Age differences in the neural systems supporting human allocentric spatial navigation

Neurobiology of Aging

Volumn 27, Issue 7, 2006, Pages 965-972

  Moffat, Scott D ^a,b   Elkins, Wendy ^a   Resnick, Susan M ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Cognitive aging; fMRI; Hippocampus; Human; Navigation; Parahippocampal gyrus; Retro splenial cortex; Spatial memory

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN DEPTH STIMULATION; CEREBELLUM; CINGULATE GYRUS; CONTROLLED STUDY; FEMALE; FRONTAL LOBE; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; MALE; NERVE CELL NETWORK; PARIETAL LOBE; PRIORITY JOURNAL; SPATIAL MEMORY; SUBICULUM; VIRTUAL REALITY;

ADULT; AGED; AGING; BRAIN; BRAIN MAPPING; COGNITION; FEMALE; FUNCTIONAL LATERALITY; GYRUS CINGULI; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY DISORDERS; MIDDLE AGED; NERVE NET; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; ORIENTATION; PARIETAL LOBE; SPACE PERCEPTION;

EID: 33646504470     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2005.05.011     Document Type: Article

References (37)

1. Aguirre G.K., Detre J.A., Alsop D.C., and D'Esposito M. The parahippocampus subserves topographical learning in man. Cereb Cortex 6 (1996) 823-829
2. Barnes C.A., McNaughton B.L., and O'Keefe J. Loss of place specificity in hippocampal complex spike cells of senescent rat. Neurobiol Aging 4 (1983) 113-119
3. Barnes C.A., Suster M.S., Shen J., and McNaughton B.L. Multistability of cognitive maps in the hippocampus of old rats. Nature 388 (1997) 272-275
4. Barrash J. A historical review of topographical disorientation and its neuroanatomical correlates. J Clin Exp Neuropsychol 20 (1998) 807-827
5. Burns P.C. Navigation and mobility of older drivers. J Gerontol Social Sci 54B (1999) S49-S55
6. Bush G., Luu P., and Posner M.I. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4 (2000) 215-222
7. Cabeza R., Grady C.L., Nyberg L., McIntosh A.R., Tulving E., Kapur S., et al. Age-related differences in neural activity during memory encoding and retrieval: a positron emission tomography study. J Neurosci 17 (1997) 391-400
8. Chen L.L., Lin L.H., Green E.J., Barnes C.A., and McNaughton B.L. Head-direction cells in the rat posterior cortex. I. Anatomical distribution and behavioral modulation. Exp Brain Res 101 (1994) 8-23
9. Eichenbaum H. Is the rodent hippocampus just for 'place'?. Curr Opin Neurobiol 6 (1996) 187-195
10. Ekstrom A.D., Kahana M.J., Caplan J.B., Fields T.A., Isham E.A., Newman E.L., et al. Cellular networks underlying human spatial navigation. Nature 425 (2003) 184-188
11. Grady C.L., and Craik F.I. Changes in memory processing with age. Curr Opin Neurobiol 10 (2000) 224-231
12. Grady C.L., McIntosh A.R., and Craik F.I. Age-related differences in the functional connectivity of the hippocampus during memory encoding. Hippocampus 13 (2003) 572-586
13. Gron G., Wunderlich A.P., Spitzer M., Tomczak R., and Riepe M.W. Brain activation during human navigation: gender-different neural networks as substrate of performance. Nat Neurosci 3 (2000) 404-408
14. Gutchess A.H., Welsh R.C., Hedden T., Bangert A., Minear M., Liu L.L., et al. Aging and the neural correlates of successful picture encoding: frontal activations compensate for decreased medial-temporal activity. J Cogn Neurosci 17 (2005) 84-96
15. Jack Jr. C.R., Petersen R.C., Xu Y., O'Brien P.C., Smith G.E., Ivnik R.J., et al. Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease. Neurology 51 (1998) 993-999
16. Katayama K., Takahashi N., Ogawara K., and Hattori T. Pure topographical disorientation due to right posterior cingulate lesion. Cortex 35 (1999) 279-282
17. Kirasic K.C., Allen G.L., and Haggerty D. Age-related differences in adults' macrospatial cognitive processes. Exp Aging Res 18 (1992) 33-39
18. Klein D.A., Steinberg M., Galik E., Steele C., Sheppard J.M., Warren A., et al. Wandering behaviour in community-residing persons with dementia. Int J Geriatr Psychiatry 14 (1999) 272-279
19. Knierim J.J., Kudrimoti H.S., and McNaughton B.L. Place cells, head direction cells, and the learning of landmark stability. J Neurosci 15 (1995) 1648-1659
20. Maguire E.A., Burgess N., Donnett J.G., Frackowiak R.S., Frith C.D., and O'Keefe J. Knowing where and getting there: a human navigation network. Science 280 (1998) 921-924
21. Moffat S.D., and Resnick S.M. Effects of age on virtual environment place navigation and allocentric cognitive mapping. Behav Neurosci 116 (2002) 851-859
22. Moffat S.D., Zonderman A.B., and Resnick S.M. Age differences in spatial memory in a virtual environment navigation task. Neurobiol Aging 22 (2001) 787-796
23. Morris R.G., Garrud P., Rawlins J.N., and O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature 297 (1982) 681-683
24. OKeefe J., and Nadel L. The hippocampus as a cognitive map (1978), Oxford University Press, Oxford, UK
25. Paus T., Koski L., Caramanos Z., and Westbury C. Regional differences in the effects of task difficulty and motor output on blood flow response in the human anterior cingulate cortex: a review of 107 PET activation studies. Neuroreport 9 (1998) R37-R47
26. Save E., and Poucet B. Involvement of the hippocampus and associative parietal cortex in the use of proximal and distal landmarks for navigation. Behav Brain Res 109 (2000) 195-206
27. Shen J., Barnes C.A., McNaughton B.L., Skaggs W.E., and Weaver K.L. The effect of aging on experience-dependent plasticity of hippocampal place cells. J Neurosci 17 (1997) 6769-6782
28. Tanila H., Shapiro M., Gallagher M., and Eichenbaum H. Brain aging: changes in the nature of information coding by the hippocampus. J Neurosci 17 (1997) 5155-5166
29. West M.J., Coleman P.D., Flood D.G., and Troncoso J.C. Differential neuronal loss in the hippocampus in normal aging and in patients with Alzheimer disease. Ugeskr Laeger 157 (1995) 3190-3193
30. Wylie D.R., Glover R.G., and Aitchison J.D. Optic flow input to the hippocampal formation from the accessory optic system. J Neurosci 19 (1999) 5514-5527
31. de Leon M.J., Convit A., Wolf O.T., Tarshish C.Y., DeSanti S., Rusinek H., et al. Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-d-glucose/poitron-emission tomography (FDG/PET). Proc Natl Acad Sci USA 98 (2001) 10966-10971
32. Jack Jr. C.R., Petersen R.C., Xu Y.C., O'Brien P.C., Smith G.E., Ivnik R.J., et al. Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment. Neurology 52 (1999) 1397-1403
33. Jack Jr. C.R., Petersen R.C., Xu Y.C., Waring S.C., O'Brien P.C., Tangalos E.G., et al. Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease. Neurology 49 (1997) 786-794
34. Minoshima S., Foster N.L., and Kuhl D.E. Posterior cingulate cortex in Alzheimer's disease. Lancet 344 (1994) 895
35. Reiman E.M., Caselli R.J., Chen K., Alexander G.E., Bandy D., and Frost J. Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: a foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. Proc Natl Acad Sci USA 98 (2001) 3334-3339
36. 18F-FDG PET in the diagnosis of neurodegenerative dementias: comparison with perfusion SPECT and with clinical evaluations lacking nuclear imaging. J Nucl Med 45 (2004) 594-607
37. Small G.W., Ercoli L.M., Silverman D.H., Huang S.C., Komo S., Bookheimer S.Y., et al. Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci USA 97 (2000) 6037-6042