium channels and gating currents. Physiol. Rev. 61:644-683.
-
(1981)
Physiol. Rev.
, vol.61
, pp. 644-683
-
-
Armstrong, C.M.1
-
3
-
-
0037426919
-
A fluorometric approach to local electric field measurements in a voltage-gated ion channel
-
Asamoah, O.K., J.P. Wuskell, L.M. Loew, and F. Bezanilla. 2003. A fluorometric approach to local electric field measurements in a voltage-gated ion channel. Neuron. 37:85-97.
-
(2003)
Neuron
, vol.37
, pp. 85-97
-
-
Asamoah, O.K.1
Wuskell, J.P.2
Loew, L.M.3
Bezanilla, F.4
-
4
-
-
0029800696
-
Two functionally distinct subsites for the binding of internal blockers to the pore of voltageactivated K+ channels
-
Baukrowitz, T., and G. Yellen. 1996a. Two functionally distinct subsites for the binding of internal blockers to the pore of voltageactivated K+ channels. Proc. Natl. Acad. Sci. USA. 93:13357-13361. http://dx.doi.org/10.1073/pnas.93.23.13357
-
(1996)
Proc. Natl. Acad. Sci. USA.
, vol.93
, pp. 13357-13361
-
-
Baukrowitz, T.1
Yellen, G.2
-
5
-
-
0030031856
-
Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a K+ channel
-
Baukrowitz, T., and G. Yellen. 1996b. Use-dependent blockers and exit rate of the last ion from the multi-ion pore of a K+ channel. Science. 271:653-656. http://dx.doi.org/10.1126/science.271 .5249.653
-
(1996)
Science
, vol.271
, pp. 653-656
-
-
Baukrowitz, T.1
Yellen, G.2
-
6
-
-
0028213205
-
Gating of Shaker K+ channels: II The components of gating currents and a model of channel activation
-
Bezanilla, F., E. Perozo, and E. Stefani. 1994. Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation. Biophys. J. 66:1011-1021. http://dx.doi.org/ 10.1016/S0006-3495(94)80882-3
-
(1994)
Biophys. J.
, vol.66
, pp. 1011-1021
-
-
Bezanilla, F.1
Perozo, E.2
Stefani, E.3
-
7
-
-
0024311951
-
Comparison of the high-resolution structures of the alpha-amylase inhibitor tendamistat determined by nuclear magnetic resonance in solution and by X-ray diffraction in single crystals
-
Billeter, M., A.D. Kline, W. Braun, R. Huber, and K. Wüthrich. 1989. Comparison of the high-resolution structures of the alpha-amylase inhibitor tendamistat determined by nuclear magnetic resonance in solution and by X-ray diffraction in single crystals. J. Mol. Biol. 206:677-687. http://dx.doi.org/10.1016/0022-2836(89)90575-5
-
(1989)
J. Mol. Biol.
, vol.206
, pp. 677-687
-
-
Billeter, M.1
Kline, A.D.2
Braun, W.3
Huber, R.4
Wüthrich, K.5
-
8
-
-
61449172924
-
Conformational changes and slow dynamics through microsecond polarized atomistic molecular simulation of an integral Kv1 2 ion channel
-
Bjelkmar, P., P.S. Niemelä, I. Vattulainen, and E. Lindahl. 2009. Conformational changes and slow dynamics through microsecond polarized atomistic molecular simulation of an integral Kv1.2 ion channel. PLOS Comput. Biol. 5:e1000289. http://dx.doi .org/10.1371/journal.pcbi.1000289
-
(2009)
PLOS Comput. Biol.
, vol.5
-
-
Bjelkmar, P.1
Niemelä, P.S.2
Vattulainen, I.3
Lindahl, E.4
-
9
-
-
84861965030
-
Improving the accuracy of macromolecular structure refinement at 7 Å resolution
-
Brunger, A.T., P.D. Adams, P. Fromme, R. Fromme, M. Levitt, and G.F. Schröder. 2012. Improving the accuracy of macromolecular structure refinement at 7 Å resolution. Structure. 20:957-966. http://dx.doi.org/10.1016/j.str.2012.04.020
-
(2012)
Structure
, vol.20
, pp. 957-966
-
-
Brunger, A.T.1
Adams, P.D.2
Fromme, P.3
Fromme, R.4
Levitt, M.5
Schröder, G.F.6
-
10
-
-
34249946312
-
Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel
-
Campos, F.V., B. Chanda, B. Roux, and F. Bezanilla. 2007. Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel. Proc. Natl. Acad. Sci. USA. 104:7904-7909. http://dx.doi.org/ 10.1073/pnas.0702638104
-
(2007)
Proc. Natl. Acad. Sci. USA.
, vol.104
, pp. 7904-7909
-
-
Campos, F.V.1
Chanda, B.2
Roux, B.3
Bezanilla, F.4
-
11
-
-
0022555877
-
Molecular properties of voltage-sensitive sodium channels
-
Catterall, W.A. 1986a. Molecular properties of voltage-sensitive sodium channels. Annu. Rev. Biochem. 55:953-985. http://dx.doi .org/10.1146/annurev.bi.55.070186.004513
-
(1986)
Annu. Rev. Biochem.
, vol.55
, pp. 953-985
-
-
Catterall, W.A.1
-
12
-
-
0022658001
-
Voltage-dependent gating of sodium channels: correlating structure and function
-
Catterall, W.A. 1986b. Voltage-dependent gating of sodium channels: correlating structure and function. Trends Neurosci. 9:7-10. http://dx.doi.org/10.1016/0166-2236(86)90004-4
-
(1986)
Trends Neurosci
, vol.9
, pp. 7-10
-
-
Catterall, W.A.1
-
13
-
-
84861716984
-
Voltage-gated sodium channels at 60 structure, function and pathophysiology
-
Catterall, W.A. 2012. Voltage-gated sodium channels at 60: structure, function and pathophysiology. J. Physiol. 590:2577-2589. http://dx.doi.org/10.1113/jphysiol.2011.224204
-
(2012)
J. Physiol.
, vol.590
, pp. 2577-2589
-
-
Catterall, W.A.1
-
14
-
-
23844459909
-
Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement
-
Chanda, B., O.K. Asamoah, R. Blunck, B. Roux, and F. Bezanilla. 2005. Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement. Nature. 436:852-856. http://dx.doi.org/10.1038/nature03888
-
(2005)
Nature
, vol.436
, pp. 852-856
-
-
Chanda, B.1
Asamoah, O.K.2
Blunck, R.3
Roux, B.4
Bezanilla, F.5
-
15
-
-
34547762177
-
Normalmode refinement of anisotropic thermal parameters for potassium channel KcsA at 3 2 A crystallographic resolution
-
Chen, X., B.K. Poon, A. Dousis, Q. Wang, and J. Ma. 2007. Normalmode refinement of anisotropic thermal parameters for potassium channel KcsA at 3.2 A crystallographic resolution. Structure. 15:955-962. http://dx.doi.org/10.1016/j.str.2007.06.012
-
(2007)
Structure
, vol.15
, pp. 955-962
-
-
Chen, X.1
Poon, B.K.2
Dousis, A.3
Wang, Q.4
Ma, J.5
-
16
-
-
40349085541
-
Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel
-
Clayton, G.M., S. Altieri, L. Heginbotham, V.M. Unger, and J.H. Morais-Cabral. 2008. Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel. Proc. Natl. Acad. Sci. USA. 105:1511-1515. http://dx.doi.org/10.1073/pnas .0711533105
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 1511-1515
-
-
Clayton, G.M.1
Altieri, S.2
Heginbotham, L.3
Unger, V.M.4
Morais-Cabral, J.H.5
-
17
-
-
0002415827
-
Potassium ion current in the squid giant axon: dynamic characteristic
-
Cole, K.S., and J.W. Moore. 1960. Potassium ion current in the squid giant axon: dynamic characteristic. Biophys. J. 1:1-14. http://dx .doi.org/10.1016/S0006-3495(60)86871-3
-
(1960)
Biophys. J.
, vol.1
, pp. 1-14
-
-
Cole, K.S.1
Moore, J.W.2
-
18
-
-
54449100445
-
Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation
-
DeCaen, P.G., V. Yarov-Yarovoy, Y. Zhao, T. Scheuer, and W.A. Catterall. 2008. Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation. Proc. Natl. Acad. Sci. USA. 105:15142-15147. http://dx.doi.org/10.1073/pnas .0806486105
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 15142-15147
-
-
DeCaen, P.G.1
Yarov-Yarovoy, V.2
Zhao, Y.3
Scheuer, T.4
Catterall, W.A.5
-
19
-
-
76049115811
-
Sequential formation of ion pairs during activation of a sodium channel voltage sensor
-
DeCaen, P.G., V. Yarov-Yarovoy, E.M. Sharp, T. Scheuer, and W.A. Catterall. 2009. Sequential formation of ion pairs during activation of a sodium channel voltage sensor. Proc. Natl. Acad. Sci. USA. 106:22498-22503. http://dx.doi.org/10.1073/pnas.0912307106
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 22498-22503
-
-
DeCaen, P.G.1
Yarov-Yarovoy, V.2
Sharp, E.M.3
Scheuer, T.4
Catterall, W.A.5
-
20
-
-
81755185839
-
Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor
-
DeCaen, P.G., V. Yarov-Yarovoy, T. Scheuer, and W.A. Catterall. 2011. Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor. Proc. Natl. Acad. Sci. USA. 108:18825-18830. http://dx.doi.org/10.1073/pnas.1116449108
-
(2011)
Proc. Natl. Acad. Sci. USA.
, vol.108
, pp. 18825-18830
-
-
DeCaen, P.G.1
Yarov-Yarovoy, V.2
Scheuer, T.3
Catterall, W.A.4
-
21
-
-
78349287755
-
Effect of sensor domain mutations on the properties of voltage-gated ion channels: molecular dynamics studies of the potassium channel Kv1
-
Delemotte, L., W. Treptow, M.L. Klein, and M. Tarek. 2010. Effect of sensor domain mutations on the properties of voltage-gated ion channels: molecular dynamics studies of the potassium channel Kv1.2. Biophys. J. 99:L72-L74. http://dx.doi.org/10.1016/j .bpj.2010.08.069
-
(2010)
2. Biophys. J.
, vol.99
-
-
Delemotte, L.1
Treptow, W.2
Klein, M.L.3
Tarek, M.4
-
22
-
-
79954991393
-
Intermediate states of the Kv1 2 voltage sensor from atomistic molecular dynamics simulations
-
Delemotte, L., M. Tarek, M.L. Klein, C. Amaral, and W. Treptow. 2011. Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations. Proc. Natl. Acad. Sci. USA. 108:6109-6114. http://dx.doi.org/10.1073/pnas.1102724108
-
(2011)
Proc. Natl. Acad. Sci. USA.
, vol.108
, pp. 6109-6114
-
-
Delemotte, L.1
Tarek, M.2
Klein, M.L.3
Amaral, C.4
Treptow, W.5
-
23
-
-
84866023433
-
Molecular dynamics simulations of voltage-gated cation channels: insights on voltagesensor domain function and modulation
-
Delemotte, L., M.L. Klein, and M. Tarek. 2012. Molecular dynamics simulations of voltage-gated cation channels: insights on voltagesensor domain function and modulation. Front Pharmacol. 3:97. http://dx.doi.org/10.3389/fphar.2012.00097
-
(2012)
Front Pharmacol
, vol.3
, pp. 97
-
-
Delemotte, L.1
Klein, M.L.2
Tarek, M.3
-
24
-
-
70350787095
-
From the gating charge response to pore domain movement: initial motions of Kv1 2 dynamics under physiological voltage changes
-
Denning, E.J., P.S. Crozier, J.N. Sachs, and T.B. Woolf. 2009. From the gating charge response to pore domain movement: initial motions of Kv1.2 dynamics under physiological voltage changes. Mol. Membr. Biol. 26:397-421. http://dx.doi.org/10 .3109/09687680903278539
-
(2009)
Mol. Membr. Biol.
, vol.26
, pp. 397-421
-
-
Denning, E.J.1
Crozier, P.S.2
Sachs, J.N.3
Woolf, T.B.4
-
25
-
-
79957592606
-
Improved molecular replacement by density- and energy-guided protein structure optimization
-
DiMaio, F., T.C. Terwilliger, R.J. Read, A. Wlodawer, G. Oberdorfer, U. Wagner, E. Valkov, A. Alon, D. Fass, H.L. Axelrod, et al. 2011. Improved molecular replacement by density- and energy-guided protein structure optimization. Nature. 473:540-543. http://dx .doi.org/10.1038/nature09964
-
(2011)
Nature
, vol.473
, pp. 540-543
-
-
DiMaio, F.1
Terwilliger, T.C.2
Read, R.J.3
Wlodawer, A.4
Oberdorfer, G.5
Wagner, U.6
Valkov, E.7
Alon, A.8
Fass, D.9
Axelrod, H.L.10
-
26
-
-
84861845192
-
Microscopic origin of gating current fluctuations in a potassium channel voltage sensor
-
Freites, J.A., E.V. Schow, S.H. White, and D.J. Tobias. 2012. Microscopic origin of gating current fluctuations in a potassium channel voltage sensor. Biophys. J. 102:L44-L46. http://dx.doi.org/ 10.1016/j.bpj.2012.04.021
-
(2012)
Biophys. J.
, vol.102
-
-
Freites, J.A.1
Schow, E.V.2
White, S.H.3
Tobias, D.J.4
-
27
-
-
0000882125
-
Molecular model of the action potential sodium channel
-
Guy, H.R., and P. Seetharamulu. 1986. Molecular model of the action potential sodium channel. Proc. Natl. Acad. Sci. USA. 83:508-512. http://dx.doi.org/10.1073/pnas.83.2.508
-
(1986)
Proc. Natl. Acad. Sci. USA.
, vol.83
, pp. 508-512
-
-
Guy, H.R.1
Seetharamulu, P.2
-
28
-
-
84861838905
-
Tracking a complete voltage-sensor cycle with metal-ion bridges
-
Henrion, U., J. Renhorn, S.I. Börjesson, E.M. Nelson, C.S. Schwaiger, P. Bjelkmar, B. Wallner, E. Lindahl, and F. Elinder. 2012. Tracking a complete voltage-sensor cycle with metal-ion bridges. Proc. Natl. Acad. Sci. USA. 109:8552-8557. http://dx.doi.org/10.1073/pnas .1116938109
-
(2012)
Proc. Natl. Acad. Sci. USA.
, vol.109
, pp. 8552-8557
-
-
Henrion, U.1
Renhorn, J.2
Börjesson, S.I.3
Nelson, E.M.4
Schwaiger, C.S.5
Bjelkmar, P.6
Wallner, B.7
Lindahl, E.8
Elinder, F.9
-
29
-
-
0035170817
-
Electrostatics and the gating pore of Shaker potassium channels
-
Islas, L.D., and F.J. Sigworth. 2001. Electrostatics and the gating pore of Shaker potassium channels. J. Gen. Physiol. 117:69-89. http:// dx.doi.org/10.1085/jgp.117.1.69
-
(2001)
J. Gen. Physiol.
, vol.117
, pp. 69-89
-
-
Islas, L.D.1
Sigworth, F.J.2
-
30
-
-
77950544751
-
Principles of conduction and hydrophobic gating in K+ channels
-
Jensen, M.O., D.W. Borhani, K. Lindorff-Larsen, P. Maragakis, V. Jogini, M.P. Eastwood, R.O. Dror, and D.E. Shaw. 2010. Principles of conduction and hydrophobic gating in K+ channels. Proc. Natl. Acad. Sci. USA. 107:5833-5838. http://dx.doi.org/10.1073/ pnas.0911691107
-
(2010)
Proc. Natl. Acad. Sci. USA.
, vol.107
, pp. 5833-5838
-
-
Jensen, M.O.1
Borhani, D.W.2
Lindorff-Larsen, K.3
Maragakis, P.4
Jogini, V.5
Eastwood, M.P.6
Dror, R.O.7
Shaw, D.E.8
-
31
-
-
84859651420
-
Mechanism of voltage gating in potassium channels
-
Jensen, M.O., V. Jogini, D.W. Borhani, A.E. Leffler, R.O. Dror, and D.E. Shaw. 2012. Mechanism of voltage gating in potassium channels. Science. 336:229-233. http://dx.doi.org/10.1126/science .1216533
-
(2012)
Science
, vol.336
, pp. 229-233
-
-
Jensen, M.O.1
Jogini, V.2
Borhani, D.W.3
Leffler, A.E.4
Dror, R.O.5
Shaw, D.E.6
-
32
-
-
0038752614
-
The principle of gating charge movement in a voltage-dependent K+ channel
-
Jiang, Y., V. Ruta, J. Chen, A. Lee, and R. MacKinnon. 2003. The principle of gating charge movement in a voltage-dependent K+ channel. Nature. 423:42-48. http://dx.doi.org/10.1038/nature01581
-
(2003)
Nature
, vol.423
, pp. 42-48
-
-
Jiang, Y.1
Ruta, V.2
Chen, J.3
Lee, A.4
MacKinnon, R.5
-
33
-
-
77952700991
-
Calculation of the gating charge for the Kv1 2 voltage-activated potassium channel
-
Khalili-Araghi, F., V. Jogini, V. Yarov-Yarovoy, E. Tajkhorshid, B. Roux, and K. Schulten. 2010. Calculation of the gating charge for the Kv1.2 voltage-activated potassium channel. Biophys. J. 98:2189-2198. http://dx.doi.org/10.1016/j.bpj.2010.02.056
-
(2010)
Biophys. J.
, vol.98
, pp. 2189-2198
-
-
Khalili-Araghi, F.1
Jogini, V.2
Yarov-Yarovoy, V.3
Tajkhorshid, E.4
Roux, B.5
Schulten, K.6
-
34
-
-
84855997898
-
Molecular dynamics investigation of the w-current in the Kv1 2 voltage sensor domains
-
Khalili-Araghi, F., E. Tajkhorshid, B. Roux, and K. Schulten. 2012. Molecular dynamics investigation of the ω-current in the Kv1.2 voltage sensor domains. Biophys. J. 102:258-267. http://dx.doi .org/10.1016/j.bpj.2011.10.057
-
(2012)
Biophys. J.
, vol.102
, pp. 258-267
-
-
Khalili-Araghi, F.1
Tajkhorshid, E.2
Roux, B.3
Schulten, K.4
-
35
-
-
79953872161
-
Properties of deactivation gating currents in Shaker channels
-
Lacroix, J.J., A.J. Labro, and F. Bezanilla. 2011. Properties of deactivation gating currents in Shaker channels. Biophys. J. 100:L28- L30. http://dx.doi.org/10.1016/j.bpj.2011.01.043
-
(2011)
Biophys. J.
, vol.100
-
-
Lacroix, J.J.1
Labro, A.J.2
Bezanilla, F.3
-
36
-
-
84871029215
-
Intermediate state trapping of a voltage sensor
-
Lacroix, J.J., S.A. Pless, L. Maragliano, F.V. Campos, J.D. Jason, D. Galpin, C.A. Ahern, B. Roux, and F. Bezanilla. 2012. Intermediate state trapping of a voltage sensor. J. Gen. Physiol. 140:635-652.
-
(2012)
J. Gen. Physiol.
, vol.140
, pp. 635-652
-
-
Lacroix, J.J.1
Pless, S.A.2
Maragliano, L.3
Campos, F.V.4
Jason, J.D.5
Galpin, D.6
Ahern, C.A.7
Roux, B.8
Bezanilla, F.9
-
37
-
-
84863570589
-
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
-
Lange, O.F., P. Rossi, N.G. Sgourakis, Y. Song, H.W. Lee, J.M. Aramini, A. Ertekin, R. Xiao, T.B. Acton, G.T. Montelione, and D. Baker. 2012. Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc. Natl. Acad. Sci. USA. 109:10873-10878. http:// dx.doi.org/10.1073/pnas.1203013109
-
(2012)
Proc. Natl. Acad. Sci. USA.
, vol.109
, pp. 10873-10878
-
-
Lange, O.F.1
Rossi, P.2
Sgourakis, N.G.3
Song, Y.4
Lee, H.W.5
Aramini, J.M.6
Ertekin, A.7
Xiao, R.8
Acton, T.B.9
Montelione, G.T.10
Baker, D.11
-
38
-
-
23244441222
-
Voltage sensor of Kv1 2: structural basis of electromechanical coupling
-
Long, S.B., E.B. Campbell, and R. Mackinnon. 2005. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science. 309:903-908. http://dx.doi.org/10.1126/science.1116270
-
(2005)
Science
, vol.309
, pp. 903-908
-
-
Long, S.B.1
Campbell, E.B.2
Mackinnon, R.3
-
39
-
-
36248982122
-
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
-
Long, S.B., X. Tao, E.B. Campbell, and R. MacKinnon. 2007. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature. 450:376-382. http://dx.doi .org/10.1038/nature06265
-
(2007)
Nature
, vol.450
, pp. 376-382
-
-
Long, S.B.1
Tao, X.2
Campbell, E.B.3
MacKinnon, R.4
-
40
-
-
50349088433
-
Molecular dynamics simulation of Kv channel voltage sensor helix in a lipid membrane with applied electric field
-
Nishizawa, M., and K. Nishizawa. 2008. Molecular dynamics simulation of Kv channel voltage sensor helix in a lipid membrane with applied electric field. Biophys. J. 95:1729-1744. http://dx.doi .org/10.1529/biophysj.108.130658
-
(2008)
Biophys. J.
, vol.95
, pp. 1729-1744
-
-
Nishizawa, M.1
Nishizawa, K.2
-
41
-
-
68949118408
-
Coupling of S4 helix translocation and S6 gating analyzed by molecular-dynamics simulations of mutated Kv channels
-
Nishizawa, M., and K. Nishizawa. 2009. Coupling of S4 helix translocation and S6 gating analyzed by molecular-dynamics simulations of mutated Kv channels. Biophys. J. 97:90-100. http://dx.doi.org/ 10.1016/j.bpj.2009.02.074
-
(2009)
Biophys. J.
, vol.97
, pp. 90-100
-
-
Nishizawa, M.1
Nishizawa, K.2
-
42
-
-
0026032209
-
Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence
-
Papazian, D.M., L.C. Timpe, Y.N. Jan, and L.Y. Jan. 1991. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature. 349:305-310. http://dx.doi.org/ 10.1038/349305a0
-
(1991)
Nature
, vol.349
, pp. 305-310
-
-
Papazian, D.M.1
Timpe, L.C.2
Jan, Y.N.3
Jan, L.Y.4
-
43
-
-
34748848687
-
Closing in on the resting state of the Shaker K(+) channel
-
Pathak, M.M., V. Yarov-Yarovoy, G. Agarwal, B. Roux, P. Barth, S. Kohout, F. Tombola, and E.Y. Isacoff. 2007. Closing in on the resting state of the Shaker K(+) channel. Neuron. 56:124-140. http://dx.doi.org/10.1016/j.neuron.2007.09.023
-
(2007)
Neuron
, vol.56
, pp. 124-140
-
-
Pathak, M.M.1
Yarov-Yarovoy, V.2
Agarwal, G.3
Roux, B.4
Barth, P.5
Kohout, S.6
Tombola, F.7
Isacoff, E.Y.8
-
44
-
-
79960621367
-
The crystal structure of a voltage-gated sodium channel
-
Payandeh, J., T. Scheuer, N. Zheng, and W.A. Catterall. 2011. The crystal structure of a voltage-gated sodium channel. Nature. 475:353-358. http://dx.doi.org/10.1038/nature10238
-
(2011)
Nature
, vol.475
, pp. 353-358
-
-
Payandeh, J.1
Scheuer, T.2
Zheng, N.3
Catterall, W.A.4
-
45
-
-
84861945912
-
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
-
Payandeh, J., T.M. Gamal El-Din, T. Scheuer, N. Zheng, and W.A. Catterall. 2012. Crystal structure of a voltage-gated sodium channel in two potentially inactivated states. Nature. 486:135-139.
-
(2012)
Nature
, vol.486
, pp. 135-139
-
-
Payandeh, J.1
Gamal El-Din, T.M.2
Scheuer, T.3
Zheng, N.4
Catterall, W.A.5
-
46
-
-
33746660275
-
A trapped intracellular cation modulates K+ channel recovery from slow inactivation
-
Ray, E.C., and C. Deutsch. 2006. A trapped intracellular cation modulates K+ channel recovery from slow inactivation. J. Gen. Physiol. 128:203-217. http://dx.doi.org/10.1085/jgp.200609561
-
(2006)
J. Gen. Physiol.
, vol.128
, pp. 203-217
-
-
Ray, E.C.1
Deutsch, C.2
-
47
-
-
0029970835
-
Transitions near the open state in Shaker K(+)-channel: probing with temperature
-
Rodríguez, B.M., and F. Bezanilla. 1996. Transitions near the open state in Shaker K(+)-channel: probing with temperature. Neuropharmacology. 35:775-785. http://dx.doi.org/10.1016/0028-3908 (96)00111-6
-
(1996)
Neuropharmacology
, vol.35
, pp. 775-785
-
-
Rodríguez, B.M.1
Bezanilla, F.2
-
48
-
-
0031870974
-
Voltage gating of Shaker K+ channels The effect of temperature on ionic and gating currents
-
Rodríguez, B.M., D. Sigg, and F. Bezanilla. 1998. Voltage gating of Shaker K+ channels. The effect of temperature on ionic and gating currents. J. Gen. Physiol. 112:223-242. http://dx.doi .org/10.1085/jgp.112.2.223
-
(1998)
J. Gen. Physiol.
, vol.112
, pp. 223-242
-
-
Rodríguez, B.M.1
Sigg, D.2
Bezanilla, F.3
-
49
-
-
0031952461
-
Activation of Shaker potassium channels III. An activation gating model for wild-type and V2 mutant channels
-
Schoppa, N.E., and F.J. Sigworth. 1998. Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J. Gen. Physiol. 111:313-342. http://dx.doi .org/10.1085/jgp.111.2.313
-
(1998)
J. Gen. Physiol.
, vol.111
, pp. 313-342
-
-
Schoppa, N.E.1
Sigworth, F.J.2
-
50
-
-
0026594721
-
The size of gating charge in wild-type and mutant Shaker potassium channels
-
Schoppa, N.E., K. McCormack, M.A. Tanouye, and F.J. Sigworth. 1992. The size of gating charge in wild-type and mutant Shaker potassium channels. Science. 255:1712-1715. http://dx.doi.org/ 10.1126/science.1553560
-
(1992)
Science
, vol.255
, pp. 1712-1715
-
-
Schoppa, N.E.1
McCormack, K.2
Tanouye, M.A.3
Sigworth, F.J.4
-
51
-
-
79953898210
-
310- helix conformation facilitates the transition of a voltage sensor S4 segment toward the down state
-
chwaiger, C.S., P. Bjelkmar, B. Hess, and E. Lindahl. 2011. 310-helix conformation facilitates the transition of a voltage sensor S4 segment toward the down state. Biophys. J. 100:1446-1454. http:// dx.doi.org/10.1016/j.bpj.2011.02.003
-
(2011)
Biophys. J.
, vol.100
, pp. 1446-1454
-
-
Schwaiger, C.S.1
Bjelkmar, P.2
Hess, B.3
Lindahl, E.4
-
52
-
-
0030175867
-
Voltagesensing residues in the S2 and S4 segments of the Shaker K+ channel
-
Seoh, S.A., D. Sigg, D.M. Papazian, and F. Bezanilla. 1996. Voltagesensing residues in the S2 and S4 segments of the Shaker K+ channel. Neuron. 16:1159-1167. http://dx.doi.org/10.1016/S0896-6273(00)80142-7
-
(1996)
Neuron
, vol.16
, pp. 1159-1167
-
-
Seoh, S.A.1
Sigg, D.2
Papazian, D.M.3
Bezanilla, F.4
-
53
-
-
0038271980
-
Fast gating in the Shaker K+ channel and the energy landscape of activation
-
Sigg, D., F. Bezanilla, and E. Stefani. 2003. Fast gating in the Shaker K+ channel and the energy landscape of activation. Proc. Natl. Acad. Sci. USA. 100:7611-7615. http://dx.doi.org/10.1073/pnas .1332409100
-
(2003)
Proc. Natl. Acad. Sci. USA.
, vol.100
, pp. 7611-7615
-
-
Sigg, D.1
Bezanilla, F.2
Stefani, E.3
-
54
-
-
0027971204
-
Voltage gating of ion channels
-
Sigworth, F.J. 1994. Voltage gating of ion channels. Q. Rev. Biophys. 27:1-40. http://dx.doi.org/10.1017/S0033583500002894
-
(1994)
Q. Rev. Biophys.
, vol.27
, pp. 1-40
-
-
Sigworth, F.J.1
-
55
-
-
1142274549
-
A proton pore in a potassium channel voltage sensor reveals a focused electric field
-
Starace, D.M., and F. Bezanilla. 2004. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 427:548-553. http://dx.doi.org/10.1038/nature02270
-
(2004)
Nature
, vol.427
, pp. 548-553
-
-
Starace, D.M.1
Bezanilla, F.2
-
56
-
-
42949089487
-
Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics
-
Trabuco, L.G., E. Villa, K. Mitra, J. Frank, and K. Schulten. 2008. Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics. Structure. 16:673-683. http:// dx.doi.org/10.1016/j.str.2008.03.005
-
(2008)
Structure
, vol.16
, pp. 673-683
-
-
Trabuco, L.G.1
Villa, E.2
Mitra, K.3
Frank, J.4
Schulten, K.5
-
57
-
-
15244339069
-
Coupled motions between pore and voltage-sensor domains: a model for Shaker B, a voltage-gated potassium channel
-
Treptow, W., B. Maigret, C. Chipot, and M. Tarek. 2004. Coupled motions between pore and voltage-sensor domains: a model for Shaker B, a voltage-gated potassium channel. Biophys. J. 87:2365-2379. http://dx.doi.org/10.1529/biophysj.104.039628
-
(2004)
Biophys. J.
, vol.87
, pp. 2365-2379
-
-
Treptow, W.1
Maigret, B.2
Chipot, C.3
Tarek, M.4
-
58
-
-
67849095786
-
Initial response of the potassium channel voltage sensor to a transmembrane potential
-
Treptow, W., M. Tarek, and M.L. Klein. 2009. Initial response of the potassium channel voltage sensor to a transmembrane potential. J. Am. Chem. Soc. 131:2107-2109. http://dx.doi.org/10.1021/ ja807330g
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 2107-2109
-
-
Treptow, W.1
Tarek, M.2
Klein, M.L.3
-
59
-
-
83355177269
-
In search of a consensus model of the resting state of a voltage-sensing domain
-
Vargas, E., F. Bezanilla, and B. Roux. 2011. In search of a consensus model of the resting state of a voltage-sensing domain. Neuron. 72:713-720. http://dx.doi.org/10.1016/j.neuron.2011.09.024
-
(2011)
Neuron
, vol.72
, pp. 713-720
-
-
Vargas, E.1
Bezanilla, F.2
Roux, B.3
-
60
-
-
78650055985
-
310 helices in channels and other membrane proteins
-
Vieira-Pires, R.S., and J.H. Morais-Cabral. 2010. 310 helices in channels and other membrane proteins. J. Gen. Physiol. 136:585-592. http://dx.doi.org/10.1085/jgp.201010508
-
(2010)
J. Gen. Physiol.
, vol.136
, pp. 585-592
-
-
Vieira-Pires, R.S.1
Morais-Cabral, J.H.2
-
61
-
-
55049100031
-
S4- based voltage sensors have three major conformations
-
Villalba-Galea, C.A., W. Sandtner, D.M. Starace, and F. Bezanilla. 2008. S4-based voltage sensors have three major conformations. Proc. Natl. Acad. Sci. USA. 105:17600-17607. http://dx.doi.org/ 10.1073/pnas.0807387105
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 17600-17607
-
-
Villalba-Galea, C.A.1
Sandtner, W.2
Starace, D.M.3
Bezanilla, F.4
-
62
-
-
33646550515
-
Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels
-
Yarov-Yarovoy, V., D. Baker, and W.A. Catterall. 2006. Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels. Proc. Natl. Acad. Sci. USA. 103:7292-7297. http://dx.doi.org/10.1073/pnas.0602350103
-
(2006)
Proc. Natl. Acad. Sci. USA.
, vol.103
, pp. 7292-7297
-
-
Yarov-Yarovoy, V.1
Baker, D.2
Catterall, W.A.3
-
63
-
-
84855998904
-
Structural basis for gating charge movement in the voltage sensor of a sodium channel
-
Yarov-Yarovoy, V., P.G. DeCaen, R.E. Westenbroek, C.Y. Pan, T. Scheuer, D. Baker, and W.A. Catterall. 2012. Structural basis for gating charge movement in the voltage sensor of a sodium channel. Proc. Natl. Acad. Sci. USA. 109:E93-E102. http://dx.doi .org/10.1073/pnas.1118434109
-
(2012)
Proc. Natl. Acad. Sci. USA.
, vol.109
-
-
Yarov-Yarovoy, V.1
DeCaen, P.G.2
Westenbroek, R.E.3
Pan, C.Y.4
Scheuer, T.5
Baker, D.6
Catterall, W.A.7
-
64
-
-
0028140472
-
Shaker potassium channel gating III: Evaluation of kinetic models for activation
-
Zagotta, W.N., T. Hoshi, and R.W. Aldrich. 1994. Shaker potassium channel gating. III: Evaluation of kinetic models for activation. J. Gen. Physiol. 103:321-362. http://dx.doi.org/10.1085/ jgp.103.2.321
-
(1994)
J. Gen. Physiol.
, vol.103
, pp. 321-362
-
-
Zagotta, W.N.1
Hoshi, T.2
Aldrich, R.W.3
-
65
-
-
84861952634
-
Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
-
Zhang, X., W. Ren, P. DeCaen, C. Yan, X. Tao, L. Tang, J. Wang, K. Hasegawa, T. Kumasaka, J. He, et al. 2012. Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature. 486:130-134. http://dx.doi.org/10.1038/486323e
-
(2012)
Nature
, vol.486
, pp. 130-134
-
-
Zhang, X.1
Ren, W.2
DeCaen, P.3
Yan, C.4
Tao, X.5
Tang, L.6
Wang, J.7
Hasegawa, K.8
Kumasaka, T.9
He, J.10
|