Growth hormone and prolactin - Molecular and functional evolution

Journal of Mammary Gland Biology and Neoplasia

Volumn 7, Issue 3, 2002, Pages 291-312

  Forsyth, Isabel A ^a   Wallis, Michael ^b  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Adaptive molecular evolution; Biological effects; Function switching; Receptors; Sites of synthesis; Vertebrates

Indexed keywords

AMINO ACID; BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; MESSENGER RNA; PLACENTA LACTOGEN; PROLACTIN; PROLACTIN RECEPTOR; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN;

ADAPTATION; DIMERIZATION; EVOLUTION; GENE DUPLICATION; GENE EXPRESSION REGULATION; GROWTH REGULATION; HORMONE RECEPTOR INTERACTION; HUMAN; MAMMARY GLAND; NONHUMAN; PRIMATE; REVIEW;

ANIMALS; EVOLUTION, MOLECULAR; GROWTH HORMONE; HUMANS; LACTATION; PROLACTIN; RECEPTORS, CELL SURFACE;

EID: 1642619546     PISSN: 10833021     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022804817104     Document Type: Review

References (125)

1. A. A. Kossiakoff and A. de Vos (1999). Structural basis for cytokine hormone-receptor recognition and receptor activation. Adv. Protein Chem. 52:67-108.
2. M. Wallis (1992). The expanding growth hormone/prolactin family. J. Mol. Endocrinol. 9:185-188.
3. D. May, J. Alrubaian, S. Patel, R. M. Dores, and M. Rand-Weaver (1999). Studies on the GH/SL gene family: Cloning of African lungfish (Protopterus annectens) growth hormone and somatolactin and toad (Bufo marinus) growth hormone. Gen. Comp. Endocrinol. 113:121-135.
4. Y. Amemiya, Y. Sogabe, M. Nozaki, A.Takahashi, and H. Kawauchi (1999). Somatolactin in the white sturgeon and African lungfish and its evolutionary significance. Gen. Comp. Endocrinol. 114:181-190.
5. D. Sankoff (2001). Gene and genome duplication. Curr. Opin. Genet. Dev. 11:681-684.
6. I. A. Forsyth (1994). Comparative aspects of placental lactogens - Structure and function. Exp. Clin. Endocrinol. 102:244-251.
7. M. Wallis, A. Lioupis, and O. C. Wallis (1998). Duplicate growth hormone genes in sheep and goat. J. Mol. Endocrinol. 21:1-5.
8. U. J. Lewis, R. N. P. Singh, Y. N. Singh, and W. P. Vanderlaan (1985). Glycosylated human-prolactin. Endocrinology 116:359-363.
9. C. S. Nicoll, G. L. Mayer, and S. M. Russell (1986). Structural features of prolactins and growth hormones that can be related to their biological properties. Endocr. Rev. 7:169-203.
10. S. S. Abdel-Meguid, H.-S. Shieh, W. W. Smith, H. E. Dayringer, B. N. Violand, and L. A. Bentle (1987). Three-dimensional structure of a genetically engineered variant of porcine growth hormone. Proc. Nat. Acad. Sci. U.S.A. 84:6434-6437.
11. A. M. de Vos, M. Ultsch, and A. A. Kossiakoff (1992). Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex. Science 255:306-312.
12. L. Chantalat, N. D. Jones, F. Korber, J. Navaza, and A. G. Pavlovsky (1995). The crystal structure of wild-type growth hormone at 2.5 Å resolution. Prot. Pept. Letts. 2:333-340.
13. V. Goffin, J. A. Martial, and N. L. Summers (1995). Use of a model to understand prolactin and growth hormone specificities. Protein Eng. 8:1215-1231.
14. D. Halaby, E. Thoreau, J. Djiane, and J.-P. Mornon (1997). Homology modeling of rabbit prolactin hormone complexed with its receptor. PROTEINS Struct. Function Genetics 27:459-468.
15. P. A. Elkins, H. W. Christinger, Y. Sandowski, E. Sakal, A. Gertler, A. M. de Vos, and A. A. Kossiakoff (2000). Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor. Nat. Struct. Biol. 7:808-815.
16. M. Wallis (1989). Species specificity and structure-function relationships of growth hormone. In R. B. Heap, C. G. Prosser, and G. E. Lamming (eds.), Biotechnology in Growth Regulation, Butterworths, London, pp. 3-14.
17. S. N. Behncken, S. W. Rowlinson, J. E. Rowland, B. L. Conway-Campbell, T. A. Monks, and M. J. Waters (1997). Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor. J. Biol. Chem. 272:27077-27083.
18. S. C. Souza, G. P. Frick, X. Wang, J. J. Kopchick, R. B. Lobo, and H. M. Goodman (1995). A single arginine residue determines species specificity of the human growth hormone receptor. Proc. Nat. Acad. Sci. U.S.A. 92:959-963.
19. M. Wallis (1996). The molecular evolution of vertebrate growth hormones: A pattern of near-stasis interrupted by sustained bursts of rapid change. J. Mol. Evol. 43:93-100.
20. U. J. Lewis, L. F. Bonewald, and L. J. Lewis (1980). The 20,000-dalton variant of human growth hormone: Location of the amino acid deletion. Biochem. Biophys. Res. Commun. 92:511-516.
21. Y. N. Sinha (1995). Structural variants of prolactin: Occurrence and physiological significance. Endocr. Rev. 16:354-369.
22. C. Clapp, J. A. Martial, R. C. Guzman, F. Rentierdelrue, and R. I. Weiner (1993). The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology 133:1292-1299.
23. W. L. Miller and N. L. Eberhardt (1983). Structure and evolution of the growth hormone gene family. Endocr. Rev. 4:97-130.
24. E. Y. Chen, Y.-C. Liao, D. H. Smith, H. A. Barrera-Saldana, R. E. Gelinas, and P. H. Seeburg (1989). The human growth hormone locus: Nucleotide sequence, biology, and evolution. Genomics 4:479-497.
25. E. Alsat, J. Guibourdenche, D. Luton, F. Frankenne, and D. Evain-Brion (1997). Human placental growth hormone. Am. J. Obst. Gynecol. 177:1526-1534.
26. O. C. Wallis, Y.-P. Zhang, and M. Wallis (2001). Molecular evolution of growth hormone (GH) in primates. Characterisation of the GH genes from slow loris and marmoset defines an episode of rapid evolutionary change. J. Mol. Endocrinol. 26:249-258.
27. R. M. Adkins, A. Nekrutenko, and W.-H. Li (2001). Bush-baby growth hormone is much more similar to nonprimate growth hormones than to rhesus monkey and human growth hormone. Mol. Biol. Evol. 18:55-60.
28. O. C. Wallis and M. Wallis (2002). Characterisation of the growth hormone gene cluster in a new world monkey, the marmoset (Callithrix jacchus). J. Mol. Endocrinol. 29:89-97.
29. T. G. Golos, M. Durning, J. M. Fisher, and P. D. Fowler (1993). Cloning of four growth hormone/chorionic somatomammotropin-related complementary deoxyribonucleic acids differentially expressed during pregnancy in the rhesus monkey placenta. Endocrinology 133:1744-1752.
30. A. B. Dietz, M. Georges, D. W. Threadgill, J. E. Womack, and L. A. Schuler (1992). Somatic-cell mapping, polymorphism, and linkage analysis of bovine prolactin-related proteins and placental-lactogen. Genomics 14:137-143.
31. P. Shah, Y. X. Sun, C. Szpirer, and M. L. Duckworth (1998). Rat placental lactogen II gene: Characterization of gene structure and placental-specific expression. Endocrinology 139:967-973.
32. K. E. Orwig, R. Ishimura, H. Muller, B. Liu, and M. J. Soares (1997). Identification and characterization of a mouse homolog for decidual/trophoblast prolactin-related protein. Endocrinology 138:5511-5517.
33. N. L. Eberhardt, S.-W. Jiang, A. R. Shepard, A. M. Arnold, and M. A. Trujillo (1996). Hormonal and cell-specific regulation of the human growth hormone and chorionic somatomammotropin genes. Progr. Nucleic. Acid Res. Mol. Biol. 54:127-163.
34. V. Goffin, N. Binart, P. Touraine, and P. A. Kelly (2002). Prolactin: The new biology of an old hormone. Ann. Rev. Physiol. 64:47-67.
35. I. M. Bennani-Baiti, B. K. Jones, S. A. Liebhaber, and N. E. Cooke (1995). Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel □-subunit gene (SCN4A) on chromosome 17. Genomics 29:647-652.
36. N. A. Chuzhanova, M. Krawczak, L. A. Nemytikova, V. D. Gusev, and D. N. Cooper (2000). Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene. Gene 254:9-18.
37. M. Wallis (1994). Variable evolutionary rates in the molecular evolution of mammalian growth hormones. J. Mol. Evol. 38:619-627.
38. D. Graur and W-H. Li (2000). Fundamentals of Molecular Evolution, 2nd edn., Sinauer, Sunderland, MA.
39. M. Wallis (2001). Episodic evolution of protein hormones in mammals. J. Mol. Evol. 53:10-18.
40. J.-C. Liu, K. D. Makova, R. M. Adkins, S. Gibson, and W.-H. Li (2001). Episodic evolution of growth hormone in primates and emergence of the species specificity of human growth hormone receptor. Mol. Biol. Evol. 18:945-953.
41. R. M. Adkins, J. Vandenberg, and W.-H. Li (2000). Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone. Gene 246:357-363.
42. G. Bernardi, G. D'Onofrio, S. Caccio, and G. Bernardi (1993). Molecular phylogeny of bony fishes, based on the amino acid sequence of the growth hormone. J. Mol. Evol. 37:644-649.
43. M. Wallis (2000). Episodic evolution of protein hormones: Molecular evolution of pituitary prolactin. J. Mol. Evol. 50:465-473.
44. J. D. Curlewis, M. C. Saunders, J. Kuang, G. A. Harrison, and D. W. Cooper (1998). Cloning and sequence analysis of a pituitary prolactin cDNA from the brushtail possum (Trichosurus vulpecula). Gen. Comp. Endocrinol. 111:61-67.
45. M. Wallis (1997). Function switching as a basis for bursts of rapid change during the evolution of pituitary growth hormone. J. Mol. Evol. 44:348-350.
46. H. A. Barrera-Saldana (1998). Growth hormone and placental lactogen: Biology, medicine and biotechnology. Gene 211:11-18.
47. T. Ohta (1993). Pattern of nucleotide substitutions in growth hormone-prolactin gene family: A paradigm for evolution by gene duplication. Genetics 134:1271-1276.
48. M. C. Lacroix, E. Devinoy, J. L. Servely, C. Puissant, and G. Kann (1996). Expression of the growth hormone gene in ovine placenta: Detection and cellular localization of the protein. Endocrinology 137:4886-4892.
49. O. C. Wallis and M. Wallis (2001). Molecular evolution of growth hormone (GH) in Cetartiodactyla: Cloning and characterization of the gene encoding GH from a primitive ruminant, the chevrotain (Tragulus javanicus). Gen. Comp. Endocrinol. 123:62-72.
50. L. A. Schuler and M. A. Kessler (1992). Bovine placental prolactin-related hormones. Trends Endocrinol. Metab. 3:334-338.
51. V. Goffin, K. T. Shiverick, P. A. Kelly, and J. A. Martial (1996). Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen, and related proteins in mammals. Endocr. Rev. 17:385-410.
52. P. Colosi, G. Thordarson, R. Hellmiss, K. Singh, I. A. Forsyth, P. Gluckman, and W. I. Wood (1989). Cloning and expression of ovine placental lactogen. Mol. Endocrinol. 3:1462-1469.
53. E. Sakal, C. Bignon, N. Chapnik-Cohen, N. Daniel, J. Paly, L. Belair, J. Djiane, and A. Gertler (1998). Cloning, preparation and characterization of biologically active recombinant caprine placental lactogen. J. Endocrinol. 159:509-518.
54. M. Wallis (1993). Remarkably high rate of molecular evolution of ruminant placental lactogens. J. Mol. Evol. 37:86-88.
55. J. Lin, D. J. Toft, N. W. Bengtson, and D. I. H. Linzer (2000). Placental prolactins and the physiology of pregnancy. Recent Prog. Horm. Res. 55:37-52.
56. J. N. Southard, L. Do, W. C. Smith, and F. Talamantes (1989). Hamster placental lactogen-II contains a structural feature unique among the growth hormone-prolactin-placental lactogen family. Mol. Endocrinol. 3:1710-1713.
57. P. B. Vrana, P. G. Matteson, J. V. Schmidt, R. S. Ingram, A. Joyce, K. L. Prince, M. J. Dewey, and S. M. Tilghman (2001). Genomic imprinting of a placental lactogen gene in Peromyscus. Dev. Genes Evol. 211:523-532.
58. P. A. Kelly, J. Djiane, M.-C. Postel-Vinay, and M. Edery (1991). The prolactin/growth hormone receptor family. Endocr. Rev. 12:235-251.
59. V. Goffin and P. A. Kelly (1997). The prolactin/growth hormone receptor family: Structure/function relationships. J. Mam. Gland Biol. Neoplasia 2:7-17.
60. H. N. Jabbour and P. A. Kelly (1997). Prolactin receptor subtypes: A possible mode of tissue specific regulation of prolactin function. Rev. Reprod. 2:14-18.
61. X. J. Chen and N. D. Horseman (1994). Cloning, expression and mutational analysis of the pigeon prolactin receptor. Endocrinology 135:269-276.
62. C. G. Goodyer, G. Zogopoulos, G. Schwartzbauer, H. Zheng, G. N. Hendy, and R. K. Menon (2001). Organization and evolution of the human growth hormone receptor gene 5′-flanking region. Endocrinology 142:1923-1934.
63. M. Ballesteros, K.-C. Leung, R. J. M. Ross, T. P. Iismaa, and K. K. Y. Ho (2000). Distribution and abundance of messenger ribonucleic acid for growth hormone receptor isoforms in human tissues. J. Clin. Endocrinol. Metab. 85:2865-2871.
64. M. C. Postel-Vinay (1996). Growth hormone-and prolactin-binding proteins: Soluble forms of receptors. Horm. Res. 45:178-181.
65. G. Baumann (2001). Growth hormone binding protein 2001. J. Pediatr. Endocrinol. Metab. 14:355-375.
66. Z.-Z. Hu, L. Zhuang, and M. L. Dufau (1998). Prolactin receptor gene diversity: Structure and regulation. Trends Endocrinol. Metab. 9:94-101.
67. Z.-Z. Hu, J. Meng, and M. L. Dufau (2001). Isolation and characterization of two novel forms of the human prolactin receptor generated by aternative splicing of a newly identified exon 11. J. Biol. Chem. 276:41086-41094.
68. R. Das and B. K. Vonderhaar (1995). Transduction of prolactin's (PRL) growth signal through both long and short forms of the PRL receptor. Mol. Endocrinol. 9:1750-1759.
69. C. Bignon, N. Daniel, L. Blair, and J. Djiane (1999). In vitro expression of long and short ovine prolactin receptors: Activation of Jak2/ STAT5 pathway is not sufficient to account for prolactin signal transduction to the ovine beta-lactoglobulin gene promoter. J. Mol. Endocrinol. 23:125-136.
70. J. B. Kline and C. V. Clevenger (2001). Identification and characterization of the prolactin-binding protein in human serum and milk. J. Biol. Chem. 276:24760-24766.
71. W. Somers, M. Ultsch, A. M. de Vos, and A. A. Kossiakoff (1994). The X-ray structure of a growth hormone-prolactin receptor complex. Nature 372:478-481.
72. T. Amit, Z. Hochberg, M. J. Waters, and R. J. Barkey (1992). Growth hormone-and prolactin-binding proteins in mammalian serum. Endocrinology 131:1793-1803.
73. J. Pantel, K. Machinis, M.-L. Sobrier, P. Duquesnoy, M. Goossens, and S. Amselem (2000). Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution. J. Biol. Chem. 275:18664-18669.
74. J. A. Wells (1996). Binding in the growth hormone receptor complex. Proc. Natl. Acad. Sci. U.S.A. 93:1-6.
75. C. Bole-Feysot, V. Goffin, M. Edery, N. Binart, and P. A. Kelly (1998). Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr. Rev. 19:255-268.
76. J. Nakae, Y. Kido, and D. Accili (2001). Distinct and overlapping functions of insulin and IGF-I receptors. Endocr. Rev. 22:818-835.
77. R. Pincus-Kramarski, I. Alroy, and Y. Yarden (1977). ErbB receptors and EGF-like ligands: Cell lineage determination and oncogenesis through combinatorial signaling. J. Mam. Gland Biol. Neoplasia 2:97-107.
78. A. Herman, C. Bignon, N. Daniel, J. Grosclaude, A. Gertler, and J. Djiane (2000). Functional heterodimerization of prolactin and growth hormone receptors by ovine placental lactogen. J. Biol. Chem. 275:6295-6301.
79. D. Helman, A. Herman, J. Paly, O. Livnah, P. A. Elkins, A. M. de Vos, J. Djiane, and A. Gertler (2001). Mutations of ovine and bovine placental lactogens change, in different ways, the biological activity mediated through homologous and heterologous lactogenic receptors. J. Endocrinol. 169:43-54.
80. A. Herman, D. Helman, O. Livnah, and A. Gertler (1999). Ruminant placental lactogens act as antagonists to homologous growth hormone receptors and as agonists to human or rabbit growth hormone receptors. J. Biol. Chem. 274:7631-7639.
81. H. Leibovich, A. Gertler, F. Bazer, and E. Gootwine (2001). Effects of recombinant ovine placental lactogen and recombinant ovine growth hormone on growth of lambs and milk production in ewes. Livestock Prod. Sci. 68:79-86.
82. B. C. Cunningham, S. Bass, G. Fuh, and J. A. Wells (1990). Zinc mediation of the binding of human growth hormone to the human prolactin receptor. Science 250:1709-1712.
83. M. L. Hartman (2000). Physiological regulators of growth hormone secretion. In A. Juhl and J. O. L. Jorgensen (eds.), Growth Hormone in Adults. Physiological and Clinical Aspects, 2nd edn., Cambridge University Press, Cambridge, pp. 3-53.
84. K. Takaya, H. Ariyasu, N. Kanamoto, H. Iwakura, A. Yoshimoto, M. Harada, K. Mori, Y. Komatsu, T. Usui, A. Shimatsu, Y. Ogawa, K. Hosoda, T. Akamizu, M. Kokima, K. Kangawa, and K. Nakao (2000). Gherilin strongly stimulates growth hormone (GH) release in humans. J. Clin. Endocrinol. Metab. 85:4908-4911.
85. N. Ben-Jonathan and R. Hnasko (2001). Dopamine as a prolactin (PRL) inhibitor. Endocr. Rev. 22:724-763.
86. D. R. Grattan (2002). Behavioural significance of prolactin signalling in the central nervous system during pregnancy and lactation. Reproduction 123:497-506.
87. N. Liu, H. C. Mertani, G. Norstedt, J. Tornell, and P. E. Lobie (1997). Mode of the autocrine/paracrine mechanism of growth hormone action. Exp. Cell Res. 237:196-206.
88. S. Harvey and K. Hull (1997). Growth hormone: A paracrine growth factor? Endocrine 7:267-279.
89. N. Ben-Jonathan, J. L. Mershon, D. L. Allen, and R. W. Steinmetz (1996). Extrapituitary prolactin: Distribution, regulation, functions, and clinical aspects. Endocr. Rev. 17:639-669.
90. M. E. Freeman, B. Kanyicska, A. Lerant, and G. Nagy (2000). Prolactin: Structure, function, and regulation of secretion. Physiol. Rev. 80:1523-1631.
91. J. A. Mol, E. van Garderen, G. R. Rutteman, and A. Rijnberk (1996). New insights in the molecular mechanism of progestin-induced proliferation of the mammary epithelium: Induction of the local biosynthesis of growth hormone (GH) in the mammary gland of dogs, cats and humans. J. Steroid Biochem. Molec. Biol. 57:67-71.
92. E. Nagy and I. Berczi (1991). Hypophysectomized rats depend on residual prolactin for survival. Endocrinology 128:2776-2784.
93. K. L. Hull and S. Harvey (2000). Growth hormone: A reproductive endocrine-paracrine regulator? Rev. Reprod. 5:175-182.
94. Y. Lee and J. L. Voogt (1999). Feedback effects of placental lactogens on prolactin levels and fos-related antigen immunoreactivity of tuberoinfundibular dopaminergic neurons in the arcuate nucleus during pregnancy in the rat. Endocrinology 140:2159-2166.
95. D. Haig (1993). Generic conflicts in human pregnancy. Quarterly Rev. Biol. 68:495-532.
96. D. Le Roith, C. Bondy, S. Yakar, J.-L. Liu, and A. Butler (2001). The somatomedin hypothesis: 2001. Endocr. Rev. 22:53-74.
97. A. C. Schmid, M. Reinecke, and W. Kloas (2000). Primary cultured hepatocytes of the bony fish, Oreochromis mossambicus, the tilapia: A valid tool for physiological studies on IGF-I expression in liver. J. Endocrinol. 166:265-273.
98. M. Tanaka, Y. Hayashida, K. Sakaguchi, T. Ohkuba, M. Wakita, S. Hoshino, and K. Nakashima (1996). Growth hormone-independent expression of insulin-like growth factor I messenger ribonucleic acid in extrahepatic tissues of the chicken. Endocrinology 137:30-34.
99. H. A. Bern (1986). Functional evolution of prolactin and growth hormone in lower vertebrates. Amer. Zool. 23:663-671.
100. J. R. Tata (1996). Metamorphosis: An exquisite model for hormonal regulation of post-embryonic development. Biochem. Soc. Symp. 62:123-136.
101. H. T. Blair, S. N. McCutcheon, D. D. Mackenzie, J. E. Ormsby, R. A. Siddiqui, B. H. Breier, and P. D. Gluckman (1988). Genetic selection for insulin-like growth factor-1 in growing mice is associated with altered growth. Endocrinology 123:1690-1692.
102. Y. Zhou, B. C. Xu, H. G. Maheshwari, L. He, M. Reed, M. Lozykowski, S. Okada, L. Cataldo, K. Coschigamo, T. E. Wagner, G. Baumann, and J. J. Kopchick (1997). A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proc. Natl. Acad. Sci. U.S.A. 94:13215-13220.
103. W. M. Drake, S. J. Howell, J. P. Monson, and S. M. Shallet (2001 ). Optimizing GH therapy in adults and children. Endocr. Rev. 22:425-450.
104. P. J. Jenkins and G. M. Besser (2001). Acromegaly and cancer: A problem. J. Clin. Endocrinol. Metab. 86:2935-2941.
105. J. Arendt (1995). Melatonin and the Mammalian Pineal Gland, Chapman and Hall, London.
106. L. L. Badhura and B. D. Goldman (1992). Prolactin-dependent seasonal changes in pelage: Role of the pineal gland and dopamine. J. Exp. Zool. 33:27-33.
107. G. A. Lincoln and I. I. Clarke (1994). Photoperiodically-induced cycles in the secretion of hypothalamo-pituitary disconnected rams: Evidence for the translation of the melatonin signal in the pituitary gland. J. Neuroendocrinol. 6:251-260.
108. M. B. Renfree (1994). Endocrinology of pregnancy, parturition and lactation in marsupials. In G. E. Lamming (ed.), Marshall's Physiology of Reproduction, 4th edn., Chapman and Hall, London, pp. 677-766.
109. R. Nowak, R. H. Porter, F. Levy, P. Orgeur, and B. Schaal (2000). Role of mother-young interactions in the survival of offspring in domestic mammals. Rev. Reprod. 5:153-163.
110. B. K. Vonderhaar (1999). Proactin involvement in breast cancer. Endocr. Relat. Cancer 6:389-404.
111. H. L. Buttle (1978). The maintenance of pregnancy in hypophysectomized goats. J. Reprod. Fertil. 52:255-260.
112. H. Leibovich, A. Gertler, F. W. Bazer, and E. Gootwine (2000). Active immunization of ewes against placental lactogen increases birth weight of lambs and milk production with no adverse effect on conception rate. Anim. Reprod. Sci. 64:33-47.
113. W. H. Walker, S. L. Fitzpatrick, H. A. Barrera-Saldana, D. Resendez-Perez, and G. F. Saunders (1991). The human placental lactogen genes: Structure, function, evolution and transcriptional regulation. Endoc. Rev. 12:316-328.
114. M. I. Gallego, N. Binart, G. W. Robinson, R. Okagaki, K. T. Coschigano, J. Perry, J. J. Kopchick, T. Oka, P. A. Kelly, and L. Hennighausen (2001). Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects. Dev. Biol. 229:163-175.
115. M. C. Neville, T. B. McFadden, and I. Forsyth (2002). Hormonal regulation of mammary differentiation and milk secretion. J. Mam. Gland Biol. Neoplasia 7:49-66.
116. D. L. Kleinberg, M. Feldman, and W. Ruan (2000). IGF-I: An essential factor in terminal end bud formation and ductal morphogenesis. J. Mam. Gland Biol. Neoplasia 5:7-17.
117. R. M. Akers, T. B. McFadden, S. Purup, M. Vestergaard, K. Sejrsen, and A. V. Capuco (2000). Local IGF-I axis in peripubertal ruminant mammry development. J. Mam. Gland Biol. Neoplasia 5:43-51.
118. I. D. Johnsson (1988). The effect of prepubertal nutrition on lactation performance by dairy cows. In P. C. Garnsworthy (ed.), Nutrition and Lactation in the Dairy Cow, Butterworths, London, pp. 171-192.
119. A. W. Bell and D. E. Baumann (1997). Adaptaions of glucose metabolism during pregnancy and lactation. J. Mam. Gland Biol. Neoplasia 2:265-278.
120. I. A. Forsyth, J. A. Taylor, G. Gabai, and I. R. Fleet (1995). Blood prolactin concentrations affect prolactin transfer into goat milk: Implications for maintenance of lactation. J. Endocrinol. 146:411-420.
121. J. C. Taylor and M. Peaker (1975). The effects of bromocrytine on milk secretion in the rabbit. J. Endocrinol. 67:313-314.
122. D. J. Flint and M. Gardner (1994). Evidence that growth hormone stimulates milk synthesis by direct action on the mammary gland and that prolactin exerts effects on milk secretion by maintenance of mammary dexoxyribonucleic acid content and tight junction status. Endocrinology 135:1119-1124.
123. D.-A. Nguyen, A. F. Parlow, and M. C. Neville (2001). Hormonal regulation of tight junction closure in the mouse mammary epithelium during the transition from pregnancy to lactation. J. Endocrinol. 170:347-356.
124. D. J. Flint, E. Tonner, and G. J. Allan (2000). Insulin-like growth factor binding proteins: IGF-dependent and -independent effects in the mammary gland. J. Mam. Gland Biol. Neoplasia 5:65-73.
125. A. S. McNeilly (2001). Lactational control of reproduction. Reprod. Fertil. Dev. 13:583-590.