Absence of Tec family kinases interleukin-2 inducible T cell Kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs FcεRI-dependent mast cell responses

Journal of Biological Chemistry

Volumn 286, Issue 11, 2011, Pages 9503-9513

  Iyer, Archana S ^a,d   Morales, J Luis ^a   Huang, Weishan ^a,c   Ojo, Folake ^a   Ning, Gang ^b   Wills, Elizabeth ^c   Baines, Joel D ^c   August, Avery ^a,c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC ASTHMA; ANTIGEN RECEPTORS; BONE MARROW-DERIVED MAST CELLS; BRUTON'S TYROSINE KINASE; CALCIUM RESPONSE; CYTOKINE SECRETIONS; DEGRANULATION; EFFECTOR CELLS; IN-VITRO ANALYSIS; INTERLEUKIN-2; KNOCK OUTS; KNOCKOUT MICE; MAST CELLS; NETWORK ANALYSIS; NUCLEAR LOCALIZATION; PATHOPHYSIOLOGY; SIGNAL AMPLIFIERS; T CELLS; TYROSINE KINASE;

AMINO ACIDS; CYTOLOGY; ELECTRIC NETWORK ANALYSIS; ENZYMES; PHOSPHORYLATION; PHYSIOLOGY;

CELLS;

BRUTON TYROSINE KINASE; CALCIUM; FC RECEPTOR; FC RECEPTOR I; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN 2 INDUCIBLE T CELL KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE C GAMMA2; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT1; UNCLASSIFIED DRUG;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL GROWTH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; HISTAMINE RELEASE; IMMUNOGLOBULIN BLOOD LEVEL; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PERITONEUM MAST CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BONE MARROW CELLS; CELL NUCLEUS; CYTOKINES; MAST CELLS; MICE; MICE, KNOCKOUT; NFATC TRANSCRIPTION FACTORS; PROTEIN-TYROSINE KINASES; RECEPTORS, IGE;

MUS;

EID: 79953228472     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.165613     Document Type: Article

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