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Volumn 24, Issue 3, 2013, Pages 172-178

Neuropilin signalling in vessels, neurons and tumours

Author keywords

Angiogenesis; Cancer; Neural crest cell; Neuron; Neuropilin; Semaphorin; VEGF

Indexed keywords

NEUROPILIN; NEUROPILIN 1; NEUROPILIN 2; VASCULOTROPIN A; VASCULOTROPIN C;

EID: 84875631991     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2013.01.001     Document Type: Review
Times cited : (72)

References (109)
  • 2
    • 84858841220 scopus 로고    scopus 로고
    • Diverse roles for VEGF-A in the nervous system
    • Mackenzie F., Ruhrberg C. Diverse roles for VEGF-A in the nervous system. Development 2012, 139:1371-1380.
    • (2012) Development , vol.139 , pp. 1371-1380
    • Mackenzie, F.1    Ruhrberg, C.2
  • 3
    • 77449085256 scopus 로고    scopus 로고
    • Neuropilin, you gotta let me know: should I stay or should I go?
    • Schwarz Q., Ruhrberg C. Neuropilin, you gotta let me know: should I stay or should I go?. Cell Adhesion & Migration 2010, 4:61-66.
    • (2010) Cell Adhesion & Migration , vol.4 , pp. 61-66
    • Schwarz, Q.1    Ruhrberg, C.2
  • 5
    • 0037124068 scopus 로고    scopus 로고
    • Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165
    • Gu C., Limberg B.J., Whitaker G.B., Perman B., Leahy D.J., Rosenbaum J.S., et al. Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. The Journal of Biological Chemistry 2002, 277:18069-18076.
    • (2002) The Journal of Biological Chemistry , vol.277 , pp. 18069-18076
    • Gu, C.1    Limberg, B.J.2    Whitaker, G.B.3    Perman, B.4    Leahy, D.J.5    Rosenbaum, J.S.6
  • 7
    • 0038686623 scopus 로고    scopus 로고
    • Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
    • Gu C., Rodriguez E.R., Reimert D.V., Shu T., Fritzsch B., Richards L.J., et al. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Developmental Cell 2003, 5:45-57.
    • (2003) Developmental Cell , vol.5 , pp. 45-57
    • Gu, C.1    Rodriguez, E.R.2    Reimert, D.V.3    Shu, T.4    Fritzsch, B.5    Richards, L.J.6
  • 11
    • 41049094181 scopus 로고    scopus 로고
    • A pioneer in the study of angiogenesis
    • Ribatti D., Judah Folkman A pioneer in the study of angiogenesis. Angiogenesis 2008, 11:3-10.
    • (2008) Angiogenesis , vol.11 , pp. 3-10
    • Ribatti, D.1    Judah, F.2
  • 14
    • 47949089077 scopus 로고    scopus 로고
    • VEGF-targeted therapy: mechanisms of anti-tumour activity
    • Ellis L.M., Hicklin D.J. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nature Reviews Cancer 2008, 8:579-591.
    • (2008) Nature Reviews Cancer , vol.8 , pp. 579-591
    • Ellis, L.M.1    Hicklin, D.J.2
  • 16
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • Tischer E., Mitchell R., Hartman T., Silva M., Gospodarowicz D., Fiddes J.C., et al. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. The Journal of Biological Chemistry 1991, 266:11947-11954.
    • (1991) The Journal of Biological Chemistry , vol.266 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fiddes, J.C.6
  • 17
    • 0027751890 scopus 로고
    • The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
    • Park J.E., Keller G.A., Ferrara N. The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Molecular Biology of the Cell 1993, 4:1317-1326.
    • (1993) Molecular Biology of the Cell , vol.4 , pp. 1317-1326
    • Park, J.E.1    Keller, G.A.2    Ferrara, N.3
  • 18
    • 0027064888 scopus 로고
    • Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
    • Houck K.A., Leung D.W., Rowland A.M., Winer J., Ferrara N. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. The Journal of Biological Chemistry 1992, 267:26031-26037.
    • (1992) The Journal of Biological Chemistry , vol.267 , pp. 26031-26037
    • Houck, K.A.1    Leung, D.W.2    Rowland, A.M.3    Winer, J.4    Ferrara, N.5
  • 19
    • 0037108152 scopus 로고    scopus 로고
    • Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis
    • Ruhrberg C., Gerhardt H., Golding M., Watson R., Ioannidou S., Fujisawa H., et al. Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes & Development 2002, 16:2684-2698.
    • (2002) Genes & Development , vol.16 , pp. 2684-2698
    • Ruhrberg, C.1    Gerhardt, H.2    Golding, M.3    Watson, R.4    Ioannidou, S.5    Fujisawa, H.6
  • 21
    • 84859488831 scopus 로고    scopus 로고
    • Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1
    • Parker M.W., Xu P., Li X., Vander Kooi C.W. Structural basis for selective vascular endothelial growth factor-A (VEGF-A) binding to neuropilin-1. The Journal of Biological Chemistry 2012, 287:11082-11089.
    • (2012) The Journal of Biological Chemistry , vol.287 , pp. 11082-11089
    • Parker, M.W.1    Xu, P.2    Li, X.3    Vander Kooi, C.W.4
  • 22
    • 8644219642 scopus 로고    scopus 로고
    • Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve
    • Schwarz Q., Gu C., Fujisawa H., Sabelko K., Gertsenstein M., Nagy A., et al. Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. Genes & Development 2004, 18:2822-2834.
    • (2004) Genes & Development , vol.18 , pp. 2822-2834
    • Schwarz, Q.1    Gu, C.2    Fujisawa, H.3    Sabelko, K.4    Gertsenstein, M.5    Nagy, A.6
  • 23
    • 79958044393 scopus 로고    scopus 로고
    • VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm
    • Erskine L., Reijntjes S., Pratt T., Denti L., Schwarz Q., Vieira J.M., et al. VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron 2011, 70:951-965.
    • (2011) Neuron , vol.70 , pp. 951-965
    • Erskine, L.1    Reijntjes, S.2    Pratt, T.3    Denti, L.4    Schwarz, Q.5    Vieira, J.M.6
  • 24
    • 80051490622 scopus 로고    scopus 로고
    • VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels
    • Cariboni A., Davidson K., Dozio E., Memi F., Schwarz Q., Stossi F., et al. VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Development 2011, 138:3723-3733.
    • (2011) Development , vol.138 , pp. 3723-3733
    • Cariboni, A.1    Davidson, K.2    Dozio, E.3    Memi, F.4    Schwarz, Q.5    Stossi, F.6
  • 25
    • 0034674108 scopus 로고    scopus 로고
    • Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165
    • Gluzman-Poltorak Z., Cohen T., Herzog Y., Neufeld G. Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165. The Journal of Biological Chemistry 2000, 275:18040-18045.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 18040-18045
    • Gluzman-Poltorak, Z.1    Cohen, T.2    Herzog, Y.3    Neufeld, G.4
  • 27
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker S., Takashima S., Miao H.Q., Neufeld G., Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 1998, 92:735-745.
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 29
    • 0033520916 scopus 로고    scopus 로고
    • A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability
    • Stacker S.A., Vitali A., Caesar C., Domagala T., Groenen L.C., Nice E., et al. A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability. The Journal of Biological Chemistry 1999, 274:34884-34892.
    • (1999) The Journal of Biological Chemistry , vol.274 , pp. 34884-34892
    • Stacker, S.A.1    Vitali, A.2    Caesar, C.3    Domagala, T.4    Groenen, L.C.5    Nice, E.6
  • 30
    • 43149106665 scopus 로고    scopus 로고
    • Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival
    • Wang L., Dutta S.K., Kojima T., Xu X., Khosravi-Far R., Ekker S.C., et al. Neuropilin-1 modulates p53/caspases axis to promote endothelial cell survival. PLoS ONE 2007, 2:e1161.
    • (2007) PLoS ONE , vol.2
    • Wang, L.1    Dutta, S.K.2    Kojima, T.3    Xu, X.4    Khosravi-Far, R.5    Ekker, S.C.6
  • 31
    • 79952255709 scopus 로고    scopus 로고
    • Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells
    • Evans I.M., Yamaji M., Britton G., Pellet-Many C., Lockie C., Zachary I.C., et al. Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Molecular and Cellular Biology 2011, 31:1174-1185.
    • (2011) Molecular and Cellular Biology , vol.31 , pp. 1174-1185
    • Evans, I.M.1    Yamaji, M.2    Britton, G.3    Pellet-Many, C.4    Lockie, C.5    Zachary, I.C.6
  • 32
    • 33845678052 scopus 로고    scopus 로고
    • C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis
    • Wang L., Mukhopadhyay D., Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB Journal 2006, 20:1513-1515.
    • (2006) FASEB Journal , vol.20 , pp. 1513-1515
    • Wang, L.1    Mukhopadhyay, D.2    Xu, X.3
  • 33
    • 80052515065 scopus 로고    scopus 로고
    • The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins
    • Fantin A., Schwarz Q., Davidson K., Normando E.M., Denti L., Ruhrberg C. The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins. Development 2011, 138:4185-4191.
    • (2011) Development , vol.138 , pp. 4185-4191
    • Fantin, A.1    Schwarz, Q.2    Davidson, K.3    Normando, E.M.4    Denti, L.5    Ruhrberg, C.6
  • 34
    • 0034097594 scopus 로고    scopus 로고
    • Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state
    • Haigh J.J., Gerber H.P., Ferrara N., Wagner E.F. Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state. Development 2000, 127:1445-1453.
    • (2000) Development , vol.127 , pp. 1445-1453
    • Haigh, J.J.1    Gerber, H.P.2    Ferrara, N.3    Wagner, E.F.4
  • 36
  • 38
    • 33747152506 scopus 로고    scopus 로고
    • Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
    • Favier B., Alam A., Barron P., Bonnin J., Laboudie P., Fons P., et al. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood 2006, 108:1243-1250.
    • (2006) Blood , vol.108 , pp. 1243-1250
    • Favier, B.1    Alam, A.2    Barron, P.3    Bonnin, J.4    Laboudie, P.5    Fons, P.6
  • 41
    • 78149477118 scopus 로고    scopus 로고
    • Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1
    • Ruiz de Almodovar C., Coulon C., Salin P.A., Knevels E., Chounlamountri N., Poesen K., et al. Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1. The Journal of Neuroscience 2010, 30:15052-15066.
    • (2010) The Journal of Neuroscience , vol.30 , pp. 15052-15066
    • Ruiz de Almodovar, C.1    Coulon, C.2    Salin, P.A.3    Knevels, E.4    Chounlamountri, N.5    Poesen, K.6
  • 43
    • 78650528556 scopus 로고    scopus 로고
    • Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism
    • Cariboni A., Davidson K., Rakic S., Maggi R., Parnavelas J.G., Ruhrberg C. Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism. Human Molecular Genetics 2011, 20:336-344.
    • (2011) Human Molecular Genetics , vol.20 , pp. 336-344
    • Cariboni, A.1    Davidson, K.2    Rakic, S.3    Maggi, R.4    Parnavelas, J.G.5    Ruhrberg, C.6
  • 44
  • 46
    • 84855486320 scopus 로고    scopus 로고
    • Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer
    • Sakurai A., Doci C.L., Gutkind J.S. Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer. Cell Research 2012, 22:23-32.
    • (2012) Cell Research , vol.22 , pp. 23-32
    • Sakurai, A.1    Doci, C.L.2    Gutkind, J.S.3
  • 49
    • 84875577582 scopus 로고    scopus 로고
    • The role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development
    • Oh W.J., Gu C. The role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development. Seminars in Cell & Developmental Biology 2012.
    • (2012) Seminars in Cell & Developmental Biology
    • Oh, W.J.1    Gu, C.2
  • 50
    • 0027373701 scopus 로고
    • Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones
    • Luo Y., Raible D., Raper J.A. Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones. Cell 1993, 75:217-227.
    • (1993) Cell , vol.75 , pp. 217-227
    • Luo, Y.1    Raible, D.2    Raper, J.A.3
  • 51
    • 0030987542 scopus 로고    scopus 로고
    • Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection
    • Taniguchi M., Yuasa S., Fujisawa H., Naruse I., Saga S., Mishina M., et al. Disruption of semaphorin III/D gene causes severe abnormality in peripheral nerve projection. Neuron 1997, 19:519-530.
    • (1997) Neuron , vol.19 , pp. 519-530
    • Taniguchi, M.1    Yuasa, S.2    Fujisawa, H.3    Naruse, I.4    Saga, S.5    Mishina, M.6
  • 52
    • 34250662228 scopus 로고    scopus 로고
    • Selective requirements for NRP1 ligands during neurovascular patterning
    • Vieira J.M., Schwarz Q., Ruhrberg C. Selective requirements for NRP1 ligands during neurovascular patterning. Development 2007, 134:1833-1843.
    • (2007) Development , vol.134 , pp. 1833-1843
    • Vieira, J.M.1    Schwarz, Q.2    Ruhrberg, C.3
  • 54
    • 0036333789 scopus 로고    scopus 로고
    • Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system
    • Kawasaki T., Bekku Y., Suto F., Kitsukawa T., Taniguchi M., Nagatsu I., et al. Requirement of neuropilin 1-mediated Sema3A signals in patterning of the sympathetic nervous system. Development 2002, 129:671-680.
    • (2002) Development , vol.129 , pp. 671-680
    • Kawasaki, T.1    Bekku, Y.2    Suto, F.3    Kitsukawa, T.4    Taniguchi, M.5    Nagatsu, I.6
  • 55
    • 0034023548 scopus 로고    scopus 로고
    • Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections
    • Chen H., Bagri A., Zupicich J.A., Zou Y., Stoeckli E., Pleasure S.J., et al. Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections. Neuron 2000, 25:43-56.
    • (2000) Neuron , vol.25 , pp. 43-56
    • Chen, H.1    Bagri, A.2    Zupicich, J.A.3    Zou, Y.4    Stoeckli, E.5    Pleasure, S.J.6
  • 56
    • 29144461035 scopus 로고    scopus 로고
    • Distinct roles for secreted semaphorin signaling in spinal motor axon guidance
    • Huber A.B., Kania A., Tran T.S., Gu C., De Marco Garcia N., Lieberam I., et al. Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron 2005, 48:949-964.
    • (2005) Neuron , vol.48 , pp. 949-964
    • Huber, A.B.1    Kania, A.2    Tran, T.S.3    Gu, C.4    De Marco Garcia, N.5    Lieberam, I.6
  • 57
    • 0032483979 scopus 로고    scopus 로고
    • Patterning of cortical efferent projections by semaphorin-neuropilin interactions
    • Polleux F., Giger R.J., Ginty D.D., Kolodkin A.L., Ghosh A. Patterning of cortical efferent projections by semaphorin-neuropilin interactions. Science 1998, 282:1904-1906.
    • (1998) Science , vol.282 , pp. 1904-1906
    • Polleux, F.1    Giger, R.J.2    Ginty, D.D.3    Kolodkin, A.L.4    Ghosh, A.5
  • 58
    • 84872066036 scopus 로고    scopus 로고
    • Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity
    • Tillo M., Ruhrberg C., Mackenzie F. Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity. Cell Adhesion & Migration 2012, 6:541-546.
    • (2012) Cell Adhesion & Migration , vol.6 , pp. 541-546
    • Tillo, M.1    Ruhrberg, C.2    Mackenzie, F.3
  • 59
    • 4344594556 scopus 로고    scopus 로고
    • PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development
    • Gitler A.D., Lu M.M., Epstein J.A. PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development. Developmental Cell 2004, 7:107-116.
    • (2004) Developmental Cell , vol.7 , pp. 107-116
    • Gitler, A.D.1    Lu, M.M.2    Epstein, J.A.3
  • 60
    • 36549056078 scopus 로고    scopus 로고
    • Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
    • Appleton B.A., Wu P., Maloney J., Yin J., Liang W.C., Stawicki S., et al. Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. The EMBO Journal 2007, 26:4902-4912.
    • (2007) The EMBO Journal , vol.26 , pp. 4902-4912
    • Appleton, B.A.1    Wu, P.2    Maloney, J.3    Yin, J.4    Liang, W.C.5    Stawicki, S.6
  • 61
    • 19944430075 scopus 로고    scopus 로고
    • Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins
    • Gu C., Yoshida Y., Livet J., Reimert D.V., Mann F., Merte J., et al. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science 2005, 307:265-268.
    • (2005) Science , vol.307 , pp. 265-268
    • Gu, C.1    Yoshida, Y.2    Livet, J.3    Reimert, D.V.4    Mann, F.5    Merte, J.6
  • 62
    • 41949129114 scopus 로고    scopus 로고
    • Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor
    • Acevedo L.M., Barillas S., Weis S.M., Gothert J.R., Cheresh D.A. Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor. Blood 2008, 111:2674-2680.
    • (2008) Blood , vol.111 , pp. 2674-2680
    • Acevedo, L.M.1    Barillas, S.2    Weis, S.M.3    Gothert, J.R.4    Cheresh, D.A.5
  • 63
    • 45749092525 scopus 로고    scopus 로고
    • Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice
    • Zacchigna S., Pattarini L., Zentilin L., Moimas S., Carrer A., Sinigaglia M., et al. Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice. The Journal of Clinical Investigation 2008, 118:2062-2075.
    • (2008) The Journal of Clinical Investigation , vol.118 , pp. 2062-2075
    • Zacchigna, S.1    Pattarini, L.2    Zentilin, L.3    Moimas, S.4    Carrer, A.5    Sinigaglia, M.6
  • 65
    • 49049093981 scopus 로고    scopus 로고
    • Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells
    • Toyofuku T., Yoshida J., Sugimoto T., Yamamoto M., Makino N., Takamatsu H., et al. Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells. Developmental Biology 2008, 321:251-262.
    • (2008) Developmental Biology , vol.321 , pp. 251-262
    • Toyofuku, T.1    Yoshida, J.2    Sugimoto, T.3    Yamamoto, M.4    Makino, N.5    Takamatsu, H.6
  • 66
    • 0034839802 scopus 로고    scopus 로고
    • Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption
    • Feiner L., Webber A.L., Brown C.B., Lu M.M., Jia L., Feinstein P., et al. Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. Development 2001, 128:3061-3070.
    • (2001) Development , vol.128 , pp. 3061-3070
    • Feiner, L.1    Webber, A.L.2    Brown, C.B.3    Lu, M.M.4    Jia, L.5    Feinstein, P.6
  • 67
    • 0034845561 scopus 로고    scopus 로고
    • PlexinA2 and semaphorin signaling during cardiac neural crest development
    • Brown C.B., Feiner L., Lu M.M., Li J., Ma X., Webber A.L., et al. PlexinA2 and semaphorin signaling during cardiac neural crest development. Development 2001, 128:3071-3080.
    • (2001) Development , vol.128 , pp. 3071-3080
    • Brown, C.B.1    Feiner, L.2    Lu, M.M.3    Li, J.4    Ma, X.5    Webber, A.L.6
  • 69
    • 78649845288 scopus 로고    scopus 로고
    • In the beginning: generating neural crest cell diversity
    • Ruhrberg C., Schwarz Q. In the beginning: generating neural crest cell diversity. Cell Adhesion & Migration 2010, 4:622-630.
    • (2010) Cell Adhesion & Migration , vol.4 , pp. 622-630
    • Ruhrberg, C.1    Schwarz, Q.2
  • 71
    • 34548618191 scopus 로고    scopus 로고
    • Neuropilin 2/semaphorin 3F signaling is essential for cranial neural crest migration and trigeminal ganglion condensation
    • Gammill L.S., Gonzalez C., Bronner-Fraser M. Neuropilin 2/semaphorin 3F signaling is essential for cranial neural crest migration and trigeminal ganglion condensation. Developmental Neurobiology 2007, 67:47-56.
    • (2007) Developmental Neurobiology , vol.67 , pp. 47-56
    • Gammill, L.S.1    Gonzalez, C.2    Bronner-Fraser, M.3
  • 72
    • 31644433604 scopus 로고    scopus 로고
    • Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling
    • Gammill L.S., Gonzalez C., Gu C., Bronner-Fraser M. Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development 2006, 133:99-106.
    • (2006) Development , vol.133 , pp. 99-106
    • Gammill, L.S.1    Gonzalez, C.2    Gu, C.3    Bronner-Fraser, M.4
  • 73
    • 84865181852 scopus 로고    scopus 로고
    • NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system
    • Maden C.H., Gomes J., Schwarz Q., Davidson K., Tinker A., Ruhrberg C. NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. Developmental Biology 2012, 369:277-285.
    • (2012) Developmental Biology , vol.369 , pp. 277-285
    • Maden, C.H.1    Gomes, J.2    Schwarz, Q.3    Davidson, K.4    Tinker, A.5    Ruhrberg, C.6
  • 74
    • 46049109310 scopus 로고    scopus 로고
    • Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells
    • Schwarz Q., Vieira J.M., Howard B., Eickholt B.J., Ruhrberg C. Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells. Development 2008, 135:1605-1613.
    • (2008) Development , vol.135 , pp. 1605-1613
    • Schwarz, Q.1    Vieira, J.M.2    Howard, B.3    Eickholt, B.J.4    Ruhrberg, C.5
  • 75
    • 69549088759 scopus 로고    scopus 로고
    • Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia
    • Schwarz Q., Maden C.H., Davidson K., Ruhrberg C. Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia. Development 2009, 136:1785-1789.
    • (2009) Development , vol.136 , pp. 1785-1789
    • Schwarz, Q.1    Maden, C.H.2    Davidson, K.3    Ruhrberg, C.4
  • 76
    • 69549138637 scopus 로고    scopus 로고
    • Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation
    • Roffers-Agarwal J., Gammill L.S. Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation. Development 2009, 136:1879-1888.
    • (2009) Development , vol.136 , pp. 1879-1888
    • Roffers-Agarwal, J.1    Gammill, L.S.2
  • 77
    • 40149111677 scopus 로고    scopus 로고
    • Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors
    • Waimey K.E., Huang P.H., Chen M., Cheng H.J. Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors. Developmental Biology 2008, 315:448-458.
    • (2008) Developmental Biology , vol.315 , pp. 448-458
    • Waimey, K.E.1    Huang, P.H.2    Chen, M.3    Cheng, H.J.4
  • 78
    • 84868616455 scopus 로고    scopus 로고
    • Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity
    • Prud'homme G.J., Glinka Y. Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity. Oncotarget 2012.
    • (2012) Oncotarget
    • Prud'homme, G.J.1    Glinka, Y.2
  • 80
    • 76749152925 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells
    • Zhang S., Zhau H.E., Osunkoya A.O., Iqbal S., Yang X., Fan S., et al. Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells. Molecular Cancer 2010, 9:9.
    • (2010) Molecular Cancer , vol.9 , pp. 9
    • Zhang, S.1    Zhau, H.E.2    Osunkoya, A.O.3    Iqbal, S.4    Yang, X.5    Fan, S.6
  • 81
    • 41049086388 scopus 로고    scopus 로고
    • Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity
    • Sulpice E., Plouet J., Berge M., Allanic D., Tobelem G., Merkulova-Rainon T. Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity. Blood 2008, 111:2036-2045.
    • (2008) Blood , vol.111 , pp. 2036-2045
    • Sulpice, E.1    Plouet, J.2    Berge, M.3    Allanic, D.4    Tobelem, G.5    Merkulova-Rainon, T.6
  • 82
    • 46949088806 scopus 로고    scopus 로고
    • Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity
    • Glinka Y., Prud'homme G.J. Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity. Journal of Leukocyte Biology 2008, 84:302-310.
    • (2008) Journal of Leukocyte Biology , vol.84 , pp. 302-310
    • Glinka, Y.1    Prud'homme, G.J.2
  • 83
    • 79953702245 scopus 로고    scopus 로고
    • Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta
    • Glinka Y., Stoilova S., Mohammed N., Prud'homme G.J. Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta. Carcinogenesis 2011, 32:613-621.
    • (2011) Carcinogenesis , vol.32 , pp. 613-621
    • Glinka, Y.1    Stoilova, S.2    Mohammed, N.3    Prud'homme, G.J.4
  • 84
    • 35948965519 scopus 로고    scopus 로고
    • Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion
    • Fukasawa M., Matsushita A., Korc M. Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion. Cancer Biology and Therapy 2007, 6:1173-1180.
    • (2007) Cancer Biology and Therapy , vol.6 , pp. 1173-1180
    • Fukasawa, M.1    Matsushita, A.2    Korc, M.3
  • 85
    • 0041530325 scopus 로고    scopus 로고
    • Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
    • Serini G., Valdembri D., Zanivan S., Morterra G., Burkhardt C., Caccavari F., et al. Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 2003, 424:391-397.
    • (2003) Nature , vol.424 , pp. 391-397
    • Serini, G.1    Valdembri, D.2    Zanivan, S.3    Morterra, G.4    Burkhardt, C.5    Caccavari, F.6
  • 86
    • 58849090461 scopus 로고    scopus 로고
    • Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells
    • Valdembri D., Caswell P.T., Anderson K.I., Schwarz J.P., Konig I., Astanina E., et al. Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biology 2009, 7:e25.
    • (2009) PLoS Biology , vol.7
    • Valdembri, D.1    Caswell, P.T.2    Anderson, K.I.3    Schwarz, J.P.4    Konig, I.5    Astanina, E.6
  • 87
    • 14944344614 scopus 로고    scopus 로고
    • Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2
    • Murga M., Fernandez-Capetillo O., Tosato G. Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2. Blood 2005, 105:1992-1999.
    • (2005) Blood , vol.105 , pp. 1992-1999
    • Murga, M.1    Fernandez-Capetillo, O.2    Tosato, G.3
  • 91
    • 84865140752 scopus 로고    scopus 로고
    • Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment
    • Yaqoob U., Cao S., Shergill U., Jagavelu K., Geng Z., Yin M., et al. Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment. Cancer Research 2012, 72:4047-4059.
    • (2012) Cancer Research , vol.72 , pp. 4047-4059
    • Yaqoob, U.1    Cao, S.2    Shergill, U.3    Jagavelu, K.4    Geng, Z.5    Yin, M.6
  • 92
    • 0033674846 scopus 로고    scopus 로고
    • Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression
    • Miao H.Q., Lee P., Lin H., Soker S., Klagsbrun M. Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression. FASEB Journal 2000, 14:2532-2539.
    • (2000) FASEB Journal , vol.14 , pp. 2532-2539
    • Miao, H.Q.1    Lee, P.2    Lin, H.3    Soker, S.4    Klagsbrun, M.5
  • 95
    • 0141816865 scopus 로고    scopus 로고
    • Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells
    • Bachelder R.E., Lipscomb E.A., Lin X., Wendt M.A., Chadborn N.H., Eickholt B.J., et al. Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Research 2003, 63:5230-5233.
    • (2003) Cancer Research , vol.63 , pp. 5230-5233
    • Bachelder, R.E.1    Lipscomb, E.A.2    Lin, X.3    Wendt, M.A.4    Chadborn, N.H.5    Eickholt, B.J.6
  • 96
    • 84865137629 scopus 로고    scopus 로고
    • Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer
    • Tamagnone L. Emerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancer. Cancer Cell 2012, 22:145-152.
    • (2012) Cancer Cell , vol.22 , pp. 145-152
    • Tamagnone, L.1
  • 98
    • 70349973901 scopus 로고    scopus 로고
    • Autocrine semaphorin 3A signaling promotes glioblastoma dispersal
    • Bagci T., Wu J.K., Pfannl R., Ilag L.L., Jay D.G. Autocrine semaphorin 3A signaling promotes glioblastoma dispersal. Oncogene 2009, 28:3537-3550.
    • (2009) Oncogene , vol.28 , pp. 3537-3550
    • Bagci, T.1    Wu, J.K.2    Pfannl, R.3    Ilag, L.L.4    Jay, D.G.5
  • 99
    • 70449428715 scopus 로고    scopus 로고
    • Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models
    • Maione F., Molla F., Meda C., Latini R., Zentilin L., Giacca M., et al. Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. Journal of Clinical Investigation 2009, 119:3356-3372.
    • (2009) Journal of Clinical Investigation , vol.119 , pp. 3356-3372
    • Maione, F.1    Molla, F.2    Meda, C.3    Latini, R.4    Zentilin, L.5    Giacca, M.6
  • 100
    • 84875628911 scopus 로고    scopus 로고
    • Expression of semaphorin 3F and its receptors in epithelial ovarian cancer, fallopian tubes, and secondary mullerian tissues
    • Drenberg C.D., Livingston S., Chen R., Kruk P.A., Nicosia S.V. Expression of semaphorin 3F and its receptors in epithelial ovarian cancer, fallopian tubes, and secondary mullerian tissues. Obstetrics and Gynecology International 2009, 2009:730739.
    • (2009) Obstetrics and Gynecology International , vol.2009 , pp. 730739
    • Drenberg, C.D.1    Livingston, S.2    Chen, R.3    Kruk, P.A.4    Nicosia, S.V.5
  • 101
    • 76649115312 scopus 로고    scopus 로고
    • Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer
    • Joseph D., Ho S.M., Syed V. Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer. Molecular Cancer Therapeutics 2010, 9:499-509.
    • (2010) Molecular Cancer Therapeutics , vol.9 , pp. 499-509
    • Joseph, D.1    Ho, S.M.2    Syed, V.3
  • 102
    • 0033874073 scopus 로고    scopus 로고
    • Semaphorin SEMA3F localization in malignant human lung and cell lines: a suggested role in cell adhesion and cell migration
    • Brambilla E., Constantin B., Drabkin H., Roche J. Semaphorin SEMA3F localization in malignant human lung and cell lines: a suggested role in cell adhesion and cell migration. The American Journal of Pathology 2000, 156:939-950.
    • (2000) The American Journal of Pathology , vol.156 , pp. 939-950
    • Brambilla, E.1    Constantin, B.2    Drabkin, H.3    Roche, J.4
  • 103
    • 33847766123 scopus 로고    scopus 로고
    • Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21.3, in p53-regulated tumor angiogenesis suppression
    • Futamura M., Kamino H., Miyamoto Y., Kitamura N., Nakamura Y., Ohnishi S., et al. Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21.3, in p53-regulated tumor angiogenesis suppression. Cancer Research 2007, 67:1451-1460.
    • (2007) Cancer Research , vol.67 , pp. 1451-1460
    • Futamura, M.1    Kamino, H.2    Miyamoto, Y.3    Kitamura, N.4    Nakamura, Y.5    Ohnishi, S.6
  • 105
    • 85047693077 scopus 로고    scopus 로고
    • Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype
    • Bielenberg D.R., Hida Y., Shimizu A., Kaipainen A., Kreuter M., Kim C.C., et al. Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype. The Journal of Clinical Investigation 2004, 114:1260-1271.
    • (2004) The Journal of Clinical Investigation , vol.114 , pp. 1260-1271
    • Bielenberg, D.R.1    Hida, Y.2    Shimizu, A.3    Kaipainen, A.4    Kreuter, M.5    Kim, C.C.6
  • 106
    • 85046979809 scopus 로고    scopus 로고
    • Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2
    • Coma S., Shimizu A., Klagsbrun M. Hypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2. Cell Adhesion & Migration 2011, 5:266-275.
    • (2011) Cell Adhesion & Migration , vol.5 , pp. 266-275
    • Coma, S.1    Shimizu, A.2    Klagsbrun, M.3
  • 107
    • 20344381552 scopus 로고    scopus 로고
    • Selective suppression of in vivo tumorigenicity by semaphorin SEMA3F in lung cancer cells
    • Kusy S., Nasarre P., Chan D., Potiron V., Meyronet D., Gemmill R.M., et al. Selective suppression of in vivo tumorigenicity by semaphorin SEMA3F in lung cancer cells. Neoplasia 2005, 7:457-465.
    • (2005) Neoplasia , vol.7 , pp. 457-465
    • Kusy, S.1    Nasarre, P.2    Chan, D.3    Potiron, V.4    Meyronet, D.5    Gemmill, R.M.6
  • 109
    • 33845991161 scopus 로고    scopus 로고
    • Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth
    • Pan Q., Chanthery Y., Liang W.C., Stawicki S., Mak J., Rathore N., et al. Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell 2007, 11:53-67.
    • (2007) Cancer Cell , vol.11 , pp. 53-67
    • Pan, Q.1    Chanthery, Y.2    Liang, W.C.3    Stawicki, S.4    Mak, J.5    Rathore, N.6


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