Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells

Molecular Biology of the Cell

Volumn 24, Issue 7, 2013, Pages 1068-1082

  Waheed, Faiza ^a   Dan, Qinghong ^a   Amoozadeh, Yasaman ^a   Zhang, Yuqian ^a   Tanimura, Susumu ^b   Speight, Pam ^a   Kapus, András ^a   Szászi, Katalin ^a  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR H1; GUANOSINE TRIPHOSPHATASE; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; RAC PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EPITHELIUM; KIDNEY TUBULE CELL; MEMBRANE DEPOLARIZATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WOUND HEALING;

ADAM PROTEINS; ANIMALS; BLOTTING, WESTERN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; KIDNEY TUBULES, PROXIMAL; LLC-PK1 CELLS; MATRIX METALLOPROTEINASES; MICROSCOPY, FLUORESCENCE; MUTATION; PHOSPHORYLATION; RAC GTP-BINDING PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RHOA GTP-BINDING PROTEIN; RNA INTERFERENCE; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84875410357     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E12-09-0661     Document Type: Article

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