Rapid human melanoma cell death induced by sanguinarine through oxidative stress

European Journal of Pharmacology

Volumn 705, Issue 1-3, 2013, Pages 109-118

  Burgeiro, Ana ^a,b,c   Bento, Ana C ^a   Gajate, Consuelo ^a   Oliveira, Paulo J ^b   Mollinedo, Faustino ^a  

^a Centro de Investigacion del Cancer   (Spain)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Caspase activation; Endoplasmic reticulum; Human melanoma cells; Mitochondria; Oxidative stress; Sanguinarine

Indexed keywords

ACETYLCYSTEINE; BAP 31 PROTEIN; BETA ACTIN; CALCIUM; CASPASE 10; CASPASE 3; CASPASE 4; CASPASE 7; CASPASE 8; CASPASE 9; CYTOCHROME C; DANTROLENE; DNA; GLUTATHIONE; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL XL; SANGUINARINE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL KILLING; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DNA DEGRADATION; DRUG CYTOTOXICITY; DRUG INHIBITION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME RELEASE; GENE OVEREXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; MELANOMA; MELANOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR INTERACTION; ONCOGENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; TIME-LAPSE VIDEO MICROSCOPY;

ACETYLCYSTEINE; ANTINEOPLASTIC AGENTS; BCL-X PROTEIN; BENZOPHENANTHRIDINES; CALCIUM; CASPASE 3; CASPASE 7; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; GLUTATHIONE; HUMANS; ISOQUINOLINES; MELANOMA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE PROTEINS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84875293604     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.02.035     Document Type: Article

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