Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti

Journal of Neuroscience

Volumn 28, Issue 26, 2008, Pages 6633-6641

  Chen, Zheng ^a,f   Montcouquiol, Mireille ^a,b   Calderon, Rene ^a   Jenkins, Nancy A ^c,e   Copeland, Neal G ^c,e   Kelley, Matthew W ^a   Noben Trauth, Konrad ^a,d  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b INSTITUT FRANÇOIS MAGENDIE   (France)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Institute of Molecular and Cell Biology ^*  (United States)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cochlea dysplasia; FCS zinc finger; Jackson circler; Jxc1; K lliker's organ; Organ of corti

Indexed keywords

MESSENGER RNA; ZINC FINGER PROTEIN; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; JXC1 PROTEIN, MOUSE; METALLOPROTEIN; NUCLEAR PROTEIN; SOB PROTEIN, DROSOPHILA;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL NUCLEUS; CELLULAR DISTRIBUTION; COCHLEA; CORTI ORGAN; CYTOPLASM; GENE; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; HAIR CELL; HAIR FOLLICLE; INNER EAR; JXC1 GENE; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; RETINA; SENSORY GANGLION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SINE OCULIS BINDING PROTEIN GENE; TRIGEMINUS GANGLION; VERTEBRATE; WILD TYPE; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL LINEAGE; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; MORPHOGENESIS; MOUSE MUTANT; MUTATION; NERVE CELL; NUCLEAR LOCALIZATION SIGNAL; PRENATAL DEVELOPMENT; SPIRAL GANGLION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BODY PATTERNING; CELL DIFFERENTIATION; CELL LINEAGE; COCHLEA; DNA-BINDING PROTEINS; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HAIR CELLS, AUDITORY; METALLOPROTEINS; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MOLECULAR SEQUENCE DATA; MUTATION; NEURONS; NUCLEAR LOCALIZATION SIGNALS; NUCLEAR PROTEINS; ORGAN OF CORTI; RNA, MESSENGER; SPIRAL GANGLION;

EID: 48549084248     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1280-08.2008     Document Type: Article

References (32)

1. Barald KF, Kelley MW (2004) From placode to polarization: new tunes in inner ear development. Development 131:4119-4130.
2. Bermingham-McDonogh O, Oesterle EC, Stone JS, Hume CR, Huynh HM, Hayashi T (2006) Expression of Prox1 during mouse cochlear development. J Comp Neurol 496:172-186.
3. Brown SD, Hardisty-Hughes RE, Mburu P (2008) Quiet as a mouse: dissecting the molecular and genetic basis of hearing. Nat Rev Genet 9:277-290.
4. Calderon A, Derr A, Stagner BB, Johnson KR, Martin G, Noben-Trauth K (2006) Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse. Hear Res 221:44-58.
5. Chen P, Johnson JE, Zoghbi HY, Segil N (2002) The role of Math1 in inner ear development: uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 129:2495-2505.
6. Curtin JA, Quint E, Tsipouri V, Arkell RM, Cattanach B, Copp AJ, Henderson DJ, Spurr N, Stanier P, Fisher EM, Nolan PM, Steel KP, Brown SD, Gray IC, Murdoch JN (2003) Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr Biol 13:1129-1133.
7. Frolenkov GI, Belyantseva IA, Friedman TB, Griffith AJ (2004) Genetic insights into the morphogenesis of inner ear hair cells. Nat Rev Genet 5:489-498.
8. Jones SM, Johnson KR, Yu H, Erway LC, Alagramam KN, Pollak N, Jones TA (2005) A quantitative survey of gravity receptor function in mutant mouse strains. J Assoc Res Otolaryngol 6:297-310.
9. Kelley MW (2006) Regulation of cell fate in the sensory epithelia of the inner ear. Nat Rev Neurosci 7:837-849.
10. Kenyon KL, Li DJ, Clouser C, Tran S, Pignoni F (2005) Fly SIX-type homeo-domain proteins Sine oculis and Optix partner with different cofactors during eye development. Dev Dyn 234:497-504.
11. Lund AH, van Lohuizen M (2004) Polycomb complexes and silencing mechanisms. Curr Opin Cell Biol 16:239-246.
12. Ma Q, Anderson DJ, Fritzsch B (2000) Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation. J Assoc Res Otolaryngol 1:129-143.
13. Martin P, Swanson GJ (1993) Descriptive and experimental analysis of the epithelial remodellings that control semicircular canal formation in the developing mouse inner ear. Dev Biol 159:549-558.
14. Martynoga B, Morrison H, Price DJ, Mason JO (2005) Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis. Dev Biol 283:113-127.
15. Matei V, Pauley S, Kaing S, Rowitch D, Beisel KW, Morris K, Feng F, Jones K, Lee J, Fritzsch B (2005) Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn 234:633-650.
16. McKenzie E, Krupin A, Kelley MW (2004) Cellular growth and rearrangement during the development of the mammalian organ of Corti. Dev Dyn 229:802-812.
17. Montcouquiol M, Rachel RA, Lanford PJ, Copeland NG, Jenkins NA, Kelley MW (2003) Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423:173-177.
18. Montcouquiol M, Sans N, Huss D, Kach J, Dickman JD, Forge A, Rachel RA, Copeland NG, Jenkins NA, Bogani D, Murdoch J, Warchol ME, Wenthold RJ, Kelley MW (2006) Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals. J Neurosci 26:5265-5275.
19. Morsli H, Choo D, Ryan A, Johnson R, Wu DK (1998) Development of the mouse inner ear and origin of its sensory organs. J Neurosci 18:3327-3335.
20. Pauley S, Lai E, Fritzsch B (2006) Foxg1 is required for morphogenesis and histogenesis of the mammalian inner ear. Dev Dyn 235:2470-2482.
21. Phippard D, Lu L, Lee D, Saunders JC, Crenshaw III EB (1999) Targeted mutagenesis of the POU-domain gene Brn4/Pou3f4 causes developmental defects in the inner ear. J Neurosci 19:5980-5989.
22. Pirrotta V, Poux S, Melfi R, Pilyugin M (2003) Assembly of Polycomb complexes and silencing mechanisms. Genetica 117:191-197.
23. Qian D, Jones C, Rzadzinska A, Mark S, Zhang X, Steel KP, Dai X, Chen P (2007) Wnt5a functions in planar cell polarity regulation in mice. Dev Biol 306:121-133.
24. Ringrose L, Paro R (2004) Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet 38:413-443.
25. Ruben RJ (1967) Development of the inner ear of the mouse: a radioautographic study of terminal mitoses. Acta Otolaryngol Suppl 220:1-44.
26. Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond Jr RM, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, et al. (2004) SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes. Proc Natl Acad Sci USA 101:8090-8095.
27. Southard JL (1970) Jackson circler, jc. Mouse News Letters 42:30.
28. Steel KP, Kros CJ (2001) A genetic approach to understanding auditory function. Nat Genet 27:143-149.
29. Wang J, Mark S, Zhang X, Qian D, Yoo SJ, Radde-Gallwitz K, Zhang Y, Lin X, Collazo A, Wynshaw-Boris A, Chen P (2005) Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet 37:980-985.
30. Wu DK, Oh SH (1996) Sensory organ generation in the chick inner ear. J Neurosci 16:6454-6462.
31. Zhang H, Christoforou A, Aravind L, Emmons SW, van den Heuvel S, Haber DA (2004) The C. elegans Polycomb gene SOP-2 encodes an RNA binding protein. Mol Cell 14:841-847.
32. Zheng W, Huang L, Wei ZB, Silvius D, Tang B, Xu PX (2003) The role of Six1 in mammalian auditory system development. Development 130:3989-4000.