The zinc-binding region of IL-2 inducible T cell kinase (Itk) is required for interaction with Gα13 and activation of serum response factor

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 6, 2013, Pages 1074-1082

  Huang, Weishan ^a,b   Morales, J Luis ^b   Gazivoda, Victor P ^a   Lai, Jianbin ^a   Qi, Qian ^a,b,c   August, Avery ^a,b  

^a Department of Obstetrics Gynecology   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Btk homology domain; G protein; Serum response factor; Tec kinase

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT 13; INTERLEUKIN 2 INDUCIBLE T CELL KINASE; PHOSPHOTRANSFERASE; SERUM RESPONSE FACTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PROTEIN DOMAIN; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION INITIATION;

BINDING SITES; CELL MEMBRANE; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HUMANS; JURKAT CELLS; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; SERUM RESPONSE FACTOR; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC; ZINC;

EID: 84875932262     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.02.011     Document Type: Article

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