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Volumn 297, Issue , 2013, Pages 84-90

Transcription factors that control inner ear development and their potential for transdifferentiation and reprogramming

Author keywords

[No Author keywords available]

Indexed keywords

NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATOH1; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR DLX6; TRANSCRIPTION FACTOR EYA1; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR HMX2; TRANSCRIPTION FACTOR HMX3; TRANSCRIPTION FACTOR OTX1; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX2; TRANSCRIPTION FACTOR PAX8; TRANSCRIPTION FACTOR SIX1; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR TBX1; UNCLASSIFIED DRUG;

EID: 84875378866     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2012.11.001     Document Type: Review
Times cited : (21)

References (86)
  • 1
    • 84860745450 scopus 로고    scopus 로고
    • EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear
    • Ahmed M., Xu J., Xu P.X. EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. Development (Cambridge, England) 2012.
    • (2012) Development (Cambridge, England)
    • Ahmed, M.1    Xu, J.2    Xu, P.X.3
  • 2
    • 84863011620 scopus 로고    scopus 로고
    • Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2
    • Ahmed M., Wong E.Y., Sun J., Xu J., Wang F., Xu P.X. Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2. Developmental Cell 2012, 22:377-390.
    • (2012) Developmental Cell , vol.22 , pp. 377-390
    • Ahmed, M.1    Wong, E.Y.2    Sun, J.3    Xu, J.4    Wang, F.5    Xu, P.X.6
  • 3
    • 79958077248 scopus 로고    scopus 로고
    • Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa
    • Basch M.L., Ohyama T., Segil N., Groves A.K. Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa. Journal of Neuroscience 2011, 31:8046-8058.
    • (2011) Journal of Neuroscience , vol.31 , pp. 8046-8058
    • Basch, M.L.1    Ohyama, T.2    Segil, N.3    Groves, A.K.4
  • 5
    • 34249103697 scopus 로고    scopus 로고
    • Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear
    • Bok J., Dolson D.K., Hill P., Ruther U., Epstein D.J., Wu D.K. Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear. Development (Cambridge, England) 2007, 134:1713-1722.
    • (2007) Development (Cambridge, England) , vol.134 , pp. 1713-1722
    • Bok, J.1    Dolson, D.K.2    Hill, P.3    Ruther, U.4    Epstein, D.J.5    Wu, D.K.6
  • 6
    • 63349097966 scopus 로고    scopus 로고
    • Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome
    • Bosman E.A., Quint E., Fuchs H., Hrabe de Angelis M., Steel K.P. Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome. Developmental Biology 2009, 328:285-296.
    • (2009) Developmental Biology , vol.328 , pp. 285-296
    • Bosman, E.A.1    Quint, E.2    Fuchs, H.3    Hrabe de Angelis, M.4    Steel, K.P.5
  • 8
    • 40349112978 scopus 로고    scopus 로고
    • Barhl1 regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system
    • Chellappa R., Li S., Pauley S., Jahan I., Jin K., Xiang M. Barhl1 regulatory sequences required for cell-specific gene expression and autoregulation in the inner ear and central nervous system. Molecular and Cellular Biology 2008, 28:1905-1914.
    • (2008) Molecular and Cellular Biology , vol.28 , pp. 1905-1914
    • Chellappa, R.1    Li, S.2    Pauley, S.3    Jahan, I.4    Jin, K.5    Xiang, M.6
  • 9
    • 48549084248 scopus 로고    scopus 로고
    • Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti
    • Chen Z., Montcouquiol M., Calderon R., Jenkins N.A., Copeland N.G., Kelley M.W., Noben-Trauth K. Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti. Journal of Neuroscience 2008, 28:6633-6641.
    • (2008) Journal of Neuroscience , vol.28 , pp. 6633-6641
    • Chen, Z.1    Montcouquiol, M.2    Calderon, R.3    Jenkins, N.A.4    Copeland, N.G.5    Kelley, M.W.6    Noben-Trauth, K.7
  • 11
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • Davis R.L., Weintraub H., Lassar A.B. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 1987, 51:987-1000.
    • (1987) Cell , vol.51 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 12
    • 73549116094 scopus 로고    scopus 로고
    • Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear
    • Deng M., Pan L., Xie X., Gan L. Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear. Developmental Biology 2010, 338:38-49.
    • (2010) Developmental Biology , vol.338 , pp. 38-49
    • Deng, M.1    Pan, L.2    Xie, X.3    Gan, L.4
  • 13
    • 58149477862 scopus 로고    scopus 로고
    • Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti
    • Doetzlhofer A., Basch M.L., Ohyama T., Gessler M., Groves A.K., Segil N. Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Developmental Cell 2009, 16:58-69.
    • (2009) Developmental Cell , vol.16 , pp. 58-69
    • Doetzlhofer, A.1    Basch, M.L.2    Ohyama, T.3    Gessler, M.4    Groves, A.K.5    Segil, N.6
  • 17
    • 16244402634 scopus 로고    scopus 로고
    • Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development
    • Friedman R.A., Makmura L., Biesiada E., Wang X., Keithley E.M. Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development. Mechanisms of Development 2005, 122:625-634.
    • (2005) Mechanisms of Development , vol.122 , pp. 625-634
    • Friedman, R.A.1    Makmura, L.2    Biesiada, E.3    Wang, X.4    Keithley, E.M.5
  • 18
    • 82755182204 scopus 로고    scopus 로고
    • Historical origins of transdifferentiation and reprogramming
    • Graf T. Historical origins of transdifferentiation and reprogramming. Cell Stem Cell 2011, 9:504-516.
    • (2011) Cell Stem Cell , vol.9 , pp. 504-516
    • Graf, T.1
  • 19
    • 52949112282 scopus 로고    scopus 로고
    • Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer
    • Gubbels S.P., Woessner D.W., Mitchell J.C., Ricci A.J., Brigande J.V. Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature 2008, 455:537-541.
    • (2008) Nature , vol.455 , pp. 537-541
    • Gubbels, S.P.1    Woessner, D.W.2    Mitchell, J.C.3    Ricci, A.J.4    Brigande, J.V.5
  • 21
    • 84856620275 scopus 로고    scopus 로고
    • Defects in sensory organ morphogenesis and generation of cochlear hair cells in Gata3-deficient mouse embryos
    • Haugas M., Lillevali K., Salminen M. Defects in sensory organ morphogenesis and generation of cochlear hair cells in Gata3-deficient mouse embryos. Hearing Research 2012, 283:151-161.
    • (2012) Hearing Research , vol.283 , pp. 151-161
    • Haugas, M.1    Lillevali, K.2    Salminen, M.3
  • 22
    • 0034029614 scopus 로고    scopus 로고
    • Autoregulation and multiple enhancers control Math1 expression in the developing nervous system
    • Helms A.W., Abney A.L., Ben-Arie N., Zoghbi H.Y., Johnson J.E. Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development 2000, 127:1185-1196.
    • (2000) Development , vol.127 , pp. 1185-1196
    • Helms, A.W.1    Abney, A.L.2    Ben-Arie, N.3    Zoghbi, H.Y.4    Johnson, J.E.5
  • 25
    • 0034915989 scopus 로고    scopus 로고
    • Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons
    • Huang E.J., Liu W., Fritzsch B., Bianchi L.M., Reichardt L.F., Xiang M. Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development (Cambridge, England) 2001, 128:2421-2432.
    • (2001) Development (Cambridge, England) , vol.128 , pp. 2421-2432
    • Huang, E.J.1    Liu, W.2    Fritzsch, B.3    Bianchi, L.M.4    Reichardt, L.F.5    Xiang, M.6
  • 26
    • 77956607420 scopus 로고    scopus 로고
    • The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear
    • Hurd E.A., Poucher H.K., Cheng K., Raphael Y., Martin D.M. The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear. Development (Cambridge, England) 2010, 137:3139-3150.
    • (2010) Development (Cambridge, England) , vol.137 , pp. 3139-3150
    • Hurd, E.A.1    Poucher, H.K.2    Cheng, K.3    Raphael, Y.4    Martin, D.M.5
  • 28
    • 77955407251 scopus 로고    scopus 로고
    • Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea
    • Jahan I., Pan N., Kersigo J., Fritzsch B. Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea. PloS One 2010, 5:e11661.
    • (2010) PloS One , vol.5
    • Jahan, I.1    Pan, N.2    Kersigo, J.3    Fritzsch, B.4
  • 29
    • 33845865292 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells
    • Jeon S.J., Oshima K., Heller S., Edge A.S. Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells. Molecular and Cellular Neurosciences 2007, 34:59-68.
    • (2007) Molecular and Cellular Neurosciences , vol.34 , pp. 59-68
    • Jeon, S.J.1    Oshima, K.2    Heller, S.3    Edge, A.S.4
  • 30
    • 32544457518 scopus 로고    scopus 로고
    • Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti
    • Jones J.M., Montcouquiol M., Dabdoub A., Woods C., Kelley M.W. Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti. Journal of Neuroscience 2006, 26:550-558.
    • (2006) Journal of Neuroscience , vol.26 , pp. 550-558
    • Jones, J.M.1    Montcouquiol, M.2    Dabdoub, A.3    Woods, C.4    Kelley, M.W.5
  • 31
    • 77956125791 scopus 로고    scopus 로고
    • Id gene regulation and function in the prosensory domains of the chicken inner ear: a link between Bmp signaling and Atoh1
    • Kamaid A., Neves J., Giraldez F. Id gene regulation and function in the prosensory domains of the chicken inner ear: a link between Bmp signaling and Atoh1. Journal of Neuroscience 2010, 30:11426-11434.
    • (2010) Journal of Neuroscience , vol.30 , pp. 11426-11434
    • Kamaid, A.1    Neves, J.2    Giraldez, F.3
  • 33
    • 84860657802 scopus 로고    scopus 로고
    • Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo
    • Kelly M.C., Chang Q., Pan A., Lin X., Chen P. Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo. Journal of Neuroscience 2012, 32:6699-6710.
    • (2012) Journal of Neuroscience , vol.32 , pp. 6699-6710
    • Kelly, M.C.1    Chang, Q.2    Pan, A.3    Lin, X.4    Chen, P.5
  • 42
    • 0036638824 scopus 로고    scopus 로고
    • Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene
    • Li S., Price S.M., Cahill H., Ryugo D.K., Shen M.M., Xiang M. Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene. Development (Cambridge, England) 2002, 129:3523-3532.
    • (2002) Development (Cambridge, England) , vol.129 , pp. 3523-3532
    • Li, S.1    Price, S.M.2    Cahill, H.3    Ryugo, D.K.4    Shen, M.M.5    Xiang, M.6
  • 44
    • 21044442881 scopus 로고    scopus 로고
    • Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling
    • Lin Z., Cantos R., Patente M., Wu D.K. Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling. Development (Cambridge, England) 2005, 132:2309-2318.
    • (2005) Development (Cambridge, England) , vol.132 , pp. 2309-2318
    • Lin, Z.1    Cantos, R.2    Patente, M.3    Wu, D.K.4
  • 47
    • 79960953181 scopus 로고    scopus 로고
    • Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly
    • Lu C.C., Appler J.M., Houseman E.A., Goodrich L.V. Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly. Journal of Neuroscience 2011, 31:10903-10918.
    • (2011) Journal of Neuroscience , vol.31 , pp. 10903-10918
    • Lu, C.C.1    Appler, J.M.2    Houseman, E.A.3    Goodrich, L.V.4
  • 48
    • 0034446983 scopus 로고    scopus 로고
    • Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation
    • Ma Q., Anderson D.J., Fritzsch B. Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation. Journal of the Association for Research in Otolaryngology 2000, 1:129-143.
    • (2000) Journal of the Association for Research in Otolaryngology , vol.1 , pp. 129-143
    • Ma, Q.1    Anderson, D.J.2    Fritzsch, B.3
  • 49
    • 0032032016 scopus 로고    scopus 로고
    • Neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia
    • Ma Q., Chen Z., del Barco Barrantes I., de la Pompa J.L., Anderson D.J. Neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia. Neuron 1998, 20:469-482.
    • (1998) Neuron , vol.20 , pp. 469-482
    • Ma, Q.1    Chen, Z.2    del Barco Barrantes, I.3    de la Pompa, J.L.4    Anderson, D.J.5
  • 53
    • 84865516574 scopus 로고    scopus 로고
    • Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency
    • Mulvaney J., Dabdoub A. Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency. Journal of the Association for Research Otolaryngology 2012.
    • (2012) Journal of the Association for Research Otolaryngology
    • Mulvaney, J.1    Dabdoub, A.2
  • 54
    • 84856103051 scopus 로고    scopus 로고
    • The prosensory function of sox2 in the chicken inner ear relies on the direct regulation of atoh1
    • Neves J., Uchikawa M., Bigas A., Giraldez F. The prosensory function of sox2 in the chicken inner ear relies on the direct regulation of atoh1. PloS One 2012, 7:e30871.
    • (2012) PloS One , vol.7
    • Neves, J.1    Uchikawa, M.2    Bigas, A.3    Giraldez, F.4
  • 55
    • 59449086387 scopus 로고    scopus 로고
    • Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis
    • Nichols D.H., Pauley S., Jahan I., Beisel K.W., Millen K.J., Fritzsch B. Lmx1a is required for segregation of sensory epithelia and normal ear histogenesis and morphogenesis. Cell and Tissue Research 2008, 334:339-358.
    • (2008) Cell and Tissue Research , vol.334 , pp. 339-358
    • Nichols, D.H.1    Pauley, S.2    Jahan, I.3    Beisel, K.W.4    Millen, K.J.5    Fritzsch, B.6
  • 57
    • 77952493569 scopus 로고    scopus 로고
    • Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells
    • Oshima K., Shin K., Diensthuber M., Peng A.W., Ricci A.J., Heller S. Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells. Cell 2010, 141:704-716.
    • (2010) Cell , vol.141 , pp. 704-716
    • Oshima, K.1    Shin, K.2    Diensthuber, M.3    Peng, A.W.4    Ricci, A.J.5    Heller, S.6
  • 60
    • 33748287042 scopus 로고    scopus 로고
    • Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear
    • Pauley S., Lai E., Fritzsch B. Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear. Developmental Dynamics 2006, 235:2470-2482.
    • (2006) Developmental Dynamics , vol.235 , pp. 2470-2482
    • Pauley, S.1    Lai, E.2    Fritzsch, B.3
  • 62
  • 63
    • 38349002582 scopus 로고    scopus 로고
    • Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development
    • Raft S., Koundakjian E.J., Quinones H., Jayasena C.S., Goodrich L.V., Johnson J.E., Segil N., Groves A.K. Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development. Development 2007, 134:4405-4415.
    • (2007) Development , vol.134 , pp. 4405-4415
    • Raft, S.1    Koundakjian, E.J.2    Quinones, H.3    Jayasena, C.S.4    Goodrich, L.V.5    Johnson, J.E.6    Segil, N.7    Groves, A.K.8
  • 64
    • 58149387077 scopus 로고    scopus 로고
    • Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies
    • Reyes J.H., O'Shea K.S., Wys N.L., Velkey J.M., Prieskorn D.M., Wesolowski K., Miller J.M., Altschuler R.A. Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. Journal of Neuroscience 2008, 28:12622-12631.
    • (2008) Journal of Neuroscience , vol.28 , pp. 12622-12631
    • Reyes, J.H.1    O'Shea, K.S.2    Wys, N.L.3    Velkey, J.M.4    Prieskorn, D.M.5    Wesolowski, K.6    Miller, J.M.7    Altschuler, R.A.8
  • 66
    • 33748996524 scopus 로고    scopus 로고
    • Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus
    • Robledo R.F., Lufkin T. Dlx5 and Dlx6 homeobox genes are required for specification of the mammalian vestibular apparatus. Genesis 2006, 44:425-437.
    • (2006) Genesis , vol.44 , pp. 425-437
    • Robledo, R.F.1    Lufkin, T.2
  • 67
    • 36249013594 scopus 로고    scopus 로고
    • BMP4 induction of sensory neurons from human embryonic stem cells and reinnervation of sensory epithelium
    • Shi F., Corrales C.E., Liberman M.C., Edge A.S. BMP4 induction of sensory neurons from human embryonic stem cells and reinnervation of sensory epithelium. The European Journal of Neuroscience 2007, 26:3016-3023.
    • (2007) The European Journal of Neuroscience , vol.26 , pp. 3016-3023
    • Shi, F.1    Corrales, C.E.2    Liberman, M.C.3    Edge, A.S.4
  • 69
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 72
    • 80054726357 scopus 로고    scopus 로고
    • Direct lineage conversions: unnatural but useful?
    • Vierbuchen T., Wernig M. Direct lineage conversions: unnatural but useful?. Nature Biotechnology 2011, 29:892-907.
    • (2011) Nature Biotechnology , vol.29 , pp. 892-907
    • Vierbuchen, T.1    Wernig, M.2
  • 75
    • 4544244485 scopus 로고    scopus 로고
    • Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx
    • Wang W., Grimmer J.F., Van De Water T.R., Lufkin T. Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Developmental Cell 2004, 7:439-453.
    • (2004) Developmental Cell , vol.7 , pp. 439-453
    • Wang, W.1    Grimmer, J.F.2    Van De Water, T.R.3    Lufkin, T.4
  • 76
    • 0031044215 scopus 로고    scopus 로고
    • Viable offspring derived from fetal and adult mammalian cells
    • Wilmut I., Schnieke A.E., McWhir J., Kind A.J., Campbell K.H. Viable offspring derived from fetal and adult mammalian cells. Nature 1997, 385:810-813.
    • (1997) Nature , vol.385 , pp. 810-813
    • Wilmut, I.1    Schnieke, A.E.2    McWhir, J.3    Kind, A.J.4    Campbell, K.H.5
  • 77
    • 13744263559 scopus 로고    scopus 로고
    • Math1 regulates development of the sensory epithelium in the mammalian cochlea
    • Woods C., Montcouquiol M., Kelley M.W. Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nature Neuroscience 2004, 7:1310-1318.
    • (2004) Nature Neuroscience , vol.7 , pp. 1310-1318
    • Woods, C.1    Montcouquiol, M.2    Kelley, M.W.3
  • 78
    • 0031770385 scopus 로고    scopus 로고
    • Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
    • Xiang M., Gao W.Q., Hasson T., Shin J.J. Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development (Cambridge, England) 1998, 125:3935-3946.
    • (1998) Development (Cambridge, England) , vol.125 , pp. 3935-3946
    • Xiang, M.1    Gao, W.Q.2    Hasson, T.3    Shin, J.J.4
  • 79
    • 0032842838 scopus 로고    scopus 로고
    • Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
    • Xu P.X., Adams J., Peters H., Brown M.C., Heaney S., Maas R. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nature Genetics 1999, 23:113-117.
    • (1999) Nature Genetics , vol.23 , pp. 113-117
    • Xu, P.X.1    Adams, J.2    Peters, H.3    Brown, M.C.4    Heaney, S.5    Maas, R.6
  • 80
    • 79955007124 scopus 로고    scopus 로고
    • Rbpj regulates development of prosensory cells in the mammalian inner ear
    • Yamamoto N., Chang W., Kelley M.W. Rbpj regulates development of prosensory cells in the mammalian inner ear. Developmental Biology 2011, 353:367-379.
    • (2011) Developmental Biology , vol.353 , pp. 367-379
    • Yamamoto, N.1    Chang, W.2    Kelley, M.W.3
  • 82
    • 0034127584 scopus 로고    scopus 로고
    • Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
    • Zheng J.L., Gao W.Q. Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nature Neuroscience 2000, 3:580-586.
    • (2000) Nature Neuroscience , vol.3 , pp. 580-586
    • Zheng, J.L.1    Gao, W.Q.2
  • 85
    • 10344262883 scopus 로고    scopus 로고
    • Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes
    • Zou D., Silvius D., Fritzsch B., Xu P.X. Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Development (Cambridge, England) 2004, 131:5561-5572.
    • (2004) Development (Cambridge, England) , vol.131 , pp. 5561-5572
    • Zou, D.1    Silvius, D.2    Fritzsch, B.3    Xu, P.X.4
  • 86
    • 54449095812 scopus 로고    scopus 로고
    • Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear
    • Zou D., Erickson C., Kim E.H., Jin D., Fritzsch B., Xu P.X. Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. Human Molecular Genetics 2008, 17:3340-3356.
    • (2008) Human Molecular Genetics , vol.17 , pp. 3340-3356
    • Zou, D.1    Erickson, C.2    Kim, E.H.3    Jin, D.4    Fritzsch, B.5    Xu, P.X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.