A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability

Journal of Biological Chemistry

Volumn 274, Issue 49, 1999, Pages 34884-34892

  Stacker, Steven A ^b   Vitali, Angela ^b   Caesar, Carol ^b   Domagala, Teresa ^b   Groenen, Leo C ^b   Nice, Edouard ^b   Achen, Marc G ^b   Wilks, Andrew F ^a  

^a ST VINCENT S HOSPITAL   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CONFORMATIONAL TRANSITION; GENE MUTATION; GROWTH REGULATION; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN DETERMINATION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

EID: 0033520916     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.49.34884     Document Type: Article

References (56)

1. Carmeliet, P., Ferreira, V., Breier, G., Pollofeyt, S., Keickens, L., Gertenstein, M., Fahrig, M., Vandenhoeck, A., Harpal, K., Eberhardt, C., Declerq, C., Pawling, J., Moons, L., Collen, D., Risau, W., and Nagy, A. (1996) Nature 380, 435-439
2. Ferrara, N., Carver-Moore, K., Chen, H., Dowd, M., Lu, L., O'Shea, K. S., Powel-Braxton, L., Hillan, K. J., and Moore, M. W. (1996) Nature 380, 439-443
3. Plate, K. H., Breier, G., Weich, H. A., and Risau, W. (1992) Nature 359, 845-848
4. Stacker, S. A., and Achen, M. G. (1999) Growth Factors 17, 1-11
5. Senger, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S., and Dvorak, H. F. (1983) Science 219, 983-985
6. Yeo, K. T., Wang, H. H., Nagy, J. A., Sioussat, T. M., Ledbetter, S. R, Hoogewerf, A. J., Zhou, Y., Masse, E. M., Senger, D. R., Dvorak, H. F., and Yeo, T. K. (1993) Cancer Res. 53, 2912-2918
7. McDonald, N. Q., and Hendrickson, W. A. (1993) Cell 73, 421-424
8. Leung, D. W., Cachianes, G., Kuang, W. J., Goeddel, D. V., and Ferrara, N. (1989) Science 246, 1306-1309
9. Houck, K. A., Ferrara, N., Winer, J., Cachianes, G., Li, B., and Leung, D. W. (1991) Mol. Endocrinol. 5, 1806-1814
10. Tischer, E., Mitchell, R., Hartman, T., Silva, M., Gospodarowicz, D., Fiddes, J. C., and Abraham, J. A. (1991) J. Biol. Chem. 266, 11947-11954
11. Poltorak, Z., Cohen, T., Sivan, R., Kandelis, Y., Spira, G., Vlodavsky, I., Keshet, E., and Neufeld, G. (1997) J. Biol. Chem. 272, 7151-7158
12. Olofsson, B., Pajusola, K., Kaipainen, A., von Euler, G., Joukov, V., Saksela, O., Orpana, A., Pettersson, R. F., Alitalo, K., and Eriksson, U. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2576-2581
13. Joukov, V., Pajusola, K., Kaipainen, A., Chilov, D., Lahtinen, I., Kukk, E., Saksela, O., Kalkkinen, N., and Alitalo, K. (1996) EMBO J. 15, 290-298
14. Achen, M. G., Jeltsch, M., Kukk, E., Mäkinen, T., Vitali, A., Wilks, A. F., Alitalo, K., and Stacker, S. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 96, 548-553
15. Maglione, D., Guerriero, V., Viglietto, G., Delli Bovi, P., and Persico, M. G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 9267-9271
16. Damert, A., Machein, M., Breier, G., Fujita, M. Q., Hanahan, D., Risau, W., and Plate, K. H. (1997) Cancer Res. 57, 3860-3864
17. Terman, B. I., Dougher Vermazen, M., Carrion, M. E., Dimitrov, D., Armellino, D. C., Gospodarowicz, D., and Bohlen, P. (1992) Biochem. Biophys. Res. Commun. 187, 1579-1586
18. Millauer, B., Wizigmann-Voos, S., Schnürch, H., Martinez, R., Moller, N. P. H., Risau, W., and Ullrich, A. (1993) Cell 72, 835-846
19. Quinn, T. P., Peters, K. G., De Vries, C., Ferrara, N., and Williams, L. T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 7533-7537
20. Waltenberger, J., Claesson-Welsh, L., Siegbahn, A., Shibuya, M., and Heldin, C. H. (1994) J. Biol. Chem. 269, 26988-26995
21. Seetharam, L., Gotoh, N., Maru, Y., Neufeld, G., Yamaguchi, S., and Shibuya, M. (1995) Oncogene 10, 135-147
22. Shalaby, F., Rossant, J., Yamaguchi, T. P., Gertsenstein, M., Wu, X. F., Breitman, M. L., and Schuh, A. C. (1995) Nature 376, 62-66
23. Fong, G.-H., Rossant, J., Gertsenstein, M., and Breitman, M. L. (1995) Nature 378, 66-70
24. Soker, S., Takashima, S., Miao, H. Q., Neufeld, G., and Klagsbrun, M. (1998) Cell 92, 735-745
25. Murohara, T., Horowitz, J. R., Silver, M., Tsurumi, Y., Chen, D., Sullivan, A., and Isner, J. M. (1998) Circulation 97, 99-107
26. Parenti, A., Morbidelli, L., Cui, X. L., Douglas, J. G., Hood, J. D., Granger, H. J., Ledda, F., and Ziche, M. (1998) J. Biol. Chem. 273, 4220-4226
27. Joukov, V., Kumar, V., Sorsa, T., Arighi, E., Weich, H., Saksela, O., and Alitalo, K. (1998) J. Biol. Chem. 273, 6599-6602
28. Dvorak, H. F., Orenstein, N. S., Carvalho, A. C., Churchill, W. H., Dvorak, A. M., Galli, S. J., Feder, J., Bitzer, A. M., Rypysc, J., and Giovinco, P. (1979) J. Immunol. 122, 166-174
29. Kohn, S., Nagy, J. A., Dvorak, H. F., and Dvorak, A. M. (1992) Lab. Invest. 67, 596-607
30. Feng, D., Nagy, J. A., Hipp, J., Dvorak, H. F., and Dvorak, A. M. (1996) J. Exp. Med. 183, 1981-1986
31. Kevil, C. G., Payne, D. K., Mire, E., and Alexander, J. S. (1998) J. Biol. Chem. 273, 15099-15103
32. Antonetti, D. A., Barber, A. J., Hollinger, L. A., Wolpert, E. B., and Gardner, T. W. (1999) J. Biol. Chem. 274, 23463-23467
33. Koblizek, T. I., Runting, A. S., Stacker, S. A., Wilks, A. F., Risau, W., and Deutsch, U. (1997) Eur. J. Biochem. 244, 774-779
34. Aruffo, A., and Seed, B. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 8573-8577
35. Stacker, S. A., and Springer, T. A. (1991) J. Immunol. 146, 648-655
36. Laemmli, U. K. (1970) Nature 227, 680-685
37. Breier, G., Albrecht, U., Sterrer, S., and Risau, W. (1992) Development 114, 521-532
38. Miles, A. A., and Miles, E. M. (1952) J. Physiol. (Lond.) 118, 228-257
39. Oelrichs, R. B., Reid, H. H., Bernard, O., Ziemiecki, A., and Wilks, A. F. (1993) Oncogene 8, 11-18
40. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 488-492
41. Kabrun, N., Bühring, H.-J., Choi, K., Ullrich, A., Risau, W., and Keller, G. (1997) Development 124, 2039-2048
42. Nice, E., Lackmann, M., Smyth, F., Fabri, L., and Burgess, A. W. (1994) J. Chromatogr. A 660, 169-185
43. Stacker, S. A., Stenvers, K., Caesar, C., Vitali, A., Domagala, T., Nice, E., Roufail, S., Moritz, R., Simpson, R. J., Alitalo, K., Karpanen, T., and Achen, M. G. (1999) J. Biol. Chem. 274, 32127-32136
44. Wise, L. M., Veikkola, T., Mercer, A. A., Savory, L. J., Fleming, S. B., Caesar, C., Vitali, A., Makinen, T., Alitalo, K., and Stacker, S. A. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3071-3076
45. Ostman, A., Andersson, M., Hellman, U., and Heldin, C. H. (1991) J. Biol. Chem. 266, 10073-10077
46. Vassbotn, F. S., Andersson, M., Westermark, B., Heldin, C. H., and Ostman, A. (1993) Mol. Cell. Biol. 13, 4066-4076
47. Pacifici, R. E., and Thomason, A. R. (1994) J. Biol. Chem. 269, 1571-1574
48. Keyt, B. A., Nguyen, H. V., Berleau, L. T., Duarte, C. M., Park, J., Chen, H., and Ferrara, N. (1996) J. Biol. Chem. 271, 5638-5646
49. Siemeister, G., Schirner, M., Reusch, P., Barleon, B., Marmé, D., and Martiny-Baron, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4625-4629
50. Muller, Y. A., Li, B., Christinger, H. W., Wells, J. A., Cunningham, B. C., and de Vos, A. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7192-7197
51. Dvorak, A. M., Kohn, S., Morgan, E. S., Fox, P., Nagy, J. A., and Dvorak, H. F. (1996). J. Leukocyte Biol. 59, 100-115
52. Millauer, B., Wizigmann-Voos, S., Schnürch, H., Martinez, R., Moller, N. P. H., Risau, W., and Ullrich, A. (1993) Cell 72, 835-846
53. Ferrara, N., and Keyt, B. A. (1997) in Regulation of Angiogenesis (Goldberg, I. D., and Rosen, E. M., eds) pp. 209-232, Birkhasuser Verlag, Basel
54. Ogawa, S., Oku, A., Sawano, A., Yamaguchi, S., Yazaki, Y., and Shibuya, M. (1998) J. Biol. Chem. 273, 31273-31282
55. Gitay-Goren, H., Cohen, T., Tessler, S., Soker, S., Gengrinovitch, S., Rockwell, P., Klagsburn, M., Levi, B.-Z., and Neufeld, G. (1996) J. Biol. Chem. 271, 5519-5523
56. Achen, M. G., Gad, J. M., Stacker, S. A., and Wilks, A. F. (1997) Growth Factors 15, 69-80