The role of cognitive processes in vestibular disorders

Hearing, Balance and Communication

Volumn 11, Issue SUPPL. 1, 2013, Pages 3-35

  Guidetti, Giorgio ^a  

^a Ramazzini Hospital   (Italy)

Author keywords

Cognition; Vertigo; Vertigo therapy; Vestibular system

Indexed keywords

ANTIHISTAMINIC AGENT; BENZODIAZEPINE; BETAHISTINE; BRAIN DERIVED NEUROTROPHIC FACTOR; FLUORODEOXYGLUCOSE F 18; GINKGO BILOBA EXTRACT; GLUTAMINE; GLYCINE; NOOTROPIC AGENT; NORADRENALIN; PIRACETAM; STEROID; TAURINE; THREONINE;

ADAPTATION; ALZHEIMER DISEASE; AMNESIA; AMYGDALOID NUCLEUS; ANTICHOLINERGIC EFFECT; ANXIETY; ARTICLE; BALANCE DISORDER; BASAL GANGLION; BEHAVIOR THERAPY; BODY EQUILIBRIUM; BRAIN CORTEX; BRAIN FORNIX; CAUDATE NUCLEUS; CENTRAL NERVOUS SYSTEM; CEREBELLUM; CINGULATE GYRUS; COGNITION; DENTATE GYRUS; DEPRESSION; DEPTH PERCEPTION; DISABILITY; DIZZINESS; EMOTIONAL DISORDER; EMOTIONAL STRESS; ENVIRONMENTAL STRESS; EVOKED SOMATOSENSORY RESPONSE; FEAR; FRONTAL EYE FIELD; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENICULATE NUCLEUS; GLUCOSE METABOLISM; HEMISPHERE; HEMISPHERIC DOMINANCE; HIPPOCAMPUS; HUMAN; HYPNOSIS; HYPOTHALAMUS; INFERIOR FRONTAL GYRUS; INFERIOR PARIETAL LOBULE; LEFT HANDEDNESS; LIMBIC SYSTEM; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MEMORY DISORDER; MIDDLE FRONTAL GYRUS; MILD COGNITIVE IMPAIRMENT; NEUROIMAGING; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; NYSTAGMUS; OLFACTORY BULB; PANIC; PARAHIPPOCAMPAL GYRUS; PARIETAL OPERCULUM; PATIENT COUNSELING; PLASTICITY; POLYSYNAPTIC REFLEX; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PREMOTOR CORTEX; PRIMARY MOTOR CORTEX; PRIMARY SOMATOSENSORY CORTEX; PRIORITY JOURNAL; PROPRIOCEPTION; PULVINAR; REACTION TIME; RIGHT HANDEDNESS; SACCADIC EYE MOVEMENT; SELECTIVE ATTENTION; SPATIAL LEARNING; SUPERIOR FRONTAL GYRUS; SUPERIOR PARIETAL LOBULE; THALAMUS POSTERIOR NUCLEUS; VESTIBULAR DISORDER; VESTIBULAR NERVE; VESTIBULAR STIMULATION; VESTIBULAR SYSTEM; VISUAL CORTEX; VISUAL INFORMATION; VISUAL MEMORY; WORKING MEMORY;

EID: 84875480603     PISSN: 21695717     EISSN: 21695725     Source Type: Journal    
DOI: 10.3109/21695717.2013.765085     Document Type: Article

References (441)

1. Bense S, Stephan T, Yousry TA, Brandt T, Dieterich M. Multisensory cortical signal increases and decreases during vestibular galvanic stimulation (fMRI). J Neurophysiol. 2001;85:886-99.
2. Aguirre GK, D'Esposito M. Topographical disorientation: a synthesis and taxonomy. Brain. 1999;122:1613-28.
3. Hanes DA, McCollum G. Cognitive-vestibular interactions: a review of patient difficulties and possible mechanisms. J Vestib Res. 2006;16:75-91.
4. Marcelli V, Esposito F, Aragri A, Furia T, Riccardi P, Tosetti M, et al. Spatio-temporal pattern of vestibular information processing after brief caloric stimulation. Eur J Radiol. 2009;70:312-6.
5. Schmahmann JD. The cerebellum and cognition . Int Rev Neurobiol. 1997;41:151-339.
6. Houck JM, Martin T, Bish JP, Moses SN, Woodruff CC, Kicic D, et al. Early cerebellar activation predicts response time. International Congress Series. 2007;1300:413-6.
7. O'Reilly JX, Mesulam MM, Nobre AC. The cerebellum predicts the timing of perceptual events. J Neurosci. 2008; 28:2252-60.
8. Mauk MD, Medina JF, Nores WL, Ohyama T. Cerebellar function: coordination, learning or timing? Curr Biol. 2000;10:R522-5.
9. Aso K, Hanakawa T, Aso T, Fukuyama H. Cerebro-cerebellar interactions underlying temporal information processing. J Cogn Neurosci. 2010;22:2913-25.
10. Koziol LF, Budding DE, Chidekel D. Adaptation, expertise, and giftedness: towards an understanding of cortical, subcortical, and cerebellar network contributions. Cerebellum. 2010;9:499-529.
11. Salmi J, Pallesen KJ, Neuvonen T, Brattico E, Korvenoja A, Salonen O, et al. Cognitive and motor loops of the human cerebro-cerebellar system. J Cogn Neurosci. 2010; 22:2663-76.
12. Porrill J, Dean P. Cerebellar motor learning: when is cortical plasticity not enough? PLoS Comput Biol. 2007;3:1935-50.
13. Broussard DM, Kassardjian CD. Learning in a simple motor system. Learn Mem. 2004;11:127-36.
14. Salman MS. The cerebellum: it's about time! But timing is not everything: new insights into the role of the cerebellum in timing motor and cognitive tasks. J Child Neurol. 2002; 17:1-9.
15. Stoodley CJ, Schmahmann JD. Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. Neuroimage. 2009;44:489-501.
16. Baillieux H, de Smet HJ, Paquier PF, de Deyn PP, Marien P. Cerebellar neurocognition: insights into the bottom of the brain . Clin Neurol Neurosurg. 2008;110:763-73.
17. Okamoto T, Shirao T, Shutoh F, Suzuki T, Nagao S. Post-training cerebellar cortical activity plays an important role for consolidation of memory of cerebellum-dependent motor learning. Neurosci Lett. 2011;504:53-6.
18. Okamoto T, Endo S, Shirao T, Nagao S. Role of cerebellar cortical protein synthesis in transfer of memory trace of cerebellum-dependent motor learning. J Neurosci. 2011; 31:8958-66.
19. Blazquez PM, Hirata Y, Highstein SM. The vestibulo-ocular reflex as a model system for motor learning: what is the role of the cerebellum? Cerebellum. 2004;3:188-92.
20. Broussard DM, Titley HK, Antflick J, Hampson DR. Motor learning in the VOR: the cerebellar component. Exp Brain Res. 2011;210:451-63.
21. Apps R, Garwicz M. Anatomical and physiological foundations of cerebellar information processing. Nat Rev Neurosci. 2005;6:297-311.
22. Nagao S, Kitazawa H. Role of the cerebellum in the acquisition and consolidation of motor memory. Brain Nerve. 2008;60:783-90.
23. Schmahmann JD. Dysmetria of thought: clinical consequences of cerebellar dysfunction on cognition and affect. Trends Cogn Sci. 1998;2:362-71.
24. Andreasen NC, Nopoulos P, O'Leary DS, Miller DD, Wassink T, Flaum M. Defining the phenotype of schizophrenia: cognitive dysmetria and its neural mechanisms. Biol Psychiatry. 1999;46:908-20.
25. Penn HE. Neurobiological correlates of autism: a review of recent research. Child Neuropsychol. 2006;12:57-79.
26. Picard H, Amado I, Mouchet-Mages S, Olie JP, Krebs MO. The role of the cerebellum in schizophrenia: an update of clinical, cognitive, and functional evidences. Schizophr Bull. 2008;34:155-72.
27. Rosinski A, Goldman M, Cameron O. A case of cerebellar psychopathology. Psychosomatics. 2010;51:171-5.
28. Nopoulos PC, Ceilley JW, Gailis EA, Andreasen NC. An MRI study of cerebellar vermis morphology in patients with schizophrenia: evidence in support of the cognitive dys-metria concept. Biol Psychiatry. 1999;46:703-11.
29. Desmond JE, Gabrieli JD, Glover GH. Dissociation of frontal and cerebellar activity in a cognitive task: evidence for a distinction between selection and search. Neuroimage. 1998;7:368-76.
30. Fredrickson JM, Scheid P, Figge U, Kornhuber HH. Vestibular nerve projection to the cerebral cortex of the rhesus monkey. Exp Brain Res. 1966;2:318-27.
31. Pandya DN, Sanides F. Architectonic parcellation of the temporal operculum in rhesus monkey and its projection pattern. Z Anat Entwicklungsgesch. 1973;139:127-61.
32. Grusser OJ, Pause M, Schreiter U. Vestibular neurons in the parieto-insular cortex of monkeys (Macaca fascicularis): visual and neck receptor responses. J Physiol. 1990;430: 559-83.
33. Grusser OJ, Pause M, Schreiter U. Localization and responses of neurons in the parieto-insular vestibular cortex of awake monkeys (Macaca fascicularis). J Physiol. 1990; 430:537-57.
34. Liu S, Angelaki DE. Vestibular signals in macaque extrastri-ate visual cortex are functionally appropriate for heading perception. J Neurosci. 2009;29:8936-45.
35. Klam F, Graf W. Vestibular signals of posterior parietal cortex neurons during active and passive head movements in macaque monkeys. Ann N Y Acad Sci. 2003;1004:271-82.
36. Akbarian S, Grusser OJ, Guldin WO. Corticofugal connections between the cerebral cortex and brainstem vestibular nuclei in the macaque monkey. J Comp Neurol. 1994;339:421-37.
37. Bottini G, Karnath HO, Vallar G, Sterzi R, Frith CD, Frackowiak RS, et al. Cerebral representations for egocentric space: functional-anatomical evidence from caloric vestibular stimulation and neck vibration. Brain. 2001; 124:1182-96.
38. Bremmer F, Klam F, Duhamel JR, Ben HS, Graf W. Visual-vestibular interactive responses in the macaque ventral intraparietal area (VIP). Eur J Neurosci. 2002; 16:1569-86.
39. Emri M, Kisely M, Lengyel Z, Balkay L, Marian T, Miko L, et al. Cortical projection of peripheral vestibular signalling. J Neurophysiol. 2003;89:2639-6.
40. Fukushima K. Corticovestibular interactions: anatomy, elec-trophysiology, and functional considerations. Exp Brain Res. 1997;117:1-16.
41. Guldin WO, Grusser OJ. Is there a vestibular cortex? Trends Neurosci. 1998;21:254-9.
42. Klam F, Graf W. Vestibular response kinematics in posterior parietal cortex neurons of macaque monkeys. Eur J Neuro-sci. 2003;18:995-1010.
43. Schlack A, Hoffmann KP, Bremmer F. Interaction of linear vestibular and visual stimulation in the macaque ventral intraparietal area (VIP) . Eur J Neurosci. 2002;16:1877-86.
44. de Waele WC, Baudonniere PM, Lepecq JC, Tran Ba HP, Vidal PP. Vestibular projections in the human cortex. Exp Brain Res. 2001;141:541-51.
45. Ebata S, Sugiuchi Y, Izawa Y, Shinomiya K, Shinoda Y. Vestibular projection to the periarcuate cortex in the monkey. Neurosci Res. 2004;49:55-68.
46. Dieterich M, Bense S, Lutz S, Drzezga A, Stephan T, Bartenstein P, et al. Dominance for vestibular cortical function in the non-dominant hemisphere. Cereb Cortex. 2003;13:994-1007.
47. Fukushima K, Fukushima J, Warabi T. Vestibular-related frontal cortical areas and their roles in smooth-pursuit eye movements: representation of neck velocity, neck-vestibular interactions, and memory-based smooth-pursuit. Front Neurol. 2011;2:78.
48. YangY, Liu S, Chowdhury SA, DeAngelis GC, Angelaki DE. Binocular disparity tuning and visual-vestibular congruency of multisensory neurons in macaque parietal cortex. J Neurosci. 2011;31:17905-16.
49. Chen A, DeAngelis GC, Angelaki DE. Representation of vestibular and visual cues to self-motion in ventral intrapa-rietal cortex. J Neurosci. 2011;31:12036-52.
50. Chen A, DeAngelis GC, Angelaki DE. Convergence of vestibular and visual self-motion signals in an area of the posterior sylvian fissure. J Neurosci. 2011;31:11617-27.
51. Chen A, DeAngelis GC, Angelaki DE. Macaque parieto-insular vestibular cortex: responses to self-motion and optic flow. J Neurosci. 2010;30:3022-2.
52. Dieterich M, Bartenstein P, Spiegel S, Bense S, Schwaiger M, Brandt T. Thalamic infarctions cause side-specific suppression of vestibular cortex activations . Brain. 2005;128:2052-67.
53. Bottini G, Sterzi R, Paulesu E, Vallar G, Cappa SF, Erminio F, et al. Identification of the central vestibular projections in man: a positron emission tomography activation study. Exp Brain Res. 1994;99:164-9.
54. Petit L, Beauchamp MS. Neural basis of visually guided head movements studied with fMRI. J Neurophysiol. 2003;89:2516-27.
55. Bottini G, Paulesu E, Sterzi R, Warburton E, Wise RJ, Vallar G, et al. Modulation of conscious experience by peripheral sensory stimuli. Nature. 1995;376:778-81.
56. Schneider JP, Reinohs M, Prothmann S, Puccini S, Dalitz B, Schwarz J, et al. Subcortical right parietal AVM rotational vertigo and caloric stimulation fMRI support a parietal representation of vestibular input. J Neurol. 2006; 253:253-5.
57. Suzuki M, Kitano H, Ito R, Kitanishi T, Yazawa Y, Ogawa T, et al. Cortical and subcortical vestibular response to caloric stimulation detected by functional magnetic resonance imaging. Brain Res Cogn Brain Res. 2001;12:441-9.
58. Vitte E, Derosier C, Caritu Y, Berthoz A, Hasboun D, Soulie D. Activation of the hippocampal formation by ves-tibular stimulation: a functional magnetic resonance imaging study. Exp Brain Res. 1996;112:523-6.
59. Lobel E, Kleine JF, Bihan DL, Leroy-Willig A, Berthoz A. Functional MRI of galvanic vestibular stimulation. J Neuro- physiol. 1998;80:2699-709.
60. Miyamoto T, Fukushima K, Takada T, De Waele C, Vidal PP. Saccular stimulation of the human cortex: a functional magnetic resonance imaging study. Neurosci Lett. 2007; 423:68-72.
61. Bucher SF, Dieterich M, Seelos KC, Brandt T. Sensorimotor cerebral activation during optokinetic nystagmus: a functional MRI study. Neurology. 1997;49:1370-7.
62. Eickhoff SB, Weiss PH, Amunts K, Fink GR, Zilles K. Identifying human parieto-insular vestibular cortex using fMRI and cytoarchitectonic mapping. Hum Brain Mapp. 2006;27:611-21.
63. Fink GR, Marshall J C, Weiss PH, Stephan T, Grefkes C, Shah NJ, et al. Performing allocentric visuospatial judgments with induced distortion of the egocentric reference frame: an fMRI study with clinical implications. Neuroimage. 2003;20:1505-17.
64. Friberg L, Olsen TS, Roland PE, Paulson OB, Lassen NA. Focal increase of blood flow in the cerebral cortex of man during vestibular stimulation. Brain. 1985;108:609-23.
65. Hegemann S, Pawlowski M, Huonker R, Haueisen J, Fitzek C, Fetter M. Magnetoencephalography during optokinetic and vestibular activation of the posterior insula. Ann NY Acad Sci. 2003;1004:457-64.
66. Indovina I, Maffei V, Bosco G, Zago M, Macaluso E, Lacquaniti F. Representation of visual gravitational motion in the human vestibular cortex. Science. 2005; 308:416-9.
67. Naito Y, Tateya I, Hirano S, Inoue M, Funabiki K, Toyoda H, et al. Cortical correlates of vestibulo-ocular reflex modulation: a PET study. Brain. 2003;126:1562-78.
68. Schlindwein P, Mueller M, Bauermann T, Brandt T, Stoeter P, Dieterich M. Cortical representation of saccular vestibular stimulation: VEMPs in fMRI. Neuroimage. 2008; 39:19-31.
69. Stephan T, Deutschlander A, Nolte A, Schneider E, Wiesmann M, Brandt T, et al. Functional MRI of galvanic vestibular stimulation with alternating currents at different frequencies. Neuroimage. 2005;26:721-32.
70. Tuohimaa P, Aantaa E, Toukoniitty K, Makela P. Studies of vestibular cortical areas with short-living 15O2 isotopes. ORL J Otorhinolaryngol Relat Spec. 1983;45:315-21.
71. Craig AD. How do you feel - now? The anterior insula and human awareness. Nat Rev Neurosci. 2009;10:59-70.
72. Trousselard M, Barraud PA, Nougier V, Raphel C, Cian C. Contribution of tactile and interoceptive cues to the perception of the direction of gravity. Brain Res Cogn Brain Res. 2004;20:355-62.
73. Brandt T, Bartenstein P, Janek A, Dieterich M. Reciprocal inhibitory visual-vestibular interaction. Visual motion stimulation deactivates the parieto-insular vestibular cortex. Brain. 1998;121:1749-58.
74. Zu Eulenburg P, Caspers S, Roski C, Eickhoff SB. Meta-analytical definition and functional connectivity of the human vestibular cortex. Neuroimage. 2012;60: 162-9.
75. Karnath HO, Dieterich M. Spatial neglect: a vestibular disorder? Brain. 2006;129:293-305.
76. Plaschke M, Souphanthong M, Wenzel J. Morphological alterations of hippocampal pyramidal neurons heterotopi-cally transplanted into the somatosensory cortex of adult rats: a quantitative Golgi study. Anat Embryol (Berl). 1995; 192:351-61.
77. Janzen J, Schlindwein P, Bense S, Bauermann T, Vucurevic G, Stoeter P, et al. Neural correlates of hemispheric dominance and ipsilaterality within the vestibular system. Neuroimage. 2008;42:1508-18.
78. Lopez C, Blanke O, Mast FW. The human vestibular cortex revealed by coordinate-based activation likelihood estimation meta-analysis. Neuroscience. 2012;212:159-79.
79. Schlosser HG, Guldin W, Fritzsche D, Clarke AH. Transcranial Doppler ultrasound during galvanic labyrinth polarization depicts central vestibular processing, demonstrating bilateral vestibular projection. Eur J Neurosci. 2008; 28:372-8.
80. Dieterich M, Bense S, Stephan T, Brandt T, Schwaiger M, Bartenstein P. Medial vestibular nucleus lesions in Wallenberg's syndrome cause decreased activity of the contralateral vestibular cortex. Ann NY Acad Sci. 2005;1039: 368-83.
81. Fasold O, Von Brevern M, Kuhberg M, Ploner CJ, Villringer A, Lempert T, et al. Human vestibular cortex as identified with caloric stimulation in functional magnetic resonance imaging. Neuroimage. 2002;17:1384-93.
82. Wilson VJ, Zarzecki P, Schor RH, Isu N, Rose PK, Sato H, et al. Cortical influences on the vestibular nuclei of the cat . Exp Brain Res. 1999;125:1-13.
83. Licata F, Li VG, Maugeri G, Ciranna L, Santangelo F. Effects of glutamate on the serotonin-induced responses of vestibular neurons. Boll Soc Ital Biol Sper. 1990;66: 779-86.
84. Fukushima K, Takahashi K, Ohno M, Kato M. Responses of cat vestibular neurons to stimulation of the frontal cortex. Exp Brain Res. 1984;56:275-8.
85. Faugier-Grimaud S, Ventre J. Anatomic connections of inferior parietal cortex (area 7) with subcortical structures related to vestibulo-ocular function in a monkey (Macaca fascicularis). J Comp Neurol. 1989;280:1-14.
86. Fries W. Cortical projections to the superior colliculus in the macaque monkey: a retrograde study using horseradish peroxidase. J Comp Neurol. 1984;230:55-76.
87. Carmona JE, Holland AK, Harrison DW. Extending the functional cerebral systems theory of emotion to the vestibular modality: a systematic and integrative approach. Psychol Bull. 2009;135:286-302.
88. Bachtold D, Baumann T, Sandor PS, Kritos M, Regard M, Brugger P. Spatial- and verbal-memory improvement by cold-water caloric stimulation in healthy subjects. Exp Brain Res. 2001;136:128-32.
89. Schiff ND, Pulver M. Does vestibular stimulation activate thalamocortical mechanisms that reintegrate impaired cortical regions? Proc Biol Sci. 1999;266:421-3.
90. Gaffan D, Hornak J. Visual neglect in the monkey. Representation and disconnection. Brain. 1997;120:1647-57.
91. Swan L. Unilateral spatial neglect. Phys Ther. 2001;81: 1572-80.
92. Rinaldi C, Marangolo P, Pizzamiglio L. Between language and space: a cross-domain interaction. Neuroreport. 2003;14:1381-3.
93. Hills AE, Caramazza A. Spatially specific deficits in processing graphemic representations in reading and writing. Brain Lang. 1995;48:263-308.
94. Baxter DM, Warrington EK. Neglect dysgraphia. J Neurol Neurosurg Psychiatry. 1983;46:1073-8.
95. Geminiani G, Bottini G. Mental representation and temporary recovery from unilateral neglect after vestibular stimulation. J Neurol Neurosurg Psychiatry. 1992;55:332-3.
96. Rode G, Perenin MT. Temporary remission of representational hemineglect through vestibular stimulation. Neurore- port. 1994;5:869-72.
97. Guariglia C, Lippolis G, Pizzamiglio L. Somatosensory stimulation improves imagery disorders in neglect. Cortex. 1998;34:233-41.
98. Pizzamiglio L, Vallar G, Doricchi F. Gravitational inputs modulate visuospatial neglect. Exp Brain Res. 1997;117: 341-5.
99. Utz KS, Keller I, Kardinal M, Kerkhoff G. Galvanic ves- tibular stimulation reduces the pathological rightward line bisection error in neglect: a sham stimulation-controlled study. Neuropsychologia. 2011;49:1219-25.
100. Vallar G, Guariglia C, Magnotti L, Pizzamiglio L. Optokinetic stimulation affects both vertical and horizontal deficits of position sense in unilateral neglect. Cortex. 1995; 31:669-83.
101. Rode G, Tilikete C, Luaute J, Rossetti Y, Vighetto A, Boisson D. Bilateral vestibular stimulation does not improve visual hemineglect. Neuropsychologia. 2002;40: 1104-6.
102. Ramachandran VS, McGeoch PD, Williams L. Can vesti-bular caloric stimulation be used to treat Dejerine-Roussy syndrome? Med Hypotheses. 2007;69:486-8.
103. Dieterich M, Brandt T. Functional brain imaging of peripheral and central vestibular disorders. Brain. 2008; 131:2538-52.
104. Dieterich M, Brandt T. Imaging cortical activity after vestibular lesions. Restor Neurol Neurosci. 2010;28:47-56.
105. Philbeck JW, Behrmann M, Biega T, Levy L. Asymmetrical perception of body rotation after unilateral injury to human vestibular cortex. Neuropsychologia. 2006;44:1878-90.
106. Shinder ME, Taube JS. Differentiating ascending vestibular pathways to the cortex involved in spatial cognition. J Vestib Res. 2010;20:3-23.
107. Sans A, Raymond J, Marty R. Thalamic and cortical responses to electric stimulation of the vestibular nerve in the cat. Exp Brain Res. 1970;10:265-75.
108. Deecke L, Schwarz DW, Fredrickson JM. Vestibular responses in the rhesus monkey ventroposterior thalamus. II. Vestibulo-proprioceptive convergence at thalamic neurons. Exp Brain Res. 1977;30:219-32.
109. Meng H, May PJ, Dickman JD, Angelaki DE. Vestibular signals in primate thalamus: properties and origins. J Neurosci. 2007;27:13590-602.
110. Shiroyama T, Kayahara T, Yasui Y, Nomura J, Nakano K. Projections of the vestibular nuclei to the thalamus in the rat: a Phaseolus vulgaris leucoagglutinin study. J Comp Neurol. 1999;407:318-32.
111. Lopez C, Blanke O. The thalamocortical vestibular system in animals and humans. Brain Res Rev. 2011;67:119-46.
112. Deutschlander A, Bense S, Stephan T, Schwaiger M, Brandt T, Dieterich M. Sensory system interactions during simultaneous vestibular and visual stimulation in PET. Hum Brain Mapp. 2002;16:92-103.
113. Bucher SF, Dieterich M, Wiesmann M, Weiss A, Zink R, Yousry TA, et al. Cerebral functional magnetic resonance imaging of vestibular, auditory, and nociceptive areas during galvanic stimulation. Ann Neurol. 1998;44:120-5.
114. Hawrylyshyn PA, Rubin AM, Tasker RR, Organ LW, Fredrickson JM. Vestibulothalamic projections in man: a sixth primary sensory pathway. J Neurophysiol. 1978;41: 394-401.
115. Dieterich M, Bucher SF, Seelos KC, Brandt T. Horizontal or vertical optokinetic stimulation activates visual motion-sensitive, ocular motor and vestibular cortex areas with right hemispheric dominance. An fMRI study. Brain. 1998; 121:1479-95.
116. Ceballos-Baumann AO, Boecker H, Fogel W, Alesch F, Bartenstein P, Conrad B, et al. Thalamic stimulation for essential tremor activates motor and deactivates vestibular cortex. Neurology. 2001;56:1347-54.
117. Maguire EA, Hassabis D. Role of the hippocampus in imagination and future thinking. Proc Natl Acad Sci USA. 2011;108:E39.
118. Lee SA, Spelke ES. Two systems of spatial representation underlying navigation. Exp Brain Res. 2010;206:179-88.
119. Song EY, Kim YB, Kim YH, Jung MW. Role of active movement in place-specific firing of hippocampal neurons . Hippocampus. 2005;15:8-17.
120. Wiener SI, Berthoz A, Zugaro MB. Multisensory processing in the elaboration of place and head direction responses by limbic system neurons. Brain Res Cogn Brain Res. 2002; 14:75-90.
121. Yoganarasimha D, Knierim JJ. Coupling between place cells and head direction cells during relative translations and rotations of distal landmarks. Exp Brain Res. 2005;160: 344-59.
122. Hirshhorn M, Grady C, Rosenbaum RS, Winocur G, Moscovitch M. The hippocampus is involved in mental navigation for a recently learned, but not a highly familiar environment: a longitudinal fMRI study. Hippocampus. 2012;22:842-52.
123. Mullally SL, Maguire EA. A new role for the parahippoc-ampal cortex in representing space. J Neurosci. 2011; 31:7441-9.
124. Spiers HJ, Maguire EA. A navigational guidance system in the human brain . Hippocampus. 2007;17:618-26.
125. Spiers HJ, Maguire EA. Neural substrates of driving behaviour. Neuroimage. 2007;36:245-55.
126. Marsh R, Hao X, Xu D, Wang Z, Duan Y, Liu J, et al. A virtual reality-based FMRI study of reward-based spatial learning. Neuropsychologia. 2010;48:2912-21.
127. Rajimehr R, Devaney KJ, Bilenko NY, Young JC, Tootell RB. The 'parahippocampal place area' responds preferentially to high spatial frequencies in humans and monkeys. PLoS Biol. 2011;9:e1000608.
128. Wegman J, Janzen G. Neural encoding of objects relevant for navigation and resting state correlations with navigational ability. J Cogn Neurosci. 2011;23:3841-54.
129. Martinet LE, Sheynikhovich D, Benchenane K, Arleo A. Spatial learning and action planning in a prefrontal cortical network model. PLoS Comput Biol. 2011;7: e1002045.
130. Ciaramelli E, Rosenbaum RS, Solcz S, Levine B, Moscovitch M. Mental space travel: damage to posterior parietal cortex prevents egocentric navigation and re-experiencing of remote spatial memories. J Exp Psychol Learn Mem Cogn. 2010;36:619-34.
131. Maguire EA, Nannery R, Spiers HJ. Navigation around London by a taxi driver with bilateral hippocampal lesions. Brain. 2006;129:2894-907.
132. Woollett K, Maguire EA. Acquiring 'the Knowledge' of London's layout drives structural brain changes. Curr Biol. 2011;21:2109-14.
133. Maguire EA, Woollett K, Spiers HJ. London taxi drivers and bus drivers: a structural MRI and neuropsychological analysis. Hippocampus. 2006;16:1091-101.
134. Maguire EA, Gadian DG, Johnsrude IS, Good CD, Ashburner J, Frackowiak RS, et al. Navigation related structural change in the hippocampi of taxi drivers. Proc Natl Acad Sci USA. 2000;97:4398-403.
135. Maguire EA, Frackowiak RS, Frith CD. Recalling routes around London: activation of the right hippocampus in taxi drivers. J Neurosci. 1997;17:7103-10.
136. Astur RS, Taylor LB, Mamelak AN, Philpott L, Sutherland RJ. Humans with hippocampus damage display severe spatial memory impairments in a virtual Morris water task. Behav Brain Res. 2002;132:77-84.
137. Peruch P, Lopez C, Redon-Zouiteni C, Escoffier G, Zeitoun A, Sanjuan M, et al. Vestibular information is necessary for maintaining metric properties of representational space: evidence from mental imagery. Neuropsychologia. 2011;49:3136-4.
138. Tai SK, Ma J, Ossenkopp KP, Leung LS. Activation of immobility related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation. Hippocampus. 2012;22:914-25.
139. Muir GM, Taube J S. The neural correlates of navigation: do head direction and place cells guide spatial behaviour? Behav Cogn Neurosci Rev. 2002;1:297-317.
140. Yoder RM, Taube JS. Head direction cell activity in mice: robust directional signal depends on intact otolith organs. J Neurosci. 2009;29:1061-76.
141. Conner JM, Franks KM, Titterness AK, Russell K, Merrill DA, Christie BR, et al. NGF is essential for hippocampal plasticity and learning. J Neurosci. 2009; 29:10883-9.
142. McGaugh JL. The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu Rev Neurosci. 2004;27:1-28.
143. Floresco SB, Tse MT. Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala-prefrontal cortical pathway. J Neurosci. 2007;27:2045-57.
144. Britton JC, Taylor SF, Sudheimer KD, Liberzon I. Facial expressions and complex IAPS pictures: common and differential networks. Neuroimage. 2006;31:906-19.
145. Doyere V, Debiec J, Monfils MH, Schafe GE, Le Doux JE. Synapse-specific reconsolidation of distinct fear memories in the lateral amygdala . Nat Neurosci. 2007;10:414-6.
146. Nader K, Schafe GE, Le Doux JE. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature. 2000;406:722-6.
147. Whalen PJ, Kagan J, Cook RG, Davis FC, Kim H, Polis S, et al. Human amygdala responsivity to masked fearful eye whites. Science. 2004;306:2061.
148. Kilts CD, Egan G, Gideon DA, Ely TD, Hoffman JM. Dissociable neural pathways are involved in the recognition of emotion in static and dynamic facial expressions. Neuroimage. 2003;18:156-68.
149. Morris JS, Friston KJ, Buchel C, Frith CD, Young AW, Calder AJ, et al. A neuromodulatory role for the human amygdala in processing emotional facial expressions. Brain. 1998;121:47-57.
150. Kilts CD, Kelsey JE, Knight B, Ely TD, Bowman FD, Gross RE, et al. The neural correlates of social anxiety disorder and response to pharmacotherapy. Neuropsychop- harmacology. 2006;31:2243-53.
151. Vuilleumier P, Pourtois G. Distributed and interactive brain mechanisms during emotion face perception: evidence from functional neuroimaging. Neuropsychologia. 2007;45: 174-94.
152. Curthoys IS, Halmagyi GM. Vestibular compensation: a review of the oculomotor, neural, and clinical consequences of unilateral vestibular loss. J Vestib Res. 1995;5:67-107.
153. Borel L, Lopez C, Peruch P, Lacour M. Vestibular syndrome: a change in internal spatial representation. Neurophysiol Clin. 2008;38:375-89.
154. Lacour M, Xerri C, Hugon M. Compensation of postural reactions to fall in the vestibular neurectomized monkey. Role of the reamining labyrinthine afferences. Exp Brain Res. 1979;37:563-80.
155. Redfern MS, Talkowski ME, Jennings JR, Furman JM. Cognitive influences in postural control of patients with unilateral vestibular loss. Gait Posture. 2004;19:105-14.
156. Talkowski ME, Redfern MS, Jennings JR, Furman JM. Cognitive requirements for vestibular and ocular motor processing in healthy adults and patients with unilateral vestibular lesions . J Cogn Neurosci. 2005;17:1432-41.
157. Dutheil S, Lacour M, Tighilet B. Discovering a new functional neurogenic zone: the vestibular nuclei of the brainstem. Med Sci (Paris). 2011;27:605-13.
158. Lacour M, Tighilet B. Plastic events in the vestibular nuclei during vestibular compensation: the brain orchestration of a 'deafferentation' code. Restor Neurol Neurosci. 2010;28: 19-35.
159. Dutheil S, Brezun JM, Leonard J, Lacour M, Tighilet B. Neurogenesis and astrogenesis contribution to recovery of vestibular functions in the adult cat following unilateral vestibular neurectomy: cellular and behavioural evidence. Neuroscience. 2009;164:1444-56.
160. Tighilet B, Brezun JM, Sylvie GD, Gaubert C, Lacour M. New neurons in the vestibular nuclei complex after unilateral vestibular neurectomy in the adult cat. Eur J Neurosci. 2007;25:47-58.
161. Lopez C, Lacour M, Magnan J, Borel L. Visual field dependence- independence before and after unilateral vestibular loss. Neuroreport. 2006;17:797-803.
162. Borel L, Harlay F, Lopez C, Magnan J, Chays A, Lacour M. Walking performance of vestibular-defective patients before and after unilateral vestibular neurotomy. Behav Brain Res. 2004;150:191-200.
163. Lacour M, Barthelemy J, Borel L, Magnan J, Xerri C, Chays A, et al. Sensory strategies in human postural control before and after unilateral vestibular neurotomy. Exp Brain Res. 1997;115:300-10.
164. Mast FW, Merfeld DM, Kosslyn SM. Visual mental imagery during caloric vestibular stimulation. Neuropsychologia. 2006;44:101-9.
165. Wenzel R, Bartenstein P, Dieterich M, Danek A, Weindl A, Minoshima S, et al. Deactivation of human visual cortex during involuntary ocular oscillations. A PET activation study. Brain. 1996;119:101-10.
166. Tiecks FP, Planck J, Haberl RL, Brandt T. Reduction in posterior cerebral artery blood flow velocity during caloric vestibular stimulation. J Cereb Blood Flow Metab. 1996; 16:1379-82.
167. Dieterich M, Bauermann T, Best C, Stoeter P, Schlindwein P. Evidence for cortical visual substitution of chronic bilateral vestibular failure (an fMRI study). Brain. 2007; 130:2108-16.
168. Lopez C, Borel L, Magnan J, Lacour M. Torsional optoki-netic nystagmus after unilateral vestibular loss: asymmetry and compensation. Brain. 2005;128:1511-24.
169. Green JP, Barabasz AF, Barrett D, Montgomery GH. Forging ahead: the 2003 APA Division 30 definition of hypnosis. Int J Clin Exp Hypn. 2005;53:259-64.
170. Weitzenhoffer AM. Hypnotic susceptibility: a personal and historical note regarding the development and naming of the Stanford Scales . Int J Clin Exp Hypn. 1997;45:126-43.
171. Egner T, Jamieson G, Gruzelier J. Hypnosis decouples cognitive control from conflict monitoring processes of the frontal lobe. Neuroimage. 2005;27:969-78.
172. Jamieson GA, Sheehan PW. An empirical test of Woody and Bowers's dissociated control theory of hypnosis. Int J Clin Exp Hypn. 2004;52:232-49.
173. Spiegel D. Negative and positive visual hypnotic hallucinations: attending inside and out. Int J Clin Exp Hypn. 2003;51:130-6.
174. Tellegen A, Atkinson G. Openness to absorbing and self-altering experiences ('absorption'), a trait related to hypnotic susceptibility. J Abnorm Psychol. 1974;83: 268-77.
175. Castellani E, D'Alessandro L, Sebastiani L. Hypnotizability and spatial attentional functions. Arch Ital Biol. 2007;145: 23-37.
176. Fan J, Posner M. Human attentional networks . Psychiatr Prax. 2004;31:S210-4.
177. Jamieson GA, Sheehan PW. A critical evaluation of the relationship between sustained attentional abilities and hypnotic susceptibility. Contemporary Hypnosis. 2002;19:62-74.
178. Carli G, Cavallaro FI, Rendo CA, Santarcangelo EL. Imagery of different sensory modalities: hypnotizability and body sway. Exp Brain Res. 2007;179:147-54.
179. Lichtenberg P, Bachner-Melman R, Ebstein RP, Crawford HJ. Hypnotic susceptibility: multidimensional relationships with Cloninger's Tridimensional Personality Questionnaire, COMT polymorphisms, absorption, and attentional characteristics. Int J Clin Exp Hypn. 2004;52:47-72.
180. Nordby H, Hugdahl K, Jasiukaitis P, Spiegel D. Effects of hypnotizability on performance of a Stroop task and event-related potentials . Percept Mot Skills. 1999;88:819-30.
181. Rubichi S, Ricci F, Padovani R, Scaglietti L. Hypnotic susceptibility, baseline attentional functioning, and the Stroop task. Conscious Cogn. 2005;14:296-303.
182. Santarcangelo EL, Scattina E, Carli G, Macerata A, Manzoni D. Hypnotizability-dependent modulation of postural control: effects of alteration of the visual and leg proprioceptive inputs. Exp Brain Res. 2008;191:331-40.
183. Schwartz S, Segal O, Barkana Y, Schwesig R, Avni I, Morad Y. The effect of cataract surgery on postural control. Invest Ophthalmol Vis Sci. 2005;46:920-4.
184. Brannan S, Dewar C, Sen J, Clarke D, Marshall T, Murray PI. A prospective study of the rate of falls before and after cataract surgery. Br J Ophthalmol. 2003;87:560-2.
185. Ivers RQ, Cumming RG, Mitchell P, Attebo K. Visual impairment and falls in older adults: the Blue Mountains Eye Study. J Am Geriatr Soc. 1998;46:58-64.
186. Bronstein AM. Vision and vertigo: some visual aspects of vestibular disorders . J Neurol. 2004;251:381-7.
187. Bronstein AM. Visual vertigo syndrome: clinical and pos-turography findings. J Neurol Neurosurg Psychiatry. 1995; 59:472-6.
188. Guerraz M, Yardley L, Bertholon P, Pollak L, Rudge P, Gresty MA, et al. Visual vertigo: symptom assessment, spatial orientation and postural control. Brain. 2001;124: 1646-56.
189. Jacob RG, Furman JM, Durrant JD, Turner SM. Panic, agoraphobia, and vestibular dysfunction. Am J Psychiatry. 1996;153:503-12.
190. Shallo-Hoffmann J, Bronstein AM. Visual motion detection in patients with absent vestibular function. Vision Res. 2003;43:1589-94.
191. Ishikawa A, Nakamura S. Convergence and interaction of hippocampal and amygdalar projections within the prefron-tal cortex in the rat. J Neurosci. 2003;23:9987-95.
192. Borel L, Harlay F, Magnan J, Chays A, Lacour M. Deficits and recovery of head and trunk orientation and stabilization after unilateral vestibular loss. Brain. 2002;125:880-94.
193. Halmagyi GM, Weber KP, Curthoys IS. Vestibular function after acute vestibular neuritis. Restor Neurol Neurosci. 2010;28:37-46.
194. Lacour M, Dutheil S, Tighilet B, Lopez C, Borel L. Tell me your vestibular deficit, and I'll tell you how you'll compensate. Ann N Y Acad Sci. 2009;1164:268-78.
195. Peruch P, Borel L, Magnan J, Lacour M. Direction and distance deficits in path integration after unilateral vestibular loss depend on task complexity. Brain Res Cogn Brain Res. 2005;25:862-72.
196. Biaggioni I, Costa F, Kaufmann H. Vestibular influences on autonomic cardiovascular control in humans. J Vestib Res. 1998;8:35-1.
197. Ray CA, Carter JR. Vestibular activation of sympathetic nerve activity. Acta Physiol Scand. 2003;177:313-9.
198. Ray CA, Monahan KD. The vestibulosympathetic reflex in humans: neural interactions between cardiovascular reflexes. Clin Exp Pharmacol Physiol. 2002;29:98-102.
199. Yates BJ. Vestibular influences on the sympathetic nervous system. Brain Res Brain Res Rev. 1992;17:51-9.
200. Yates BJ, Aoki M, Burchill P, Bronstein AM, Gresty MA. Cardiovascular responses elicited by linear acceleration in humans. Exp Brain Res. 1999;125:476-84.
201. Yates BJ, Billig I, Cotter LA, Mori RL, Card JP. Role of the vestibular system in regulating respiratory muscle activity during movement. Clin Exp Pharmacol Physiol. 2002;29:112-7.
202. Yates BJ, Holmes MJ, Jian BJ. Adaptive plasticity in vestibu-lar influences on cardiovascular control. Brain Res Bull. 2000;53:3-9.
203. Yates BJ, Kerman IA. Post-spaceflight orthostatic intolerance: possible relationship to microgravity-induced plasticity in the vestibular system. Brain Res Brain Res Rev. 1998; 28:73-82.
204. Fuller PM, Jones TA, Jones SM, Fuller CA. Evidence for macular gravity receptor modulation of hypothalamic, limbic and autonomic nuclei. Neuroscience. 2004;129:461-71.
205. Ray CA. Interaction of the vestibular system and baroreflexes on sympathetic nerve activity in humans . Am J Physiol Heart Circ Physiol. 2000;279:H2399-04.
206. Abe C, Kawada T, Sugimachi M, Morita H. Interaction between vestibulo-cardiovascular reflex and arterial barore-flex during postural change in rats . J Appl Physiol. 2011; 111:1614-21.
207. Jauregui-Renaud K, Hermosillo AG, Gomez A, Marquez MF, Cardenas M, Bronstein AM. Vestibular function interferes in cardiovascular reflexes (corrected). Arch Med Res. 2003;34:200-4.
208. Doba N, Reis DJ. Role of the cerebellum and the vestibular apparatus in regulation of orthostatic reflexes in the cat. Circ Res. 1974;40:9-18.
209. Yates BJ, Bronstein AM. The effects of vestibular system lesions on autonomic regulation: observations, mechanisms, and clinical implications. J Vestib Res. 2005;15:119-29.
210. Grimm RJ, Hemenway WG, Lebray PR, Black FO. The perilymph fistula syndrome defined in mild head trauma . Acta Otolaryngol Suppl. 1989;464:1-40.
211. Berthoz A. Neural basis of spatial orientation and memory of routes: topokinetic memory or topokinesthesic memory. Rev Neurol (Paris). 2001;157:779-89.
212. Woollett K, Maguire EA. The effect of navigational expertise on wayfinding in new environments. J Environ Psychol. 2010;30:565-73.
213. Spiers HJ, Maguire EA. Decoding human brain activity during real-world experiences. Trends Cogn Sci. 2007; 11:356-65.
214. Maguire EA, Spiers HJ, Good CD, Hartley T, Frackowiak RS, Burgess N. Navigation expertise and the human hippocampus: a structural brain imaging analysis. Hippocampus. 2003;13:250-9.
215. Kumaran D, Hassabis D, Spiers HJ, Vann SD, Vargha-Khadem F, Maguire EA. Impaired spatial and non-spatial configural learning in patients with hippocampal pathology. Neuropsychologia. 2007;45:2699-711.
216. Dombeck DA, Harvey CD, Tian L, Looger LL, Tank DW. Functional imaging of hippocampal place cells at cellular resolution during virtual navigation. Nat Neurosci. 2010; 13:1433-40.
217. Hardt O, Nadel L. Cognitive maps and attention. Prog Brain Res. 2009;176:181-94.
218. Jacobs LF. The evolution of the cognitive map. Brain Behav Evol. 2003;62:128-39.
219. Vargas JP, Petruso EJ, Bingman VP. Hippocampal formation is required for geometric navigation in pigeons. Eur J Neurosci. 2004;20:1937-4.
220. Poucet B, Cressant A, Lenck-Santini PP, Save E. Neural basis for spatial memory in animals: what do hippocampal neurons tell us?. J Soc Biol. 2001;195:355-61.
221. Poucet B, Alvernhe A, Hok V, Renaudineau S, Sargolini F, Save E. The hippocampus and the neural code of spatial memory. Biol Aujourdhui. 2010;204:103-12.
222. Poucet B, Lenck-Santini PP, Paz-Villagran V, Save E. Place cells, neocortex and spatial navigation: a short review. J Physiol Paris. 2003;97:537-46.
223. Jeffery KJ, Anderson MI, Hayman R, Chakraborty S. A proposed architecture for the neural representation of spatial context. Neurosci Biobehav Rev. 2004;28:201-18.
224. Jeffery KJ. Integration of the sensory inputs to place cells: what, where, why, and how? Hippocampus. 2007;17: 775-85.
225. Johnson A, Seeland K, Redish AD. Reconstruction of the post-subiculum head direction signal from neural ensembles. Hippocampus. 2005;15:86-96.
226. Kubie JL, Fenton AA. Heading-vector navigation based on head-direction cells and path integration. Hippocampus. 2009;19:456-79.
227. Giocomo LM, Moser MB, Moser EI. Computational models of grid cells. Neuron. 2011;71:589-603.
228. Hafting T, Fyhn M, Molden S, Moser MB, Moser EI. Microstructure of a spatial map in the entorhinal cortex. Nature. 2005;436:801-6.
229. Jeffery KJ. Place cells, grid cells, attractors, and remapping. Neural Plast. 2011;2011:182602. doi:10.1155/2011/182602. Epub 2011 Nov 3. PMID: 22135756.
230. Wills TJ, Cacucci F, Burgess N, O'Keefe J. Development of the hippocampal cognitive map in preweanling rats. Science. 2010;328:1573-6.
231. Langston RF, Ainge JA, Couey JJ, Canto CB, Bjerknes TL, Witter MP, et al. Development of the spatial representation system in the rat. Science. 2010;328:1576-80.
232. O'Mara SM, Rolls ET, Berthoz A, Kesner RP. Neurons responding to whole-body motion in the primate hippocampus. J Neurosci. 1994;14:6511-23.
233. Stackman RW, Walsh TJ, Brucato FH, Swartzwelder HS. Medial septal benzodiazepine receptors modulate hippoc-ampal evoked responses and long-term potentiation. Brain Res. 1996;717:12-21.
234. Taube JS, Goodridge JP, Golob EJ, Dudchenko PA, Stackman RW. Processing the head direction cell signal: a review and commentary. Brain Res Bull. 1996;40: 477-84.
235. Wiener SI, Korshunov VA, Garcia R, Berthoz A. Inertial, substratal and landmark cue control of hippocampal CA1 place cell activity. Eur J Neurosci. 1995;7:2206-19.
236. Taube JS. Head direction cell firing properties and behavioural performance in 3-D space. J Physiol. 2011; 589:835-41.
237. Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Lesions of the vestibular system disrupt hippocampal theta rhythm in the rat. J Neurophysiol. 2006;96:4-14.
238. Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Bilateral peripheral vestibular lesions produce long-term changes in spatial learning in the rat. J Vestib Res. 2003; 13:9-16.
239. Beraneck M, Lambert FM. Impaired perception of gravity leads to altered head direction signals: what can we learn from vestibular-deficient mice? J Neurophysiol. 2009; 102:12-4.
240. Brown JE, Yates BJ, Taube !S. Does the vestibular system contribute to head direction cell activity in the rat? Physiol Behav. 2002;77:743-8.
241. Telford L, Howard IP, Ohmi M. Heading judgments during active and passive self-motion. Exp Brain Res. 1995;104: 502-10.
242. Zhang RL, Zhang ZG, Zhang L, Chopp M. Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischaemia. Neuroscience. 2001;105:33-41.
243. Liu P, Zheng Y, King J, Darlington CL, Smith PF. Long-term changes in hippocampal n-methyl-D-aspartate receptor subunits following unilateral vestibular damage in rat. Neuroscience. 2003;117:965-70.
244. Zheng Y, Smith PF, Darlington CL. Subregional analysis of amino acid levels in the guinea pig hippocampus following unilateral vestibular deafferentation. J Vestib Res. 1999;9: 335-45.
245. Zheng Y, Smith PF, Darlington CL. Noradrenaline and serotonin levels in the guinea pig hippocampus following unilateral vestibular deafferentation. Brain Res. 1999; 836:199-202.
246. Smith PF, Brandt T, Strupp M, Darlington CL, Zheng Y. Balance before reason in rats and humans. Ann N Y Acad Sci. 2009;1164:127-33.
247. Goddard M, Zheng Y, Darlington CL, Smith PF. Monoamine transporter and enzyme expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss . Neurosci Lett. 2008;437:107-10.
248. Goddard M, Zheng Y, Darlington CL, Smith PF. Synaptic protein expression in the medial temporal lobe and frontal cortex following chronic bilateral vestibular loss. Hippocampus. 2008;18:440-4.
249. Russell NA, Horii A, Smith PF, Darlington CL, Bilkey DK. Long-term effects of permanent vestibular lesions on hip-pocampal spatial firing. J Neurosci. 2003;23:6490-8.
250. Zheng Y, Darlington CL, Smith PF. Impairment and recovery on a food foraging task following unilateral vestibular deafferentation in rats. Hippocampus. 2006;16:368-78.
251. Zheng Y, Mason-Parker SE, Logan B, Darlington CL, Smith PF, Abraham WC. Hippocampal synaptic transmission and LTP in vivo are intact following bilateral vestibular deafferentation in the rat. Hippocampus. 2010;20:461-8.
252. Stackman RW, Clark AS, Taube JS. Hippocampal spatial representations require vestibular input. Hippocampus. 2002;12:291-303.
253. Brandt T, Schautzer F, Hamilton DA, Bruning R, Markow-itsch HJ, Kalla R, et al. Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans. Brain. 2005;128:2732-1.
254. Schautzer F, Hamilton D, Kalla R, Strupp M, Brandt T. Spatial memory deficits in patients with chronic bilateral vestibular failure. Ann N Y Acad Sci. 2003;1004:316-24.
255. Peruch P, Borel L, Gaunet F, Thinus-Blanc G, Magnan J, Lacour M. Spatial performance of unilateral vestibular defective patients in non-visual versus visual navigation. J Vestib Res. 1999;9:37-47.
256. Guidetti G, Monzani D, Trebbi M, Rovatti V. Impaired navigation skills in patients with psychological distress and chronic peripheral vestibular hypofunction without vertigo. Acta Otorhinolaryngol Ital. 2008;28:21-5.
257. Smith PF, ZhengY, Horii A, Darlington CL. Does vestibular damage cause cognitive dysfunction in humans? J Vestib Res. 2005;15:1-9.
258. Hufner K, Hamilton DA, Kalla R, Stephan T, Glasauer S, Ma J., et al. Spatial memory and hippocampal volume in humans with unilateral vestibular deafferentation. Hippocampus. 2007;17:471-85.
259. Baumann O, Skilleter AJ, Mattingley JB. Short-term memory maintenance of object locations during active navigation: which working memory subsystem is essential? PLoS One. 2011;6:e19707.
260. Aversano M, Sacchi R, Memoli R, Graziano A, Petrosini L. Anterograde and retrograde influence of vestibular stimulation on spatial working memory. Physiol Behav. 2002;76:655-60.
261. Guidetti G, Monzani D, Trebbi M, Rovatti V. Peripheral vestibular damage causes impaired navigation tasks on memorized routes in humans. Ann Otolaryngol Chir Cervicofac. 2007;124:197-201.
262. Pini LA, Guidetti G, Brovia D, Pontremoli P, Sarchielli P. Topo-kinesthetic memory in chronic headaches. A new test for chronic patients: preliminary report. J Headache Pain. 2005;6:448-54.
263. Brookes GB, Gresty MA, Nakamura T, Metcalfe T. Sensing and controlling rotational orientation in normal subjects and patients with loss of labyrinthine function. Am J Otol. 1993;14:349-51.
264. Monzani D, Casolari L, Guidetti G, Rigatelli M. Psychological distress and disability in patients with vertigo. J Psychosom Res. 2001;50:319-23.
265. Yardley L, Masson E, Verschuur C, Haacke N, Luxon L. Symptoms, anxiety and handicap in dizzy patients: development of the vertigo symptom scale. J Psychosom Res. 1992;36:731-41.
266. Yardley L, Redfern MS. Psychological factors influencing recovery from balance disorders. J Anxiety Disord. 2001; 15:107-19.
267. Jauregui-Renaud K, Sang FY, Gresty MA, Green DA, Bronstein AM. Depersonalization/derealization symptoms and updating orientation in patients with vestibular disease. J Neurol Neurosurg Psychiatry. 2008;79:276-83.
268. Toupet M, Chassany O, Rothoft JM, Bremaud des Ouilleres L. Vertiginous complaints: usual presentation in private practice and concrete aspects of care and management. Otorhinolaryngol Nova. 2002;12:276-81.
269. Brown R, Kulik J Flashbulb memories. Cognition. 1977; 5:73-99.
270. Geuze E, Vermetten E, Ruf M, de Kloet CS, Westenberg HG. Neural correlates of associative learning and memory in veterans with post-traumatic stress disorder. J Psychiatr Res. 2008;42:659-69.
271. Maren S. Synaptic mechanisms of associative memory in the amygdala. Neuron. 2005;47:783-6.
272. Teggi R, Caldirola D, Colombo B, Perna G, Comi G, Bellodi L, et al. Dizziness, migrainous vertigo and psychiatric disorders . J Laryngol Otol. 2010;124:285-90.
273. Jacob RG, Furman JM, Perel JM. Panic, Phobia and Vestibular Dysfunction. In: Yates BJ, Miller AS (editors). Vestibular Autonomic Regulation. CRC Press Inc; 1996.
274. Yardley L, Britton J, Lear S, Bird J, Luxon LM. Relationship between balance system function and agoraphobic avoidance. Behav Res Ther. 1995;33:435-9.
275. Yardley L, Luxon L, Lear S, Britton J, Bird J. Vestibular and posturographic test results in people with symptoms of panic and agoraphobia . J Audiol Med. 1994;3:48-65.
276. Ulmer E, Bernard-Demanze L, Lacour M. Statistical study of normal canal deficit variation range. Measurement using the Head Impulse Test video system. Eur Ann Otorhi-nolaryngol Head Neck Dis. 2011;128:278-82.
277. Bridgeman B, Hendry D, Stark L. Failure to detect displacement of the visual world during saccadic eye movements. Vision Res. 1975;15:719-22.
278. Henderson JM, Hollingworth A. Global trans-saccadic change blindness during scene perception. Psychol Sci. 2003;14:493-7.
279. Ibbotson MR, Crowder NA, Cloherty SL, Price NS, Mustari MJ. Saccadic modulation of neural responses: possible roles in saccadic suppression, enhancement, and time compression. J Neurosci. 2008;28:10952-60.
280. Von der Heydt R, Friedman HS. Searching for the neural mechanisms of colour filling-in. In: de Weerd P (editor). Filling from perceptual completion to cortical reorganization. Oxford University Press; 2003. pp. 106-27.
281. Elliott MA. Predicting motorcyclists' intentions to speed: effects of selected cognitions from the theory of planned behaviour, self-identity and social identity. Accid Anal Prev. 2010;42:718-25.
282. McConkie GW. Perceiving a stable visual world. In: van Rensbergen JM, Devijver M, D'Ydewalle G (editors). Proceedings of the sixth european conference on eye movements. Belgium: University of Leuven, Belgium: Laboratory of Experimental Psychology; 1991. pp. 5-7.
283. Grimes J. On the failure to detect changes in scenes across saccades. In: Atkins K (editor). Perception: Vancouver studies in cognitive science. New York: Oxford University Press; 1996. pp. 89-110.
284. McConkie GW, Currie CB. Visual stability across saccades while viewing complex pictures. J Exp Psychol Hum Percept Perform. 1996;22:563-81.
285. Luck SJ, Vogel EK. The capacity of visual working memory for features and conjunctions. Nature. 1997;390: 279-81.
286. Rensink RA, O'Regan JK, Clark JJ. To see or not to see: the need for attention to perceive changes in scenes. Psychol Sci. 1997;8:368-73.
287. Rensink RA. The dynamic representation of scenes. Visual Cognition. 2000;7:17-42 288.
288. Rensink RA. Visual search for change: a probe into the nature of attentional processing. Visual Cognition. 2000; 7:345-76.
289. Simons DJ, Rensink RA. Change blindness: past, present, and future. Trends Cogn Sci. 2005;9:16-20.
290. Rensink RA. Change detection. Annu Rev Psychol. 2002; 53:245-77.
291. O'Regan JK, Rensink RA, Clarke JJ. 'Mudsplashes' render picture changes invisible. Invest Ophthalmol Vis Sci. 1996; 37:213.
292. White CB, Caird JK. The blind date: the effects of change blindness, passenger conversation and gender on looked- but-failed-to-see (LBFTS) errors. Accid Anal Prev. 2010; 42:1822-30.
293. Shubert TE, McCulloch K, Hartman M, Giuliani CA. The effect of an exercise-based balance intervention on physical and cognitive performance for older adults: a pilot study. J Geriatr Phys Ther. 2010;33:157-64.
294. Zheng Y, Darlington CL, Smith PF. Bilateral labyrinthec-tomy causes long-term deficit in object recognition in rat . Neuroreport. 2004;15:1913-6.
295. Risey J, Briner W. Dyscalculia in patients with vertigo. J Vestib Res. 1990;1:31-7.
296. Andersson G, Hagman J, Talianzadeh R, Svedberg A, Larsen HC. Dual-task study of cognitive and postural interference in patients with vestibular disorders. Otol Neurotol. 2003;24:289-93.
297. Gresty MA, Golding JF. Impact of vertigo and spatial diso-rientation on concurrent cognitive tasks. Ann N Y Acad Sci. 2009;1164:263-7.
298. Nascimbeni A, Gaffuri A, Penno A, Tavoni M. Dual task interference during gait in patients with unilateral vestibular disorders. J Neuroeng Rehabil. 2010;7:47.
299. Orgogozo JM. New millennium: new expectations for Alzheimer's disease? Dement Geriatr Cogn Disord. 2000;11:1-2.
300. Orgogozo JM, Abadie E. Vascular dementia: European perspectives. Alzheimer Dis Assoc Disord. 1999;13:S192-200.
301. Fabrigoule C, Rouch I, Taberly A, Letenneur L, Commenges D, Mazaux JM, et al. Cognitive process in preclinical phase of dementia. Brain. 1998;121:135-41.
302. Spiro A III, Brady CB. Integrating health into cognitive aging: toward a preventive cognitive neuroscience of aging. J Gerontol B Psychol Sci Soc Sci. 2011;66:17-25.
303. Nowrangi MA, Rao V, Lyketsos CG. Epidemiology, assessment, and treatment of dementia. Psychiatr Clin North Am. 2011;34:275-94.
304. Nelson PT, Head E, Schmitt FA, Davis PR, Neltner JH, Jicha GA, et al. Alzheimer's disease is not 'brain aging': neuropathological, genetic, and epidemiological human studies. Acta Neuropathol. 2011;121:571-87.
305. Negash S, Smith GE, Pankratz S, Aakre J, Geda YE, Roberts RO, et al. Successful aging: definitions and prediction of longevity and conversion to mild cognitive impairment. Am J Geriatr Psychiatry. 2011;19:581-8.
306. Dartigues JF, Fabrigoule C, Barberger-Gateau P, Orgogozo JM. Memory, aging and risk factors: lessons from clinical trials and epidemiologic studies. Therapie. 2000; 55:503-5.
307. Sanders JB, Bremmer MA, Comijs HC, Deeg DJ, Lampe IK, Beekman AT. Cognitive functioning and the natural course of depressive symptoms in late life. Am J Geriatr Psychiatry. 2011;19:664-72.
308. Singh-Manoux A, Marmot MG, Glymour M, Sabia S, Kivimaki M, Dugravot A. Does cognitive reserve shape cognitive decline? Ann Neurol. 2011;70:296-304.
309. Wilson RS, Begeny CT, Boyle PA, Schneider JA, Bennett DA. Vulnerability to stress, anxiety, and development of dementia in old age. Am J Geriatr Psychiatry. 2011;19:327-34.
310. Plassman BL, Langa KM, McCammon RJ, Fisher GG, Potter GG, Burke JR, et al. Incidence of dementia and cognitive impairment, not dementia in the United States . Ann Neurol. 2011;70:418-26.
311. Borson S. Cognition, aging, and disabilities: conceptual issues. Phys Med Rehabil Clin N Am. 2010;21:375-82.
312. Proust-Lima C, Amieva H, Letenneur L, Orgogozo JM, Jacqmin-Gadda H, Dartigues JF. Gender and education impact on brain aging: a general cognitive factor approach. Psychol Aging. 2008;23:608-20.
313. Peres K, Helmer C, Amieva H, Matharan F, Carcaillon L, Jacqmin-Gadda H, et al. Gender differences in the prodromal signs of dementia: memory complaint and IADL restriction. a prospective population based cohort. J Alzheimers Dis. 2011;27:39-47.
314. Carpenter MG, Adkin AL, Brawley LR, Frank JS. Postural, physiological and psychological reactions to challenging balance: does age make a difference? Age Ageing. 2006;35:298-303.
315. Gufoni M, Guidetti G, Nuti D, Pagnini P, Vicini C, Tinelli C, et al. The relationship between cognitive impairment, anxiety-depression symptoms and balance and spatial orientation complaints in the elderly. Acta Otorhinolaryngol Ital. 2005;25:12-21.
316. Head D, Rodrigue KM, Kennedy KM, Raz N. Neuroanatomical and cognitive mediators of age-related differences in episodic memory. Neuropsychology. 2008;22: 491-507.
317. Jenkins L, Myerson J, Joerding JA, Hale S. Converging evidence that visuospatial cognition is more age-sensitive than verbal cognition. Psychol Aging. 2000;15:157-75.
318. Brown LA, Sleik RJ, Polych MA, Gage WH. Is the prioritization of postural control altered in conditions of postural threat in younger and older adults? J Gerontol A Biol Sci Med Sci. 2002;57:M785-92.
319. Rapp MA, Krampe RT, Baltes PB. Adaptive task prioritization in aging: selective resource allocation to postural control is preserved in Alzheimer's disease. Am J Geriatr Psychiatry. 2006;14:52-61.
320. Lacour M, Bernard-Demanze L, Dumitrescu M. Posture control, aging, and attention resources: models and posture-analysis methods. Neurophysiol Clin. 2008;38:411-21.
321. van Guilder HD, Farley JA, Yan H, van Kirk CA, Mitschelen M, Sonntag WE, et al. Hippocampal dysregula- tion of synaptic plasticity-associated proteins with age-related cognitive decline. Neurobiol Dis. 2011;43:201-12.
322. van Praag H, Shubert T, Zhao C, Gage FH. Exercise enhances learning and hippocampal neurogenesis in aged mice. J Neurosci. 2005;25:8680-5.
323. Lister JP, Barnes CA. Neurobiological changes in the hippocampus during normative aging. Arch Neurol. 2009;66: 829-33.
324. Singer T, Lindenberger U, Baltes PB. Plasticity of memory for new learning in very old age: a story of major loss? Psychol Aging. 2003;18:306-17.
325. Antonova E, Parslow D, Brammer M, Dawson GR, Jackson SH, Morris RG. Age-related neural activity during allocentric spatial memory. Memory. 2009;17:125-43.
326. Meulenbroek O, Petersson KM, Voermans N, Weber B, Fernandez G. Age differences in neural correlates of route encoding and route recognition. Neuroimage. 2004;22: 1503-14.
327. Moffat SD, Elkins W, Resnick SM. Age differences in the neural systems supporting human allocentric spatial navigation. Neurobiol Aging. 2006;27:965-72.
328. Moffat SD, Kennedy KM, Rodrigue KM, Raz N. Extrahippocampal contributions to age differences in human spatial navigation. Cereb Cortex. 2007;17:1274-82.
329. Rodgers MK, Sindone JA III, Moffat SD. Effects of age on navigation strategy. Neurobiol Aging. 2012;33:202-22.
330. Hubert V, Beaunieux H, Chetelat G, Platel H, Landeau B, Viader F, et al. Age-related changes in the cerebral substrates of cognitive procedural learning. Hum Brain Mapp. 2009;30:1374-86.
331. Ribeiro AS, Pereira JS. Balance improvement and reduction of likelihood of falls in older women after Cawthorne and Cooksey exercises. Braz J Otorhinolaryngol. 2005;71: 38-46.
332. Lovden M, Schaefer S, Noack H, Bodammer NC, Kuhn S, Heinze HJ, et al. Spatial navigation training protects the hippocampus against age-related changes during early and late adulthood. Neurobiol Aging. 2012;33:620.
333. Hines M. Brain gender. Oxford University Press; 2005.
334. Hines M. Sex-related variation in human behaviour and the brain. Trends Cogn Sci. 2010;14:448-56.
335. Halpern D. Sex differences in cognitive abilities. Lawrence Erlbaum Associates; 2000.
336. Ishii C, Nishino LK, Campos CA. Vestibular characterization in the menstrual cycle. Braz J Otorhinolaryngol. 2009;75:375-80.
337. Norman JF, Crabtree CE, Clayton AM, Norman HF. The perception of distances and spatial relationships in natural outdoor environments . Perception. 2005;34:1315-24.
338. Fields AW, Shelton AL. Individual skill differences and large-scale environmental learning. J Exp Psychol Learn Mem Cogn. 2006;32:506-15.
339. Wolbers T, Hegarty M. What determines our navigational abilities? Trends Cogn Sci. 2010;14:138-46.
340. Ruiz-Opazo N, Tonkiss J. Genome-wide scan for quantitative trait loci influencing spatial navigation and social recognition memory in Dahl rats. Physiol Genomics. 2006; 26:145-51.
341. Mizuno M, Yamada K, Olariu A, Nawa H, Nabeshima T. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats . J Neurosci. 2000;20:7116-21.
342. Hariri AR, Goldberg TE, Mattay VS, Kolachana BS, Callicott JH, Egan MF, et al. Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance. J Neurosci 2003;23:6690-4.
343. Bueller JA, Aftab M, Sen S, Gomez-Hassan D, Burmeister M, Zubieta JK. BDNF val66met allele is associated with reduced hippocampal volume in healthy subjects. Biol Psychiatry. 2006;59:812-5.
344. Bohbot VD, Lerch J, Thorndycraft B, Iaria G, Zijdenbos AP. Grey matter differences correlate with spontaneous strategies in a human virtual navigation task. J Neurosci. 2007; 27:10078-83.
345. Sneider JT, Sava S, Rogowska J, Yurgelun-Todd DA. A preliminary study of sex differences in brain activation during a spatial navigation task in healthy adults. Percept Mot Skills. 2011;113:461-80.
346. Lovden M, Herlitz A, Schellenbach M, Grossman-Hutter B, Kruger A, Lindenberger U. Quantitative and qualitative sex differences in spatial navigation. Scand J Psychol. 2007;48:353-8.
347. Gron G, Wunderlich AP, Spitzer M, Tomczak R, Riepe MW. Brain activation during human navigation: gender-different neural networks as substrate of performance. Nat Neurosci. 2000;3:404-8.
348. Sandstrom NJ, Kaufman J, Huettel SA. Males and females use different distal cues in a virtual environment navigation task. Brain Res Cogn Brain Res. 1998;6:351-60.
349. Moffat SD, Hampson E, Hatzipantelis M. Navigation in a 'virtual' maze: sex differences and correlation with psychometric measures of spatial ability in humans. Evol Hum Behav. 1998;19:73-87.
350. Montello DR, Lovelace KL, Golledge RG, Self CM. Sex-related differences and similarities in geographic and environmental spatial abilities. Ann Assoc Am Geogr. 1999;89:515-34.
351. Waller D. Individual differences in spatial learning from computer-simulated environments. J Exp Psychol Appl. 2000;6:307-21.
352. Jonasson Z. Meta-analysis of sex differences in rodent models of learning and memory: a review of behavioural and biological data. Neurosci Biobehav Rev. 2005;28:811-25.
353. Coluccia E, Louse G. Gender differences in spatial orientation: a review. J Environ Psychol. 2004;24:329-40.
354. Chabanne V. Sex differences and women's hormonal cycle effect on spatial performance in a virtual environment navigation task. Curr Psychol Cogn. 2004;22:351-75.
355. Voyer D, Postma A, Brake B, Imperato-McGinley J. Gender differences in object location memory: a meta-analysis. Psychon Bull Rev. 2007;14:23-38.
356. Burgess N, Spiers HJ, Paleologou E. Orientational manoeuvres in the dark: dissociating allocentric and egocentric influences on spatial memory. Cognition. 2004;94:149-66.
357. Chai XJ, Jacobs LF. Sex differences in directional cue use in a virtual landscape. Behav Neurosci. 2009;123:276-83.
358. Lawton CA. Gender differences in wayfinding strategies: relationship to spatial ability and spatial anxiety. Sex Roles. 1994;30:765-79.
359. Saucier DM, Green SM, Leason J, MacFadden A, Bell S, Elias LJ. Are sex differences in navigation caused by sexually dimorphic strategies or by differences in the ability to use the strategies? Behav Neurosci. 2002;116:403-10.
360. Woolley DG, Vermaercke B, Op de BH, Wagemans J, Gantois I, D'Hooge R, et al. Gender differences in human virtual water maze performance: novel measures reveal the relative contribution of directional responding and spatial knowledge. Behav Brain Res. 2010;208:408-14.
361. Lawton CA, Kallai J. Gender differences in wayfinding strategies and anxiety about wayfinding: a cross-cultural comparison. Sex Roles. 2002;47:389-401.
362. Gill-Body KM, Beninato M, Krebs DE. Relationship among balance impairments, functional performance, and disability in people with peripheral vestibular hypofunction. Phys Ther. 2000;80:748-58.
363. Kirby SE, Yardley L. Cognitions associated with anxiety in Meniere's disease . J Psychosom Res. 2009;66:111-8.
364. Yardley L, Gardner M, Bronstein A, Davies R, Buckwell D, Luxon L. Interference between postural control and mental task performance in patients with vestibular disorder and healthy controls. J Neurol Neurosurg Psychiatry. 2001; 71:48-52.
365. Yardley L, Owen N, Nazareth I, Luxon L. Panic disorder with agoraphobia associated with dizziness: characteristic symptoms and psychosocial sequelae. J Nerv Ment Dis. 2001;189:321-7.
366. Staab P, Ruckenstein MJ. Chronic dizziness and anxiety: effect of course of illness on treatment outcome. Arch Otolaryngol Head Neck Surg. 2005;131:675-9.
367. Eckhardt-Henn A, Best C, Bense S, Breuer P, Diener G, Tschan R, et al. Psychiatric comorbidity in different organic vertigo syndromes. J Neurol. 2008;255:420-8.
368. Wiltink J, Tschan R, Michal M, Subic-Wrana C, Eckhardt-Henn A, Dieterich M, et al. Dizziness: anxiety, health care utilization and health behaviour: results from a representative German community survey. J Psychosom Res. 2009;66:417-24.
369. Heinrichs N, Edler C, Eskens S, Mielczarek MM, Moschner C. Predicting continued dizziness after an acute peripheral vestibular disorder. Psychosom Med. 2007; 69:700-7.
370. Godemann F, Schabowska A, Naetebusch B, Heinz A, Strohle A. The impact of cognitions on the development of panic and somatoform disorders: a prospective study in patients with vestibular neuritis. Psychol Med. 2006;36: 99-108.
371. Furay AR, Bruestle AE, Herman JP. The role of the forebrain glucocorticoid receptor in acute and chronic stress. Endocrinology. 2008;149:5482-90.
372. Horner KC. The emotional ear in stress. Neurosci Biobehav Rev. 2003;27:437-46.
373. Seemungal BM, Gresty MA, Bronstein AM. The endocrine system, vertigo and balance. Curr Opin Neurol. 2001;14: 27-34.
374. Tighilet B, Manrique C, Lacour M. Stress axis plasticity during vestibular compensation in the adult cat. Neuro-science. 2009;160:716-30.
375. Darlington CL, Dutia MB, Smith PF. The contribution of the intrinsic excitability of vestibular nucleus neurons to recovery from vestibular damage. Eur J Neurosci. 2002;15:1719-27.
376. Straka H, Vibert N, Vidal PP, Moore LE, Dutia MB. Intrinsic membrane properties of vertebrate vestibular neurons: function, development and plasticity. Prog Neuro-biol. 2005;76:349-92.
377. Gliddon CM, Smith PF, Darlington CL. Interaction between the hypothalamic-pituitary-adrenal axis and behavioural compensation following unilateral vestibular deafferenta- tion. Acta Otolaryngol. 2003;123:1013-21.
378. Ariyasu L, Byl FM, Sprague MS, Adour KK. The beneficial effect of methylprednisolone in acute vestibular vertigo. Arch Otolaryngol Head Neck Surg. 1990;116:700-3.
379. Strupp M, Zingler VC, Arbusow V, Niklas D, Maag KP, Dieterich M, et al. Methylprednisolone, valacyclovir, or the combination for vestibular neuritis. N Engl J Med. 2004; 351:354-61.
380. Fishman JM, Burgess C, Waddell A. Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis). Cochrane Database Syst Rev 2011; 5:CD008607.
381. Compagnone NA, Mellon SH. Neurosteroids: biosynthesis and function of these novel neuromodulators. Front Neu-roendocrinol. 2000;21:1-56.
382. Reddy DS, Rogawski MA. Stress-induced deoxycorticoster-one-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility. J Neurosci. 2002;22:3795-805.
383. Lambert JJ, Belelli D, Peden DR, Vardy AW, Peters JA. Neurosteroid modulation of GABAA receptors. Prog Neurobiol. 2003;71:67-80.
384. McEwen BS, Seeman T. Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Ann N Y Acad Sci. 1999;896:30-47.
385. Pettorossi VE, Dutia M, Frondaroli A, Dieni C, Grassi S. Long-term potentiation and depression after unilateral labyrinthectomy in the medial vestibular nucleus of rats. Acta Otolaryngol. 2003;123:182-6.
386. Grassi S, Frondaroli A, Dieni C, Dutia MB, Pettorossi VE. Neurosteroid modulation of neuronal excitability and synaptic transmission in the rat medial vestibular nuclei. Eur J Neurosci. 2007;26:23-32.
387. Vyas A, Mitra R, Shankaranarayana Rao BS, Chattarji S. Chronic stress induces contrasting patterns of dendritic remodelling in hippocampal and amygdaloid neurons. J Neurosci. 2002;22:6810-8.
388. Maroun M, Richter-Levin G. Exposure to acute stress blocks the induction of long-term potentiation of the amy-gdala-prefrontal cortex pathway in vivo. J Neurosci. 2003; 23:4406-9.
389. Conrad CD, LeDoux JE, Magarinos AM, McEwen BS. Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav Neurosci. 1999;113:902-13.
390. Sapolsky RM. Stress and plasticity in the limbic system. Neurochem Res. 2003;28:1735-42.
391. Brown ES, Woolston DJ, Frol AB. Amygdala volume in patients receiving chronic corticosteroid therapy. Biol Psychiatry. 2008;63:705-9.
392. Wood GE, Young LT, Reagan LP, McEwen BS. Acute and chronic restraint stress alter the incidence of social conflict in male rats. Horm Behav. 2003;43:205-13.
393. Lupien SJ, Maheu F, Tu M, Fiocco A, Schramek TE. The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition . Brain Cogn. 2007;65:209-37.
394. Lederbogen F, Kirsch P, Haddad L, Streit F, Tost H, Schuch P, et al. City living and urban upbringing affect neural social stress processing in humans. Nature. 2011; 474:498-501.
395. Dal-Zotto S, Marti O, Armario A. Glucocorticoids are involved in the long-term effects of a single immobilization stress on the hypothalamic- pituitary-adrenal axis. Psychone-uroendocrinology. 2003;28:992-1009.
396. Roozendaal B, Barsegyan A, Lee S. Adrenal stress hormones, amygdala activation, and memory for emotionally arousing experiences. Prog Brain Res. 2008;167:79-97.
397. An B, Hong I, Choi S. Long-term neural correlates of reversible fear learning in the lateral amygdala. J Neurosci. 2012;32:16845-56.
398. Cameron SA, Dutia MB. Lesion-induced plasticity in rat vestibular nucleus neurons dependent on glucocorticoid receptor activation . J Physiol. 1999;518:151-8.
399. Joels M, Karst H, Krugers HJ, Lucassen PJ. Chronic stress: implications for neuronal morphology, function and neuro-genesis. Front Neuroendocrinol. 2007;28:72-96.
400. Sandi C, Pinelo-Nava MT. Stress and memory: behavioural effects and neurobiological mechanisms. Neural Plast. 2007;2007:78970.
401. Wright RL, Lightner EN, Harman JS, Meijer OC, Conrad CD. Attenuating corticosterone levels on the day of memory assessment prevents chronic stress-induced impairments in spatial memory. Eur J Neurosci. 2006;24:595-605.
402. Andersson G, Yardley L. Time-series analysis of the relationship between dizziness and stress. Scand J Psychol. 2000; 41:49-54.
403. Falkenius-Schmidt K, Rydmarker S, Horner KC. Hyperpro-lactinaemia in some Meniere's disease patients even in the absence of incapacitating vertigo. Hear Res. 2005; 203:154-8.
404. Goebel JA. Management options for acute versus chronic vertigo. Otolaryngol Clin North Am. 2000;33:483-93.
405. Baloh RW. Approach to the dizzy patient. Baillieres Clin Neurol. 1994;3:453-65.
406. Biswas A. An introduction to neurotology. Bhalani Publishing House. Mumbai - 2nd ed. J Indian Soc Otol. 2006; 166-193.
407. Strupp M, Thurtell MJ, Shaikh AG, Brandt T, Zee DS, Leigh RJ. Pharmacotherapy of vestibular and ocular motor disorders, including nystagmus. J Neurol. 2011; 258:1207-22.
408. Huppert D, Strupp M, Muckter H, Brandt T. Which medication do I need to manage dizzy patients? Acta Otolaryngol. 2011;131:228-1.
409. Zajonc TP, Roland PS. Vertigo and motion sickness. Part II: Pharmacologic treatment. Ear Nose Throat J. 2006;85: 25-35.
410. Yacovino DA, Hain TC. The pharmacology of vestibular disorders. Rev Neurol. 2004;39:381-7.
411. Tusa RJ. Vertigo. Neurol Clin. 2001;19:23-55.
412. Baloh RW. Vertigo. Lancet. 1998;352:1841-6.
413. Zee DS. Perspectives on the pharmacotherapy of vertigo. Arch Otolaryngol. 1985;111:609-12.
414. Swartz R, Longwell P. Treatment of vertigo. Am Fam Physician. 2005;71:1115-22.
415. Baloh RW. Benign positional vertigo. In: Baloh RW, Halmagyi GM (editors). Disorders of the vestibular system. New York: Oxford University Press; 1996. pp. 328-39.
416. Hain TC, Yacovino D. Pharmacologic treatment of persons with dizziness. Neurol Clin. 2005;23:831-53.
417. Rascol O, Hain TC, Brefel C, Benazet M, Clanet M, Montastruc JL. Antivertigo medications and drug-induced vertigo: a pharmacological review. Drugs. 1995;50:777-91.
418. Brandt T, Zwergal A, Strupp M. Medical treatment of vestibular disorders. Expert Opin Pharmacother. 2009; 10:1537-48.
419. Redon C, Lopez C, Bernard-Demanze L, Dumitrescu M, Magnan J, Lacour M, et al. Betahistine treatment improves the recovery of static symptoms in patients with unilateral vestibular loss . J Clin Pharmacol. 2011;51:538-48.
420. Lacour M, van de Heyning PH, Novotny M, Tighilet B. Betahistine in the treatment of Meniere's disease. Neuropsy- chiatr Dis Treat. 2007;3:429-40.
421. Tighilet B, Trottier S, Mourre C, Lacour M. Changes in the histaminergic system during vestibular compensation in the cat. J Physiol. 2006;573:723-39.
422. Lezius F, Adrion C, Mansmann U, Jahn K, Strupp M. High-dosage betahistine dihydrochloride between 288 and 480 mg/day in patients with severe Meniere's disease: a case series. Eur Arch Otorhinolaryngol. 2011;268: 1237-40.
423. Smith PF, Darlington CL. Can vestibular compensation be enhanced by drug treatment? A review of recent evidence. J Vestib Res. 1994;4:169-79.
424. Winnicka K, Tomasiak M, Bielawska A. Piracetam: an old drug with novel properties? Acta Pol Pharm. 2005;62: 405-9.
425. Krishna BA, Kirtane MV, Sangeeta T, Gopinath G. Pre and post betahistine therapy 99m Tc - HMPAO brain spect studies in patients with vertigo. Neurol India. 2000;48:255-9.
426. Leuner K, Kurz C, Guidetti G, Orgogozo JM, Muller WE. Improved mitochondrial function in brain aging and Alzheimer disease: the new mechanism of action of the old metabolic enhancer piracetam. Front Neurosci. 2010;Sep 7;4. doi:pii: 44.10.3389/fnins.2010.00044.PMID:20877425.
427. Winblad B. Piracetam: a review of pharmacological properties and clinical uses. CNS Drug Rev. 2005;11: 169-82.
428. Yang YL, Su YW, Ng MC, Chang CL, Lu KT. Extract of Ginkgo biloba EGb 761 facilitates fear conditioning measured by fear-potentiated startle. Neurosci Lett. 2005; 383:145-50.
429. Chavez H, Vega R, Valli P, Mira E, Benvenuti C, Guth PS, et al. Action mechanism of betahistine in the vestibular end organs. Acta Otorhinolaryngol Ital. 2001; 21:8-15.
430. Lacour M, Sterkers O. Histamine and betahistine in the treatment of vertigo: elucidation of mechanisms of action. CNS Drugs. 2001;15:853-70.
431. Kurz C, Ungerer I, Lipka U, Kirr S, Schutt T, Eckert A, et al. The metabolic enhancer piracetam ameliorates the impairment of mitochondrial function and neurite outgrowth induced by beta-amyloid peptide. Br J Pharmacol. 2010;160:246-57.
432. Muller WE, Eckert GP, Eckert A. Piracetam: novelty in a unique mode of action. Pharmacopsychiatry. 1999;2-9.
433. Peuvot J, Schanck A, Deleers M, Brasseur R. Piracetam-induced changes to membrane physical properties. A combined approach by 31P nuclear magnetic resonance and conformational analysis. Biochem Pharmacol. 1995; 50:1129-34.
434. Horak FB. Postural compensation for vestibular loss and implications for rehabilitation. Restor Neurol Neurosci. 2010;28:57-68.
435. Howe TE, Rochester L, Jackson A, Banks PM, Blair VA. Exercise for improving balance in older people. Cochrane Database Syst Rev 2007;4:CD004963.
436. Jung JY, Kim JS, Chung PS, Woo SH, Rhee CK. Effect of vestibular rehabilitation on dizziness in the elderly. Am J Otolaryngol. 2009;30:295-9.
437. Clendaniel RA, Tucci DL. Vestibular rehabilitation strategies in Meniere's disease. Otolaryngol Clin North Am. 1997; 30:1145-58.
438. Yardley L. Overview of psychologic effects of chronic dizziness and balance disorders. Otolaryngol Clin North Am. 2000;33:603-16.
439. Vlaeyen JW, Kole-Snijders AM, Boeren RG, Van Eek H. Fear of movement/(re)injury in chronic low back pain and its relation to behavioural performance. Pain. 1995; 62:363-72.
440. Vlaeyen JW, Haazen IW, Schuerman JA, Kole-Snijders AM, Van Eek H. Behavioural rehabilitation of chronic low back pain: comparison of an operant treatment, an operant-cognitive treatment and an operant-respondent treatment. Br J Clin Psychol . 1995;34:95-118.
441. Spence M, Moss-Morris R, Chalder T. The Behavioural Responses to Illness Questionnaire (BRIQ): a new predictive measure of medically unexplained symptoms following acute infection. Psychol Med. 2005;35:583-93.