Spectrophotometric determination of de novo hemozoin/β-hematin formation in an in vitro assay

Analytical Biochemistry

Volumn 325, Issue 1, 2004, Pages 85-91

  Tripathi, Abhai K ^a   Khan, Shabana I ^a   Walker, Larry A ^a,b   Tekwani, Babu L ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Hemozoin; Malaria; Plasmodium falciparum; Hematin

Indexed keywords

AGGREGATES; BIOCHEMISTRY; DISEASES; INFRARED SPECTROSCOPY; PELLETIZING; PORPHYRINS; SPECTROPHOTOMETERS; SPECTROPHOTOMETRY;

ACCURATE QUANTIFICATIONS; BICARBONATE SOLUTION; HEMOZOIN; MALARIA; MOLECULAR MECHANISM; PLASMODIUM FALCIPARUM; SPECTROPHOTOMETRIC ASSAYS; SPECTROPHOTOMETRIC DETERMINATION;

FATTY ACIDS;

ANTIMALARIAL AGENT; BETA HEMATIN; HEMATIN; HEME DERIVATIVE; HEMOZOIN; INITIATION FACTOR; LIPID; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BIOASSAY; BIOAVAILABILITY; BIOFILTRATION; CATALYSIS; CATALYST; CELL LYSATE; CONTROLLED STUDY; IN VITRO STUDY; INFRARED SPECTROSCOPY; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DETERMINATION; SCREENING TEST; SPECTROPHOTOMETRY; VALIDATION PROCESS;

PLASMODIUM FALCIPARUM;

EID: 0346728681     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2003.10.016     Document Type: Article

References (31)

1. Goldberg D.E., Slater A. The pathway of haemoglobin degradation in malaria. Parasitol. Today. 8:1992;280-283.
2. Francis S.E., Sullivan D.J. Jr., Goldberg D.E. Hemoglobin metabolism in the malaria parasite Plasmodium falciparum. Annu. Rev. Microbiol. 51:1997;97-123.
3. Gluzman I.V., Francis S.E., Oksman A., Smith C.E., Duffin K.L., Goldberg D.E. Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway. J. Clin. Invest. 93:1994;1602-1608.
4. Coombs G.H., Goldberg D.E., Klembs M., Berry C., Kay J., Mottram J.C. Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets. Trends Parasitol. 17:2001;532-537.
5. Fitch C.D., Chevli R., Banyal H.S. Lysis of Plasmodium falciparum by chloroquine ferriprotoporphyrin IX complex. Antimicrob. Agents Chemother. 21:1982;819-822.
6. Fitch C.D., Kanjananggulupan P. The state of ferriprotoporphyrin IX in malaria pigment. J. Biol. Chem. 262:1987;15552-15555.
7. Rosenthal P.J., Sijwali P.S., Singh A., Shenai B.R. Cysteine proteases of malaria parasites: targets for chemotherapy. Curr. Pharm. Des. 8:2002;1659-1672.
8. Slater A.F., Swiggard W.J., Orton B.R., Flitter W.D., Goldberg D.E., Cerami A., Henderson G.B. An iron carboxylate bond links the heme units of malaria pigment. Proc. Natl. Acad. Sci. USA. 88:1991;325-329.
9. Pagola S., Stephens P.W., Bohle D.S., Kosar A.D., Madsen S.K. The structure of malaria pigment β-hematin. Nature. 404:2000;307-310.
10. Tripathi A.K., Tekwani B.L. Formation of β-hematin in malaria parasite: lipids edge over the proteins as possible mediator. J. Parasit. Dis. 23:2000;61-70.
11. Sullivan D.J. Theories on malaria pigment formation and quinoline action. Int. J. Parasitol. 32:2002;1645-1653.
12. Egan T.J. Physico-chemical aspects of hemozoin (malaria pigment) structure and formation. J. Inorg. Biochem. 91:2002;19-26.
13. Loria P., Miller S., Foley M., Tilley L. Inhibition of the peroxidative degradation of heme as the basis of action of chloroquine and other quinoline antimalarials. Biochem. J. 339:1999;363-370.
14. Ginsburg H., Famin O., Zhang J., Krugliak M. Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action. Biochem. Pharmacol. 56:1998;1305-1313.
15. Hempelmann E., Motta C., Huges R., Ward S.A., Bray P.G. Plasmodium falciparum, sacrificing membrane to grow crystals. Trends Parasitol. 19:2003;23-26.
16. Dorn A., Vippagunta S.R., Matile H., Bubendorf A., Vennerstrom J.L., Ridley R.G. A comparison of several ways to promote hematin (heme) polymerization and an assessment of its initiation in vitro. Biochem. Pharmacol. 55:1998;737-747.
17. Sullivan A.D., Havat I., Meshnick S.R. Patterns of hemozoin accumulation in tissue. Parasitology. 112:1996;285-294.
18. Berger B.J., Bendrat K., Cerami A. High performance liquid chromatographic analysis of biological and chemical β-hematin formation. Anal. Biochem. 231:1995;151-156.
19. Pandey A.V., Singh N., Tekwani B.L., Puri S.K., Chauhan V.S. Assay of β-hematin formation by malaria parasite. J. Pharmaceut. Biomed. Anal. 20:1999;203-208.
20. Egan T.J., Ross D.C., Adams P.A. Quinoline antimalarial drugs inhibit spontaneous formation of β-hematin (malaria pigment). FEBS Lett. 352:1996;54-57.
21. Ignatushchenko M.V., Winter R.W., Bachinger H.P., Hinrichs D.J., Riscoe M.K. Xanthones as antimalarial agents; studies of a possible mode of action. FEBS Lett. 409:1997;67-73.
22. Egan T.J., Mavuso W.W., Ncokazi K.K. The mechanism of β-hematin formation in acetate solution parallels between hemozoin formation and biomineralization process. Biochemistry. 40:2001;204-213.
23. Tripathi A.K., Garg S.K., Tekwani B.L. A physiochemical mechanism of hemozoin formation (β-hematin) synthesis by malaria parasite. Biochem. Biophys. Res. Commun. 290:2002;595-601.
24. Pandey A.V., Tekwani B.L. Formation of malaria pigment/β-hematin under physiological conditions is not spontaneous. FEBS Lett. 393:1996;189-192.
25. Trager W., Jenson J.B. Human malaria parasites in continuous culture. Science. 193:1976;673-675.
26. Tripathi A.K., Gupta A., Garg S.K., Tekwani B.L. In vitro beta-hematin formation assays with plasma of mice infected with Plasmodium yoelii and other parasite preparations: comparative inhibition with quinoline and endoperoxide antimalarials. Life Sci. 69:2001;2725-2733.
27. Fitch C.D., Cai D.J., Chen Y.F., Shoemaker J.D. Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria. Biochem. Biophys. Acta. 1454:1999;31-37.
28. Pandey A.V., Tekwani B.L., Pandey V.C. Characterization of hemozoin from liver and spleen of mice infected with Plasmodium yoelii. Biomed. Res. 16:1994;115-120.
29. Ignatushchenko M.V., Winter R.W., Riscoe M.K. Xanthones as antimalarial agents: stage specificity. Am. J. Trop. Med. Hyg. 62:2000;77-81.
30. Kurosawa Y., Dorn A., Kitsuji-Shirane M., Shimada H., Satoh T., Matile H., Hofheinz W., Masciadri R., Kansy M., Ridley R.G. Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores. Antimicrob. Agents Chemother. 44:2000;2638-2644.
31. Deharo E., Garcia R.N., Oporto P., Gimenez A., Sauvain M., Jullian V., Ginsburg H. A non-radiolabeled ferriprotoporphyrin IX biomineralisation inhibition test for high throughput screening of antimalarial compounds. Exp. Parasitol. 100:2002;252-256.