Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy

Journal of the American Society of Nephrology

Volumn 17, Issue 6, 2006, Pages 1615-1623

  Chen, Jianchun ^a   Chen, Jian Kang ^a   Neilson, Eric G ^a   Harris, Raymond C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; BATIMASTAT; COMPLEMENTARY DNA; CRM 197; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HEPARIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR INHIBITOR; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; METALLOPROTEINASE INHIBITOR; PHENANTHROLINE DERIVATIVE; PROTEIN S6; PROTEIN TYROSINE KINASE INHIBITOR; RAPAMYCIN; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPERPLASIA; CONTROLLED STUDY; KIDNEY EPITHELIUM; KIDNEY HYPERTROPHY; KIDNEY PROXIMAL TUBULE; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; TRANSACTIVATION;

EID: 33646932374     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2005111163     Document Type: Article

References (47)

1. Hostetter TH: Progression of renal disease and renal hypertrophy. Annu Rev Physiol 57: 263-278, 1995
2. Preisig PA: Renal hypertrophy and hyperplasia. In: The Kidney, 3rd Ed., Vol. 1, edited by Selden DW, Giebisch G, Philadelphia, Lippincott Williams & Wilkins, 2000, pp 727-748
3. Brenner BM: Remission of renal disease: recounting the challenge, acquiring the goal. J Clin Invest 110: 1753-1758, 2002
4. Fine L: The biology of renal hypertrophy. Kidney Int 29: 619-634, 1986
5. Chen JK, Chen J, Neilson EG, Harris RC: Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. J Am Soc Nephrol 16: 1384-1391, 2005
6. Wolf G, Mueller E, Stahl RA, Ziyadeh FN: Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-beta. J Clin Invest 92: 1366-1372, 1993
7. Zhang SL, To C, Chen X, Filep JG, Tang SS, Ingelfinger JR, Carriere S, Chan JS: Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells. Exp Nephrol 9: 109-117, 2001
8. Bakris GL: Angiotensin-converting enzyme inhibitors and progression of diabetic nephropathy. Ann Intern Med 118: 643-644, 1993
9. Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, Ritz E, Atkins RC, Rohde R, Raz I: Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 345: 851-860, 2001
10. Siragy HM: AT1 and AT2 receptor in the kidney: Role in health and disease. Semin Nephrol 24: 93-100, 2004
11. Eguchi S, Inagami T: Signal transduction of angiotensin II type 1 receptor through receptor tyrosine kinase. Regul Pept 91: 13-20, 2000
12. Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, Ullrich A: EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402: 884-888, 1999
13. Mujais SK, Kauffman S, Katz AI: Angiotensin II binding sites in individual segments of the rat nephron. J Clin Invest 77: 315-318, 1986
14. Breyer MD, Redha R, Breyer JA: Segmental distribution of epidermal growth factor binding sites in rabbit nephron. Am J Physiol 259: F553-F558, 1990
15. Amsler K, Cook JS: Development of Na+-dependent hexose transport in a cultured line of porcine kidney cells. Am J Physiol 242: C94-C101, 1982
16. Wolf G, Zahner G, Mondorf U, Schoeppe W, Stahl RA: Angiotensin II stimulates cellular hypertrophy of LLC-PK1 cells through the AT1 receptor. Nephrol Dial Transplant 8: 128-133, 1993
17. Chen JK, Falck JR, Reddy KM, Capdevila J, Harris RC: Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells. J Biol Chem 273: 29254-29261, 1998
18. Chen JK, Wang DW, Falck JR, Capdevila J, Harris RC: Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor. J Biol Chem 274: 4764-4769, 1999
19. Chen JK, Capdevila J, Harris RC: Overexpression of C-terminal Src kinase blocks 14,15-epoxyeicosatrienoic acid-induced tyrosine phosphorylation and mitogenesis. J Biol Chem 275: 13789-13792, 2000
20. Chen JK, Capdevila J, Harris RC: Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells. Proc Natl Acad Sci U S A 99: 6029-6034, 2002
21. Burns KD, Harris RC: Signaling and growth responses of LLC-PK1/C14 cells transfected with the rabbit AT1 ANG II receptor. Am J Physiol 268: C925-C935, 1995
22. Chen JK, Zimpelmann J, Harris RC, Burns KD: Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells. Am J Physiol Renal Physiol 280: F980-F988, 2001
23. Sakai M, Zhang M, Homma T, Garrick B, Abraham JA, McKanna JA, Harris RC: Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute renal injury. Isolation and localization of bioactive molecules. J Clin Invest 99: 2128-2138, 1997
24. Harris RC: Regulation of S6 kinase activity in renal proximal tubule. Am J Physiol 263: F127-F134, 1992
25. Naglich JG, Metherall JE, Russell DW, Eidels L: Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor. Cell 69: 1051-1061, 1992
26. Mitamura T, Higashiyama S, Taniguchi N, Klagsbrun M, Mekada E: Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem 270: 1015-1019, 1995
27. Mitamura T, Umata T, Nakano F, Shishido Y, Toyoda T, Itai A, Kimura H, Mekada E: Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis. J Biol Chem 272: 27084-27090, 1997
28. Schmelzle T, Hall MN: TOR, a central controller of cell growth. Cell 103: 253-262, 2000
29. Fingar DC, Salama S, Tsou C, Harlow E, Blenis J: Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev 16: 1472-1487, 2002
30. Brunn GJ, Hudson CC, Sekulic A, Williams JM, Hosoi H, Houghton PJ, Lawrence JC Jr, Abraham RT: Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin. Science 277: 99-101, 1997
31. Gingras AC, Raught B, Sonenberg N: mTOR signaling to translation. Curr Top Microbiol Immunol 279: 169-197, 2004
32. Shima H, Pende M, Chen Y, Fumagalli S, Thomas G, Kozma SC: Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. EMBO J 17: 6649-6659, 1998
33. Wolf G, Neilson EG: Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells. Am J Physiol 259: F768-F777, 1990
34. Franch HA, Shay JW, Alpern RJ, Preisig PA: Involvement of pRB family in TGF beta-dependent epithelial cell hypertrophy. J Cell Biol 129: 245-254, 1995
35. Liu B, Preisig P: TGF-beta1-mediated hypertrophy involves inhibiting pRB phosphorylation by blocking activation of cyclin E kinase. Am J Physiol 277: F186-F194, 1999
36. Huang HC, Preisig PA: G1 kinases and transforming growth factor-beta signaling are associated with a growth pattern switch in diabetes-induced renal growth. Kidney Int 58: 162-172, 2000
37. Bell SP, Dutta A: DNA replication in eukaryotic cells. Annu Rev Biochem 71: 333-374, 2002
38. Hannken T, Schroeder R, Stahl RA, Wolf G: Angiotensin II-mediated expression of p27Kip1 and induction of cellular hypertrophy in renal tubular cells depend on the generation of oxygen radicals. Kidney Int 54: 1923-1933, 1998
39. Terada Y, Inoshita S, Nakashima O, Tamamori M, Ito H, Kuwahara M, Sasaki S, Marumo F: Cell cycle inhibitors (p27Kip1 and p21CIP1) cause hypertrophy in LLC-PK1 cells. Kidney Int 56: 494-501, 1999
40. Wolf G, Wenzel U, Hannken T, Stahl RA: Angiotensin II induces p27(Kip1) expression in renal tubules in vivo: Role of reactive oxygen species. J Mol Med 79: 382-389, 2001
41. Monkawa T, Hiromura K, Wolf G, Shankland SJ: The hypertrophic effect of transforming growth factor-beta is reduced in the absence of cyclin-dependent kinase-inhibitors p21 and p27. J Am Soc Nephrol 13: 1172-1178, 2002
42. Gschwind A, Zwick E, Prenzel N, Leserer M, Ullrich A: Cell communication networks: Epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission. Oncogene 20: 1594-1600, 2001
43. Harris RC, Chung E, Coffey RJ: EGF receptor ligands. Exp Cell Res 284: 2-13, 2003
44. Salido EC, Yen PH, Shapiro LJ, Fisher DA, Barajas L: In situ hybridization of prepro-epidermal growth factor mRNA in the mouse kidney. Am J Physiol 256: F632-F638, 1989
45. Suzuki M, Raab G, Moses MA, Fernandez CA, Klagsbrun M: Matrix metalloproteinase-3 releases active heparin-binding EGF-like growth factor by cleavage at a specific juxtamembrane site. J Biol Chem 272: 31730-31737, 1997
46. Lafayette RA, Mayer G, Park SK, Meyer TW: Angiotensin II receptor blockade limits glomerular injury in rats with reduced renal mass. J Clin Invest 90: 766-771, 1992
47. Lautrette A, Li S, Alili R, Sunnarborg SW, Burtin M, Lee DC, Friedlander G, Terzi F: Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: A new therapeutic approach. Nat Med 11: 867-874, 2005