Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state

Development

Volumn 127, Issue 7, 2000, Pages 1445-1453

  Haigh, Jody J ^a   Gerber, Hans Peter ^b   Ferrara, Napoleone ^b   Wagner, Erwin F ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^b GENENTECH INC   (United States)

Author keywords

Angiogenesis; Cardiomyopathy; Cartilage; Collagen2al; Conditional gene targeting; Cre loxP; Heart development; Vascular endothelial growth factor (VEGF)

Indexed keywords

COLLAGEN TYPE 2; MESSENGER RNA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL; CARDIOMYOPATHY; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; ENCHONDRAL OSSIFICATION; ENDOCARDIUM; FETUS; GENE DELETION; HEART DEVELOPMENT; HEART MUSCLE; ISCHEMIC HEART DISEASE; LIMB BUD; MESENCHYME; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SCLEROTOME; SOMITE; TRANSGENIC MOUSE;

ANIMALS; BONE DEVELOPMENT; CHONDROGENESIS; COLLAGEN; ENDOTHELIAL GROWTH FACTORS; FETAL DEATH; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; HEART; HETEROZYGOTE; IN SITU HYBRIDIZATION; LAC OPERON; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; MUS MUSCULUS;

EID: 0034097594     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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