Design and synthesis of new antimalarial agents from 4-aminoquinoline

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 6, 2005, Pages 2157-2165

  Solomon, V Raja ^a   Puri, Sunil K ^a   Srivastava, Kumkum ^a   Katti, S B ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

4 Aminoquinoline; Antimalarial; Heam binding

Indexed keywords

4 AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT; CHLOROQUINE; HEMATIN; HEME; N 1 (7 CHLOROQUINOLIN 4 YL)BUTANE 1,3 DIAMINE; N 1 (7 CHLOROQUINOLIN 4 YL)ETHANE 1,2 DIAMINE; N 1 (7 CHLOROQUINOLIN 4 YL)PROPANE 1,3 DIAMINE; N 2 (7 CHLOROQUINOLIN 4 YL)PROPANE 1,2 DIAMINE; N [2 (7 CHLOROQUINOLIN 4 YLAMINO)ETHYL] N',N',N'',N'' TETRAMETHYLGUANIDINE HEXAFLUOROPHOSPHATE; N [2 (7 CHLOROQUINOLIN 4 YLAMINO)ETHYL]GUANIDINE; N [2 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL] N',N',N'',N'' TETRAMETHYLGUANIDINE HEXAFLUOROPHOSPHATE; N [2 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL]GUANIDINE; N [3 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL] N',N',N'',N'' TETRAMETHYLGUANIDINE HEXAFLUOROPHOSPHATE; N [3 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL]GUANIDINE; N [4 (7 CHLOROQUINOLIN 4 YLAMINO)BUTYL] N',N',N'',N'' TETRAMETHYLGUANIDINE HEXAFLUOROPHOSPHATE; N [4 (7 CHLOROQUINOLIN 4 YLAMINO)BUTYL]GUANIDINE; N,N 1 BIS(TERT BUTOXYCARBONYL) N 11 [2 (7 CHLOROQUINOLIN 4 YLAMINO)ETHYL]GUANIDINE; N,N 1 BIS(TERT BUTOXYCARBONYL) N 11 [2 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL]GUANIDINE; N,N 1 BIS(TERT BUTOXYCARBONYL) N 11 [3 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL]GUANIDINE; N,N 1 BIS(TERT BUTOXYCARBONYL) N 11 [4 (7 CHLOROQUINOLIN 4 YLAMINO)BUTYL]GUANIDINE; UNCLASSIFIED DRUG; [2 (7 CHLOROQUINOLIN 4 YLAMINO)ETHYL]CARBAMIC ACID TERT BUTYL ESTER; [2 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL]CARBAMIC ACID TERT BUTYL ESTER; [3 (7 CHLOROQUINOLIN 4 YLAMINO)PROPYL]CARBAMIC ACID TERT BUTYL ESTER; [4 (7 CHLOROQUINOLIN 4 YLAMINO)BUTYL]CARBAMIC ACID TERT BUTYL ESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 13844313380     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.12.051     Document Type: Article

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