HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 6, 2013, Pages 1443-1453

  Siepi, Francesca ^a   Gatti, Veronica ^a   Camerini, Serena ^b   Crescenzi, Marco ^b   Soddu, Silvia ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Activation loop Y; DYRK; HIPK2; Phosphorylation; Posttranslational modification; Subcellular localization

Indexed keywords

HOMEODOMAIN INTERACTING PROTEIN KINASE 2; PURVALANOL A;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CHROMATOGRAPHY, LIQUID; CYTOPLASM; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; MICE; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBCELLULAR FRACTIONS; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY; THREONINE; TYROSINE;

EID: 84875762375     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.02.018     Document Type: Article

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