메뉴 건너뛰기




Volumn 59, Issue , 2013, Pages 139-147

p90RSKs mediate the activation of ribosomal RNA synthesis by the hypertrophic agonist phenylephrine in adult cardiomyocytes

Author keywords

Cardiomyocyte; Hypertrophy; MAP kinase; p90RSK; Ribosome biogenesis

Indexed keywords

BID 1870; DNA DIRECTED RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE III; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLEPHRINE; PROTEIN RSK P90; PROTEIN SERINE THREONINE KINASE INHIBITOR; RAPAMYCIN; RIBOSOME RNA; S6 KINASE; SL 0101; UNCLASSIFIED DRUG; TARGET OF RAPAMYCIN KINASE;

EID: 84875643640     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.03.006     Document Type: Article
Times cited : (23)

References (55)
  • 2
    • 0036842351 scopus 로고    scopus 로고
    • Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes
    • Wang, L., Proud, C.G., Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes. Circ Res 91 (2002), 821–829.
    • (2002) Circ Res , vol.91 , pp. 821-829
    • Wang, L.1    Proud, C.G.2
  • 3
    • 0035980049 scopus 로고    scopus 로고
    • Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes
    • Wang, L., Gout, I., Proud, C.G., Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes. J Biol Chem 276 (2001), 32670–32677.
    • (2001) J Biol Chem , vol.276 , pp. 32670-32677
    • Wang, L.1    Gout, I.2    Proud, C.G.3
  • 4
    • 0037032451 scopus 로고    scopus 로고
    • Regulation of the phosphorylation of elongation factor 2 by MEK-dependent signalling in adult rat cardiomyocytes
    • Wang, L., Proud, C.G., Regulation of the phosphorylation of elongation factor 2 by MEK-dependent signalling in adult rat cardiomyocytes. FEBS Lett 531 (2002), 285–289.
    • (2002) FEBS Lett , vol.531 , pp. 285-289
    • Wang, L.1    Proud, C.G.2
  • 5
    • 0037032451 scopus 로고    scopus 로고
    • Regulation of the phosphorylation of elongation factor 2 by MEK-dependent signalling in adult rat cardiomyocytes
    • Wang, L., Proud, C.G., Regulation of the phosphorylation of elongation factor 2 by MEK-dependent signalling in adult rat cardiomyocytes. FEBS Lett 531 (2002), 285–289.
    • (2002) FEBS Lett , vol.531 , pp. 285-289
    • Wang, L.1    Proud, C.G.2
  • 6
    • 21744446249 scopus 로고    scopus 로고
    • Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2)
    • Rolfe, M., McLeod, L.E., Pratt, P.F., Proud, C.G., Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2). Biochem J 388 (2005), 973–984.
    • (2005) Biochem J , vol.388 , pp. 973-984
    • Rolfe, M.1    McLeod, L.E.2    Pratt, P.F.3    Proud, C.G.4
  • 7
  • 9
    • 33750044901 scopus 로고    scopus 로고
    • Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases
    • Mayer, C., Grummt, I., Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases. Oncogene 25 (2006), 6384–6391.
    • (2006) Oncogene , vol.25 , pp. 6384-6391
    • Mayer, C.1    Grummt, I.2
  • 10
    • 77955287244 scopus 로고    scopus 로고
    • mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1
    • Kantidakis, T., Ramsbottom, B.A., Birch, J.L., Dowding, S.N., White, R.J., mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proc Natl Acad Sci U S A 107 (2010), 11823–11828.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11823-11828
    • Kantidakis, T.1    Ramsbottom, B.A.2    Birch, J.L.3    Dowding, S.N.4    White, R.J.5
  • 13
  • 14
    • 84555189440 scopus 로고    scopus 로고
    • Regulation and function of the RSK family of protein kinases
    • Romeo, Y., Zhang, X., Roux, P.P., Regulation and function of the RSK family of protein kinases. Biochem J 441 (2012), 553–569.
    • (2012) Biochem J , vol.441 , pp. 553-569
    • Romeo, Y.1    Zhang, X.2    Roux, P.P.3
  • 16
    • 0034107580 scopus 로고    scopus 로고
    • Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps
    • Wang, L., Wang, X., Proud, C.G., Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps. Am J Physiol Heart Circ Physiol 278 (2000), H1056–H1068.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , pp. H1056-H1068
    • Wang, L.1    Wang, X.2    Proud, C.G.3
  • 17
    • 84859366546 scopus 로고    scopus 로고
    • mTOR signaling regulates the processing of pre-rRNA in human cells
    • Iadevaia, V., Zhang, Z., Jan, E., Proud, C.G., mTOR signaling regulates the processing of pre-rRNA in human cells. Nucleic Acids Res 40 (2012), 2527–2539.
    • (2012) Nucleic Acids Res , vol.40 , pp. 2527-2539
    • Iadevaia, V.1    Zhang, Z.2    Jan, E.3    Proud, C.G.4
  • 18
    • 0008817735 scopus 로고    scopus 로고
    • Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells
    • del SB, Valdes R., Mata, J., Felipe, A., Casado, F.J., Pastor-Anglada, M., Differential expression and regulation of nucleoside transport systems in rat liver parenchymal and hepatoma cells. Hepatology 28 (1998), 1504–1511.
    • (1998) Hepatology , vol.28 , pp. 1504-1511
    • del SB, V.R.1    Mata, J.2    Felipe, A.3    Casado, F.J.4    Pastor-Anglada, M.5
  • 19
    • 1642351825 scopus 로고    scopus 로고
    • ATP-sensitive K(+) channels regulate the concentrative adenosine transporter CNT2 following activation by A(1) adenosine receptors
    • Duflot, S., Riera, B., Fernandez-Veledo, S., Casado, V., Norman, R.I., Casado, F.J., et al. ATP-sensitive K(+) channels regulate the concentrative adenosine transporter CNT2 following activation by A(1) adenosine receptors. Mol Cell Biol 24 (2004), 2710–2719.
    • (2004) Mol Cell Biol , vol.24 , pp. 2710-2719
    • Duflot, S.1    Riera, B.2    Fernandez-Veledo, S.3    Casado, V.4    Norman, R.I.5    Casado, F.J.6
  • 20
    • 13844281888 scopus 로고    scopus 로고
    • Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay
    • Cleary, M.D., Meiering, C.D., Jan, E., Guymon, R., Boothroyd, J.C., Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay. Nat Biotechnol 23 (2005), 232–237.
    • (2005) Nat Biotechnol , vol.23 , pp. 232-237
    • Cleary, M.D.1    Meiering, C.D.2    Jan, E.3    Guymon, R.4    Boothroyd, J.C.5
  • 21
    • 0024287697 scopus 로고
    • Selective isolation of newly synthesized mammalian mRNA after in vivo labeling with 4-thiouridine or 6-thioguanosine
    • Woodford, T.A., Schlegel, R., Pardee, A.B., Selective isolation of newly synthesized mammalian mRNA after in vivo labeling with 4-thiouridine or 6-thioguanosine. Anal Biochem 171 (1988), 166–172.
    • (1988) Anal Biochem , vol.171 , pp. 166-172
    • Woodford, T.A.1    Schlegel, R.2    Pardee, A.B.3
  • 22
    • 75149141045 scopus 로고    scopus 로고
    • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
    • [714]
    • Mann, J., Chu, D.C., Maxwell, A., Oakley, F., Zhu, N.L., Tsukamoto, H., et al. MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 138 (2010), 705–714 [714].
    • (2010) Gastroenterology , vol.138 , pp. 705-714
    • Mann, J.1    Chu, D.C.2    Maxwell, A.3    Oakley, F.4    Zhu, N.L.5    Tsukamoto, H.6
  • 23
    • 20844440353 scopus 로고    scopus 로고
    • MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
    • Poortinga, G., Hannan, K.M., Snelling, H., Walkley, C.R., Jenkins, A., Sharkey, K., et al. MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation. EMBO J 23 (2004), 3325–3335.
    • (2004) EMBO J , vol.23 , pp. 3325-3335
    • Poortinga, G.1    Hannan, K.M.2    Snelling, H.3    Walkley, C.R.4    Jenkins, A.5    Sharkey, K.6
  • 24
    • 0035462613 scopus 로고    scopus 로고
    • Increased expression of UBF is a critical determinant for rRNA synthesis and hypertrophic growth of cardiac myocytes
    • Brandenburger, Y., Jenkins, A., Autelitano, D.J., Hannan, R.D., Increased expression of UBF is a critical determinant for rRNA synthesis and hypertrophic growth of cardiac myocytes. FASEB J 15 (2001), 2051–2053.
    • (2001) FASEB J , vol.15 , pp. 2051-2053
    • Brandenburger, Y.1    Jenkins, A.2    Autelitano, D.J.3    Hannan, R.D.4
  • 25
    • 0042236377 scopus 로고    scopus 로고
    • Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF
    • Brandenburger, Y., Arthur, J.F., Woodcock, E.A., Du, X.J., Gao, X.M., Autelitano, D.J., et al. Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF. FEBS Lett 548 (2003), 79–84.
    • (2003) FEBS Lett , vol.548 , pp. 79-84
    • Brandenburger, Y.1    Arthur, J.F.2    Woodcock, E.A.3    Du, X.J.4    Gao, X.M.5    Autelitano, D.J.6
  • 28
    • 11144356304 scopus 로고    scopus 로고
    • S6K1(−/−)/S6K2(−/−) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
    • Pende, M., Um, S.H., Mieulet, V., Sticker, M., Goss, V.L., Mestan, J., et al. S6K1(−/−)/S6K2(−/−) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol Cell Biol 24 (2004), 3112–3124.
    • (2004) Mol Cell Biol , vol.24 , pp. 3112-3124
    • Pende, M.1    Um, S.H.2    Mieulet, V.3    Sticker, M.4    Goss, V.L.5    Mestan, J.6
  • 29
    • 33947401129 scopus 로고    scopus 로고
    • Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor
    • Yeh, T.C., Marsh, V., Bernat, B.A., Ballard, J., Colwell, H., Evans, R.J., et al. Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor. Clin Cancer Res 13 (2007), 1576–1583.
    • (2007) Clin Cancer Res , vol.13 , pp. 1576-1583
    • Yeh, T.C.1    Marsh, V.2    Bernat, B.A.3    Ballard, J.4    Colwell, H.5    Evans, R.J.6
  • 30
    • 33846312875 scopus 로고    scopus 로고
    • BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo
    • Sapkota, G.P., Cummings, L., Newell, F.S., Armstrong, C., Bain, J., Frodin, M., et al. BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J 401 (2007), 29–38.
    • (2007) Biochem J , vol.401 , pp. 29-38
    • Sapkota, G.P.1    Cummings, L.2    Newell, F.S.3    Armstrong, C.4    Bain, J.5    Frodin, M.6
  • 31
    • 37549028779 scopus 로고    scopus 로고
    • Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
    • Jastrzebski, K., Hannan, K.M., Tchoubrieva, E.B., Hannan, R.D., Pearson, R.B., Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function. Growth Factors 25 (2007), 209–226.
    • (2007) Growth Factors , vol.25 , pp. 209-226
    • Jastrzebski, K.1    Hannan, K.M.2    Tchoubrieva, E.B.3    Hannan, R.D.4    Pearson, R.B.5
  • 32
    • 61349141302 scopus 로고    scopus 로고
    • Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2
    • Feldman, M.E., Apsel, B., Uotila, A., Loewith, R., Knight, Z.A., Ruggero, D., et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol, 7, 2009, e38.
    • (2009) PLoS Biol , vol.7 , pp. e38
    • Feldman, M.E.1    Apsel, B.2    Uotila, A.3    Loewith, R.4    Knight, Z.A.5    Ruggero, D.6
  • 33
    • 15044340650 scopus 로고    scopus 로고
    • Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins
    • Wang, X., Beugnet, A., Murakami, M., Yamanaka, S., Proud, C.G., Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins. Mol Cell Biol 25 (2005), 2558–2572.
    • (2005) Mol Cell Biol , vol.25 , pp. 2558-2572
    • Wang, X.1    Beugnet, A.2    Murakami, M.3    Yamanaka, S.4    Proud, C.G.5
  • 34
    • 65549145048 scopus 로고    scopus 로고
    • An ATP-competitive mTOR inhibitor reveals rapamycin-insensitive functions of mTORC1
    • Thoreen, C.C., Kang, S.A., Chang, J.W., Liu, Q., Zhang, J., Gao, Y., et al. An ATP-competitive mTOR inhibitor reveals rapamycin-insensitive functions of mTORC1. J Biol Chem 284 (2009), 8023–8032.
    • (2009) J Biol Chem , vol.284 , pp. 8023-8032
    • Thoreen, C.C.1    Kang, S.A.2    Chang, J.W.3    Liu, Q.4    Zhang, J.5    Gao, Y.6
  • 35
    • 56249147509 scopus 로고    scopus 로고
    • Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
    • Choo, A.Y., Yoon, S.O., Kim, S.G., Roux, P.P., Blenis, J., Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation. Proc Natl Acad Sci U S A 105 (2008), 17414–17419.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 17414-17419
    • Choo, A.Y.1    Yoon, S.O.2    Kim, S.G.3    Roux, P.P.4    Blenis, J.5
  • 36
    • 70449584566 scopus 로고    scopus 로고
    • AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply
    • Hoppe, S., Bierhoff, H., Cado, I., Weber, A., Tiebe, M., Grummt, I., et al. AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc Natl Acad Sci U S A 106 (2009), 17781–17786.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 17781-17786
    • Hoppe, S.1    Bierhoff, H.2    Cado, I.3    Weber, A.4    Tiebe, M.5    Grummt, I.6
  • 37
    • 11144252845 scopus 로고    scopus 로고
    • PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway
    • Dokladda, K., Green, K.A., Pan, D.A., Hardie, D.G., PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway. FEBS Lett 579 (2005), 236–240.
    • (2005) FEBS Lett , vol.579 , pp. 236-240
    • Dokladda, K.1    Green, K.A.2    Pan, D.A.3    Hardie, D.G.4
  • 38
    • 65649090185 scopus 로고    scopus 로고
    • Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic beta-cells
    • Moore, C.E., Xie, J., Gomez, E., Herbert, T.P., Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic beta-cells. J Mol Biol 389 (2009), 480–494.
    • (2009) J Mol Biol , vol.389 , pp. 480-494
    • Moore, C.E.1    Xie, J.2    Gomez, E.3    Herbert, T.P.4
  • 40
    • 52449095361 scopus 로고    scopus 로고
    • The RSK family of kinases: emerging roles in cellular signalling
    • Anjum, R., Blenis, J., The RSK family of kinases: emerging roles in cellular signalling. Nat Rev Mol Cell Biol 9 (2008), 747–758.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 747-758
    • Anjum, R.1    Blenis, J.2
  • 41
    • 79961011264 scopus 로고    scopus 로고
    • Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90RSK in the control of mTORC1 protein signaling by phorbol esters
    • Fonseca, B.D., Alain, T., Finestone, L.K., Huang, B.P., Rolfe, M., Jiang, T., et al. Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90RSK in the control of mTORC1 protein signaling by phorbol esters. J Biol Chem 286 (2011), 27111–27122.
    • (2011) J Biol Chem , vol.286 , pp. 27111-27122
    • Fonseca, B.D.1    Alain, T.2    Finestone, L.K.3    Huang, B.P.4    Rolfe, M.5    Jiang, T.6
  • 42
    • 84874051746 scopus 로고    scopus 로고
    • p90 ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq protein-coupled receptor stimuli, endothelin-1 and alpha1-adrenergic receptor agonists
    • Amirak, E., Fuller, S.J., Sugden, P.H., Clerk, A., p90 ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq protein-coupled receptor stimuli, endothelin-1 and alpha1-adrenergic receptor agonists. Biochem J 450 (2012), 351–363.
    • (2012) Biochem J , vol.450 , pp. 351-363
    • Amirak, E.1    Fuller, S.J.2    Sugden, P.H.3    Clerk, A.4
  • 43
    • 70349782278 scopus 로고    scopus 로고
    • Differential regulation of NHE1 phosphorylation and glucose uptake by inhibitors of the ERK pathway and p90RSK in 3T3-L1 adipocytes
    • Chen, S., MacKintosh, C., Differential regulation of NHE1 phosphorylation and glucose uptake by inhibitors of the ERK pathway and p90RSK in 3T3-L1 adipocytes. Cell Signal 21 (2009), 1984–1993.
    • (2009) Cell Signal , vol.21 , pp. 1984-1993
    • Chen, S.1    MacKintosh, C.2
  • 44
    • 13444270324 scopus 로고    scopus 로고
    • Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation
    • Smith, J.A., Poteet-Smith, C.E., Xu, Y., Errington, T.M., Hecht, S.M., Lannigan, D.A., Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res 65 (2005), 1027–1034.
    • (2005) Cancer Res , vol.65 , pp. 1027-1034
    • Smith, J.A.1    Poteet-Smith, C.E.2    Xu, Y.3    Errington, T.M.4    Hecht, S.M.5    Lannigan, D.A.6
  • 46
    • 0037291736 scopus 로고    scopus 로고
    • ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth
    • Zhao, J., Yuan, X., Frodin, M., Grummt, I., ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. Mol Cell 11 (2003), 405–413.
    • (2003) Mol Cell , vol.11 , pp. 405-413
    • Zhao, J.1    Yuan, X.2    Frodin, M.3    Grummt, I.4
  • 47
    • 14144254701 scopus 로고    scopus 로고
    • Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors
    • Ballif, B.A., Roux, P.P., Gerber, S.A., Mackeigan, J.P., Blenis, J., Gygi, S.P., Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors. Proc Natl Acad Sci U S A 102 (2005), 667–672.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 667-672
    • Ballif, B.A.1    Roux, P.P.2    Gerber, S.A.3    Mackeigan, J.P.4    Blenis, J.5    Gygi, S.P.6
  • 48
    • 51049083138 scopus 로고    scopus 로고
    • Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
    • Carriere, A., Cargnello, M., Julien, L.A., Gao, H., Bonneil, E., Thibault, P., et al. Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation. Curr Biol 18 (2008), 1269–1277.
    • (2008) Curr Biol , vol.18 , pp. 1269-1277
    • Carriere, A.1    Cargnello, M.2    Julien, L.A.3    Gao, H.4    Bonneil, E.5    Thibault, P.6
  • 49
    • 4544384577 scopus 로고    scopus 로고
    • Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
    • Roux, P.P., Ballif, B.A., Anjum, R., Gygi, S.P., Blenis, J., Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. Proc Natl Acad Sci U S A 101 (2004), 13489–13494.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13489-13494
    • Roux, P.P.1    Ballif, B.A.2    Anjum, R.3    Gygi, S.P.4    Blenis, J.5
  • 50
    • 84862822434 scopus 로고
    • Involvement of ERK-RSK cascade in phenylephrine-induced phosphorylation of GATA4
    • Li, T., Liu, Z., Hu, X., Ma, K., Zhou, C., Involvement of ERK-RSK cascade in phenylephrine-induced phosphorylation of GATA4. Biochim Biophys Acta 2012 (1823), 582–592.
    • (1823) Biochim Biophys Acta , vol.2012 , pp. 582-592
    • Li, T.1    Liu, Z.2    Hu, X.3    Ma, K.4    Zhou, C.5
  • 51
    • 0025836713 scopus 로고
    • Phorbol ester stimulation of protein kinase C activity and ribosomal DNA transcription. Role in hypertrophic growth of cultured cardiomyocytes
    • Allo, S.N., McDermott, P.J., Carl, L.L., Morgan, H.E., Phorbol ester stimulation of protein kinase C activity and ribosomal DNA transcription. Role in hypertrophic growth of cultured cardiomyocytes. J Biol Chem 266 (1991), 22003–22009.
    • (1991) J Biol Chem , vol.266 , pp. 22003-22009
    • Allo, S.N.1    McDermott, P.J.2    Carl, L.L.3    Morgan, H.E.4
  • 52
    • 0024443882 scopus 로고
    • Accelerated rates of ribosomal RNA synthesis during growth of contracting heart cells in culture
    • McDermott, P.J., Rothblum, L.I., Smith, S.D., Morgan, H.E., Accelerated rates of ribosomal RNA synthesis during growth of contracting heart cells in culture. J Biol Chem 264 (1989), 18220–18227.
    • (1989) J Biol Chem , vol.264 , pp. 18220-18227
    • McDermott, P.J.1    Rothblum, L.I.2    Smith, S.D.3    Morgan, H.E.4
  • 53
    • 40649117625 scopus 로고    scopus 로고
    • Targeting Na +/H + exchanger regulation for cardiac protection: a RSKy approach?
    • Avkiran, M., Cook, A.R., Cuello, F., Targeting Na +/H + exchanger regulation for cardiac protection: a RSKy approach?. Curr Opin Pharmacol 8 (2008), 133–140.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 133-140
    • Avkiran, M.1    Cook, A.R.2    Cuello, F.3
  • 54
    • 59149099065 scopus 로고    scopus 로고
    • Estrogen exerts concentration-dependent pro-and anti-hypertrophic effects on adult cultured ventricular myocytes. Role of NHE-1 in estrogen-induced hypertrophy
    • Kilic, A., Javadov, S., Karmazyn, M., Estrogen exerts concentration-dependent pro-and anti-hypertrophic effects on adult cultured ventricular myocytes. Role of NHE-1 in estrogen-induced hypertrophy. J Mol Cell Cardiol 46 (2009), 360–369.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 360-369
    • Kilic, A.1    Javadov, S.2    Karmazyn, M.3
  • 55
    • 85028115496 scopus 로고    scopus 로고
    • Anchored p90 ribosomal S6 kinase 3 is required for cardiac myocyte hypertrophy
    • Li, J., Kritzer, M.D., Michel, J.J., Le, A., Thakur, H., Gayanilo, M., et al. Anchored p90 ribosomal S6 kinase 3 is required for cardiac myocyte hypertrophy. Circ Res 112 (2013), 128–139.
    • (2013) Circ Res , vol.112 , pp. 128-139
    • Li, J.1    Kritzer, M.D.2    Michel, J.J.3    Le, A.4    Thakur, H.5    Gayanilo, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.