Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes

Circulation Research

Volumn 91, Issue 9, 2002, Pages 821-829

  Wang, Lijun ^a   Proud, Christopher G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cardiac hypertrophy; eIF4E binding protein 1; MEK; mRNA translation; S6 kinase 1

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; ENDOTHELIN 1; G PROTEIN COUPLED RECEPTOR; INITIATION FACTOR 4E; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLEPHRINE; PROTEIN KINASE B; RAPAMYCIN; RAS PROTEIN; S6 KINASE; WORTMANNIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HEART HYPERTROPHY; HEART MUSCLE CELL; IMMUNOBLOTTING; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; RNA TRANSLATION;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; CARDIOMEGALY; CARRIER PROTEINS; CELLS, CULTURED; ENDOTHELIN-1; ENZYME INHIBITORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEART; HETEROTRIMERIC GTP-BINDING PROTEINS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; PHENYLEPHRINE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; RAS PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIROLIMUS;

EID: 0036842351     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000041029.97988.E9     Document Type: Article

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