Dwarfism and increased adiposity in the gh1 mutant zebrafish vizzini

Endocrinology

Volumn 154, Issue 4, 2013, Pages 1476-1487

  McMenamin, Sarah K ^a   Minchin, James E N ^b   Gordon, Tiffany N ^a   Rawls, John F ^b   Parichy, David M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GH1 PROTEIN; GROWTH HORMONE; SOMATOMEDIN; UNCLASSIFIED DRUG;

ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY GROWTH; CALORIC RESTRICTION; CLONING; CONTROLLED STUDY; DISEASE SEVERITY; DWARFISM; GENE EXPRESSION; GROWTH RETARDATION; HOMEOSTASIS; IN VIVO STUDY; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STOP CODON; ZEBRA FISH;

ADIPOCYTES; ADIPOGENESIS; ADIPOSITY; ANIMALS; CODON, NONSENSE; DWARFISM; GROWTH HORMONE; HYPERTROPHY; OBESITY; ZEBRAFISH;

EID: 84875853620     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1734     Document Type: Article

References (84)

1. Argente J, Caballo N, Barrios V, et al. Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in prepubertal children with exogenous obesity: effect of short-and long-term weight reduction. J Clin Endocrinol Metab. 1997;82: 2076-2083.
2. Wabitsch M. Overweight and obesity in European children: definition and diagnostic procedures, risk factors and consequences for later health outcome. Eur J Pediatr. 2000;159:8-13.
3. Procter AM, Phillips JA, Cooper DN. The molecular genetics of growth hormone deficiency. Hum Genet. 1998;103:255-272.
4. Li CH, Simpson ME, Evans HM. Influence of growth and adrenocorticotropic hormones on the body composition of hypophysectomized rats. Endocrinology. 1949;44:71-75.
5. Oberbauer A, Stern J, Johnson P, et al. Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype. Growth Dev Aging. 1997;61:169.
6. Pomp D, Oberbauer AM, Murray JD. Development of obesity following inactivation of a growth hormone transgene in mice. Transgenic Res. 1996;5:13-23.
7. Waters M, Brooks A. Growth hormone receptor: structure function relationships. Horm Res Paediatr. 2011;76:12-16.
8. Han Y, Leaman DW, Watling D, et al. Participation of JAK and STAT proteins in growth hormone-induced signaling. J Biol Chem. 1996;271:5947-5952.
9. Wang X, Darus CJ, Xu BC, Kopchick JJ. Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylation and JAK2 and STAT5 activation. Mol Endocrinol. 1996;10:1249-1260.
10. Savage MO, Burren CP, Rosenfeld RG. The continuum of growth hormone-IGF-I axis defects causing short stature: diagnostic and therapeutic challenges. Clin Endocrinol (Oxf). 2010;72:721-728.
11. Walenkamp MJE, Wit JM. Genetic disorders in the growth hormone-insulin-like growth factor-I axis. Hormone Res. 2006;66: 221-230.
12. Forsyth IA, Wallis M. Growth hormone and prolactin-molecular and functional evolution. J Mammary Gland Biol Neoplasia. 2002; 7:291-312.
13. Kawauchi H, Suzuki K, Yamazaki T, et al. Identification of growth hormone in the sea lamprey, an extant representative of a group of the most ancient vertebrates. Endocrinology. 2002;143:4916-4921.
14. Reinecke M, Björnsson BT, Dickhoff WW, et al. Growth hormone and insulin-like growth factors in fish: whereweare and where to go. Gen Comp Endocrinol. 2005;142:20-24.
15. Wallis M. The molecular evolution of vertebrate growth hormones: a pattern of near-stasis interrupted by sustained bursts of rapid change. J Mol Evol. 1996;43:93-100.
16. Zou S, Kamei H, Modi Z, Duan C. Zebrafish IGF genes: gene duplication, conservation and divergence, and novel roles in midline and notochord development. PLoS One. 2009;4:e7026.
17. Chen M, Huang X, Yuen DSH, Cheng CHK. A study on the functional interaction between the GH/PRL family of polypeptides with their receptors in zebrafish: evidence against GHR1 being the receptor for somatolactin. Mol Cell Endocrinol. 2011;337:114-121.
18. Sun K, Kusminski CM, Scherer PE. Adipose tissue remodeling and obesity. J Clin Invest. 2011;121:2094.
19. Kopelman PG. Obesity as a medical problem. Nature. 2000;404: 635-643.
20. Bonnet F, Vanderschueren-Lodeweyckx M, Eeckels R, Malvaux P. Subcutaneous adipose tissue and lipids in blood in growth hormone deficiency before and after treatment with human growth hormone. Pediatr Res. 1974;8:800-805.
21. Bengtsson BÅ, Eden S, Lönn L, et al. Treatment of adults with growth hormone (GH) deficiency with recombinant human GH. J Clin Endocrinol Metab. 1993;76:309-317.
22. Salomon F, Cuneo RC, Hesp R, Sönksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. New Engl J Med. 1989;321:1797-1803.
23. Morikawa M, Nixon T, Green H. Growth hormone and the adipose conversion of 3T3 cells. Cell. 1982;29:783-789.
24. Wabitsch M, Braun S, Hauner H, et al. Mitogenic and antiadipogenic properties of human growth hormone in differentiating human adipocyte precursor cells in primary culture1. Pediatr Res. 1996;40:450-456.
25. Wabitsch M, Heinze E, Hauner H, et al. Biological effects of human growth hormone in rat adipocyte precursor cells and newly differentiated adipocytes in primary culture. Metabolism. 1996;45:34-42.
26. Moller L, Dalman L, Norrelund H, et al. Impact of fasting on growth hormone signaling and action in muscle and fat. J Clin Endocrinol Metab. 2009;94:965-972.
27. Nam SY, Marcus C. Growth hormone and adipocyte function in obesity. Horm Res Paediatr. 2000;53:87-97.
28. Flynn EJ, Trent CM, Rawls JF. Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio). J Lipid Res. 2009;50:1641-1652.
29. Elizondo MR, Budi EH, Parichy DM. Trpm7 regulation of in vivo cation homeostasis and kidney function involves stanniocalcin 1 and fgf23. Endocrinology. 2010;151:5700.
30. Song Y, Cone RD. Creation of a genetic model of obesity in a teleost. FASEB J. 2007;21:2042-2049.
31. Holtta-Vuori M, Salo V, Nyberg L, et al. Zebrafish: gaining popularity in lipid research. Biochem J. 2010;429:235-242.
32. Tingaud-Sequeira A, Ouadah N, Babin PJ. Zebrafish obesogenic test: a tool for screening molecules that target adiposity. J Lipid Res. 2011;52:1765-1772.
33. Imrie D, Sadler KC. White adipose tissue development in zebrafish is regulated by both developmental time and fish size. Dev Dyn. 2010;239:3013-3023.
34. Parichy DM, Elizondo MR, Mills MG, Gordon TN, Engeszer RE. Normal table of postembryonic zebrafish development: staging by externally visible anatomy of the living fish. Dev Dyn. 2009;238: 2975-3015.
35. Minchin J, Rawls JF. In vivo analysis of white adipose tissue in zebrafish. Methods Cell Biol. 2011;105:63-86.
36. Solnica-Krezel L, Schier AF, Driever W. Efficient recovery of ENUinduced mutations from the zebrafish germline. Genetics. 1994;136: 1401-1420.
37. Farmanfarmaian A, Sun LZ. Growth hormone effects on essential amino acid absorption, muscle amino acid profile, N-retention and nutritional requirements of striped bass hybrids. Genet Anal: Biomol Eng. 1999;15:107-113.
38. Shved N, Berishvili G, Mazel P, Baroiller JF, Eppler E. Growth hormone (GH) treatment acts on the endocrine and autocrine/paracrine GH/IGF-axis and on TNF-α expression in bony fish pituitary and immune organs. Fish Shellfish Immunol. 2011;31:944-952.
39. Raven P, Sakhrani D, Beckman B, et al. Growth and endocrine effects of recombinant bovine growth hormone treatment in nontransgenic and growth hormone transgenic coho salmon. Gen Comp Endocrinol. 2012;177:143-152.
40. Schneider CA, Rasband WS, Eliceiri KW. NIH image to ImageJ: 25 years of image analysis. Nat Methods. 2012;9:671-675.
41. Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF. Stages of embryonic development of the zebrafish. Dev Dyn. 1995; 203:253-310.
42. R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria:RFoundation for Statistical Computing; 2012.
43. JMP. Version 8.0. Cary, North Carolina: SAS Institute, Inc; 2009.
44. Rozen S, Skaletsky HJ. Primer3 on theWWWfor general users and for biologist programmers. Totowa, New Jersey: Humana Press; 2000.
45. Afonina I, Ankoudinova I, Mills A, Lokhov S, Huynh P, Mahoney W. Primers with 5′ flaps improve real-time PCR. BioTechniques. 2007;43:770-776.
46. Isaksson OGP, Edén S, Jansson JO, Lindahl A, Isgaard J, Nilsson A. Sites of action of growth hormone on somatic growth. J Anim Sci. 1986;63:48-56.
47. Laron Z. Insulin-like growth factor 1 (IGF-1): a growth hormone. Mol Pathol. 2001;54:311-316.
48. Wood AW, Duan C, Bern HA. Insulin-like growth factor signaling in fish. Int Rev Cytol. 2005;243:215-285.
49. Duan C. The insulin-like growth factor system and its biological actions in fish. Am Zool. 1997;37:491-503.
50. Shamblott MJ, Cheng CM, Bolt D, Chen TT. Appearance of insulinlike growth factor mRNA in the liver and pyloric ceca of a teleost in response to exogenous growth hormone. Proc Natl Acad Sci USA. 1995;92:6943.
51. Davidson MB. Effect of growth hormone on carbohydrate and lipid metabolism. Endocr Rev. 1987;8:115-131.
52. Press M. Growth hormone and metabolism. Diabetes Metab Rev. 1988;4:391-414.
53. Berryman DE, List EO, Sackmann-Sala L, Lubbers E, Munn R, Kopchick JJ. Growth hormone and adipose tissue: beyond the adipocyte. Growth Horm IGF Res. 2011;21:113-123.
54. Palmer AJ, Chung MY, List EO, et al. Age-related changes in body composition of bovine growth hormone transgenic mice. Endocrinology. 2009;150:1353-1360.
55. Farese Jr RV, Walther TC. Lipid droplets finally get a little RESPECT. Cell. 2009;139:855-860.
56. Rodeheffer MS, Birsoy K, Friedman JM. Identification of white adipocyte progenitor cells in vivo. Cell. 2008;135:240-249.
57. Shen W, Wang ZM, Punyanita M, et al. Adipose tissue quantification by imaging methods: a proposed classification. Obesity Res. 2012;11:5-16.
58. Berryman DE, List EO, Coschigano KT, Behar K, Kim JK, Kopchick JJ. Comparing adiposity profiles in three mouse models with altered GH signaling. Growth Horm IGF Res. 2004;14:309-318.
59. Moreau D, Fleming I, Fletcher G, Brown J. Growth hormone transgenesis does not influence territorial dominance or growth and survival of first-feeding Atlantic salmon Salmo salar in food-limited stream microcosms. J Fish Biol. 2011;78:726-740.
60. Rahman MA, Maclean N. Growth performance of transgenic tilapia containing an exogenous piscine growth hormone gene. Aquaculture. 1999;173:333-346.
61. Devlin R, Johnsson J, Smailus D, Biagi C, Jönsson E, Björnsson BT. Increased ability to compete for food by growth hormone-transgenic coho salmon Oncorhynchus kisutch (Walbaum). Aquacult Res. 1999;30:479-482.
62. Mori T, Devlin RH. Transgene and host growth hormone gene expression in pituitary and nonpituitary tissues of normal and growth hormone transgenic salmon. Mol Cell Endocrinol. 1999;149:129-139.
63. Ofir R, Gootwine E. Ovine growth hormone gene duplication-structural and evolutionary implications. Mamm Genome. 1997;8: 770-772.
64. Pogoda H-M, Hardt Svd, Herzog W, Krame C, Schwarz H, Hammerschmidt M. The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis. Development. 2011;133:1079-1089.
65. Zhu Y, Song D, Tran N-T, Nguyen N. The effects of the members of growth hormone family knockdown in zebrafish development. Gen Comp Endocrinol. 2007;150:395-404.
66. Gluckman PD, Pinal CS. Regulation of fetal growth by the somatotrophic axis. J Nutr. 2003;133:1741S-1746S.
67. Møller N, Jørgensen JOL. Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr Rev. 2009; 30:152-177.
68. Jo J, Gavrilova O, Pack S, et al. Hypertrophy and/or hyperplasia: dynamics of adipose tissue growth. PLoS Comp Biol. 2009;5: e1000324.
69. Jo J, Guo J, Liu T, et al. Hypertrophy-driven adipocyte death overwhelms recruitment under prolonged weight gain. Biophys J. 2010; 99:3535-3544.
70. MacKellar J, Cushman SW, Periwal V. Waves of adipose tissue growth in the genetically obese Zucker fatty rat. PLoS One. 2010; 5:e8197.
71. Nishimura S, Manabe I, Nagasaki M, et al. In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J Clin Invest. 2008;118:710.
72. Nishimura S, Manabe I, Nagasaki M, et al. Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes. 2007;56:1517-1526.
73. Meyer CWE, Korthaus D, Jagla W, et al. A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity. Endocrinology. 2004;145:2531-2541.
74. Zhou Y, Xu BC, Maheshwari HG, et al. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proc Natl Acad Sci USA. 1997;94:13215-13220.
75. Li S, Crenshaw EB, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature. 1990; 347:528-533.
76. Flurkey K, Papaconstantinou J, Miller RA, Harrison DE. Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc Natl Acad Sci USA. 2001;98:6736-6741.
77. Wabitsch M, Hauner H, Heinze E, Teller WM. The role of growth hormone/insulin-like growth factors in adipocyte differentiation. Metabolism. 1995;44:45-49.
78. Cotta OR, Santarpia L, Curtó L, et al. Primary growth hormone insensitivity (Laron syndrome) and acquired hypothyroidism: a case report. JMCR. 2011;5:301.
79. Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, et al. Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med. 2011;3:70ra13.
80. Li Y, Knapp JR, Kopchick JJ. Enlargement of interscapular brown adipose tissue in growth hormone antagonist transgenic and in growth hormone receptor gene-disrupted dwarf mice. Exp Biol Med. 2003;228:207-215.
81. Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ. Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology. 2003;144:3799-3810.
82. Flint DJ, Binart N, Boumard S, Kopchick JJ, Kelly P. Developmental aspects of adipose tissue inGHreceptor and prolactin receptor gene disrupted mice: site-specific effects upon proliferation, differentiation and hormone sensitivity. J Endocrinol. 2006;191:101-111.
83. OkaT, Nishimura Y, Zang L, et al. Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity. BMC Physiol. 2010;10:21.
84. Tainaka T, Shimada Y, Kuroyanagi J, et al. Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish dietinduced obesity model. Nutr Metab. 2011;8:88.