GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling

Journal of Pathology

Volumn 228, Issue 4, 2012, Pages 575-585

  Cheng, Ibis K C ^a,b   Tsang, Bruce C K ^a   Lai, Keng Po ^a   Ching, Arthur K K ^a   Chan, Anthony W H ^a   To, Ka Fai ^a   Lai, Paul B S ^a   Wong, Nathalie ^a,c  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

EMT; GEF H1; Hepatocellular carcinoma; Oncogene; RhoA

Indexed keywords

ACTIN; ALPHA CATENIN; CYTOKERATIN 18; FIBRONECTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR H1; MYOSIN LIGHT CHAIN 2; NERVE CELL ADHESION MOLECULE; PEPTIDES AND PROTEINS; PLAKOGLOBIN; PROTEIN ROCK1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; MATRIGEL; PROTEIN; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR H1; ARHGEF2 PROTEIN, HUMAN; RHOA PROTEIN, HUMAN; SMALL INTERFERING RNA;

ADULT; ARTICLE; CANCER INVASION; CELL MOTILITY; CELL VIABILITY; DISEASE FREE SURVIVAL; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; ACTIN FILAMENT; ACTIN POLYMERIZATION; CANCER PATIENT; CANCER SURVIVAL; CELL INVASION; CELL MIGRATION; COHORT ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DOWN REGULATION; GENE DOSAGE; GENE OVEREXPRESSION; HUMAN TISSUE; LIVER CARCINOGENESIS; METASTASIS POTENTIAL; MIDDLE AGED; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STRESS FIBER; TUMOR INVASION; UPREGULATION; AGED; CANCER STAGING; CELL MOTION; EPITHELIUM CELL; GENETICS; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; SECONDARY;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PHENOTYPE; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84871237402     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4084     Document Type: Article

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